JP2003518091A5 - - Google Patents

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Publication number
JP2003518091A5
JP2003518091A5 JP2001547048A JP2001547048A JP2003518091A5 JP 2003518091 A5 JP2003518091 A5 JP 2003518091A5 JP 2001547048 A JP2001547048 A JP 2001547048A JP 2001547048 A JP2001547048 A JP 2001547048A JP 2003518091 A5 JP2003518091 A5 JP 2003518091A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001547048A
Other languages
Japanese (ja)
Other versions
JP3742593B2 (ja
JP2003518091A (ja
Filing date
Publication date
Priority claimed from GBGB9930318.2A external-priority patent/GB9930318D0/en
Application filed filed Critical
Publication of JP2003518091A publication Critical patent/JP2003518091A/ja
Publication of JP2003518091A5 publication Critical patent/JP2003518091A5/ja
Application granted granted Critical
Publication of JP3742593B2 publication Critical patent/JP3742593B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2001547048A 1999-12-22 2000-12-18 ファルネシルトランスフェラーゼ阻害剤 Expired - Fee Related JP3742593B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9930318.2A GB9930318D0 (en) 1999-12-22 1999-12-22 Novel compounds
GB9930318.2 1999-12-22
PCT/GB2000/004856 WO2001046137A1 (en) 1999-12-22 2000-12-18 Farnesyl transferase inhibitors

Publications (3)

Publication Number Publication Date
JP2003518091A JP2003518091A (ja) 2003-06-03
JP2003518091A5 true JP2003518091A5 (enExample) 2005-12-22
JP3742593B2 JP3742593B2 (ja) 2006-02-08

Family

ID=10866834

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001547048A Expired - Fee Related JP3742593B2 (ja) 1999-12-22 2000-12-18 ファルネシルトランスフェラーゼ阻害剤

Country Status (27)

Country Link
US (1) US7101897B2 (enExample)
EP (1) EP1255733B1 (enExample)
JP (1) JP3742593B2 (enExample)
KR (1) KR20020063251A (enExample)
CN (2) CN1229344C (enExample)
AR (1) AR029460A1 (enExample)
AT (1) ATE316074T1 (enExample)
AU (1) AU776003B2 (enExample)
BR (1) BR0016669A (enExample)
CA (1) CA2387579A1 (enExample)
CO (1) CO5360641A1 (enExample)
CZ (1) CZ20022125A3 (enExample)
DE (1) DE60025650D1 (enExample)
EE (1) EE200200206A (enExample)
GB (1) GB9930318D0 (enExample)
HU (1) HUP0204135A3 (enExample)
IL (1) IL149871A0 (enExample)
IS (1) IS6358A (enExample)
MX (1) MXPA02005981A (enExample)
MY (1) MY133606A (enExample)
NO (1) NO20022924L (enExample)
NZ (1) NZ518341A (enExample)
PL (1) PL355887A1 (enExample)
RU (1) RU2259997C2 (enExample)
SK (1) SK8642002A3 (enExample)
WO (1) WO2001046137A1 (enExample)
ZA (1) ZA200202694B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005117864A1 (en) * 2004-05-28 2005-12-15 Astrazeneca Ab Combination product comprising anastrozole and a dual prenyl transferase inhibitor
WO2006038719A1 (ja) * 2004-10-08 2006-04-13 Kotobuki Pharmaceutical Co., Ltd. ホスホン酸誘導体及び血中の高リン酸が関与する疾患の治療剤
US20110136867A1 (en) * 2006-02-02 2011-06-09 Justman Craig J Treatment of Synucleinopathies
WO2009151683A2 (en) 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
WO2010057006A1 (en) 2008-11-13 2010-05-20 Link Medicine Corporation Azaquinolinone derivatives and uses thereof
US8975247B2 (en) 2009-03-18 2015-03-10 The Board Of Trustees Of The Leland Stanford Junion University Methods and compositions of treating a flaviviridae family viral infection
WO2011088126A2 (en) * 2010-01-13 2011-07-21 Eiger Biopharmaceuticals, Inc. Treatment of viral infection with prenyltransferase inhibitors

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU422723A1 (ru) * 1972-03-29 1974-04-05 Б. В. Салов, Т. А. Губенкова , И. В. Быховска Способ получения 5-нитро-2-аминобензойнойкислоты
CA1283906C (en) 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS60233076A (ja) 1984-05-03 1985-11-19 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
EP0182213B1 (en) 1984-11-08 1990-09-26 Sumitomo Pharmaceuticals Company, Limited Carbapenem compounds and production thereof
KR880006244A (ko) 1986-11-24 1988-07-22 후지사와 도모 기찌 로 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법
GB8921635D0 (en) 1989-09-25 1989-11-08 Fujisawa Pharmaceutical Co 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives
CA2036163C (en) 1990-02-14 2001-06-19 Makoto Sunagawa Novel beta-lactam compounds and their production
FI96863C (fi) 1990-02-23 1996-09-10 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten /2-(1-homopiperatsiinikarbonyyli)pyrrolidin-4-yylitio/-6-(1-hydroksietyyli)-1-karbapen-2-eemi-3-karboksylaattisuolojen valmistamiseksi
GB9107363D0 (en) 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
US6083917A (en) 1990-04-18 2000-07-04 Board Of Regents, The University Of Texas System Methods and compositions for the identification, characterization and inhibition of farnesyltransferase
US5185248A (en) 1990-05-08 1993-02-09 E. R. Squibb & Sons, Inc. Farnesyl-protein transferase assay for identifying compounds that block neoplastic transformation
JPH0578360A (ja) 1991-01-31 1993-03-30 Banyu Pharmaceut Co Ltd 2−[2−(スルフアモイルアルキル)ピロリジニルチオカルバペネム誘導体
GB9107341D0 (en) 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
GB9107342D0 (en) 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
AU651887B2 (en) 1991-06-04 1994-08-04 Sankyo Company Limited 1-methylcarbapenem derivatives, their preparation and their use as antibiotics
JPH04368386A (ja) 1991-06-18 1992-12-21 Sankyo Co Ltd 1−メチルカルバペネム−3−カルボン酸の製造法
US5360798A (en) 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
DE69204007T2 (de) 1991-10-11 1996-03-21 Squibb & Sons Inc Verwendung von Farnesyl-Protein Transferaseinhibitoren zur Herstellung eines Arzneimittels zur Blockierung von durch Ras-Oncogenen hervorgerufenen neoplastischen Transformationen von Zellen.
JPH05239058A (ja) 1991-12-17 1993-09-17 Fujisawa Pharmaceut Co Ltd 3−ピロリジニルチオ−1−アザビシクロ[3.2.0ヘプト−2−エン−2−カルボン酸化合物
GB9202298D0 (en) 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
CZ290002B6 (cs) 1992-03-11 2002-05-15 Sankyo Company Limited Antimikrobiální karbapenemové deriváty, způsob výroby a farmaceutický prostředek
GB9304156D0 (en) 1992-03-26 1993-04-21 Zeneca Ltd Antibiotic compounds
CA2091309A1 (en) 1992-03-26 1993-09-27 Frederic H. Jung Antibiotic compounds
JP3367104B2 (ja) 1992-04-13 2003-01-14 藤沢薬品工業株式会社 抗菌剤としての置換された3−ピロリジニルチオ−カルバペネム化合物
EP0581501B1 (en) 1992-07-21 1998-09-09 Zeneca Limited Antibiotic carbapenem compounds
EP0581502B1 (en) 1992-07-21 1998-10-21 Zeneca Limited Antibiotic carbapenem compounds
CA2099818A1 (en) 1992-07-21 1994-01-22 Frederic H. Jung Antibiotic compounds
EP0590885B1 (en) 1992-09-28 2000-03-15 Zeneca Limited Antibiotic carbapenem compounds
CA2106330A1 (en) 1992-10-07 1994-04-08 Patrice J. Siret Antibiotic compounds
CA2118985A1 (en) 1993-04-02 1994-10-03 Dinesh V. Patel Heterocyclic inhibitors of farnesyl protein transferase
CA2165176A1 (en) 1993-06-18 1995-01-05 Samuel L. Graham Inhibitors of farnesyl-protein transferase
JP2534823B2 (ja) 1993-07-07 1996-09-18 日本電気株式会社 印刷装置
US5468733A (en) 1993-09-30 1995-11-21 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP0725650A4 (en) 1993-09-30 1999-02-03 Merck & Co Inc INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
CA2155448A1 (en) 1994-08-11 1996-02-12 Katerina Leftheris Inhibitors of farnesyl protein transferase
US5571835A (en) 1994-09-29 1996-11-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP0817630A4 (en) 1995-03-29 1999-01-27 Merck & Co Inc INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
BR9609744A (pt) 1995-07-31 1999-03-02 Shionogi & Co Derivados de pirrolidina tendo atividade inibitória de fosfolipase a2
GB9515975D0 (en) 1995-08-04 1995-10-04 Zeneca Ltd Chemical compounds
NO307879B1 (no) * 1995-09-18 2000-06-13 Sankyo Co Nye ureaderivater med ACAT-inhiberende aktivitet og farmasøytisk preparat inneholdende disse
JPH1050029A (ja) 1996-05-28 1998-02-20 Nobuyuki Higuchi 情報記憶装置
WO1998007692A1 (en) * 1996-08-17 1998-02-26 Zeneca Limited 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors
US6414145B1 (en) 1997-01-29 2002-07-02 Zeneca Limited Imidazolyl compounds as inhibitors of farnesyl-protein tranferase
AR015649A1 (es) 1997-05-07 2001-05-16 Univ Pittsburgh Inhibidores de isoprenil-transferasas proteicas, composiciones que los comprenden y el uso de los mismos para la fabricacion de un medicamento
WO1999041235A1 (en) * 1998-02-10 1999-08-19 Astrazeneca Uk Limited Farnesyl transferase inhibitors

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