DE69626022D1 - Verfahren zur industriellen herstellung eines japanischen enkephalitis impfstoffes, und so erhaltener impfstoff - Google Patents
Verfahren zur industriellen herstellung eines japanischen enkephalitis impfstoffes, und so erhaltener impfstoffInfo
- Publication number
- DE69626022D1 DE69626022D1 DE69626022T DE69626022T DE69626022D1 DE 69626022 D1 DE69626022 D1 DE 69626022D1 DE 69626022 T DE69626022 T DE 69626022T DE 69626022 T DE69626022 T DE 69626022T DE 69626022 D1 DE69626022 D1 DE 69626022D1
- Authority
- DE
- Germany
- Prior art keywords
- vaccine
- pct
- virus
- cells
- japanese encephalitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 2
- 238000009776 industrial production Methods 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 4
- 239000000725 suspension Substances 0.000 abstract 3
- 229940124726 Japanese encephalitis vaccine Drugs 0.000 abstract 2
- 241000710842 Japanese encephalitis virus Species 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 108091092356 cellular DNA Proteins 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000004255 ion exchange chromatography Methods 0.000 abstract 1
- 230000000644 propagated effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24151—Methods of production or purification of viral material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9509374A FR2737412B1 (fr) | 1995-08-01 | 1995-08-01 | Procede de production d'un vaccin contre le virus de l'encephalite japonaise et vaccin obtenu par ce procede |
FR9509374 | 1995-08-01 | ||
FR9603638A FR2746411B3 (fr) | 1996-03-22 | 1996-03-22 | Procede de production industrielle d'un vaccin contre l'encephalite japonaise et vaccin obtenu |
FR9603638 | 1996-03-22 | ||
PCT/FR1996/001195 WO1997004803A1 (fr) | 1995-08-01 | 1996-07-29 | Procede de production industrielle d'un vaccin contre l'encephalite japonaise et vaccin obtenu |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69626022D1 true DE69626022D1 (de) | 2003-03-06 |
DE69626022T2 DE69626022T2 (de) | 2003-09-11 |
DE69626022T3 DE69626022T3 (de) | 2008-05-08 |
Family
ID=26232139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1996626022 Expired - Lifetime DE69626022T3 (de) | 1995-08-01 | 1996-07-29 | Verfahren zur industriellen herstellung eines japanischen enkephalitis impfstoffes, und so erhaltener impfstoff |
Country Status (11)
Country | Link |
---|---|
US (1) | US6149917A (de) |
EP (1) | EP0841942B2 (de) |
JP (1) | JPH11510151A (de) |
KR (1) | KR19990036028A (de) |
CN (1) | CN1122531C (de) |
AT (1) | ATE231729T1 (de) |
AU (1) | AU709584B2 (de) |
CA (1) | CA2228128C (de) |
DE (1) | DE69626022T3 (de) |
NZ (1) | NZ315357A (de) |
WO (1) | WO1997004803A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1760151B1 (de) | 1996-11-20 | 2012-03-21 | Crucell Holland B.V. | Adenovirus-Zusammensetzungen erhältlich durch ein verbessertes Produktions- und Reinigungsverfahren |
US7732129B1 (en) | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
US6207439B1 (en) | 1997-03-25 | 2001-03-27 | Center For Disease Control | Purification of Japanese encephalitis virus |
TW570803B (en) * | 1997-04-09 | 2004-01-11 | Duphar Int Res | Influenza vaccine |
JP2000083657A (ja) * | 1998-07-13 | 2000-03-28 | Chemo Sero Therapeut Res Inst | 日本脳炎ウイルスワクチン |
EP1057889B1 (de) | 1998-10-05 | 2009-04-22 | The Research Foundation for Microbial Diseases of Osaka University | Verbessertes immunogen für inaktivierten impfstoff gegen infektion mit japanischen encephalitis viren und verfahren zu dessen herstellung |
US6689600B1 (en) | 1998-11-16 | 2004-02-10 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
AU4472801A (en) * | 2000-04-07 | 2001-10-23 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Inactivated japanese B encephalitis vaccine and process for producing the same |
WO2002077206A1 (en) * | 2001-03-27 | 2002-10-03 | Vertex Pharmaceuticals Incorporated | Compositiona and methods useful for hcv infection |
CN1305526C (zh) * | 2003-12-29 | 2007-03-21 | 薛平 | 乙型脑炎病毒裂解疫苗及其制备方法 |
JP2008518632A (ja) | 2004-11-03 | 2008-06-05 | イントロゲン セラピューティックス, インコーポレイテッド | アデノウイルスベクターの製造および精製のための新規方法 |
EP1724338A1 (de) * | 2005-05-19 | 2006-11-22 | Crucell Holland B.V. | Methode zur Herstellung eines Impfstoffs aus inaktiviertem ganzem Westnilvirus |
WO2006122964A1 (en) * | 2005-05-19 | 2006-11-23 | Crucell Holland B.V. | Methods for the production of a whole-inactivated west nile virus vaccine |
JP5580600B2 (ja) | 2007-12-26 | 2014-08-27 | 北里第一三共ワクチン株式会社 | 安定に長期間保存できる日本脳炎ワクチンの製法方法及び該ワクチンの用途 |
KR20120027381A (ko) * | 2009-05-25 | 2012-03-21 | 파나세아 바이오테크 리미티드 | 일본뇌염 백신 및 그것의 제조 방법 |
JP5716297B2 (ja) | 2009-06-25 | 2015-05-13 | Jnc株式会社 | クロマトグラフィー用充填剤、その製造方法、およびそれを用いたウイルス用ワクチンの製造方法 |
TWI627281B (zh) * | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物 |
CN102327608B (zh) * | 2010-08-27 | 2013-03-27 | 丽珠集团疫苗工程股份有限公司 | 一种乙型脑炎疫苗的纯化方法 |
WO2012110490A1 (en) * | 2011-02-17 | 2012-08-23 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
EP2968513A2 (de) | 2013-03-15 | 2016-01-20 | Boehringer Ingelheim Vetmedica, Inc. | Prrs-virus, zusammensetzungen, impfstoff und verfahren zur verwendung |
AU2017207076B2 (en) * | 2016-01-15 | 2021-04-29 | Km Biologics Co., Ltd. | Vaccine containing immobilized virus particles |
WO2018161858A1 (en) | 2017-03-06 | 2018-09-13 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
EP3420076B1 (de) | 2017-03-06 | 2024-02-21 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Verfahren zur herstellung und charakterisierung eines virusimpfstoffes und einer virenimpfstoffzusammensetzung |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6147185A (ja) * | 1984-08-09 | 1986-03-07 | Chemo Sero Therapeut Res Inst | 日本脳炎ウイルスの精製方法 |
US4637936A (en) * | 1984-08-10 | 1987-01-20 | Marlen Research Corporation | Aspetic food processing apparatus and method |
AT393356B (de) * | 1989-12-22 | 1991-10-10 | Immuno Ag | Verfahren zur herstellung von fsme-virus-antigen |
CA2047041A1 (en) † | 1990-07-18 | 1992-01-19 | John A. Lewis | Process for purification of hepatitis-a virus capsids |
GB9022547D0 (en) † | 1990-10-17 | 1990-11-28 | Wellcome Found | Purified immunoglobulin |
JPH06153227A (ja) † | 1992-10-29 | 1994-05-31 | Victor Co Of Japan Ltd | カラー信号補正回路 |
CN1063970C (zh) * | 1994-12-06 | 2001-04-04 | 卫生部北京生物制品研究所 | 用鳞翅目粘虫卵巢细胞制备流行性乙脑疫苗的方法及疫苗 |
-
1996
- 1996-07-29 EP EP96927102A patent/EP0841942B2/de not_active Expired - Lifetime
- 1996-07-29 WO PCT/FR1996/001195 patent/WO1997004803A1/fr active IP Right Grant
- 1996-07-29 AU AU67041/96A patent/AU709584B2/en not_active Expired
- 1996-07-29 CA CA 2228128 patent/CA2228128C/fr not_active Expired - Fee Related
- 1996-07-29 US US09/000,263 patent/US6149917A/en not_active Expired - Lifetime
- 1996-07-29 NZ NZ31535796A patent/NZ315357A/xx not_active IP Right Cessation
- 1996-07-29 DE DE1996626022 patent/DE69626022T3/de not_active Expired - Lifetime
- 1996-07-29 AT AT96927102T patent/ATE231729T1/de not_active IP Right Cessation
- 1996-07-29 CN CN96196620A patent/CN1122531C/zh not_active Expired - Lifetime
- 1996-07-29 JP JP50729097A patent/JPH11510151A/ja active Pending
- 1996-07-29 KR KR1019980700693A patent/KR19990036028A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR19990036028A (ko) | 1999-05-25 |
DE69626022T3 (de) | 2008-05-08 |
EP0841942A1 (de) | 1998-05-20 |
CN1194584A (zh) | 1998-09-30 |
DE69626022T2 (de) | 2003-09-11 |
CA2228128C (fr) | 2011-03-29 |
AU6704196A (en) | 1997-02-26 |
CA2228128A1 (fr) | 1997-02-13 |
US6149917A (en) | 2000-11-21 |
AU709584B2 (en) | 1999-09-02 |
WO1997004803A1 (fr) | 1997-02-13 |
CN1122531C (zh) | 2003-10-01 |
EP0841942B1 (de) | 2003-01-29 |
NZ315357A (en) | 1999-08-30 |
EP0841942B2 (de) | 2007-12-12 |
JPH11510151A (ja) | 1999-09-07 |
ATE231729T1 (de) | 2003-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: SANOFI PASTEUR, LYON, FR |