JP2004267216A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004267216A5 JP2004267216A5 JP2004132989A JP2004132989A JP2004267216A5 JP 2004267216 A5 JP2004267216 A5 JP 2004267216A5 JP 2004132989 A JP2004132989 A JP 2004132989A JP 2004132989 A JP2004132989 A JP 2004132989A JP 2004267216 A5 JP2004267216 A5 JP 2004267216A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- coupled receptor
- polypeptide
- amino acid
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229920001184 polypeptide Polymers 0.000 claims 17
- 102000004196 processed proteins & peptides Human genes 0.000 claims 17
- 108090000765 processed proteins & peptides Proteins 0.000 claims 17
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 claims 16
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 claims 16
- 239000002157 polynucleotide Substances 0.000 claims 15
- 102000040430 polynucleotide Human genes 0.000 claims 15
- 108091033319 polynucleotide Proteins 0.000 claims 15
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 239000013598 vector Substances 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 108091006027 G proteins Proteins 0.000 claims 2
- 102000030782 GTP binding Human genes 0.000 claims 2
- 108091000058 GTP-Binding Proteins 0.000 claims 2
- 238000007792 addition Methods 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 229940125425 inverse agonist Drugs 0.000 claims 2
- 210000000496 pancreas Anatomy 0.000 claims 2
- 239000004031 partial agonist Substances 0.000 claims 2
- 102000005962 receptors Human genes 0.000 claims 2
- 108020003175 receptors Proteins 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 238000005406 washing Methods 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000003757 reverse transcription PCR Methods 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
Applications Claiming Priority (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10921398P | 1998-11-20 | 1998-11-20 | |
| US12041699P | 1999-02-16 | 1999-02-16 | |
| US12185299P | 1999-02-26 | 1999-02-26 | |
| US12394999P | 1999-03-12 | 1999-03-12 | |
| US12394699P | 1999-03-12 | 1999-03-12 | |
| US13656799P | 1999-05-28 | 1999-05-28 | |
| US13713199P | 1999-05-28 | 1999-05-28 | |
| US13712799P | 1999-05-28 | 1999-05-28 | |
| US13643999P | 1999-05-28 | 1999-05-28 | |
| US13643699P | 1999-05-28 | 1999-05-28 | |
| US13643799P | 1999-05-28 | 1999-05-28 | |
| US14144899P | 1999-06-29 | 1999-06-29 | |
| US15655599P | 1999-09-29 | 1999-09-29 | |
| US15663499P | 1999-09-29 | 1999-09-29 | |
| US15665399P | 1999-09-29 | 1999-09-29 | |
| US15663399P | 1999-09-29 | 1999-09-29 | |
| US15729399P | 1999-10-01 | 1999-10-01 | |
| US15728299P | 1999-10-01 | 1999-10-01 | |
| US15728199P | 1999-10-01 | 1999-10-01 | |
| US15728099P | 1999-10-01 | 1999-10-01 | |
| US15729499P | 1999-10-01 | 1999-10-01 | |
| US41704499A | 1999-10-12 | 1999-10-12 | |
| US41676099A | 1999-10-12 | 1999-10-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584067A Division JP2003534767A (ja) | 1998-11-20 | 1999-10-13 | ヒトオーファンｇタンパク質共役型受容体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007129923A Division JP2007209352A (ja) | 1998-11-20 | 2007-05-15 | ヒトオーファンｇタンパク質共役型受容体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004267216A JP2004267216A (ja) | 2004-09-30 |
| JP2004267216A5 true JP2004267216A5 (OSRAM) | 2007-02-01 |
Family
ID=27586698
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584067A Withdrawn JP2003534767A (ja) | 1998-11-20 | 1999-10-13 | ヒトオーファンｇタンパク質共役型受容体 |
| JP2004132989A Withdrawn JP2004267216A (ja) | 1998-11-20 | 2004-04-28 | ヒトオーファンｇタンパク質共役型受容体 |
| JP2007129923A Pending JP2007209352A (ja) | 1998-11-20 | 2007-05-15 | ヒトオーファンｇタンパク質共役型受容体 |
| JP2008033839A Pending JP2008133300A (ja) | 1998-11-20 | 2008-02-14 | ヒトオーファンｇタンパク質共役型受容体 |
| JP2009159339A Withdrawn JP2009298791A (ja) | 1998-11-20 | 2009-07-03 | ヒトオーファンｇタンパク質共役型受容体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584067A Withdrawn JP2003534767A (ja) | 1998-11-20 | 1999-10-13 | ヒトオーファンｇタンパク質共役型受容体 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007129923A Pending JP2007209352A (ja) | 1998-11-20 | 2007-05-15 | ヒトオーファンｇタンパク質共役型受容体 |
| JP2008033839A Pending JP2008133300A (ja) | 1998-11-20 | 2008-02-14 | ヒトオーファンｇタンパク質共役型受容体 |
| JP2009159339A Withdrawn JP2009298791A (ja) | 1998-11-20 | 2009-07-03 | ヒトオーファンｇタンパク質共役型受容体 |
Country Status (12)
| Country | Link |
|---|---|
| EP (8) | EP1133559B1 (OSRAM) |
| JP (5) | JP2003534767A (OSRAM) |
| KR (5) | KR100765039B1 (OSRAM) |
| AT (3) | ATE301673T1 (OSRAM) |
| AU (2) | AU770056B2 (OSRAM) |
| CA (2) | CA2645717A1 (OSRAM) |
| DK (3) | DK1584683T3 (OSRAM) |
| ES (3) | ES2243095T3 (OSRAM) |
| IL (2) | IL142538A0 (OSRAM) |
| NZ (3) | NZ537625A (OSRAM) |
| PT (3) | PT1133559E (OSRAM) |
| WO (1) | WO2000031258A2 (OSRAM) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1067183B1 (en) * | 1998-03-12 | 2006-05-17 | Astellas Pharma Inc. | Novel g protein-coupled receptor proteins |
| US6071722A (en) * | 1998-04-24 | 2000-06-06 | Smithkline Beecham Corporation | Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1) |
| WO1999055733A1 (en) * | 1998-04-24 | 1999-11-04 | Smithkline Beecham Corporation | Cloning of a novel 7tm receptor axor-2 |
| WO2000026339A2 (en) * | 1998-11-03 | 2000-05-11 | Smithkline Beecham Corporation | Axor14, a g-protein coupled receptor |
| US20030017528A1 (en) | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| US7816492B2 (en) | 1998-11-20 | 2010-10-19 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors |
| USRE42190E1 (en) | 1998-11-20 | 2011-03-01 | Arena Pharmaceuticals, Inc. | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| EP1157038A4 (en) * | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
| US6620615B1 (en) | 1999-04-23 | 2003-09-16 | Curagen Corporation | G-protein coupled receptor—encoding nucleic acids |
| EP1189944A4 (en) * | 1999-06-21 | 2002-09-11 | Smithkline Beecham Corp | AXOR16, R CEPTEUR COUPL UNE PROT INE G |
| WO2001004292A1 (en) * | 1999-07-13 | 2001-01-18 | Merck Patent Gmbh | G-protein coupled receptor and dna sequences thereof |
| EP1198569A1 (en) * | 1999-07-30 | 2002-04-24 | MERCK PATENT GmbH | G-protein coupled receptor and dna sequences thereof |
| CA2382889A1 (en) * | 1999-08-27 | 2001-03-08 | Takuya Watanabe | Novel g protein-coupled receptor protein and dna thereof |
| US6998255B1 (en) | 1999-09-24 | 2006-02-14 | Solvay Pharmaceuticals B.V. | Human G-protein coupled receptor |
| GB9923177D0 (en) * | 1999-09-30 | 1999-12-01 | Pfizer Ltd | Novel polypeptide |
| US6204017B1 (en) * | 1999-10-07 | 2001-03-20 | Schering Corporation | Polynucleotide encoding a histamine receptor |
| GB9923890D0 (en) * | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9923893D0 (en) * | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9924960D0 (en) * | 1999-10-21 | 1999-12-22 | Pfizer Ltd | Novel polypeptide |
| GB9924956D0 (en) * | 1999-10-21 | 1999-12-22 | Pfizer Ltd | Novel polypeptide |
| EP1230361A2 (en) * | 1999-10-27 | 2002-08-14 | PHARMACIA & UPJOHN COMPANY | G protein-coupled receptors expressed in human brain |
| ATE375390T1 (de) * | 1999-10-29 | 2007-10-15 | Pfizer | G-protein-gekoppelter rezeptor-ähnliche proteine |
| WO2001032864A2 (en) * | 1999-11-03 | 2001-05-10 | Merck Patent Gmbh | Gpcr-kd5 polypeptides and dna sequences thereof |
| US6461836B1 (en) * | 1999-11-05 | 2002-10-08 | Smithkline Beecham Corporation | Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof |
| WO2001036473A2 (en) * | 1999-11-16 | 2001-05-25 | Pharmacia & Upjohn Company | Human g protein-coupled receptors |
| US7029857B1 (en) | 1999-12-17 | 2006-04-18 | H. Lundbeck A/S | Processes for obtaining compounds employing SNORF72 receptors |
| WO2001046414A1 (fr) * | 1999-12-20 | 2001-06-28 | Banyu Pharmaceutical Co., Ltd. | Nouvelle proteine receptrice couplee a la proteine de fixation de guanosine triphosphate, bg26 |
| CA2395416A1 (en) | 1999-12-23 | 2001-06-28 | Millennium Pharmaceuticals, Inc. | P2y12 receptor |
| WO2001048189A1 (fr) * | 1999-12-28 | 2001-07-05 | Helix Research Institute | Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers |
| GB0001700D0 (en) * | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Novel protein |
| ATE370411T1 (de) * | 2000-02-04 | 2007-09-15 | Takeda Pharmaceutical | Verfahren zum screening |
| EP1266005B1 (en) * | 2000-03-14 | 2007-03-07 | Bayer HealthCare AG | Regulation of human lipoxin a4 receptor-like protein |
| EP1268777A2 (en) * | 2000-03-17 | 2003-01-02 | Bayer Aktiengesellschaft | Regulation of human leukotriene b 4?-like g protein-coupled receptor |
| AU2001241156A1 (en) * | 2000-03-21 | 2001-10-03 | Yamanouchi Pharmaceutical Co..Ltd. | Novel leukotriene b4 receptor |
| US20030087287A1 (en) * | 2000-03-28 | 2003-05-08 | Masanori Miwa | Novel g-protein-coupled receptor protein and dna thereof |
| AU4467301A (en) * | 2000-03-31 | 2001-10-08 | Helix Research Institute | Novel guanosine triphosphate-binding protein-coupled receptor gprv53, gene thereof and production and use of the same |
| AU2001248755A1 (en) * | 2000-04-12 | 2001-10-23 | Takeda Chemical Industries Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| EP1178110A1 (en) * | 2000-08-01 | 2002-02-06 | Aventis Pharma Deutschland GmbH | EDG8 receptor for sphingosine 1-phosphate , its preparation and use |
| AU6744501A (en) * | 2000-05-18 | 2001-11-26 | Bayer Aktiengesellschaft | Regulation of human dopamine-like g protein-coupled receptor |
| AU2001276837A1 (en) * | 2000-06-23 | 2002-01-08 | Tularik, Inc. | Human and mouse g-protein couipled receptors |
| EP1297139A2 (en) * | 2000-06-26 | 2003-04-02 | Akzo Nobel N.V. | G-protein coupled receptor org10 |
| AU2001281933A1 (en) * | 2000-06-30 | 2002-01-14 | Ingenium Pharmaceuticals Ag | Human g protein-coupled receptor igpcr17, and uses therof |
| US6927041B2 (en) | 2000-07-06 | 2005-08-09 | Bayer Corporation | Human neuropeptide Y-like G protein-coupled receptor |
| AU2001279232A1 (en) * | 2000-08-09 | 2002-02-18 | Millennium Pharmaceuticals, Inc. | Methods for using 14266, a human g protein-coupled receptor |
| US6790608B2 (en) | 2000-09-20 | 2004-09-14 | The Regents Of The University Of California | Methods of identifying and ADP-glucose receptor ligand, agonist or antagonist |
| ATE357457T1 (de) | 2000-11-01 | 2007-04-15 | Astellas Pharma Inc | Verfahren zum screenen eines plättchenhemmers |
| AU1252102A (en) * | 2000-11-07 | 2002-05-21 | Paradigm Therapeutics Ltd | Receptor |
| CA2429860A1 (en) * | 2000-11-27 | 2002-05-30 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human g protein-coupled receptors |
| WO2002044362A1 (en) | 2000-12-01 | 2002-06-06 | Yamanouchi Pharmaceutical Co., Ltd. | Method of screening remedy for diabetes |
| US7220580B2 (en) | 2000-12-22 | 2007-05-22 | University Of South Florida | Sphingosine 1-phosphate receptor gene, sppr |
| AU2002245182A1 (en) * | 2000-12-22 | 2002-07-08 | Mergen Ltd. | Methods for identifying g-protein coupled receptors associated with diseases |
| GB0100782D0 (en) * | 2001-01-11 | 2001-02-21 | Glaxo Group Ltd | Assay |
| EP1382678B1 (en) * | 2001-04-25 | 2008-08-27 | Astellas Pharma Inc. | Guanosine triphosphate-binding protein-coupled recepotr place 6002312 and its gene and production and use of the same |
| US7419658B2 (en) | 2001-07-09 | 2008-09-02 | Euroscreen S.A. | Isolated ligand of ChemerinR |
| US20030096299A1 (en) | 2001-07-09 | 2003-05-22 | Valerie Wittamer | Natural ligand of G protein coupled receptor ChemR23 and uses thereof |
| US7858755B2 (en) | 2001-07-09 | 2010-12-28 | Euroscreen S.A. | Monoclonal antibodies that bind Chemerin polypeptide |
| US6946244B2 (en) | 2001-08-07 | 2005-09-20 | Euroscreen, S.A. | Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13) |
| MXPA04009959A (es) | 2002-04-12 | 2004-12-13 | Schering Corp | Ligandos del receptor acoplado a la proteina g y metodos. |
| WO2004022086A1 (ja) * | 2002-09-02 | 2004-03-18 | Takeda Pharmaceutical Company Limited | 副腎皮質ホルモン分泌調節剤 |
| AU2003271149A1 (en) * | 2002-10-11 | 2004-05-04 | Yamanouchi Pharmaceutical Co., Ltd. | Method of screening remedy for renal failure |
| US7056685B1 (en) | 2002-11-05 | 2006-06-06 | Amgen Inc. | Receptor ligands and methods of modulating receptors |
| US7220734B2 (en) | 2002-12-20 | 2007-05-22 | Merck & Co., Inc. | 1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans, benzothiophenes and indoles as Edg receptor agonists |
| PT1599468E (pt) | 2003-01-14 | 2008-01-14 | Arena Pharm Inc | Derivados de arilo e heteroarilo 1,2,3.-trissubstituídos comomoduladores do metabolismo, e profilaxia e tratamento dedesordens relacionadas tais como diabetes e hiperglicemia |
| US7083933B1 (en) | 2003-05-09 | 2006-08-01 | Prosidion Limited | Methods for identification of modulators of OSGPR116 activity |
| US7524638B1 (en) | 2003-06-27 | 2009-04-28 | Osi Pharmaceuticals, Inc. | Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease |
| CN1812803A (zh) * | 2003-06-27 | 2006-08-02 | 唐纳士公司 | 人类肥大细胞表达的膜蛋白 |
| DOP2006000008A (es) * | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| GB0508990D0 (en) * | 2005-05-03 | 2005-06-08 | Novartis Ag | Organic compounds |
| DK1971862T3 (da) | 2006-04-11 | 2011-02-14 | Arena Pharm Inc | Fremgangsmåder til anvendelse af GPR119-receptor til identificering af forbindelser anvendelige til øgning af knoglemasse hos en person |
| US7638541B2 (en) | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
| CA2693169C (en) | 2007-07-19 | 2016-01-12 | Metabolex, Inc. | N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
| CN101801954B (zh) | 2007-09-20 | 2013-10-09 | Irm责任有限公司 | 作为gpr119活性调节剂的化合物和组合物 |
| EP2146210A1 (en) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY |
| AR077642A1 (es) | 2009-07-09 | 2011-09-14 | Arena Pharm Inc | Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo |
| CA2775840C (en) | 2009-10-01 | 2018-02-06 | Metabolex, Inc. | Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts |
| US8791100B2 (en) | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| MX2012011631A (es) | 2010-04-06 | 2013-01-18 | Arena Pharm Inc | Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con el mismo. |
| ES2676209T3 (es) | 2010-06-23 | 2018-07-17 | Metabolex Inc. | Composiciones de 5-etil-2-{4-[4-(4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina |
| JP5941916B2 (ja) | 2010-09-22 | 2016-06-29 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置 |
| US20140018371A1 (en) | 2011-04-01 | 2014-01-16 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
| WO2012145361A1 (en) | 2011-04-19 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012145604A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012145603A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012170702A1 (en) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2013055910A1 (en) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2014074668A1 (en) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulators of gpr119 and the treatment of disorders related thereto |
| PL3242666T3 (pl) | 2015-01-06 | 2025-02-17 | Arena Pharmaceuticals, Inc. | Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1 |
| DK3310760T3 (da) | 2015-06-22 | 2022-10-24 | Arena Pharm Inc | Krystallinsk L-argininsalt af (R)-2-(7-(4-cyclopentyl-3-(trifluormethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3- yl)eddikesyre til anvendelse ved S1P1-receptor-associerede lidelser |
| EP3493807A1 (en) | 2016-08-03 | 2019-06-12 | CymaBay Therapeutics, Inc. | Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions |
| JP2020524181A (ja) | 2017-06-19 | 2020-08-13 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Ｎａｆｌｄおよびｎａｓｈの治療のための化合物および方法 |
| BR112020024762A2 (pt) | 2018-06-06 | 2021-03-23 | Arena Pharmaceuticals, Inc. | métodos de tratamento de condições relacionadas ao receptor s1p1 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2237937A1 (en) * | 1995-11-15 | 1997-06-05 | Cor Therapeutics, Inc. | Novel purinergic receptor |
| EP0955808A1 (en) * | 1996-01-11 | 1999-11-17 | Human Genome Sciences, Inc. | Human g-protein coupled receptor |
| WO1998031810A2 (en) * | 1997-01-21 | 1998-07-23 | Schering Corporation | Mammalian chemokines; receptors; reagents; uses |
| US6221627B1 (en) * | 1997-02-24 | 2001-04-24 | Smithkline Beecham Corporation | cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor |
| US5955303A (en) * | 1997-03-06 | 1999-09-21 | Incyte Pharmaceuticals, Inc. | Human chemokine receptor-like protein |
| US6555339B1 (en) * | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| US6060272A (en) * | 1997-05-07 | 2000-05-09 | Human Genome Sciences, Inc. | Human G-protein coupled receptors |
| EP0899332A3 (en) * | 1997-08-15 | 2000-07-05 | Smithkline Beecham Corporation | The G-protein coupled receptor HFIAO41 |
| CA2239255A1 (en) * | 1997-10-23 | 1999-04-23 | Smithkline Beecham Corporation | Cdna clone hneaa81 that encodes a human 7-transmembrane receptor |
| US5932445A (en) * | 1997-11-07 | 1999-08-03 | Incyte Pharmaceuticals, Inc. | Signal peptide-containing proteins |
| ATE362983T1 (de) * | 1997-11-11 | 2007-06-15 | Ono Pharmaceutical Co | Menschlicher lysophosphatidsäure rezeptor und dessen verwendung |
| US6207412B1 (en) * | 1997-11-13 | 2001-03-27 | The Regents Of The University Of California | Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells |
| JP2002504492A (ja) * | 1998-02-20 | 2002-02-12 | スミスクライン ビーチャム コーポレーション | Ｇタンパク質共役型受容体Ｆｉｓｈｂｏｙ |
| EP1067183B1 (en) * | 1998-03-12 | 2006-05-17 | Astellas Pharma Inc. | Novel g protein-coupled receptor proteins |
| AU3749499A (en) * | 1998-04-16 | 1999-11-01 | Millenium Pharmaceuticals, Inc. | Novel molecules of the bgckr-related protein family and uses thereof |
| WO1999055733A1 (en) * | 1998-04-24 | 1999-11-04 | Smithkline Beecham Corporation | Cloning of a novel 7tm receptor axor-2 |
| SE9801455D0 (sv) * | 1998-04-24 | 1998-04-24 | Astra Pharma Inc | New receptor |
| US6071722A (en) * | 1998-04-24 | 2000-06-06 | Smithkline Beecham Corporation | Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1) |
| CA2340334A1 (en) * | 1998-08-19 | 2000-03-02 | Millenium Pharmaceuticals, Inc. | 14274 receptor, a g-protein coupled receptor related to the edg receptor family |
| WO2000011170A1 (en) * | 1998-08-20 | 2000-03-02 | Millennium Pharmaceuticals, Inc. | 14400 receptor, a g-protein coupled receptor |
| EP1107978A1 (en) * | 1998-08-24 | 2001-06-20 | Alphagene, Inc. | Secreted proteins and polynucleotides encoding them |
| AU5801099A (en) * | 1998-09-02 | 2000-03-21 | Millennium Pharmaceuticals, Inc. | 14926 receptor, a novel g-protein coupled receptor |
| IL142153A0 (en) * | 1998-10-13 | 2002-03-10 | Arena Pharm Inc | Non-endogenous, constitutively activated human g protein-coupled receptors |
| EP1123397A2 (en) * | 1998-10-16 | 2001-08-16 | Millennium Pharmaceuticals, Inc. | G-protein coupled receptors |
| CA2349759A1 (en) * | 1998-11-04 | 2000-05-11 | Chiron Corporation | Isolated vshk-1 receptor polypeptides and methods of use thereof |
| EP1127126B1 (en) * | 1998-11-06 | 2006-10-18 | Bayer HealthCare AG | G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof |
| US6221660B1 (en) * | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| US6689866B1 (en) * | 1999-03-09 | 2004-02-10 | Curagen Corporation | Polynucleotides and proteins encoded thereby |
| GB9923177D0 (en) * | 1999-09-30 | 1999-12-01 | Pfizer Ltd | Novel polypeptide |
| US6590938B1 (en) * | 1999-09-30 | 2003-07-08 | Conexant Systems, Inc. | DCT domain conversion of a higher definition signal to lower definition signal |
-
1999
- 1999-10-13 EP EP99972682A patent/EP1133559B1/en not_active Expired - Lifetime
- 1999-10-13 AT AT99972682T patent/ATE301673T1/de active
- 1999-10-13 ES ES99972682T patent/ES2243095T3/es not_active Expired - Lifetime
- 1999-10-13 IL IL14253899A patent/IL142538A0/xx unknown
- 1999-10-13 PT PT99972682T patent/PT1133559E/pt unknown
- 1999-10-13 ES ES05003040T patent/ES2289610T3/es not_active Expired - Lifetime
- 1999-10-13 PT PT07008841T patent/PT1849866E/pt unknown
- 1999-10-13 DK DK05003040T patent/DK1584683T3/da active
- 1999-10-13 JP JP2000584067A patent/JP2003534767A/ja not_active Withdrawn
- 1999-10-13 AT AT07008841T patent/ATE396400T1/de active
- 1999-10-13 AU AU37904/00A patent/AU770056B2/en not_active Ceased
- 1999-10-13 NZ NZ537625A patent/NZ537625A/en not_active IP Right Cessation
- 1999-10-13 PT PT05003040T patent/PT1584683E/pt unknown
- 1999-10-13 KR KR1020017006279A patent/KR100765039B1/ko not_active Expired - Fee Related
- 1999-10-13 EP EP10010658A patent/EP2295574A1/en not_active Withdrawn
- 1999-10-13 EP EP07001452A patent/EP1780280A1/en not_active Ceased
- 1999-10-13 AT AT05003040T patent/ATE366815T1/de active
- 1999-10-13 NZ NZ511087A patent/NZ511087A/en not_active IP Right Cessation
- 1999-10-13 KR KR1020087024998A patent/KR20080104062A/ko not_active Withdrawn
- 1999-10-13 EP EP05003040A patent/EP1584683B1/en not_active Expired - Lifetime
- 1999-10-13 EP EP10008862A patent/EP2295572A1/en not_active Withdrawn
- 1999-10-13 KR KR1020087003575A patent/KR100926209B1/ko not_active Expired - Fee Related
- 1999-10-13 CA CA002645717A patent/CA2645717A1/en not_active Withdrawn
- 1999-10-13 KR KR1020077018185A patent/KR100926208B1/ko not_active Expired - Fee Related
- 1999-10-13 WO PCT/US1999/023687 patent/WO2000031258A2/en not_active Ceased
- 1999-10-13 ES ES07008841T patent/ES2308759T3/es not_active Expired - Lifetime
- 1999-10-13 KR KR1020087003578A patent/KR100963367B1/ko not_active Expired - Fee Related
- 1999-10-13 EP EP10010303A patent/EP2295573A1/en not_active Withdrawn
- 1999-10-13 EP EP07008841A patent/EP1849866B1/en not_active Expired - Lifetime
- 1999-10-13 EP EP05005946A patent/EP1580271A3/en not_active Ceased
- 1999-10-13 CA CA002348377A patent/CA2348377C/en not_active Expired - Fee Related
- 1999-10-13 NZ NZ527622A patent/NZ527622A/en not_active IP Right Cessation
- 1999-10-13 DK DK07008841T patent/DK1849866T3/da active
- 1999-10-13 DK DK99972682T patent/DK1133559T3/da active
-
2001
- 2001-04-11 IL IL142538A patent/IL142538A/en not_active IP Right Cessation
-
2004
- 2004-04-28 JP JP2004132989A patent/JP2004267216A/ja not_active Withdrawn
- 2004-05-12 AU AU2004202147A patent/AU2004202147A1/en not_active Abandoned
-
2007
- 2007-05-15 JP JP2007129923A patent/JP2007209352A/ja active Pending
-
2008
- 2008-02-14 JP JP2008033839A patent/JP2008133300A/ja active Pending
-
2009
- 2009-07-03 JP JP2009159339A patent/JP2009298791A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004267216A5 (OSRAM) | ||
| Guo et al. | Identification of a novel lineage bat SARS-related coronaviruses that use bat ACE2 receptor | |
| KR102483242B1 (ko) | Mg53 돌연변이체, 및 그의 제조 방법 및 그의 용도 | |
| JP2005052158A5 (OSRAM) | ||
| JP7427208B2 (ja) | 視覚機能再生剤又は視覚機能低下予防剤 | |
| JP2011509093A5 (OSRAM) | ||
| JP2003530124A5 (OSRAM) | ||
| JPH03155795A (ja) | マウス・インターロイキン―６レセプター蛋白質 | |
| Yang et al. | Molecular basis of transferrin polymorphism in goldfish (Carassius auratus) | |
| JP2003530821A5 (OSRAM) | ||
| Jaso-Friedmann et al. | The antigen receptor (NCCRP-1) on catfish and zebrafish nonspecific cytotoxic cells belongs to a new gene family characterized by an F-box-associated domain | |
| JP2020127419A5 (OSRAM) | ||
| JP2004537284A5 (OSRAM) | ||
| JP2013502217A5 (OSRAM) | ||
| WO2000077211A1 (en) | Pyrexia-associated genes and pyrexia-associated proteins of plant | |
| JP2003514549A5 (OSRAM) | ||
| JP2005507651A5 (OSRAM) | ||
| JP2005507245A5 (OSRAM) | ||
| RU2007111137A (ru) | Гонадотропный гормон, полученный из беспозвоночных, и его синтез | |
| Suter et al. | Cloning of the cDNA encoding the porcine p55 tumor necrosis factor receptor | |
| JP2003525018A5 (OSRAM) | ||
| Rashid et al. | Isolation of growth hormone gene from the Malaysian mahseer, Tor tambroides | |
| CN102250930B (zh) | 家蚕蜕皮激素氧化酶eo基因 | |
| JP2005218447A5 (OSRAM) | ||
| Roovers et al. | Insulin-Related Peptides and Their Receptor (s) in the Mollusc, Lymnaea Stagnalis |