HRP20050182A2 - Aqueous 2,6-diisopropylphenol pharmaceutical compositions - Google Patents

Aqueous 2,6-diisopropylphenol pharmaceutical compositions

Info

Publication number
HRP20050182A2
HRP20050182A2 HR20050182A HRP20050182A HRP20050182A2 HR P20050182 A2 HRP20050182 A2 HR P20050182A2 HR 20050182 A HR20050182 A HR 20050182A HR P20050182 A HRP20050182 A HR P20050182A HR P20050182 A2 HRP20050182 A2 HR P20050182A2
Authority
HR
Croatia
Prior art keywords
diisopropylphenol
pharmaceutical compositions
aqueous
propofol
present
Prior art date
Application number
HR20050182A
Other languages
English (en)
Croatian (hr)
Inventor
Zhang Zhong
Almarsson Orn
Chen Hongming
Original Assignee
Transform Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transform Pharmaceuticals filed Critical Transform Pharmaceuticals
Publication of HRP20050182A2 publication Critical patent/HRP20050182A2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR20050182A 2002-07-29 2005-02-24 Aqueous 2,6-diisopropylphenol pharmaceutical compositions HRP20050182A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US39949002P 2002-07-29 2002-07-29
US42219502P 2002-10-29 2002-10-29
US43697902P 2002-12-30 2002-12-30
US46245003P 2003-04-11 2003-04-11
US46431403P 2003-04-21 2003-04-21
US47040303P 2003-05-14 2003-05-14
US48535403P 2003-07-07 2003-07-07
PCT/US2003/023512 WO2004010941A2 (en) 2002-07-29 2003-07-29 Aqueous 2,6-diisopropylphenol pharmaceutical compositions

Publications (1)

Publication Number Publication Date
HRP20050182A2 true HRP20050182A2 (en) 2006-11-30

Family

ID=31192580

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050182A HRP20050182A2 (en) 2002-07-29 2005-02-24 Aqueous 2,6-diisopropylphenol pharmaceutical compositions

Country Status (15)

Country Link
US (1) US7915317B2 (xx)
EP (1) EP1539122B1 (xx)
JP (3) JP2005538191A (xx)
KR (1) KR101145692B1 (xx)
CN (1) CN100438861C (xx)
AU (1) AU2003261274C1 (xx)
BR (1) BR0313060A (xx)
CA (1) CA2494297C (xx)
HK (1) HK1077515A1 (xx)
HR (1) HRP20050182A2 (xx)
MX (1) MXPA05001061A (xx)
NZ (1) NZ538255A (xx)
PL (1) PL375874A1 (xx)
RS (1) RS54275B1 (xx)
WO (1) WO2004010941A2 (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040220283A1 (en) * 2002-07-29 2004-11-04 Transform Pharmaceuticals, Inc. Aqueous 2,6-diisopropylphenol pharmaceutical compositions
NZ538255A (en) 2002-07-29 2006-11-30 Transform Pharmaceuticals Inc Aqueous 2,6-diisopropylphenol pharmaceutical compositions
US7550155B2 (en) * 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
AU2003286725B2 (en) * 2002-10-29 2007-07-12 Transform Pharmaceuticals, Inc. Propofol with cysteine
US20040225022A1 (en) * 2003-05-09 2004-11-11 Desai Neil P. Propofol formulation containing reduced oil and surfactants
TR201802446T4 (tr) 2004-05-19 2018-03-21 Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct Sodyum deoksikolat içeren enjeksiyonluk bileşim.
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
DE102004045622A1 (de) * 2004-09-17 2006-03-30 Aquanova German Solubilisate Technologies (Agt) Gmbh Konservierungsmittel-Zusammensetzungen
WO2007128866A2 (en) * 2006-05-09 2007-11-15 Novobion Oy Novel chemical compositions
US8197499B2 (en) * 2006-06-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
US8608760B2 (en) * 2006-06-21 2013-12-17 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
AU2007260924A1 (en) * 2006-06-21 2007-12-27 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
US20090022727A1 (en) 2007-01-26 2009-01-22 Alza Corp. Injectable, nonaqueous suspension with high concentration of therapeutic agent
CA2710002A1 (en) * 2007-12-20 2009-07-09 Tautona Group, L.P. Compositions and methods for joining non-conjoined lumens
JP2011512346A (ja) 2008-02-15 2011-04-21 ノボビオン オイ クルクミンの可溶性錯体
US8563037B2 (en) * 2009-02-06 2013-10-22 Tautona Group, L.P. Compositions and methods for joining non-conjoined lumens
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
MX2012011262A (es) 2010-04-01 2013-02-11 Pharmanest Ab Composiciones anestesicas termogelificantes.
WO2012047870A2 (en) * 2010-10-05 2012-04-12 The Medicines Company Antimicrobial preservation of propofol emulsions
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EP2627173B2 (en) * 2010-10-12 2018-07-04 Chiesi Farmaceutici S.p.A. Clevidipine emulsion formulations containing antimicrobial agents
WO2012112940A1 (en) 2011-02-18 2012-08-23 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
GB201106031D0 (en) 2011-04-08 2011-05-25 Highway Resource Solutions Ltd Adaptions to a lantern
EP3206683A4 (en) 2014-10-16 2018-06-13 The Board of Trustees of the Leland Stanford Junior University Novel methods, compounds, and compositions for anesthesia
CN114712308A (zh) * 2015-12-09 2022-07-08 磷肌酸有限公司 药物制剂
MX2019006845A (es) 2016-12-21 2019-10-15 Avecho Biotechnology Ltd Proceso.
CN106581737B (zh) * 2017-01-06 2019-09-06 哈尔滨鼓润生物技术有限公司 一种止血组合物及其制备方法
WO2018225229A1 (en) * 2017-06-08 2018-12-13 Terumo Kabushiki Kaisha Parenteral aqueous pharmaceutical composition
CN113905731A (zh) * 2019-04-05 2022-01-07 索伦托药业有限公司 大麻二酚药物组合物
CN114601800B (zh) * 2021-09-28 2023-07-28 天津瑞普生物技术股份有限公司 一种甲磷丙泊酚钠无菌粉针剂及其制备方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472793A (en) * 1974-03-28 1977-05-04 Ici Ltd Pharmaceutical compositions
US4798846A (en) * 1974-03-28 1989-01-17 Imperial Chemical Industries Plc Pharmaceutical compositions
US5296161A (en) * 1986-06-09 1994-03-22 The Clorox Company Enzymatic perhydrolysis system and method of use for bleaching
DK0576612T3 (da) * 1991-03-19 2000-05-22 Cytrx Corp Polyoxypropylen/polyoxyethylen-copolymerer med forbedret aktivitet
US6277410B1 (en) * 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
GB9405593D0 (en) 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
US5731356A (en) * 1994-03-22 1998-03-24 Zeneca Limited Pharmaceutical compositions of propofol and edetate
US5635540A (en) * 1994-12-09 1997-06-03 The University Of Virginia Patent Foundation Stabilized topical pharmaceutical preparations
WO1997010814A1 (en) 1995-09-18 1997-03-27 Vesifact Ag Propofol nanodispersions
US6077545A (en) * 1995-10-30 2000-06-20 Matrix Pharmaceuticals, Inc. Process and composition for therapeutic cisplatin (CDDP)
US5637625A (en) * 1996-03-19 1997-06-10 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations
US20020107291A1 (en) * 1997-05-26 2002-08-08 Vincenzo De Tommaso Clear, injectable formulation of an anesthetic compound
US5962536A (en) 1998-07-31 1999-10-05 Komer; Gene Injectable propofol formulations
US7097849B2 (en) * 1998-08-19 2006-08-29 Jagotec Ag Injectable aqueous dispersions of propofol
US6150423A (en) * 1998-10-15 2000-11-21 Phoenix Scientific, Inc. Propofol-based anesthetic and method of making same
US6140373A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6100302A (en) * 1999-04-05 2000-08-08 Baxter International Inc. Propofol formulation with enhanced microbial characteristics
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
ATE327741T1 (de) * 1999-06-21 2006-06-15 Kuhnil Pharmaceutical Co Ltd Propofol enthaltende anästhetische zusammensetzung zur intravenösen injektion
GB2359747B (en) 2000-02-29 2002-04-24 Maelor Pharmaceuticals Ltd Anaesthetic formulations
WO2001089514A2 (en) 2000-05-25 2001-11-29 Astrazeneca Ab Pharmaceutical composition comprising a free-radical scavenging sedative agent and a metal ion chelating agent
IL153457A0 (en) 2000-06-16 2003-07-06 Skyepharma Canada Inc Improved injectable dispersions of propofol
IN187686B (xx) 2000-06-21 2002-06-08 Bharat Serums & Vaccines Ltd
US6623765B1 (en) * 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
IN188917B (xx) 2000-12-07 2002-11-23 Bharat Surums & Vaccines Ltd
JP4334229B2 (ja) 2001-03-20 2009-09-30 サイデックス・ファーマシューティカルズ・インコーポレイテッド プロポフォール及びスルホアルキルエーテルシクロデキストリン含有製剤
US7034013B2 (en) * 2001-03-20 2006-04-25 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
GB0120702D0 (en) 2001-08-24 2001-10-17 Maelor Pharmaceuticals Ltd Anaesthetic formulations
GB0124071D0 (en) 2001-10-08 2001-11-28 Kbig Ltd Improvement in the administration of high boiling point aneasthetics
NZ538255A (en) 2002-07-29 2006-11-30 Transform Pharmaceuticals Inc Aqueous 2,6-diisopropylphenol pharmaceutical compositions
US20040220283A1 (en) * 2002-07-29 2004-11-04 Transform Pharmaceuticals, Inc. Aqueous 2,6-diisopropylphenol pharmaceutical compositions
US7550155B2 (en) * 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
KR100482269B1 (ko) 2002-10-08 2005-04-14 센츄론(주) 2,6-디이소프로필페놀을 활성성분으로 하는 수용액상의마취용 주사제 및 그 제조방법
US8476010B2 (en) * 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures

Also Published As

Publication number Publication date
EP1539122B1 (en) 2014-01-29
RS54275B1 (sr) 2016-02-29
CA2494297C (en) 2011-10-18
AU2003261274A1 (en) 2004-02-16
KR101145692B1 (ko) 2012-05-25
JP2005538191A (ja) 2005-12-15
JP2014058553A (ja) 2014-04-03
NZ538255A (en) 2006-11-30
US20050027019A1 (en) 2005-02-03
AU2003261274C1 (en) 2009-02-12
PL375874A1 (en) 2005-12-12
CN100438861C (zh) 2008-12-03
MXPA05001061A (es) 2005-10-05
RS20050066A (xx) 2007-09-21
WO2004010941A3 (en) 2004-06-17
HK1077515A1 (en) 2006-02-17
CN1671367A (zh) 2005-09-21
CA2494297A1 (en) 2004-02-05
EP1539122A4 (en) 2010-03-10
JP2011144161A (ja) 2011-07-28
WO2004010941A2 (en) 2004-02-05
US7915317B2 (en) 2011-03-29
BR0313060A (pt) 2005-06-28
EP1539122A2 (en) 2005-06-15
AU2003261274B2 (en) 2008-07-31
KR20050026539A (ko) 2005-03-15

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