ATE412404T1 - Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon - Google Patents
Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davonInfo
- Publication number
- ATE412404T1 ATE412404T1 AT04735713T AT04735713T ATE412404T1 AT E412404 T1 ATE412404 T1 AT E412404T1 AT 04735713 T AT04735713 T AT 04735713T AT 04735713 T AT04735713 T AT 04735713T AT E412404 T1 ATE412404 T1 AT E412404T1
- Authority
- AT
- Austria
- Prior art keywords
- buprenorphine
- salt
- oral pharmaceutical
- pharmaceutical compositions
- stable oral
- Prior art date
Links
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 title abstract 3
- 229960001736 buprenorphine Drugs 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000008203 oral pharmaceutical composition Substances 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 abstract 2
- 230000003078 antioxidant effect Effects 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/BE2004/000081 WO2005117838A1 (en) | 2004-06-02 | 2004-06-02 | Stable oral pharmaceutical compositions of buprenorphine and derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412404T1 true ATE412404T1 (de) | 2008-11-15 |
Family
ID=34957905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04735713T ATE412404T1 (de) | 2004-06-02 | 2004-06-02 | Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1750675B1 (de) |
| AT (1) | ATE412404T1 (de) |
| DE (1) | DE602004017514D1 (de) |
| WO (1) | WO2005117838A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140271788A1 (en) * | 2013-03-15 | 2014-09-18 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| RS51211B (sr) | 2006-04-04 | 2010-12-31 | Emodis Gmbh. | Primena formulacija koje sadrže kapa-opioid receptor-agoniste za tretman disocijativnih poremećaja |
| GB2461681A (en) * | 2008-04-17 | 2010-01-13 | Pharmasol Ltd | Buprenorphine liquid spray formulation with solvent and antioxidant |
| US8491937B2 (en) * | 2007-02-15 | 2013-07-23 | Wyeth Llc | Stability in vitamin and mineral supplements |
| GB2450117A (en) * | 2007-06-13 | 2008-12-17 | Reckitt Benckiser Healthcare | A water- and oxygen-occlusive blister tablet pack |
| AU2013245546C1 (en) * | 2011-09-19 | 2017-08-24 | Orexo Ab | New abuse-resistant pharmaceutical composition for the treatment of opioid dependence |
| MX361757B (es) * | 2011-09-19 | 2018-12-13 | Orexo Ab | Nueva composicion farmaceutica resistente al abuso para el tratamiento de la dependencia de opioides. |
| BR112015025684A2 (pt) * | 2013-04-08 | 2017-07-18 | Indivior Uk Ltd | método para proporcionar um ou mais opióide(s) a um indivíduo, forma de dosagem, método para tratar ou prevenir dor e método para tratar ou prevenir dependência ou vício |
| RU2635993C1 (ru) * | 2016-09-09 | 2017-11-17 | Закрытое акционерное общество "Научно-производственное объединение "ДОМ ФАРМАЦИИ" | Композиция убихинола для парентерального введения и способ её получения |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1302682B1 (it) * | 1998-10-16 | 2000-09-29 | Formenti Farmaceutici Spa | Composizioni farmaceutiche orali contenenti buprenorfina |
| GB0214147D0 (en) * | 2002-06-19 | 2002-07-31 | Glaxo Group Ltd | Formulations |
-
2004
- 2004-06-02 AT AT04735713T patent/ATE412404T1/de not_active IP Right Cessation
- 2004-06-02 EP EP04735713A patent/EP1750675B1/de not_active Expired - Lifetime
- 2004-06-02 WO PCT/BE2004/000081 patent/WO2005117838A1/en not_active Ceased
- 2004-06-02 DE DE602004017514T patent/DE602004017514D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1750675B1 (de) | 2008-10-29 |
| EP1750675A1 (de) | 2007-02-14 |
| WO2005117838A1 (en) | 2005-12-15 |
| DE602004017514D1 (de) | 2008-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |