JP2002541818A5 - - Google Patents
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- Publication number
- JP2002541818A5 JP2002541818A5 JP2000611713A JP2000611713A JP2002541818A5 JP 2002541818 A5 JP2002541818 A5 JP 2002541818A5 JP 2000611713 A JP2000611713 A JP 2000611713A JP 2000611713 A JP2000611713 A JP 2000611713A JP 2002541818 A5 JP2002541818 A5 JP 2002541818A5
- Authority
- JP
- Japan
- Prior art keywords
- phage
- biomolecule
- population
- bound
- collection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 description 30
- 102000004169 proteins and genes Human genes 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- 102000014914 Carrier Proteins Human genes 0.000 description 9
- 108091008324 binding proteins Proteins 0.000 description 9
- 239000012472 biological sample Substances 0.000 description 7
- 102000039446 nucleic acids Human genes 0.000 description 7
- 108020004707 nucleic acids Proteins 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 238000001962 electrophoresis Methods 0.000 description 5
- 230000001580 bacterial effect Effects 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 108090001008 Avidin Proteins 0.000 description 3
- 108010090804 Streptavidin Proteins 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- 230000009089 cytolysis Effects 0.000 description 2
- 102000040430 polynucleotide Human genes 0.000 description 2
- 108091033319 polynucleotide Proteins 0.000 description 2
- 239000002157 polynucleotide Substances 0.000 description 2
- 238000009007 Diagnostic Kit Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 239000012504 chromatography matrix Substances 0.000 description 1
- 239000012539 chromatography resin Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12921599P | 1999-04-14 | 1999-04-14 | |
| US60/129,215 | 1999-04-14 | ||
| PCT/US2000/010146 WO2000061790A1 (en) | 1999-04-14 | 2000-04-13 | High sensitivity phage display biomolecule detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002541818A JP2002541818A (ja) | 2002-12-10 |
| JP2002541818A5 true JP2002541818A5 (https=) | 2007-01-11 |
Family
ID=22438929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000611713A Withdrawn JP2002541818A (ja) | 1999-04-14 | 2000-04-13 | 高感度ファージ提示生体分子検出 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6740492B2 (https=) |
| EP (1) | EP1169473B1 (https=) |
| JP (1) | JP2002541818A (https=) |
| AT (1) | ATE346162T1 (https=) |
| AU (1) | AU778776B2 (https=) |
| CA (1) | CA2368875A1 (https=) |
| DE (1) | DE60031965D1 (https=) |
| WO (1) | WO2000061790A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2360282A (en) * | 2000-03-17 | 2001-09-19 | Bioinvent Int Ab | Making and using micro-arrays of biological materials |
| WO2003010198A1 (en) * | 2001-07-26 | 2003-02-06 | Kenton Srl | Identification of specific tumour antigens by selection of cdna libraries with sera and use of said antigens in diagnostic techniques |
| WO2003011902A1 (en) * | 2001-07-27 | 2003-02-13 | Kenton S.R.L. | Identification of specific tumour antigens by selection of cdna libraries with sera |
| MXPA05002934A (es) * | 2002-09-18 | 2006-02-24 | Univ Pennsylvania | Composiciones, metodos y kits para deteccion de un antigeno en una celula y en una mezcla biologica. |
| GB0304832D0 (en) * | 2003-03-04 | 2003-04-09 | Secr Defence | Assay method |
| US8173002B2 (en) * | 2005-02-24 | 2012-05-08 | Life Technologies Corporation | Electro-blotting devices, systems, and kits, and methods for their use |
| EP1885853A2 (en) | 2005-05-27 | 2008-02-13 | Guild Associates, Inc. | Biological detection system and method |
| US8066866B2 (en) * | 2005-10-17 | 2011-11-29 | Lifescan, Inc. | Methods for measuring physiological fluids |
| EP1963494B1 (en) * | 2005-11-29 | 2014-10-08 | The Trustees of The University of Pennsylvania | Phage particle diagnostic reagents |
| US20100044229A1 (en) * | 2008-07-11 | 2010-02-25 | Life Technologies Corporation | Electrophoretically Enhanced Detection of Analytes on a Solid Support |
| USD738527S1 (en) | 2013-05-28 | 2015-09-08 | Life Technologies Corporation | Electroblotting apparatus |
| TWI570243B (zh) | 2015-11-03 | 2017-02-11 | 國立清華大學 | 噬菌體之篩選裝置及方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| GB9104411D0 (en) * | 1991-03-01 | 1991-04-17 | Elchrom Limited | Improvement of gel composition in gels for submerged gel electrophoresis |
| BE1006312A3 (fr) * | 1991-11-29 | 1994-07-19 | Univ Catholique Louvain | Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique. |
| US5650267A (en) * | 1993-04-27 | 1997-07-22 | Symbiotech, Inc. | Method of detecting compounds utilizing genetically modified lambdoid bacteriophage |
| US5679510A (en) * | 1993-04-27 | 1997-10-21 | Hybridon, Inc. | Quantitative detection of specific nucleic acid sequences using lambdoid bacteriophages linked by oligonucleotides to solid support |
| US6027877A (en) * | 1993-11-04 | 2000-02-22 | Gene Check, Inc. | Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification |
| US5702892A (en) * | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
| IL114149A0 (en) * | 1995-06-14 | 1995-10-31 | Yeda Res & Dev | Modified avidin and streptavidin molecules and use thereof |
| WO1997022972A2 (en) * | 1995-12-15 | 1997-06-26 | Pharmacia & Upjohn Company | Method for the simultaneous detection of a therapeutic target for a disease state and its neutralizing antibody-like molecule |
| EP0934526B1 (en) * | 1996-10-08 | 2003-01-08 | U-BISys B.V. | Methods and means for selecting peptides and proteins having specific affinity for a target |
-
2000
- 2000-04-13 EP EP00926011A patent/EP1169473B1/en not_active Expired - Lifetime
- 2000-04-13 AU AU44612/00A patent/AU778776B2/en not_active Ceased
- 2000-04-13 WO PCT/US2000/010146 patent/WO2000061790A1/en not_active Ceased
- 2000-04-13 DE DE60031965T patent/DE60031965D1/de not_active Expired - Lifetime
- 2000-04-13 CA CA002368875A patent/CA2368875A1/en not_active Abandoned
- 2000-04-13 JP JP2000611713A patent/JP2002541818A/ja not_active Withdrawn
- 2000-04-13 AT AT00926011T patent/ATE346162T1/de not_active IP Right Cessation
-
2001
- 2001-10-10 US US09/976,667 patent/US6740492B2/en not_active Expired - Fee Related
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