JP2003515526A5 - - Google Patents
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- JP2003515526A5 JP2003515526A5 JP2001516885A JP2001516885A JP2003515526A5 JP 2003515526 A5 JP2003515526 A5 JP 2003515526A5 JP 2001516885 A JP2001516885 A JP 2001516885A JP 2001516885 A JP2001516885 A JP 2001516885A JP 2003515526 A5 JP2003515526 A5 JP 2003515526A5
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- Prior art keywords
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- acid
- compound
- nitroxy
- Prior art date
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- 150000001875 compounds Chemical class 0.000 description 4
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 description 2
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 2
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 description 1
- SJZRECIVHVDYJC-UHFFFAOYSA-N 4-hydroxybutyric acid Chemical compound OCCCC(O)=O SJZRECIVHVDYJC-UHFFFAOYSA-N 0.000 description 1
- 229940006015 4-hydroxybutyric acid Drugs 0.000 description 1
- ZETOHPSSBWBMED-UHFFFAOYSA-N 4-nitrooxybutanoic acid Chemical compound OC(=O)CCCO[N+]([O-])=O ZETOHPSSBWBMED-UHFFFAOYSA-N 0.000 description 1
- IWHLYPDWHHPVAA-UHFFFAOYSA-N 6-hydroxyhexanoic acid Chemical compound OCCCCCC(O)=O IWHLYPDWHHPVAA-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- OGSPWJRAVKPPFI-UHFFFAOYSA-N Alendronic Acid Chemical compound NCCCC(O)(P(O)(O)=O)P(O)(O)=O OGSPWJRAVKPPFI-UHFFFAOYSA-N 0.000 description 1
- 0 C**N(C=NC12)C1=CC(*=C)NC2=O Chemical compound C**N(C=NC12)C1=CC(*=C)NC2=O 0.000 description 1
- 206010048554 Endothelial dysfunction Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 description 1
- 229960004150 aciclovir Drugs 0.000 description 1
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 1
- 229960004343 alendronic acid Drugs 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 description 1
- 229960005174 ambroxol Drugs 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229960004679 doxorubicin Drugs 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000008694 endothelial dysfunction Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 description 1
- 229940114124 ferulic acid Drugs 0.000 description 1
- 235000001785 ferulic acid Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 125000006216 methylsulfinyl group Chemical group [H]C([H])([H])S(*)=O 0.000 description 1
- 210000004798 organs belonging to the digestive system Anatomy 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 229960003712 propranolol Drugs 0.000 description 1
- 229960002052 salbutamol Drugs 0.000 description 1
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 description 1
- 229960000894 sulindac Drugs 0.000 description 1
- YLJREFDVOIBQDA-UHFFFAOYSA-N tacrine Chemical compound C1=CC=C2C(N)=C(CCCC3)C3=NC2=C1 YLJREFDVOIBQDA-UHFFFAOYSA-N 0.000 description 1
- 229960001685 tacrine Drugs 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- 210000002229 urogenital system Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI001817A IT1314184B1 (it) | 1999-08-12 | 1999-08-12 | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
| IT99A001817 | 1999-08-12 | ||
| PCT/EP2000/007225 WO2001012584A2 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003515526A JP2003515526A (ja) | 2003-05-07 |
| JP2003515526A5 true JP2003515526A5 (enExample) | 2009-11-19 |
Family
ID=11383554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001516885A Ceased JP2003515526A (ja) | 1999-08-12 | 2000-07-27 | 医薬化合物 |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US7186753B1 (enExample) |
| EP (2) | EP1593664A1 (enExample) |
| JP (1) | JP2003515526A (enExample) |
| KR (2) | KR100760394B1 (enExample) |
| CN (2) | CN100528834C (enExample) |
| AT (1) | ATE297375T1 (enExample) |
| AU (1) | AU781643B2 (enExample) |
| BR (1) | BR0013264A (enExample) |
| CA (2) | CA2381409A1 (enExample) |
| DE (1) | DE60020741T2 (enExample) |
| DK (1) | DK1252133T3 (enExample) |
| ES (1) | ES2243292T3 (enExample) |
| HU (1) | HUP0203939A3 (enExample) |
| IL (1) | IL147801A0 (enExample) |
| IT (1) | IT1314184B1 (enExample) |
| MX (1) | MXPA02001519A (enExample) |
| NO (2) | NO328498B1 (enExample) |
| NZ (2) | NZ516889A (enExample) |
| PL (1) | PL203200B1 (enExample) |
| PT (1) | PT1252133E (enExample) |
| RU (1) | RU2264383C2 (enExample) |
| WO (1) | WO2001012584A2 (enExample) |
| ZA (1) | ZA200200628B (enExample) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824669A (en) | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| US20050137191A1 (en) * | 1996-06-04 | 2005-06-23 | Thatcher Gregory R. | Nitrate esters and their use for mitigating cellular damage |
| IT1288123B1 (it) | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
| US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
| IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
| JP2003523958A (ja) | 1999-12-23 | 2003-08-12 | ニトロメド インコーポレーテッド | ニトロソ化およびニトロシル化されたシクロオキシゲナーゼ−２の阻害剤、組成物ならびに使用法 |
| IT1317735B1 (it) * | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
| CA2410632A1 (en) | 2000-06-22 | 2001-12-27 | David S. Garvey | Nitrosated and nitrosylated taxanes, compositions and methods of use |
| IT1319202B1 (it) * | 2000-10-12 | 2003-09-26 | Nicox Sa | Farmaci per le malattie a base infiammatoria. |
| CA2432642A1 (en) | 2000-12-21 | 2002-08-08 | Subhash P. Khanapure | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| AU2008201838B2 (en) * | 2001-05-02 | 2010-07-29 | Nicox S.A. | Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use |
| ATE437637T1 (de) | 2001-05-02 | 2009-08-15 | Nitromed Inc | Nitrosiertes und nitrosyliertes nebivolol und seine metaboliten, zusammensetzungen und anwendungsverfahren |
| GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| SE0101702D0 (sv) | 2001-05-15 | 2001-05-15 | Ardenia Investments Ltd | Novel potentiating compounds |
| ITMI20011307A1 (it) * | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per l'epilessia |
| ITMI20011308A1 (it) | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per il dolore cronico |
| ITMI20011744A1 (it) * | 2001-08-09 | 2003-02-09 | Nicox Sa | Farmaci per le vasculopatie |
| EP2319518A1 (en) | 2002-02-04 | 2011-05-11 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Use of CO-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases |
| EP1497268A4 (en) * | 2002-04-05 | 2006-01-18 | Nitromed Inc | NITROGEN OXIDE DISPENSER, COMPOSITIONS AND METHOD OF USE |
| US7288535B2 (en) | 2002-05-02 | 2007-10-30 | Osteoscreen, Inc. | Methods and compositions for stimulating bone growth using nitric oxide releasing bisphosphonate conjugates |
| US7220749B2 (en) | 2002-06-11 | 2007-05-22 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| JP2005535642A (ja) | 2002-06-28 | 2005-11-24 | ニトロメッド インコーポレーティッド | オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法 |
| JP2005539089A (ja) * | 2002-07-03 | 2005-12-22 | ニトロメッド インコーポレーティッド | ニトロソ化非ステロイド性抗炎症化合物、組成物および使用方法 |
| CA2493156A1 (en) | 2002-07-29 | 2004-02-05 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| AU2003254282A1 (en) | 2002-08-01 | 2004-02-23 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
| ITMI20021861A1 (it) * | 2002-08-29 | 2004-02-29 | Nicox Sa | Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione. |
| ITMI20022658A1 (it) | 2002-12-17 | 2004-06-18 | Nicox Sa | Farmaci per il dolore cronico. |
| US7166638B2 (en) | 2003-05-27 | 2007-01-23 | Nicox S.A. | Statin derivatives |
| US7169805B2 (en) | 2003-05-28 | 2007-01-30 | Nicox S.A. | Captopril derivatives |
| WO2004110432A1 (en) | 2003-06-19 | 2004-12-23 | Nicox S.A. | Enalapril-nitroxyderivatives derivatives and related compounds as ace inhibitors for the treatment of cardiovascular diseases |
| JP2007502831A (ja) * | 2003-08-20 | 2007-02-15 | ニトロメッド インコーポレーティッド | ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法 |
| ATE399757T1 (de) | 2003-11-20 | 2008-07-15 | Nicox Sa | Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol |
| JP2007513113A (ja) * | 2003-12-02 | 2007-05-24 | ニコックス エス エイ | 抗高血圧薬剤のニトロオキシ誘導体 |
| DK1691804T3 (da) * | 2003-12-02 | 2007-07-16 | Nicox Sa | Nitrooxydderivater af carvedilol og andre beta-blokkere som antihypertensive lægemidler |
| US20090131342A1 (en) * | 2004-01-22 | 2009-05-21 | Nitromed, Inc. | Nitrosated and/or nitrosylated compounds, compositions and methods of use |
| KR100503443B1 (ko) * | 2004-02-02 | 2005-07-22 | 한림제약(주) | 광학적으로 활성인 세티리진 또는 그의 염의 제조방법 |
| WO2006008196A1 (en) | 2004-07-20 | 2006-01-26 | Nicox S.A. | Process for preparing nitrooxy esters, nitrooxy thioesters, nitrooxy carbonates and nitrooxy thiocarbonates, intermediates useful in said process and preparation thereof |
| AU2005281359A1 (en) | 2004-08-26 | 2006-03-16 | Apparao Satyam | Prodrugs and codrugs containing novel bio-cleavable disulfide linkers |
| TW200616604A (en) | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
| KR101450653B1 (ko) * | 2006-07-18 | 2014-10-14 | 안티브 홀딩스 인크. | 비스테로이드 항염증제의 황화수소 유도체 |
| TW200831079A (en) * | 2006-12-13 | 2008-08-01 | Merck & Co Inc | Angiotensin II receptor antagonists |
| RU2340597C1 (ru) * | 2007-03-21 | 2008-12-10 | Институт физиологически активных веществ Российской Академии наук | Нитроксиалкиламинокислоты |
| US20080317673A1 (en) * | 2007-06-20 | 2008-12-25 | Fatema Salem Al-Thallab | Method for diagnosing and treating bronchial asthma |
| US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
| WO2009007230A1 (en) | 2007-07-09 | 2009-01-15 | Nicox S.A. | Use of nitric oxide releasing compounds in the treatment of chronic pain |
| EP2188245B1 (en) | 2007-08-17 | 2013-11-06 | Council of Scientific & Industrial Research | Nitric oxide releasing derivatives of paracetamol |
| US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
| EP3090739A1 (en) | 2008-01-04 | 2016-11-09 | Schabar Research Associates LLC | Compositions composed of naproxen sodium and nizatidine |
| RU2364394C1 (ru) * | 2008-03-19 | 2009-08-20 | Михаил Владимирович Покровский | Способ коррекции эндотелиальной дисфункции клопидогрелем при l-name индуцированном дефиците оксида азота |
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| MD4009C2 (ro) * | 2008-07-15 | 2010-08-31 | Институт Химии Академии Наук Молдовы | Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos |
| HRP20140929T1 (hr) | 2008-08-01 | 2014-12-05 | Onconox Aps | Antitumorska svojstva no-modificiranih inhibitora proteaze |
| WO2010108843A1 (en) | 2009-03-27 | 2010-09-30 | Nicox S.A. | Use of nitrooxyderivative of paracetamol for the treatment of muscular dystrophies |
| FR2953145B1 (fr) * | 2009-11-30 | 2013-07-19 | Inst Francais Du Petrole | Solution absorbante contenant un inhibiteur de degradation derive de la pyrimidine ou de la triazine et procede d'absorption de composes acides contenus dans un effluent gazeux |
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| JO3350B1 (ar) | 2011-03-07 | 2019-03-13 | Merck Sharp & Dohme | مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات |
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| CN102557967A (zh) * | 2011-12-28 | 2012-07-11 | 合肥科尚医药科技有限公司 | 一种盐酸氨溴索的制备方法 |
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| US10881654B2 (en) | 2015-04-24 | 2021-01-05 | University Of Louisville Research Foundation, Inc. | Selective PFKFB4 inhibitors for the treatment of cancer |
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| CA3073952A1 (en) | 2017-08-31 | 2019-03-07 | University Of Louisville Research Foundation, Inc. | Quinoline derivative, compositions comprising this compound and uses thereof in the treatment of cancer |
| US10774046B2 (en) | 2017-10-26 | 2020-09-15 | University Of Louisville Research Foundation, Inc. | Inhibitors for the treatment of cancer and related methods |
| RU2709067C1 (ru) * | 2018-07-23 | 2019-12-13 | федеральное государственное бюджетное образовательное учреждение высшего образования "Тольяттинский государственный университет" | Способ термосиловой обработки длинномерных осесимметричных деталей и устройство для его осуществления |
| US12514846B2 (en) | 2020-07-15 | 2026-01-06 | Schabar Research Associates Llc | Unit oral dose compositions composed of ibuprofen or a pharmaceutically acceptable salt thereof and famotidine or a pharmaceutically acceptable salt thereof for the treatment of acute pain and the reduction of the severity and/or risk of heartburn and/or upset stomach |
| US11324727B2 (en) | 2020-07-15 | 2022-05-10 | Schabar Research Associates, Llc | Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn |
| JP2023534810A (ja) | 2020-07-15 | 2023-08-14 | シャバー リサーチ アソシエイツ エルエルシー | 急性痛の処置並びに胸やけの重症度及び／又はリスクの低減のための、イブプロフェン及びファモチジンから構成される単位経口用量組成物 |
| CN112316158B (zh) * | 2020-11-19 | 2021-09-21 | 四川大学 | 一种利用超分子包合剂关闭胶原溶液中抗菌剂活性的方法 |
| CN116270562B (zh) * | 2022-03-18 | 2025-07-01 | 北京诺和德美医药科技有限公司 | 一种制备稳定的吸入用2-氨基-3,5-二溴苯甲胺衍生物溶液的方法 |
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| DE2805404A1 (de) * | 1978-02-09 | 1979-08-16 | Merck Patent Gmbh | 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung |
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| IT1256345B (it) * | 1992-08-20 | 1995-12-01 | Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione | |
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| JP3775796B2 (ja) * | 1993-10-06 | 2006-05-17 | ニコックス エス エイ | 抗炎症活性及び／又は鎮痛活性を有する硝酸エステル類及びそれらの製造方法 |
| RU2145595C1 (ru) * | 1994-05-10 | 2000-02-20 | Никокс С.А. | Нитроксисоединения и фармацевтическая композиция на их основе, имеющие противовоспалительную, анальгетическую и антитромбоцитарную активности |
| JPH09202764A (ja) * | 1996-01-24 | 1997-08-05 | Chugai Pharmaceut Co Ltd | ニトロ化合物 |
| IT1285770B1 (it) | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
| IT1295694B1 (it) | 1996-11-14 | 1999-05-27 | Nicox Sa | Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica |
| IT1311923B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
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1999
- 1999-08-12 IT IT1999MI001817A patent/IT1314184B1/it active
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2000
- 2000-07-27 DK DK00953102T patent/DK1252133T3/da active
- 2000-07-27 ES ES00953102T patent/ES2243292T3/es not_active Expired - Lifetime
- 2000-07-27 PL PL353451A patent/PL203200B1/pl not_active IP Right Cessation
- 2000-07-27 NZ NZ516889A patent/NZ516889A/en not_active IP Right Cessation
- 2000-07-27 NZ NZ535559A patent/NZ535559A/en not_active IP Right Cessation
- 2000-07-27 CN CNB2006101362310A patent/CN100528834C/zh not_active Expired - Fee Related
- 2000-07-27 AU AU65670/00A patent/AU781643B2/en not_active Ceased
- 2000-07-27 AT AT00953102T patent/ATE297375T1/de not_active IP Right Cessation
- 2000-07-27 IL IL14780100A patent/IL147801A0/xx not_active IP Right Cessation
- 2000-07-27 KR KR1020067024051A patent/KR100760394B1/ko not_active Expired - Fee Related
- 2000-07-27 EP EP05104064A patent/EP1593664A1/en not_active Withdrawn
- 2000-07-27 CA CA002381409A patent/CA2381409A1/en not_active Abandoned
- 2000-07-27 WO PCT/EP2000/007225 patent/WO2001012584A2/en not_active Ceased
- 2000-07-27 US US10/048,469 patent/US7186753B1/en not_active Expired - Fee Related
- 2000-07-27 BR BR0013264-0A patent/BR0013264A/pt active Search and Examination
- 2000-07-27 KR KR1020027001883A patent/KR100687809B1/ko not_active Expired - Fee Related
- 2000-07-27 RU RU2002103509/04A patent/RU2264383C2/ru not_active IP Right Cessation
- 2000-07-27 PT PT00953102T patent/PT1252133E/pt unknown
- 2000-07-27 CN CNB008140499A patent/CN1289466C/zh not_active Expired - Fee Related
- 2000-07-27 CA CA2698353A patent/CA2698353A1/en not_active Abandoned
- 2000-07-27 JP JP2001516885A patent/JP2003515526A/ja not_active Ceased
- 2000-07-27 MX MXPA02001519A patent/MXPA02001519A/es active IP Right Grant
- 2000-07-27 EP EP00953102A patent/EP1252133B1/en not_active Expired - Lifetime
- 2000-07-27 DE DE60020741T patent/DE60020741T2/de not_active Expired - Lifetime
- 2000-07-27 HU HU0203939A patent/HUP0203939A3/hu unknown
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2002
- 2002-01-23 ZA ZA200200628A patent/ZA200200628B/xx unknown
- 2002-02-08 NO NO20020623A patent/NO328498B1/no not_active IP Right Cessation
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2006
- 2006-12-21 US US11/642,783 patent/US7399878B2/en not_active Expired - Fee Related
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2008
- 2008-06-03 US US12/132,245 patent/US7759392B2/en not_active Expired - Fee Related
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2009
- 2009-10-29 NO NO20093253A patent/NO20093253L/no unknown