BR0313060A - Composições farmacêuticas aquosas de 2,6-diisopropilfenol - Google Patents
Composições farmacêuticas aquosas de 2,6-diisopropilfenolInfo
- Publication number
- BR0313060A BR0313060A BR0313060-6A BR0313060A BR0313060A BR 0313060 A BR0313060 A BR 0313060A BR 0313060 A BR0313060 A BR 0313060A BR 0313060 A BR0313060 A BR 0313060A
- Authority
- BR
- Brazil
- Prior art keywords
- diisopropylphenol
- pharmaceutical compositions
- propofol
- aqueous pharmaceutical
- compositions
- Prior art date
Links
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical group CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 4
- 229960004134 propofol Drugs 0.000 abstract 3
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"COMPOSIçõES FARMACêUTICAS AQUOSAS DE 2,6-DIISOPROPILFENOL". A presente invenção refere-se às composições farmacêuticas aquosas compreendendo 2,6-diisopropilfenol (propofol). A composição da presente invenção pode compreender propofol e dois ou mais excipientes como uma mistura aquosa. As composições contendo propofol são preferivelmente estéreis e são parenteralmente administradas em qualquer animal, incluindo seres humanos. As composições são também química e fisicamente estáveis em uma faixa ampla de condições ambientais.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39949002P | 2002-07-29 | 2002-07-29 | |
US42219502P | 2002-10-29 | 2002-10-29 | |
US43697902P | 2002-12-30 | 2002-12-30 | |
US46245003P | 2003-04-11 | 2003-04-11 | |
US46431403P | 2003-04-21 | 2003-04-21 | |
US47040303P | 2003-05-14 | 2003-05-14 | |
US48535403P | 2003-07-07 | 2003-07-07 | |
PCT/US2003/023512 WO2004010941A2 (en) | 2002-07-29 | 2003-07-29 | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0313060A true BR0313060A (pt) | 2005-06-28 |
Family
ID=31192580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0313060-6A BR0313060A (pt) | 2002-07-29 | 2003-07-29 | Composições farmacêuticas aquosas de 2,6-diisopropilfenol |
Country Status (15)
Country | Link |
---|---|
US (1) | US7915317B2 (pt) |
EP (1) | EP1539122B1 (pt) |
JP (3) | JP2005538191A (pt) |
KR (1) | KR101145692B1 (pt) |
CN (1) | CN100438861C (pt) |
AU (1) | AU2003261274C1 (pt) |
BR (1) | BR0313060A (pt) |
CA (1) | CA2494297C (pt) |
HK (1) | HK1077515A1 (pt) |
HR (1) | HRP20050182A2 (pt) |
MX (1) | MXPA05001061A (pt) |
NZ (1) | NZ538255A (pt) |
PL (1) | PL375874A1 (pt) |
RS (1) | RS54275B1 (pt) |
WO (1) | WO2004010941A2 (pt) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106581737A (zh) * | 2017-01-06 | 2017-04-26 | 哈尔滨鼓润生物技术有限公司 | 一种止血组合物及其制备方法 |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1539122B1 (en) | 2002-07-29 | 2014-01-29 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
US20040220283A1 (en) * | 2002-07-29 | 2004-11-04 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
US7550155B2 (en) * | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
CN1708270A (zh) * | 2002-10-29 | 2005-12-14 | 转化医药公司 | 丙泊酚与半胱氨酸 |
US20040225022A1 (en) * | 2003-05-09 | 2004-11-11 | Desai Neil P. | Propofol formulation containing reduced oil and surfactants |
US7754230B2 (en) | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
DK1758590T3 (da) | 2004-05-19 | 2011-11-21 | Los Angeles Biomed Res Inst | Anvendelse af et detergent til ikke-kirurgisk fjernelse af fedt |
US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
DE102004045622A1 (de) * | 2004-09-17 | 2006-03-30 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Konservierungsmittel-Zusammensetzungen |
WO2007128866A2 (en) * | 2006-05-09 | 2007-11-15 | Novobion Oy | Novel chemical compositions |
CA2656179A1 (en) * | 2006-06-21 | 2007-12-27 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US8197499B2 (en) * | 2006-06-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
US8608760B2 (en) * | 2006-06-21 | 2013-12-17 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
WO2008092084A2 (en) | 2007-01-26 | 2008-07-31 | Centocor, Inc. | Injectable non-aqueous suspension with high concentration of therapeutic agent |
JP2011507635A (ja) * | 2007-12-20 | 2011-03-10 | トートナ グループ, リミテッド パートナーシップ | 結合していない管腔を結合するための組成物および方法 |
CN101977619B (zh) | 2008-02-15 | 2013-06-05 | 诺沃百欧公司 | 姜黄素的可溶性复合物 |
US8563037B2 (en) * | 2009-02-06 | 2013-10-22 | Tautona Group, L.P. | Compositions and methods for joining non-conjoined lumens |
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
CN102858374B (zh) * | 2010-04-01 | 2015-12-09 | 帕玛内斯特公司 | 热胶凝麻醉剂组合物 |
US8754125B2 (en) | 2010-10-05 | 2014-06-17 | The Medicines Company | Antimicrobial preservation of propofol emulsions |
US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
HUE026295T2 (en) | 2010-10-12 | 2016-06-28 | The Medicines Co | Clevidipine emulsion formulations containing antimicrobial agents |
US20120237492A1 (en) | 2011-02-18 | 2012-09-20 | Kythera Biopharmaceuticals, Inc. | Treatment of submental fat |
US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
GB201106031D0 (en) | 2011-04-08 | 2011-05-25 | Highway Resource Solutions Ltd | Adaptions to a lantern |
WO2016061538A1 (en) | 2014-10-16 | 2016-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Novel methods, compounds, and compositions for anesthesia |
EP3383371B1 (en) * | 2015-12-09 | 2024-05-01 | Avecho Biotechnology Limited | Pharmaceutical formulation |
JP7198754B2 (ja) | 2016-12-21 | 2023-01-04 | アベーチョ バイオテクノロジー リミテッド | 方法 |
WO2018225229A1 (en) * | 2017-06-08 | 2018-12-13 | Terumo Kabushiki Kaisha | Parenteral aqueous pharmaceutical composition |
EP3946316A4 (en) * | 2019-04-05 | 2023-01-11 | Sorrento Therapeutics, Inc. | PHARMACEUTICAL CANNABIDIOL COMPOSITIONS |
CN114601800B (zh) * | 2021-09-28 | 2023-07-28 | 天津瑞普生物技术股份有限公司 | 一种甲磷丙泊酚钠无菌粉针剂及其制备方法 |
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US4798846A (en) * | 1974-03-28 | 1989-01-17 | Imperial Chemical Industries Plc | Pharmaceutical compositions |
GB1472793A (en) * | 1974-03-28 | 1977-05-04 | Ici Ltd | Pharmaceutical compositions |
US5296161A (en) | 1986-06-09 | 1994-03-22 | The Clorox Company | Enzymatic perhydrolysis system and method of use for bleaching |
HUT67762A (en) | 1991-03-19 | 1995-04-28 | Cytrx Corp | Polyoxypropylene/polyoxiethylene copolymers with improved biological activity and process for producing thereof |
US6277410B1 (en) | 1992-10-08 | 2001-08-21 | Supratek Pharma Inc. | Copolymer compositions for oral delivery |
US5731356A (en) | 1994-03-22 | 1998-03-24 | Zeneca Limited | Pharmaceutical compositions of propofol and edetate |
GB9405593D0 (en) | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
US5635540A (en) | 1994-12-09 | 1997-06-03 | The University Of Virginia Patent Foundation | Stabilized topical pharmaceutical preparations |
AU6708096A (en) | 1995-09-18 | 1997-04-09 | Vesifact Ag | Propofol nanodispersions |
US6077545A (en) | 1995-10-30 | 2000-06-20 | Matrix Pharmaceuticals, Inc. | Process and composition for therapeutic cisplatin (CDDP) |
US5637625A (en) | 1996-03-19 | 1997-06-10 | Research Triangle Pharmaceuticals Ltd. | Propofol microdroplet formulations |
US20020107291A1 (en) | 1997-05-26 | 2002-08-08 | Vincenzo De Tommaso | Clear, injectable formulation of an anesthetic compound |
US5962536A (en) | 1998-07-31 | 1999-10-05 | Komer; Gene | Injectable propofol formulations |
JP4198318B2 (ja) | 1998-08-19 | 2008-12-17 | ヤーゴテック アクチェンゲゼルシャフト | プロポフォールの注射可能水性分散物 |
US6150423A (en) * | 1998-10-15 | 2000-11-21 | Phoenix Scientific, Inc. | Propofol-based anesthetic and method of making same |
US6140374A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6140373A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6100302A (en) | 1999-04-05 | 2000-08-08 | Baxter International Inc. | Propofol formulation with enhanced microbial characteristics |
US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
ES2261210T3 (es) * | 1999-06-21 | 2006-11-16 | Kuhnil Pharmaceutical Co., Ltd. | Comoposicion anestesica para inyeccion intravenosa que comprende propofol. |
GB2359747B (en) | 2000-02-29 | 2002-04-24 | Maelor Pharmaceuticals Ltd | Anaesthetic formulations |
EP1289518A2 (en) | 2000-05-25 | 2003-03-12 | AstraZeneca AB | Pharmaceutical composition comprising a free-radical scavenging sedative agent and a metal ion chelating agent |
US6726919B2 (en) | 2000-06-16 | 2004-04-27 | Rtp Pharma, Inc. | Injectable dispersion of propofol |
IN187686B (pt) * | 2000-06-21 | 2002-06-08 | Bharat Serums & Vaccines Ltd | |
US6623765B1 (en) | 2000-08-01 | 2003-09-23 | University Of Florida, Research Foundation, Incorporated | Microemulsion and micelle systems for solubilizing drugs |
IN188917B (pt) | 2000-12-07 | 2002-11-23 | Bharat Surums & Vaccines Ltd | |
US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
WO2002074200A1 (en) | 2001-03-20 | 2002-09-26 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
GB0120702D0 (en) | 2001-08-24 | 2001-10-17 | Maelor Pharmaceuticals Ltd | Anaesthetic formulations |
GB0124071D0 (en) * | 2001-10-08 | 2001-11-28 | Kbig Ltd | Improvement in the administration of high boiling point aneasthetics |
US20040220283A1 (en) | 2002-07-29 | 2004-11-04 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
US7550155B2 (en) | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
EP1539122B1 (en) | 2002-07-29 | 2014-01-29 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
KR100482269B1 (ko) | 2002-10-08 | 2005-04-14 | 센츄론(주) | 2,6-디이소프로필페놀을 활성성분으로 하는 수용액상의마취용 주사제 및 그 제조방법 |
US8476010B2 (en) | 2003-07-10 | 2013-07-02 | App Pharmaceuticals Llc | Propofol formulations with non-reactive container closures |
-
2003
- 2003-07-29 EP EP03771951.5A patent/EP1539122B1/en not_active Expired - Lifetime
- 2003-07-29 CN CNB038180758A patent/CN100438861C/zh not_active Expired - Fee Related
- 2003-07-29 MX MXPA05001061A patent/MXPA05001061A/es active IP Right Grant
- 2003-07-29 WO PCT/US2003/023512 patent/WO2004010941A2/en active Application Filing
- 2003-07-29 PL PL03375874A patent/PL375874A1/xx unknown
- 2003-07-29 BR BR0313060-6A patent/BR0313060A/pt not_active Application Discontinuation
- 2003-07-29 NZ NZ538255A patent/NZ538255A/en not_active IP Right Cessation
- 2003-07-29 AU AU2003261274A patent/AU2003261274C1/en not_active Ceased
- 2003-07-29 KR KR1020057001649A patent/KR101145692B1/ko active IP Right Grant
- 2003-07-29 CA CA2494297A patent/CA2494297C/en not_active Expired - Fee Related
- 2003-07-29 US US10/629,308 patent/US7915317B2/en not_active Expired - Fee Related
- 2003-07-29 JP JP2005505627A patent/JP2005538191A/ja not_active Withdrawn
- 2003-07-29 RS YU20050066A patent/RS54275B1/sr unknown
-
2005
- 2005-02-24 HR HR20050182A patent/HRP20050182A2/xx not_active Application Discontinuation
- 2005-11-28 HK HK05110804.0A patent/HK1077515A1/xx not_active IP Right Cessation
-
2010
- 2010-11-29 JP JP2010265559A patent/JP2011144161A/ja active Pending
-
2013
- 2013-11-29 JP JP2013248238A patent/JP2014058553A/ja active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106581737A (zh) * | 2017-01-06 | 2017-04-26 | 哈尔滨鼓润生物技术有限公司 | 一种止血组合物及其制备方法 |
CN106581737B (zh) * | 2017-01-06 | 2019-09-06 | 哈尔滨鼓润生物技术有限公司 | 一种止血组合物及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
RS20050066A (en) | 2007-09-21 |
HK1077515A1 (en) | 2006-02-17 |
JP2014058553A (ja) | 2014-04-03 |
NZ538255A (en) | 2006-11-30 |
HRP20050182A2 (en) | 2006-11-30 |
WO2004010941A3 (en) | 2004-06-17 |
WO2004010941A2 (en) | 2004-02-05 |
EP1539122B1 (en) | 2014-01-29 |
AU2003261274A1 (en) | 2004-02-16 |
AU2003261274C1 (en) | 2009-02-12 |
CA2494297C (en) | 2011-10-18 |
PL375874A1 (en) | 2005-12-12 |
CA2494297A1 (en) | 2004-02-05 |
RS54275B1 (sr) | 2016-02-29 |
EP1539122A2 (en) | 2005-06-15 |
JP2011144161A (ja) | 2011-07-28 |
EP1539122A4 (en) | 2010-03-10 |
JP2005538191A (ja) | 2005-12-15 |
CN1671367A (zh) | 2005-09-21 |
KR101145692B1 (ko) | 2012-05-25 |
US20050027019A1 (en) | 2005-02-03 |
KR20050026539A (ko) | 2005-03-15 |
US7915317B2 (en) | 2011-03-29 |
AU2003261274B2 (en) | 2008-07-31 |
MXPA05001061A (es) | 2005-10-05 |
CN100438861C (zh) | 2008-12-03 |
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