JP2004529161A5 - - Google Patents

Download PDF

Info

Publication number
JP2004529161A5
JP2004529161A5 JP2002586869A JP2002586869A JP2004529161A5 JP 2004529161 A5 JP2004529161 A5 JP 2004529161A5 JP 2002586869 A JP2002586869 A JP 2002586869A JP 2002586869 A JP2002586869 A JP 2002586869A JP 2004529161 A5 JP2004529161 A5 JP 2004529161A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
hydrogen
group
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002586869A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004529161A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/013856 external-priority patent/WO2002089729A2/en
Publication of JP2004529161A publication Critical patent/JP2004529161A/ja
Publication of JP2004529161A5 publication Critical patent/JP2004529161A5/ja
Pending legal-status Critical Current

Links

JP2002586869A 2001-05-04 2002-05-03 縮合複素環式化合物 Pending JP2004529161A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28866501P 2001-05-04 2001-05-04
PCT/US2002/013856 WO2002089729A2 (en) 2001-05-04 2002-05-03 Fused heterocyclic compounds

Publications (2)

Publication Number Publication Date
JP2004529161A JP2004529161A (ja) 2004-09-24
JP2004529161A5 true JP2004529161A5 (enExample) 2005-12-22

Family

ID=23108101

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002586869A Pending JP2004529161A (ja) 2001-05-04 2002-05-03 縮合複素環式化合物

Country Status (9)

Country Link
US (1) US6858619B2 (enExample)
EP (1) EP1392298B1 (enExample)
JP (1) JP2004529161A (enExample)
AT (1) ATE422887T1 (enExample)
AU (1) AU2002305323A1 (enExample)
CA (1) CA2446351A1 (enExample)
DE (1) DE60231202D1 (enExample)
ES (1) ES2319619T3 (enExample)
WO (1) WO2002089729A2 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858619B2 (en) 2001-05-04 2005-02-22 Amgen Inc. Fused heterocyclic compounds
US20070135425A1 (en) * 2001-05-04 2007-06-14 Amgen Inc. Fused heterocyclic compounds
US6809104B2 (en) 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
US7084156B2 (en) * 2001-11-27 2006-08-01 Merck & Co., Inc. 2-Aminoquinoline compounds
CA2468159A1 (en) * 2001-11-27 2003-06-05 Merck & Co., Inc. 4-aminoquinoline compounds
WO2003059289A2 (en) 2002-01-10 2003-07-24 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues
US7160879B2 (en) 2002-01-10 2007-01-09 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 2-(4-benzyl-piperazin-1-ylmethyl)- and 2-(4-benzyl-diazepan-1-ylmethyl)-1H-benzoimidazole analogues
ZA200503654B (en) * 2002-11-06 2006-09-27 Amgen Inc Fused heterocyclic compounds
US7727998B2 (en) * 2003-02-10 2010-06-01 Banyu Pharmaceutical Co., Ltd. Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
US7319108B2 (en) 2004-01-25 2008-01-15 Sanofi-Aventis Deutschland Gmbh Aryl-substituted heterocycles, process for their preparation and their use as medicaments
DE102004039789A1 (de) 2004-08-16 2006-03-02 Sanofi-Aventis Deutschland Gmbh Arylsubstituierte polycyclische Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
AU2006298852A1 (en) 2005-09-30 2007-04-12 F. Hoffmann-La Roche Ag Indane derivatives as MCH receptor antagonists
ATE495157T1 (de) 2006-02-15 2011-01-15 Sanofi Aventis Neue aminoalkohol-substituierte aryldihydroisochinolinone, herstellungsverfahren und ihre verwendung als medikamente
AU2007283113A1 (en) 2006-08-08 2008-02-14 Sanofi-Aventis Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
UY31968A (es) 2008-07-09 2010-01-29 Sanofi Aventis Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
TW201040154A (en) 2009-02-13 2010-11-16 Sanofi Aventis Novel substituted indanes, process for preparation thereof and use thereof as a medicament
UY32443A (es) 2009-02-13 2010-09-30 Sanofi Aventis Nuevos tetrahidronaftalenos, procesos para su preparación y uso de los mismos como medicamento.
KR20120060207A (ko) 2009-08-26 2012-06-11 사노피 신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
US8575186B2 (en) * 2009-10-05 2013-11-05 Albany Molecular Research, Inc. Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
CA2823955A1 (en) 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8809325B2 (en) 2011-03-08 2014-08-19 Sanofi Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120058A1 (de) 2011-03-08 2012-09-13 Sanofi Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8710050B2 (en) 2011-03-08 2014-04-29 Sanofi Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
CN104487070A (zh) * 2012-03-16 2015-04-01 格卢科克斯生物科技有限公司 显示nox4抑制活性的基于噻吩的化合物及其用于治疗的用途
JP6274384B2 (ja) * 2012-04-27 2018-02-07 Nok株式会社 メタルガスケット及びその製造方法
EP3870292A4 (en) 2018-10-26 2022-11-09 The Research Foundation for The State University of New York COMBINATION OF SEROTONIN-SPECIFIC RESUPPUT INHIBITOR AND SEROTONIN 1A RECEPTOR PARTIAL AGONIST TO REDUCE L-DOPA-INDUCED DYSKINESIA

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2906654B2 (ja) 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
US5441956A (en) * 1991-07-05 1995-08-15 Smithkline Beecham Farmaceutici S.P.A. Hydroisoquinoline derivatives
WO1994007896A1 (fr) 1992-09-29 1994-04-14 Toray Industries, Inc. Derive indole, procede pour sa fabrication, et son usage medicinal
US5464841A (en) 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
US5578725A (en) 1995-01-30 1996-11-26 Regents Of The University Of Minnesota Delta opioid receptor antagonists
NZ331769A (en) 1997-01-16 2000-05-26 Toray Industries Indolomorphinan derivative and agent for curing and preventing cerebral disorder
JP3886030B2 (ja) 1998-10-07 2007-02-28 シャープ株式会社 半導体レーザ素子
GB9822158D0 (en) 1998-10-09 1998-12-02 Nycomed Imaging As Compositions
AU2573900A (en) 1999-02-19 2000-09-04 Takeda Chemical Industries Ltd. Novel g protein-coupled receptor protein and dna thereof
WO2001007606A1 (en) 1999-07-27 2001-02-01 Smithkline Beecham Plc Axor21, a g-protein coupled receptor
JP2001226269A (ja) 2000-02-18 2001-08-21 Takeda Chem Ind Ltd メラニン凝集ホルモン拮抗剤
CA2408913A1 (en) 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist
EP1299362A4 (en) 2000-07-05 2004-11-03 Synaptic Pharma Corp SELECTIVE RECEPTOR ANTAGONISTS OF MELANINE CONCENTRATING HORMON-1 (MCH1) AND THEIR USE
WO2002002744A2 (en) 2000-07-05 2002-01-10 Synaptic Pharmaceutical Corporation Dna encoding a human melanin concentrating hormone receptor (mch1) and uses thereof
WO2002003070A1 (en) 2000-07-05 2002-01-10 Takeda Chemical Industries, Ltd. Method for screening mch receptor antagonist/agonist
MXPA03000174A (es) 2000-07-06 2003-09-22 Neurogen Corp Ligandos de receptor de hormona concentradora de melanina.
CN1469876A (zh) 2000-10-20 2004-01-21 �Ʒ� α-芳基乙醇胺及其用作β-3肾上腺素能受体激动剂的用途
US20030022891A1 (en) 2000-12-01 2003-01-30 Anandan Palani MCH antagonists and their use in the treatment of obesity
US6472394B1 (en) 2000-12-22 2002-10-29 Schering Corporation MCH antagonists and their use in the treatment of obesity
EP1370520A1 (en) 2001-03-21 2003-12-17 Pharmacopeia, Inc. Aryl and biaryl compounds having mch modulatory activity
US6900329B2 (en) 2001-03-21 2005-05-31 Schering Corporation MCH antagonists and their use in the treatment of obesity
JP4280073B2 (ja) 2001-04-12 2009-06-17 ファーマコペイア ドラッグ ディスカバリー， インコーポレイテッド Ｍｃｈアンタゴニストとして使用されるアリールピペリジンおよびビアリールピペリジン
US6858619B2 (en) 2001-05-04 2005-02-22 Amgen Inc. Fused heterocyclic compounds
JP2005515961A (ja) 2001-05-22 2005-06-02 ニューロジェン コーポレイション メラニン凝集ホルモン受容体リガンド：置換１−ベンジル−４−アリールピペラジン類似体

Similar Documents

Publication Publication Date Title
JP2004529161A5 (enExample)
JP4345230B2 (ja) カルボン酸誘導体およびその誘導体を有効成分として含有する薬剤
JP5697163B2 (ja) 置換された３−ヒドロキシ−４−ピリドン誘導体
CN1534023A (zh) 作为多巴胺－d3配位体的杂环化合物
CN1124269C (zh) 取代的嘧啶化合物和其用途
JP5985611B2 (ja) 炎症および免疫関連用途のための化合物
JPWO1999046232A1 (ja) カルボン酸誘導体およびその誘導体を有効成分として含有する薬剤
JP2007504284A5 (enExample)
JP2002520309A5 (enExample)
TW201124379A (en) Aryl substituted sulfonamide compounds and their use as anticancer agents
JP2005508967A5 (enExample)
JP2012236838A5 (enExample)
JP2009524611A5 (ja) Ｓ１ｐ１受容体アゴニスト、免疫抑制剤および抗炎症剤としての３，５ージ（アリールまたはヘテロアリール）イソキサゾールおよび１，２，４−オキサジアゾール
JP2016505063A (ja) ソルチリン阻害剤としてのｎ置換された５置換フタルアミド酸
CN1649819A (zh) 新的甲状腺素受体配体
CN1400969A (zh) 稠合的咪唑鎓衍生物
JP2004517813A5 (enExample)
CN105143188B (zh) 新型磺酰胺trpa1受体拮抗剂
CN103717593A (zh) 调节激酶的组合物和方法
JP2005511545A5 (enExample)
JP2005536519A5 (enExample)
JP2022539126A (ja) ベンゾジアゼピン系化合物及びその製造方法並びに医薬における作用
JPH10287651A5 (enExample)
JP2009502921A5 (enExample)
RU2004117595A (ru) Производные пиридина в качестве лигандов рецептора nmda