JP2004529079A5 - - Google Patents
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- JP2004529079A5 JP2004529079A5 JP2002549276A JP2002549276A JP2004529079A5 JP 2004529079 A5 JP2004529079 A5 JP 2004529079A5 JP 2002549276 A JP2002549276 A JP 2002549276A JP 2002549276 A JP2002549276 A JP 2002549276A JP 2004529079 A5 JP2004529079 A5 JP 2004529079A5
- Authority
- JP
- Japan
- Prior art keywords
- cox
- extract
- eyes
- composition
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 14
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 claims 13
- 108050003267 Prostaglandin G/H synthase 2 Proteins 0.000 claims 13
- 230000002401 inhibitory effect Effects 0.000 claims 7
- 230000000694 effects Effects 0.000 claims 6
- 230000001404 mediated effect Effects 0.000 claims 5
- 241000196324 Embryophyta Species 0.000 claims 4
- 102100038277 Prostaglandin G/H synthase 1 Human genes 0.000 claims 4
- 108050003243 Prostaglandin G/H synthase 1 Proteins 0.000 claims 4
- 235000002566 Capsicum Nutrition 0.000 claims 3
- 241000134884 Ericales Species 0.000 claims 3
- 240000008574 Capsicum frutescens Species 0.000 claims 2
- 241000207832 Lamiales Species 0.000 claims 2
- 241000219171 Malpighiales Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 241000220221 Rosales Species 0.000 claims 2
- 241000208292 Solanaceae Species 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000001390 capsicum minimum Substances 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 241000881711 Acipenser sturio Species 0.000 claims 1
- 241000756998 Alismatales Species 0.000 claims 1
- 241000208837 Asterales Species 0.000 claims 1
- 241001072256 Boraginaceae Species 0.000 claims 1
- 241000218980 Brassicales Species 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 241000219504 Caryophyllales Species 0.000 claims 1
- 241000196114 Cycadales Species 0.000 claims 1
- 241000219427 Fagales Species 0.000 claims 1
- 240000000731 Fagus sylvatica Species 0.000 claims 1
- 235000010099 Fagus sylvatica Nutrition 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 241000234269 Liliales Species 0.000 claims 1
- 241000234435 Lilium Species 0.000 claims 1
- 241000134886 Myrtales Species 0.000 claims 1
- 241000238413 Octopus Species 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 241000123637 Pandanales Species 0.000 claims 1
- 240000001090 Papaver somniferum Species 0.000 claims 1
- 235000008753 Papaver somniferum Nutrition 0.000 claims 1
- 239000006002 Pepper Substances 0.000 claims 1
- 235000004347 Perilla Nutrition 0.000 claims 1
- 244000124853 Perilla frutescens Species 0.000 claims 1
- 235000016761 Piper aduncum Nutrition 0.000 claims 1
- 235000017804 Piper guineense Nutrition 0.000 claims 1
- 244000203593 Piper nigrum Species 0.000 claims 1
- 235000008184 Piper nigrum Nutrition 0.000 claims 1
- 241000758713 Piperales Species 0.000 claims 1
- 206010037660 Pyrexia Diseases 0.000 claims 1
- 241000134888 Santalales Species 0.000 claims 1
- 240000000513 Santalum album Species 0.000 claims 1
- 235000008632 Santalum album Nutrition 0.000 claims 1
- 241000134968 Sapindales Species 0.000 claims 1
- 235000002634 Solanum Nutrition 0.000 claims 1
- 241000207763 Solanum Species 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 208000015114 central nervous system disease Diseases 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30420700P | 2000-12-15 | 2000-12-15 | |
| PCT/US2001/048650 WO2002047706A2 (en) | 2000-12-15 | 2001-12-13 | Selective cox-2 inhibition from plant extracts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004529079A JP2004529079A (ja) | 2004-09-24 |
| JP2004529079A5 true JP2004529079A5 (https=) | 2006-01-12 |
Family
ID=23175530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002549276A Withdrawn JP2004529079A (ja) | 2000-12-15 | 2001-12-13 | 植物抽出物による選択的cox−2阻害 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20020136784A1 (https=) |
| EP (1) | EP1401460A2 (https=) |
| JP (1) | JP2004529079A (https=) |
| AU (1) | AU2002229074A1 (https=) |
| WO (1) | WO2002047706A2 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7108868B2 (en) | 2002-03-22 | 2006-09-19 | Unigen Pharmaceuticals, Inc. | Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia |
| US7972632B2 (en) | 2003-02-28 | 2011-07-05 | Unigen Pharmaceuticals, Inc. | Identification of Free-B-Ring flavonoids as potent COX-2 inhibitors |
| US20030165588A1 (en) | 2002-03-01 | 2003-09-04 | Unigen Pharmaceuticals, Inc. | Identification of free-B-ring flavonoids as potent COX-2 inhibitors |
| US8034387B2 (en) * | 2002-04-30 | 2011-10-11 | Unigen, Inc. | Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments |
| US8945518B2 (en) * | 2002-04-30 | 2015-02-03 | Unigen, Inc. | Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions |
| CN101837003B (zh) | 2002-04-30 | 2013-09-04 | 尤尼根公司 | 作为治疗剂的包含无取代b环类黄酮和黄烷混合物的组合物 |
| JP2004196696A (ja) * | 2002-12-18 | 2004-07-15 | Kyowa Hakko Kogyo Co Ltd | 関節炎の予防剤または治療剤 |
| FR2851919A1 (fr) * | 2003-03-03 | 2004-09-10 | Lmd | Lignanes utilisables comme inhibiteurs de cathepsines et leurs applications |
| BRPI0409179A (pt) * | 2003-04-04 | 2006-05-02 | Unigen Pharmaceuticals Inc | formulação de inibidores duplos de ciclooxigenase (cox) e lipoxigenase (lox) para cuidados com a pele de mamìferos |
| FR2854799A1 (fr) * | 2003-05-16 | 2004-11-19 | Cognis France Sa | Utilisation d'extraits des graines de plantes appartenant au genre adenanthera pour la fabrication de preparations cosmetiques et/ou dermatologiques |
| MXPA06002456A (es) * | 2003-09-02 | 2006-08-31 | Unigen Pharmaceuticals Inc | Formulacion de una mezcla de flavonoides con el aniillo b libre y flavanos para utilizarse en la prevencion y tratamiento de la declinacion cognoscitiva y el deterioro de la memoria relacionado con la edad. |
| BR0318678A (pt) * | 2003-12-22 | 2006-11-28 | Council Scient Ind Res | uma composição sinérgetica para tratamento de hiperlipidemia |
| JP4836418B2 (ja) * | 2004-07-29 | 2011-12-14 | 丸善製薬株式会社 | 抗酸化剤、抗炎症剤、美白剤及び皮膚化粧料 |
| KR100545304B1 (ko) * | 2004-09-01 | 2006-05-08 | 주식회사 유니젠 | 아선약을 포함하는 운카리아 속 식물, 또는 이의 황금및/또는 녹차의 배합물을 포함하는 사이클로옥시게나제및/또는 5-리폭시게나제 억제용 조성물 |
| US20060198872A1 (en) * | 2005-03-07 | 2006-09-07 | Chioma Ikonte | Plant based dietary supplement for improving the duration and quality of sleep |
| CA2657803C (en) * | 2006-05-01 | 2019-01-08 | Napo Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer |
| US7282224B1 (en) | 2006-06-09 | 2007-10-16 | Guthy-Renker Corporation | Pain relief composition |
| KR100761248B1 (ko) | 2006-10-12 | 2007-10-04 | 주식회사 유니젠 | 대나무 및 황금 추출물을 유효성분으로 함유하는 아토피성피부염 치료를 위한 조성물 |
| US20080107747A1 (en) * | 2006-10-23 | 2008-05-08 | Roederer Joy E | Pain relief composition |
| KR100791108B1 (ko) | 2006-11-06 | 2008-01-03 | 제주대학교 산학협력단 | 방사선 방호효과를 갖는 담팔수 분획농축물과 그 제조방법 |
| FR2922765B1 (fr) * | 2007-10-25 | 2014-11-28 | Inst Rech Developpement Ird | Utilisation d'une huile essentielle pour la preparation d'une composition cosmetique ou pharmaceutique |
| KR100982022B1 (ko) * | 2008-03-11 | 2010-09-13 | 한동열 | 신경세포 손상의 예방 또는 치료용 조성물 |
| FR2943247B1 (fr) | 2009-03-20 | 2012-11-30 | Natura Cosmeticos Sa | Procede pour obtenir des substances insolubles a partir de precipites d'extrait de genipap, substances ainsi obtenues et leurs utilisations |
| KR101057483B1 (ko) | 2009-04-09 | 2011-08-17 | 한동열 | 9-히드록시-알파-토코페론을 포함하는 신경세포 손상의 예방 또는 치료용 조성물 |
| US8273387B2 (en) | 2009-08-26 | 2012-09-25 | Mary Kay Inc. | Topical skin formulations comprising plant extracts |
| KR101167677B1 (ko) * | 2009-09-21 | 2012-07-20 | 한국생명공학연구원 | 엘리오카퍼스 페티오라투스 추출물을 함유하는 염증성 질환 예방 및 치료용 조성물 |
| WO2012033634A2 (en) | 2010-09-09 | 2012-03-15 | Mary Kay Inc. | Topical skin care formulations comprising plant extracts |
| WO2012077976A2 (ko) * | 2010-12-07 | 2012-06-14 | 한국생명공학연구원 | 엘리오카퍼스 페티오라투스 추출물 또는 이의 분획물을 유효성분으로 함유하는 노화방지용 조성물 |
| KR101425560B1 (ko) * | 2010-12-07 | 2014-08-04 | 한국생명공학연구원 | 엘리오카퍼스 페티오라투스 추출물 또는 이의 분획물을 유효성분으로 함유하는 항산화용 조성물 |
| DE102011109522A1 (de) * | 2011-08-05 | 2013-02-07 | Merck Patent Gmbh | Extrakte aus Tradescantia virginiana |
| US8632827B2 (en) | 2011-12-13 | 2014-01-21 | Avon Products, Inc | Modulation of thymosin beta-4 in skin |
| US8709507B2 (en) | 2011-12-13 | 2014-04-29 | Avon Products, Inc. | Maesa japonica extracts and methods of use |
| TWI637751B (zh) * | 2012-12-11 | 2018-10-11 | 美商愛芳製品公司 | 山桂花(maesa japonica)萃取物及使用方法 |
| JP2014177454A (ja) * | 2013-02-18 | 2014-09-25 | Kagoshima Univ | ねじめびわ茶抽出物を含有する飲食品及び医薬品 |
| JP2016132633A (ja) * | 2015-01-19 | 2016-07-25 | 農業生産法人 有限会社十津川農場 | ねじめびわ茶のアルツハイマー症予防又は治療作用 |
| JP6485836B2 (ja) * | 2015-12-28 | 2019-03-20 | 株式会社佐藤園 | イグサ由来シクロオキシゲナーゼ−2阻害剤 |
| CN106994145B (zh) * | 2016-01-26 | 2022-05-03 | 财团法人工业技术研究院 | 用于治疗或减缓自体免疫疾病、其并发症和/或肾炎的医药组合物以及其有效成分之用途 |
| ES2883168T3 (es) | 2016-05-03 | 2021-12-07 | Tauderma Sa | Extractos de saxifraga para uso cosmético o terapéutico en la piel |
| KR101806031B1 (ko) | 2016-07-11 | 2017-12-08 | 한양대학교 에리카산학협력단 | 마카커진 c 또는 이의 유도체를 함유하는 항염증 활성 조성물 및 이의 제조방법 |
| KR102015448B1 (ko) * | 2017-12-08 | 2019-08-28 | 성균관대학교산학협력단 | 검팽나무 추출물을 유효성분으로 포함하는 항염증 조성물 |
| KR102284073B1 (ko) * | 2019-10-14 | 2021-08-02 | 한국해양과학기술원 | 항염증 활성을 갖는 남극 지의류 움빌리카리아 안타티카 추출물 및 이를 함유하는 조성물 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4324785A (en) * | 1980-05-20 | 1982-04-13 | Emma S. Stevens | Foot powder |
| US4313958A (en) * | 1980-10-24 | 1982-02-02 | The Procter & Gamble Company | Method of producing analgesia |
| JPS5824523A (ja) * | 1981-08-07 | 1983-02-14 | Terumo Corp | 抗悪性新生物剤 |
| JPS5936619A (ja) * | 1982-08-23 | 1984-02-28 | Tsumura Juntendo Inc | 制癌補助剤 |
| US4767626A (en) * | 1985-03-11 | 1988-08-30 | Theodore Cheng | Remedy for anemia and arthritis |
| US5380738A (en) * | 1993-05-21 | 1995-01-10 | Monsanto Company | 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents |
| US5344991A (en) * | 1993-10-29 | 1994-09-06 | G.D. Searle & Co. | 1,2 diarylcyclopentenyl compounds for the treatment of inflammation |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| ES2141916T3 (es) * | 1993-11-30 | 2000-04-01 | Searle & Co | Pirazolil-bencenosulfonamidas sustituidas para el tratamiento de la inflamacion. |
| US5393790A (en) * | 1994-02-10 | 1995-02-28 | G.D. Searle & Co. | Substituted spiro compounds for the treatment of inflammation |
| US5824312A (en) * | 1994-03-10 | 1998-10-20 | Imarx Pharmaceutical Corp. | Sunscreen agents from natural sources |
| US5633272A (en) * | 1995-02-13 | 1997-05-27 | Talley; John J. | Substituted isoxazoles for the treatment of inflammation |
| JP2732504B2 (ja) * | 1995-03-08 | 1998-03-30 | 農林水産省中国農業試験場長 | アラキドン酸代謝活性阻害剤とその製造法 |
| US5762963A (en) * | 1995-06-07 | 1998-06-09 | Emory University | Method and compositions for controlling oral and pharyngeal pain using capsaicinoids |
| JPH0967360A (ja) * | 1995-08-28 | 1997-03-11 | Terumo Corp | 癌遺伝子機能抑制剤 |
| SK285353B6 (sk) * | 1996-04-12 | 2006-11-03 | G. D. Searle & Co. | Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia |
| DK1007067T3 (da) * | 1996-10-21 | 2002-05-06 | Eurovita As | Farmaceutiske præparater indeholdende Parthenium integrifolium eller dele deraf eller en ekstrakt bestanddel deraf, anvendelsen af et sådant plantemateriale til fremstilling af ... |
| US5811425A (en) * | 1997-03-04 | 1998-09-22 | Abbott Laboratories | Heterocyclic compounds as COX-2 inhibitors |
| JP4231559B2 (ja) * | 1997-04-23 | 2009-03-04 | オリザ油化株式会社 | リポキシゲナーゼ阻害剤 |
| EP0984781A1 (en) * | 1997-05-27 | 2000-03-15 | Algos Pharmaceutical Corporation | Analgesic drug composition containing a capsaicinoid and potentiator therefor |
| AUPP797598A0 (en) * | 1998-12-30 | 1999-01-28 | Butters, Desley | Therapeutic agent |
| US6194469B1 (en) * | 1998-12-11 | 2001-02-27 | Board Of Trustees Operating Michigan State Univeristy | Method for inhibiting cyclooxygenase and inflammation using cherry bioflavonoids |
| JP4397991B2 (ja) * | 1999-02-16 | 2010-01-13 | 株式会社ロッテ | 抗発癌プロモーター剤 |
| US20010006686A1 (en) * | 1999-03-19 | 2001-07-05 | David G. Corley | Inflammatory mediation obtained from atractylodes lancea |
| JP2003500452A (ja) * | 1999-05-27 | 2003-01-07 | アーマディーロ・ファーマシューティカルス・インコーポレーテッド | 天然資源から抽出した生物活性物質の医薬製剤 |
| US6197823B1 (en) * | 1999-09-29 | 2001-03-06 | Medical Merchandising, Inc. | Pain reliever and method of use |
| US6348501B1 (en) * | 1999-09-29 | 2002-02-19 | Medical Merchandising, Inc. | Lotion compositions utilizing capsaicin |
| US6310091B1 (en) * | 2000-09-14 | 2001-10-30 | The United States Of America As Represented By The Secretary Of Agriculture | Fungicidal saponin, CAY-1, and isolation thereof from Capsium species fruit |
-
2001
- 2001-12-13 WO PCT/US2001/048650 patent/WO2002047706A2/en not_active Ceased
- 2001-12-13 US US10/022,862 patent/US20020136784A1/en not_active Abandoned
- 2001-12-13 EP EP01990211A patent/EP1401460A2/en not_active Withdrawn
- 2001-12-13 AU AU2002229074A patent/AU2002229074A1/en not_active Abandoned
- 2001-12-13 JP JP2002549276A patent/JP2004529079A/ja not_active Withdrawn
-
2004
- 2004-04-02 US US10/817,027 patent/US20040197429A1/en not_active Abandoned
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