JP2002535450A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002535450A5 JP2002535450A5 JP2000594947A JP2000594947A JP2002535450A5 JP 2002535450 A5 JP2002535450 A5 JP 2002535450A5 JP 2000594947 A JP2000594947 A JP 2000594947A JP 2000594947 A JP2000594947 A JP 2000594947A JP 2002535450 A5 JP2002535450 A5 JP 2002535450A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- monolayer
- sample
- molecules
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 description 27
- 239000000523 sample Substances 0.000 description 16
- 239000002356 single layer Substances 0.000 description 16
- 238000000034 method Methods 0.000 description 12
- 125000000524 functional group Chemical group 0.000 description 8
- 102000039446 nucleic acids Human genes 0.000 description 7
- 108020004707 nucleic acids Proteins 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 239000010410 layer Substances 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 3
- 239000003999 initiator Substances 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 150000008365 aromatic ketones Chemical class 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 239000003505 polymerization initiator Substances 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 150000003923 2,5-pyrrolediones Chemical class 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- WHNPOQXWAMXPTA-UHFFFAOYSA-N 3-methylbut-2-enamide Chemical compound CC(C)=CC(N)=O WHNPOQXWAMXPTA-UHFFFAOYSA-N 0.000 description 1
- 239000005046 Chlorosilane Substances 0.000 description 1
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- NQTADLQHYWFPDB-UHFFFAOYSA-N N-Hydroxysuccinimide Chemical class ON1C(=O)CCC1=O NQTADLQHYWFPDB-UHFFFAOYSA-N 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- -1 alkoxysilane Chemical compound 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 150000001540 azides Chemical class 0.000 description 1
- 125000000751 azo group Chemical group [*]N=N[*] 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- KOPOQZFJUQMUML-UHFFFAOYSA-N chlorosilane Chemical compound Cl[SiH3] KOPOQZFJUQMUML-UHFFFAOYSA-N 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 150000002118 epoxides Chemical class 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 150000002540 isothiocyanates Chemical class 0.000 description 1
- 125000000468 ketone group Chemical group 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 238000001668 nucleic acid synthesis Methods 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99101340 | 1999-01-25 | ||
| EP99101340.0 | 1999-01-25 | ||
| EP99104278.9 | 1999-03-03 | ||
| EP99104278A EP1035218A1 (en) | 1999-03-03 | 1999-03-03 | Immobilization of molecules on surfaces via polymer brushes |
| PCT/EP2000/000554 WO2000043539A2 (en) | 1999-01-25 | 2000-01-25 | Immobilization of molecules on surfaces via polymer brushes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002535450A JP2002535450A (ja) | 2002-10-22 |
| JP2002535450A5 true JP2002535450A5 (https=) | 2007-02-22 |
| JP4970654B2 JP4970654B2 (ja) | 2012-07-11 |
Family
ID=26152863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000594947A Expired - Fee Related JP4970654B2 (ja) | 1999-01-25 | 2000-01-25 | ポリマーブラシを介する表面上での分子の固定化 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7250253B1 (https=) |
| EP (1) | EP1144677B1 (https=) |
| JP (1) | JP4970654B2 (https=) |
| AT (1) | ATE334226T1 (https=) |
| AU (1) | AU3150400A (https=) |
| CA (1) | CA2360027A1 (https=) |
| DE (1) | DE60029561T2 (https=) |
| WO (1) | WO2000043539A2 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60027309T2 (de) | 1999-07-02 | 2006-08-31 | Symyx Technologies, Inc., Santa Clara | Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen |
| KR100608152B1 (ko) * | 1999-07-07 | 2006-08-04 | 미러스 코포레이션 | 고체 지지체 상에 핵산을 고정시키기 위한 기판 |
| CA2317179A1 (en) | 1999-09-01 | 2001-03-01 | Affymetrix, Inc. | Macromolecular arrays on polymeric brushes and methods for preparing the same |
| FR2802550B1 (fr) * | 1999-12-17 | 2004-03-05 | Centre Nat Rech Scient | Biopuces, preparation et utilisations |
| DE60033648T2 (de) * | 2000-07-27 | 2007-11-08 | Micronas Holding Gmbh | Auf einer Oberfläche befestigte polyfunktionelle Polymernetzwerke für Sensorchips |
| ATE316581T1 (de) | 2000-09-05 | 2006-02-15 | Zeltz Patrick Dr | Verfahren zur spezifischen bestimmung von dna- sequenzen mittels paralleler amplifikation |
| ATE355526T1 (de) * | 2000-10-31 | 2006-03-15 | Micronas Gmbh | Gemusterte polymeroberflächen geeignet für biokonjugationen und verfahren zu ihrer herstellung |
| WO2002056021A2 (en) * | 2001-01-10 | 2002-07-18 | Symyx Technologies Inc | Polymer brushes for immobilizing molecules to a surface |
| US20030068317A1 (en) * | 2001-04-20 | 2003-04-10 | William Lee | High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon |
| EP1572896A4 (en) * | 2001-07-30 | 2006-06-07 | Angiotech Biocoatings Corp | PFROPFPOLYMERMATRIZES |
| AU2002361223A1 (en) * | 2001-08-27 | 2003-03-18 | Zeptosens Ag | Bioanalytical recognition surface with optimised recognition element density |
| US6867295B2 (en) | 2001-09-07 | 2005-03-15 | Dionex Corporation | Ion exchange cryptands covalently bound to substrates |
| AU2002360298A1 (en) * | 2001-12-10 | 2003-06-23 | Emembrane, Inc. | Functionalized materials and libraries thereof |
| JP2003294742A (ja) * | 2002-03-29 | 2003-10-15 | Inst Of Physical & Chemical Res | ハイブリダイゼーション用基板及びその使用方法 |
| US20060111517A1 (en) * | 2002-08-08 | 2006-05-25 | Hans-Dieter Feucht | Recognition layers made of hydrogel based on polyacrylamide for use in biosensor technology |
| DE60312525T2 (de) * | 2002-08-09 | 2007-12-06 | Ottawa Health Research Institute, Ottawa | Biosynthetische matrix und deren verwendung |
| AU2003270769A1 (en) * | 2002-09-18 | 2004-04-08 | Emembrane, Inc. | Functionalized materials and methods of using same |
| DE10245435B4 (de) | 2002-09-27 | 2006-03-16 | Micronas Gmbh | Vorrichtung zur Detektion mindestens eines in einer zu untersuchenden Probe enthaltenen Liganden |
| DE10328730B4 (de) * | 2003-06-25 | 2006-08-17 | Micronas Gmbh | Verfahren zum Herstellen eines Microarrays und Vorrichtung zum Versehen eines Trägers für ein Microarray mit Beschichtungsstoffen |
| US7354706B2 (en) | 2003-09-09 | 2008-04-08 | The Regents Of The University Of Colorado, A Body Corporate | Use of photopolymerization for amplification and detection of a molecular recognition event |
| US20090163375A1 (en) | 2003-09-09 | 2009-06-25 | Bowman Christopher N | Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event |
| DE102004010430A1 (de) | 2004-03-01 | 2005-09-22 | Rühe, Jürgen, Prof. Dr. | Verfahren zur kovalenten Immobilisierung von Biomolekülen an organischen Oberflächen |
| US7514764B2 (en) * | 2005-03-23 | 2009-04-07 | Wisconsin Alumni Research Foundation | Materials and methods for creating imaging layers |
| DE102005022782A1 (de) | 2005-05-12 | 2006-11-16 | Tesa Ag | Haftklebemassen und Verfahren zu deren Herstellung |
| WO2006128644A1 (en) * | 2005-05-30 | 2006-12-07 | Giovanna Pirri | Polymer coating and functionalization of solid surfaces |
| US8357433B2 (en) | 2005-06-14 | 2013-01-22 | Siemens Energy, Inc. | Polymer brushes |
| US7862886B2 (en) * | 2005-08-12 | 2011-01-04 | Fujifilm Corporation | Optical film, antireflection film, processes for producing the same, and polarizing plate and display employing the same |
| EP1811300B1 (de) | 2005-12-23 | 2008-11-12 | Micronas GmbH | Sensorchip mit in einem Polymer-Netzwerk eingelagerten Rezeptoren |
| KR100838124B1 (ko) * | 2007-02-01 | 2008-06-13 | 포항공과대학교 산학협력단 | 생체적합성 지방족 브러쉬 고분자 및 그 제조 방법 |
| DE102008032570A1 (de) | 2008-07-11 | 2010-01-14 | Tesa Se | Haftklebemassen und Verfahren zu deren Herstellung |
| EP2192409B1 (en) | 2008-11-26 | 2014-04-23 | Corning Incorporated | Label independent detection biosensor composition and methods thereof |
| DE102009060626A1 (de) | 2009-12-24 | 2011-06-30 | Klapproth, Holger, Dr., 79108 | Kalibrierte Flusszelle zur IR-Analytik |
| EP2598562A4 (en) * | 2010-07-30 | 2014-01-15 | United Resource Recovery Corp | SURFACE FUNCTIONALIZATION OF POLYESTERS |
| US20130316430A1 (en) | 2011-02-01 | 2013-11-28 | Maharshi Dayanand University | Polyvinyl chloride surface co-immobilized with enzymes and uses thereof |
| EP2718691B1 (de) | 2011-06-09 | 2017-12-13 | QFood GmbH | Verfahren und vorrichtung zum bestimmen der konzentration eines in einer flüssigen probe enthaltenen analyten |
| EP2812091B1 (en) | 2012-09-17 | 2021-03-10 | W.R. Grace & CO. - CONN. | Chromatography media and devices |
| EP2811983B1 (en) | 2012-09-17 | 2019-05-01 | W.R. Grace & CO. - CONN. | Functionalized particulate support material and methods of making and using the same |
| JP6453210B2 (ja) | 2013-05-13 | 2019-01-16 | 国立研究開発法人科学技術振興機構 | 新規複合材料およびそれを用いるポリマー被覆材前駆体 |
| CN107002117B (zh) | 2013-12-05 | 2021-12-10 | 生捷科技控股公司 | 核酸测序方法 |
| US10385335B2 (en) | 2013-12-05 | 2019-08-20 | Centrillion Technology Holdings Corporation | Modified surfaces |
| CN106460032B (zh) | 2013-12-05 | 2019-12-24 | 生捷科技控股公司 | 图案化阵列的制备 |
| ES2887110T3 (es) | 2014-01-16 | 2021-12-21 | Grace W R & Co | Medios para cromatografía de afinidad y dispositivos para cromatografía |
| US11060139B2 (en) | 2014-03-28 | 2021-07-13 | Centrillion Technology Holdings Corporation | Methods for sequencing nucleic acids |
| PL3137209T3 (pl) | 2014-05-02 | 2023-01-02 | W.R. Grace & Co. - Conn. | Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego |
| KR102566292B1 (ko) | 2015-06-05 | 2023-08-10 | 더블유.알. 그레이스 앤드 캄파니-콘. | 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63233360A (ja) * | 1986-12-15 | 1988-09-29 | Fuji Photo Film Co Ltd | 電気泳動用媒体 |
| SE8801070D0 (sv) * | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| JPH05502585A (ja) * | 1989-12-04 | 1993-05-13 | ベクトン ディッキンソン アンド カンパニー | ポリマーに共有結合したオリゴヌクレオチドの利用により向上される標的核酸の捕獲 |
| BR9206705A (pt) * | 1991-11-01 | 1995-11-21 | Adelaide Children S Hospital | Processo de amplificação de fase sólida |
| US5624711A (en) * | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
| SE9502608D0 (sv) | 1995-07-14 | 1995-07-14 | Pharmacia Biosensor Ab | Method for nucleic acid senquencing |
| CA2235762A1 (en) * | 1995-11-14 | 1997-05-22 | Genometrix Genomics, Inc. | Integrated nucleic acid hybridization devices based upon active surface chemistry |
| US6132765A (en) * | 1996-04-12 | 2000-10-17 | Uroteq Inc. | Drug delivery via therapeutic hydrogels |
| US6130037A (en) * | 1996-04-25 | 2000-10-10 | Pence And Mcgill University | Biosensor device and method |
| WO1997041425A1 (en) | 1996-04-25 | 1997-11-06 | Pence, Inc. | Biosensor device and method |
| US6485703B1 (en) * | 1998-07-31 | 2002-11-26 | The Texas A&M University System | Compositions and methods for analyte detection |
| JP3919958B2 (ja) * | 1998-11-11 | 2007-05-30 | 独立行政法人科学技術振興機構 | 高分子薄膜の製造方法 |
| ATE269114T1 (de) * | 1998-11-20 | 2004-07-15 | Univ Connecticut | Verfahren und vorrichtung zur steuerung der gewebeimplantat-interaktionen |
| US6413587B1 (en) * | 1999-03-02 | 2002-07-02 | International Business Machines Corporation | Method for forming polymer brush pattern on a substrate surface |
-
2000
- 2000-01-25 AT AT00909103T patent/ATE334226T1/de not_active IP Right Cessation
- 2000-01-25 US US09/889,935 patent/US7250253B1/en not_active Expired - Fee Related
- 2000-01-25 WO PCT/EP2000/000554 patent/WO2000043539A2/en not_active Ceased
- 2000-01-25 CA CA002360027A patent/CA2360027A1/en not_active Abandoned
- 2000-01-25 JP JP2000594947A patent/JP4970654B2/ja not_active Expired - Fee Related
- 2000-01-25 AU AU31504/00A patent/AU3150400A/en not_active Abandoned
- 2000-01-25 DE DE60029561T patent/DE60029561T2/de not_active Expired - Lifetime
- 2000-01-25 EP EP00909103A patent/EP1144677B1/en not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002535450A5 (https=) | ||
| Piletsky | Molecular imprinting of polymers | |
| Mosbach et al. | The emerging technique of molecular imprinting and its future impact on biotechnology | |
| EP1144677B1 (en) | Immobilization of molecules on surfaces via polymer brushes | |
| Li et al. | Molecular imprinting: A versatile tool for separation, sensors and catalysis | |
| JP2003520570A (ja) | 位置特定可能なアレイによるリガーゼ検出反応を用いた核酸配列差異の検出 | |
| EP1292637A1 (en) | Molecular imprinting | |
| CA2864908C (en) | Preparation of molecular imprinted polymers by cross-linking | |
| EP0743870A1 (en) | Preparation and application of artificial anti-idiotypic imprints | |
| Kugimiya et al. | Recognition of sialic acid using molecularly imprinted polymer | |
| JP2004506922A (ja) | バイオチップマイクロアレイを構築するための固体支持体の表面活性化を得る方法 | |
| Chiari et al. | Advanced polymers for molecular recognition and sensing at the interface | |
| EP1176423B1 (en) | Surface-attached polyfunctional polymer networks for sensor chips | |
| CN103626937B (zh) | 青霉素钠表面分子印迹聚合物的制备方法 | |
| JP2002541818A5 (https=) | ||
| CN101074950B (zh) | 凝胶芯片检测方法与检测装置 | |
| EP1035218A1 (en) | Immobilization of molecules on surfaces via polymer brushes | |
| Danielsson | Artificial receptors | |
| JP2001136968A (ja) | 生体高分子固定化フィルム積層体及びその薄片並びにそれらの製造方法 | |
| JP2024512158A (ja) | マイクロ流体デバイス上へのタンパク質共局在デバイス（ｐｃｄ）の組み込み | |
| CN110297084A (zh) | 一种生物芯片的抗体高效固定方法 | |
| CA3054137C (en) | Ligand bound mbp membranes, uses and method of manufacturing | |
| SE527299C2 (sv) | Molekylärt avtrycksmaterial framställt med fastfassyntesprodukter som mallar, dess framställning och användning |