JP2004527264A5 - - Google Patents
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- Publication number
- JP2004527264A5 JP2004527264A5 JP2003500240A JP2003500240A JP2004527264A5 JP 2004527264 A5 JP2004527264 A5 JP 2004527264A5 JP 2003500240 A JP2003500240 A JP 2003500240A JP 2003500240 A JP2003500240 A JP 2003500240A JP 2004527264 A5 JP2004527264 A5 JP 2004527264A5
- Authority
- JP
- Japan
- Prior art keywords
- influenza virus
- inactivated
- influenza
- preparation
- virus preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 claims 18
- 241000712461 unidentified influenza virus Species 0.000 claims 13
- 239000000427 antigen Substances 0.000 claims 9
- 102000036639 antigens Human genes 0.000 claims 9
- 108091007433 antigens Proteins 0.000 claims 9
- 101710154606 Hemagglutinin Proteins 0.000 claims 6
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 6
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 6
- 101710176177 Protein A56 Proteins 0.000 claims 6
- 239000000185 hemagglutinin Substances 0.000 claims 6
- IELOKBJPULMYRW-NJQVLOCASA-N D-alpha-Tocopheryl Acid Succinate Chemical compound OC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C IELOKBJPULMYRW-NJQVLOCASA-N 0.000 claims 4
- 229940099418 d- alpha-tocopherol succinate Drugs 0.000 claims 4
- 206010022000 influenza Diseases 0.000 claims 4
- 229960003971 influenza vaccine Drugs 0.000 claims 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 4
- 229940087168 alpha tocopherol Drugs 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 claims 2
- 229960004906 thiomersal Drugs 0.000 claims 2
- 229960000984 tocofersolan Drugs 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 210000000605 viral structure Anatomy 0.000 claims 2
- 239000002076 α-tocopherol Substances 0.000 claims 2
- 235000004835 α-tocopherol Nutrition 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0113083A GB0113083D0 (en) | 2001-05-30 | 2001-05-30 | Novel compounds |
| GB0204116A GB0204116D0 (en) | 2002-02-21 | 2002-02-21 | Novel vaccine composition |
| PCT/EP2002/005883 WO2002097072A2 (en) | 2001-05-30 | 2002-05-29 | Influenza vaccine composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004527264A JP2004527264A (ja) | 2004-09-09 |
| JP2004527264A5 true JP2004527264A5 (https=) | 2005-12-22 |
| JP4074582B2 JP4074582B2 (ja) | 2008-04-09 |
Family
ID=30445235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003500240A Expired - Lifetime JP4074582B2 (ja) | 2001-05-30 | 2002-05-29 | 新規なワクチン |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US7316813B2 (https=) |
| EP (3) | EP2495314A1 (https=) |
| JP (1) | JP4074582B2 (https=) |
| KR (1) | KR100871021B1 (https=) |
| CN (2) | CN1279165C (https=) |
| AR (1) | AR036039A1 (https=) |
| AT (1) | ATE420159T1 (https=) |
| AU (2) | AU2006200742C9 (https=) |
| BR (1) | BRPI0210076B8 (https=) |
| CA (1) | CA2448208C (https=) |
| CO (1) | CO5540349A2 (https=) |
| CY (1) | CY1108930T1 (https=) |
| CZ (1) | CZ298697B6 (https=) |
| DE (1) | DE60230760D1 (https=) |
| DK (1) | DK1407008T3 (https=) |
| ES (1) | ES2318020T3 (https=) |
| FR (1) | FR13C0072I1 (https=) |
| HU (1) | HU229368B1 (https=) |
| IL (2) | IL158931A (https=) |
| MX (1) | MXPA03010944A (https=) |
| MY (1) | MY134424A (https=) |
| NO (1) | NO335212B1 (https=) |
| NZ (1) | NZ529755A (https=) |
| PL (1) | PL206435B1 (https=) |
| PT (1) | PT1407008E (https=) |
| SI (1) | SI1407008T1 (https=) |
| TW (1) | TWI228420B (https=) |
| WO (1) | WO2002097072A2 (https=) |
| ZA (1) | ZA200309250B (https=) |
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| US20060110406A1 (en) | 2003-02-25 | 2006-05-25 | Medimmune Vaccines, Inc. | Refrigerator-temperature stable influenza vaccine compositions |
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| JP2008512443A (ja) | 2004-09-09 | 2008-04-24 | カイロン ベーリング ゲーエムベーハー アンド カンパニー | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
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