JP2003526786A5 - - Google Patents
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- Publication number
- JP2003526786A5 JP2003526786A5 JP2001566027A JP2001566027A JP2003526786A5 JP 2003526786 A5 JP2003526786 A5 JP 2003526786A5 JP 2001566027 A JP2001566027 A JP 2001566027A JP 2001566027 A JP2001566027 A JP 2001566027A JP 2003526786 A5 JP2003526786 A5 JP 2003526786A5
- Authority
- JP
- Japan
- Prior art keywords
- carrier
- polysaccharide
- functional group
- layer
- analyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000004676 glycans Chemical class 0.000 description 26
- 229920001282 polysaccharide Polymers 0.000 description 26
- 239000005017 polysaccharide Substances 0.000 description 26
- 125000000524 functional group Chemical group 0.000 description 17
- 239000010410 layer Substances 0.000 description 16
- 239000012491 analyte Substances 0.000 description 13
- 238000000034 method Methods 0.000 description 9
- 239000011247 coating layer Substances 0.000 description 8
- 230000009870 specific binding Effects 0.000 description 8
- 229920002307 Dextran Polymers 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000004451 qualitative analysis Methods 0.000 description 3
- 238000004445 quantitative analysis Methods 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- 108091034117 Oligonucleotide Proteins 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 230000027455 binding Effects 0.000 description 2
- 150000001718 carbodiimides Chemical class 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 230000021615 conjugation Effects 0.000 description 2
- 108090001008 Avidin Proteins 0.000 description 1
- 102000014914 Carrier Proteins Human genes 0.000 description 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 1
- 102000004856 Lectins Human genes 0.000 description 1
- 108090001090 Lectins Proteins 0.000 description 1
- 108010090804 Streptavidin Proteins 0.000 description 1
- 125000003172 aldehyde group Chemical group 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 108091008324 binding proteins Proteins 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000005081 chemiluminescent agent Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 102000028557 immunoglobulin binding proteins Human genes 0.000 description 1
- 108091009323 immunoglobulin binding proteins Proteins 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000002523 lectin Substances 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 239000006249 magnetic particle Substances 0.000 description 1
- 125000005439 maleimidyl group Chemical group C1(C=CC(N1*)=O)=O 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/005978 WO2001067105A1 (en) | 2000-03-06 | 2000-03-06 | Carriers coated with polysaccharides, their preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003526786A JP2003526786A (ja) | 2003-09-09 |
| JP2003526786A5 true JP2003526786A5 (https=) | 2007-04-19 |
| JP4448642B2 JP4448642B2 (ja) | 2010-04-14 |
Family
ID=21741129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001566027A Expired - Lifetime JP4448642B2 (ja) | 2000-03-06 | 2000-03-06 | 多糖で被覆された担体、その製造および使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7179660B1 (https=) |
| EP (1) | EP1264181B1 (https=) |
| JP (1) | JP4448642B2 (https=) |
| CA (1) | CA2400993C (https=) |
| DE (1) | DE60035127T2 (https=) |
| ES (1) | ES2287006T3 (https=) |
| WO (1) | WO2001067105A1 (https=) |
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| US20060040258A1 (en) * | 2004-08-23 | 2006-02-23 | Huiyan Guo | Water-soluble conjugates and methods of preparation |
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| JP4873123B2 (ja) * | 2005-11-28 | 2012-02-08 | Ｊｓｒ株式会社 | 担体ポリマー粒子の製造方法 |
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| BR112015032134B1 (pt) * | 2013-06-24 | 2022-05-10 | Exthera Medical Corporation | Método de ligação em ponto de extremidade de uma manose não redutora a um substrato e esfera possuindo uma manose ligada em ponto de extremidade |
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| US6231982B1 (en) | 1997-12-10 | 2001-05-15 | Dade Behring Inc. | Particle reagents having reduced matrix effects and containing an aldehyde-reactive functional group |
-
2000
- 2000-03-06 US US10/220,623 patent/US7179660B1/en not_active Expired - Lifetime
- 2000-03-06 CA CA2400993A patent/CA2400993C/en not_active Expired - Lifetime
- 2000-03-06 WO PCT/US2000/005978 patent/WO2001067105A1/en not_active Ceased
- 2000-03-06 EP EP00919371A patent/EP1264181B1/en not_active Expired - Lifetime
- 2000-03-06 JP JP2001566027A patent/JP4448642B2/ja not_active Expired - Lifetime
- 2000-03-06 ES ES00919371T patent/ES2287006T3/es not_active Expired - Lifetime
- 2000-03-06 DE DE60035127T patent/DE60035127T2/de not_active Expired - Lifetime
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