ATE412404T1 - Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon - Google Patents

Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon

Info

Publication number
ATE412404T1
ATE412404T1 AT04735713T AT04735713T ATE412404T1 AT E412404 T1 ATE412404 T1 AT E412404T1 AT 04735713 T AT04735713 T AT 04735713T AT 04735713 T AT04735713 T AT 04735713T AT E412404 T1 ATE412404 T1 AT E412404T1
Authority
AT
Austria
Prior art keywords
buprenorphine
salt
oral pharmaceutical
pharmaceutical compositions
stable oral
Prior art date
Application number
AT04735713T
Other languages
English (en)
Inventor
Francis Vanderbist
Antonio Sereno
Philippe Baudier
Original Assignee
Galephar M F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galephar M F filed Critical Galephar M F
Application granted granted Critical
Publication of ATE412404T1 publication Critical patent/ATE412404T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04735713T 2004-06-02 2004-06-02 Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon ATE412404T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BE2004/000081 WO2005117838A1 (en) 2004-06-02 2004-06-02 Stable oral pharmaceutical compositions of buprenorphine and derivatives

Publications (1)

Publication Number Publication Date
ATE412404T1 true ATE412404T1 (de) 2008-11-15

Family

ID=34957905

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04735713T ATE412404T1 (de) 2004-06-02 2004-06-02 Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon

Country Status (4)

Country Link
EP (1) EP1750675B1 (de)
AT (1) ATE412404T1 (de)
DE (1) DE602004017514D1 (de)
WO (1) WO2005117838A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140271788A1 (en) * 2013-03-15 2014-09-18 Monosol Rx, Llc Sublingual and buccal film compositions
WO2007115975A2 (de) * 2006-04-04 2007-10-18 Holger Lars Hermann Verwendung von zusammensetzungen enthaltend kappa-opioidrezeptor-antagonisten zur behandlung von dissoziativen störungen
GB2461681A (en) * 2008-04-17 2010-01-13 Pharmasol Ltd Buprenorphine liquid spray formulation with solvent and antioxidant
US8491937B2 (en) * 2007-02-15 2013-07-23 Wyeth Llc Stability in vitamin and mineral supplements
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
PL2915525T3 (pl) * 2011-09-19 2022-01-17 Orexo Ab Tabletki podjęzykowe niepodatne na nadużywanie zawierające buprenorfinę i nalokson
AU2013245546C1 (en) * 2011-09-19 2017-08-24 Orexo Ab New abuse-resistant pharmaceutical composition for the treatment of opioid dependence
US20160051536A1 (en) * 2013-04-08 2016-02-25 Virginia Commonwealth University Compositions to alleviate presystemic metabolism of opioids
RU2635993C1 (ru) * 2016-09-09 2017-11-17 Закрытое акционерное общество "Научно-производственное объединение "ДОМ ФАРМАЦИИ" Композиция убихинола для парентерального введения и способ её получения

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1302682B1 (it) * 1998-10-16 2000-09-29 Formenti Farmaceutici Spa Composizioni farmaceutiche orali contenenti buprenorfina
GB0214147D0 (en) * 2002-06-19 2002-07-31 Glaxo Group Ltd Formulations

Also Published As

Publication number Publication date
DE602004017514D1 (de) 2008-12-11
WO2005117838A1 (en) 2005-12-15
EP1750675B1 (de) 2008-10-29
EP1750675A1 (de) 2007-02-14

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties