JP2002541086A - 強化された微生物的特徴を有するプロポフォール処方物 - Google Patents

強化された微生物的特徴を有するプロポフォール処方物

Info

Publication number
JP2002541086A
JP2002541086A JP2000609035A JP2000609035A JP2002541086A JP 2002541086 A JP2002541086 A JP 2002541086A JP 2000609035 A JP2000609035 A JP 2000609035A JP 2000609035 A JP2000609035 A JP 2000609035A JP 2002541086 A JP2002541086 A JP 2002541086A
Authority
JP
Japan
Prior art keywords
emulsion
propofol
water
oil
soybean oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000609035A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002541086A5 (https=
Inventor
サティシュ ケイ． ペジャバー，
ラジェシュウォー マザラム，
バレット イー． ラビナウ，
ロサ， ジョスベン， シー． デラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of JP2002541086A publication Critical patent/JP2002541086A/ja
Publication of JP2002541086A5 publication Critical patent/JP2002541086A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000609035A 1999-04-05 2000-03-29 強化された微生物的特徴を有するプロポフォール処方物 Pending JP2002541086A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/286,159 1999-04-05
US09/286,159 US6100302A (en) 1999-04-05 1999-04-05 Propofol formulation with enhanced microbial characteristics
PCT/US2000/008378 WO2000059471A1 (en) 1999-04-05 2000-03-29 Propofol formulation with enhanced microbial characteristics

Publications (2)

Publication Number Publication Date
JP2002541086A true JP2002541086A (ja) 2002-12-03
JP2002541086A5 JP2002541086A5 (https=) 2007-05-24

Family

ID=23097354

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000609035A Pending JP2002541086A (ja) 1999-04-05 2000-03-29 強化された微生物的特徴を有するプロポフォール処方物

Country Status (9)

Country Link
US (1) US6100302A (https=)
EP (1) EP1165045A1 (https=)
JP (1) JP2002541086A (https=)
KR (2) KR100861820B1 (https=)
AU (1) AU774259B2 (https=)
BR (1) BR0009541A (https=)
CA (1) CA2366793C (https=)
MX (1) MXPA01010064A (https=)
WO (1) WO2000059471A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013001700A (ja) * 2011-06-21 2013-01-07 Fujifilm Corp プロポフォール含有水中油型エマルション組成物
JP2013006811A (ja) * 2011-06-27 2013-01-10 Fujifilm Corp 容器詰製剤

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6749868B1 (en) 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
ES2211151T3 (es) 1998-08-19 2004-07-01 Skyepharma Canada Inc. Dispersiones acuosas inyectables de propofol.
EP2036540A3 (en) * 2000-06-16 2009-12-16 Jagotec AG Improved injectable dispersions of propofol
US6399087B1 (en) * 2000-12-20 2002-06-04 Amphastar Pharmaceuticals, Inc. Propofol formulation with enhanced microbial inhibition
US20030054042A1 (en) * 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
JP2005504090A (ja) 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
EP1430017A2 (en) 2001-09-26 2004-06-23 Theravance, Inc. Substituted phenol compounds useful for anesthesia and sedation
EP1490030B2 (en) * 2002-03-20 2010-07-14 Elan Pharma International Limited Nanoparticulate compositions of angiogenesis inhibitors
WO2003105817A1 (en) * 2002-05-02 2003-12-24 Fdl, Inc. Novel parenteral composition comprising propofol
KR100459025B1 (ko) * 2002-05-02 2004-12-03 (주) 에프디엘 프로포폴을 함유하는 신규한 주사제용 조성물
CN100438861C (zh) * 2002-07-29 2008-12-03 变换药品公司 含水2,6-二异丙基苯酚药物组合物
US7550155B2 (en) * 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
US20040171691A1 (en) * 2002-10-29 2004-09-02 Transform Pharmaceuticals, Inc. Propofol with cysteine
CN103405405A (zh) * 2002-12-09 2013-11-27 阿布拉西斯生物科学有限责任公司 组合物和传递药剂的方法
US20040225022A1 (en) * 2003-05-09 2004-11-11 Desai Neil P. Propofol formulation containing reduced oil and surfactants
US8476010B2 (en) 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures
US8546453B2 (en) 2003-08-14 2013-10-01 Rensheng Zhang Propofol compositions and methods for reducing pain associated with propofol injection
AU2005283726A1 (en) * 2004-09-13 2006-03-23 Bharat Serums & Vaccines Ltd. Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy
KR20080043793A (ko) * 2005-08-05 2008-05-19 바라트 쎄럼스 앤드 백신스 리미티드 방부 효능을 갖는 정맥 프로포폴 에멀젼 조성물
CN101287447B (zh) * 2005-08-12 2012-10-24 印度血清及疫苗有限公司 包含丙泊酚的水性麻醉剂组合物
KR101420445B1 (ko) 2005-08-31 2014-07-16 아브락시스 바이오사이언스, 엘엘씨 수 난용성 제약학적 약제 및 항균제를 포함하는 조성물
AU2006284657B2 (en) * 2005-08-31 2012-07-19 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
JP6247685B2 (ja) 2012-05-16 2017-12-13 メワ・シン 実質的に水不溶性の薬物の送達のための医薬組成物
CN104490780B (zh) * 2015-01-16 2017-04-19 河北一品制药有限公司 一种丙泊酚脂肪乳注射液的制备方法
US11622937B2 (en) 2015-08-20 2023-04-11 Mewa Singh Polyphenolic polymer to make water-insoluble molecules become water-soluble
CN110478366A (zh) * 2019-08-23 2019-11-22 宜昌人福药业有限责任公司 含非水溶性镇痛药的局部用组合物及其制备方法和用途
US11992483B2 (en) 2021-03-31 2024-05-28 Cali Biosciences Us, Llc Emulsions for local anesthetics

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034588A1 (en) * 1996-03-19 1997-09-25 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations
JPH11500737A (ja) * 1994-03-22 1999-01-19 ゼネカ・リミテッド プロポフォールとエデテートとを含有する水中油滴エマルジョン
JP2002523356A (ja) * 1998-08-19 2002-07-30 アールティーピー・ファーマ・インコーポレーテッド プロポフォールの注射可能水性分散物
JP2002528405A (ja) * 1998-10-23 2002-09-03 アボット・ラボラトリーズ プロポホール組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472793A (en) * 1974-03-28 1977-05-04 Ici Ltd Pharmaceutical compositions
BR9506681A (pt) * 1994-02-04 1997-11-18 Scotia Lipidteknik Ab Emulsão oleo em água e composição farmacêutica

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11500737A (ja) * 1994-03-22 1999-01-19 ゼネカ・リミテッド プロポフォールとエデテートとを含有する水中油滴エマルジョン
WO1997034588A1 (en) * 1996-03-19 1997-09-25 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations
JP2002523356A (ja) * 1998-08-19 2002-07-30 アールティーピー・ファーマ・インコーポレーテッド プロポフォールの注射可能水性分散物
JP2002528405A (ja) * 1998-10-23 2002-09-03 アボット・ラボラトリーズ プロポホール組成物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013001700A (ja) * 2011-06-21 2013-01-07 Fujifilm Corp プロポフォール含有水中油型エマルション組成物
JP2013006811A (ja) * 2011-06-27 2013-01-10 Fujifilm Corp 容器詰製剤

Also Published As

Publication number Publication date
WO2000059471A1 (en) 2000-10-12
CA2366793A1 (en) 2000-10-12
KR20010112400A (ko) 2001-12-20
BR0009541A (pt) 2002-01-02
KR100741604B1 (ko) 2007-07-20
KR20070058012A (ko) 2007-06-07
AU774259B2 (en) 2004-06-24
KR100861820B1 (ko) 2008-10-07
CA2366793C (en) 2009-06-02
AU4046300A (en) 2000-10-23
US6100302A (en) 2000-08-08
MXPA01010064A (es) 2002-06-21
EP1165045A1 (en) 2002-01-02

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