JP2002535357A - ｐ５３阻害剤およびその治療用途 - Google Patents
ｐ５３阻害剤およびその治療用途Info
- Publication number
- JP2002535357A JP2002535357A JP2000595668A JP2000595668A JP2002535357A JP 2002535357 A JP2002535357 A JP 2002535357A JP 2000595668 A JP2000595668 A JP 2000595668A JP 2000595668 A JP2000595668 A JP 2000595668A JP 2002535357 A JP2002535357 A JP 2002535357A
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- alkyl
- aryl
- group
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11788199P | 1999-01-29 | 1999-01-29 | |
| US60/117,881 | 1999-01-29 | ||
| PCT/US2000/002104 WO2000044364A2 (en) | 1999-01-29 | 2000-01-28 | P53 inhibitors and their use for the treatment of cancer, hyperthermia, hypoxia, a burn, trauma to the central nervous system, a seizure, acute inflammation, tissue ageing, preservation of organs for transplant and preparation of a host for bone marrow transplant |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010185868A Division JP2010265321A (ja) | 1999-01-29 | 2010-08-23 | ｐ５３阻害剤およびその治療用途 |
Publications (1)
| Publication Number | Publication Date |
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Family
ID=22375329
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000595668A Pending JP2002535357A (ja) | 1999-01-29 | 2000-01-28 | ｐ５３阻害剤およびその治療用途 |
| JP2010185868A Pending JP2010265321A (ja) | 1999-01-29 | 2010-08-23 | ｐ５３阻害剤およびその治療用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010185868A Pending JP2010265321A (ja) | 1999-01-29 | 2010-08-23 | ｐ５３阻害剤およびその治療用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US6593353B1 (https=) |
| EP (1) | EP1143943B1 (https=) |
| JP (2) | JP2002535357A (https=) |
| AT (1) | ATE380548T1 (https=) |
| AU (1) | AU3584200A (https=) |
| CA (1) | CA2360671A1 (https=) |
| DE (1) | DE60037394T2 (https=) |
| IL (3) | IL144294A0 (https=) |
| NZ (1) | NZ513487A (https=) |
| WO (1) | WO2000044364A2 (https=) |
| ZA (1) | ZA200105823B (https=) |
Cited By (2)
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| WO2008072655A1 (ja) * | 2006-12-14 | 2008-06-19 | Daiichi Sankyo Company, Limited | イミダゾチアゾール誘導体 |
| JP2021024852A (ja) * | 2019-08-01 | 2021-02-22 | 東京都公立大学法人 | 機能不全ミトコンドリアを消去するための複合体、および細胞老化を抑制するための複合体 |
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| WO2002014321A1 (en) * | 2000-08-11 | 2002-02-21 | The Regents Of The University Of California | Use of stat-6 inhibitors as therapeutic agents |
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| US6861431B2 (en) | 2001-03-23 | 2005-03-01 | The Board Of Trustees Of The University Of Illinois | Compounds capable of modulating the activity of multidrug transporters and therapeutic use of the same |
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| US20070110756A1 (en) * | 2005-11-14 | 2007-05-17 | Reinberg Danny F | Method for modulating P53 activity via methylation |
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| JPH06506666A (ja) * | 1990-11-07 | 1994-07-28 | アミラ・インコーポレーテツド | プリン代謝酵素の活性が増加している細胞の形質転換、増殖および転移を阻止する方法 |
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2000
- 2000-01-28 IL IL14429400A patent/IL144294A0/xx unknown
- 2000-01-28 NZ NZ513487A patent/NZ513487A/xx unknown
- 2000-01-28 WO PCT/US2000/002104 patent/WO2000044364A2/en not_active Ceased
- 2000-01-28 US US09/493,527 patent/US6593353B1/en not_active Expired - Lifetime
- 2000-01-28 DE DE60037394T patent/DE60037394T2/de not_active Expired - Lifetime
- 2000-01-28 EP EP00914455A patent/EP1143943B1/en not_active Revoked
- 2000-01-28 AU AU35842/00A patent/AU3584200A/en not_active Abandoned
- 2000-01-28 AT AT00914455T patent/ATE380548T1/de not_active IP Right Cessation
- 2000-01-28 CA CA002360671A patent/CA2360671A1/en not_active Abandoned
- 2000-01-28 JP JP2000595668A patent/JP2002535357A/ja active Pending
-
2001
- 2001-06-13 US US09/880,417 patent/US7012087B2/en not_active Expired - Lifetime
- 2001-07-12 IL IL144294A patent/IL144294A/en not_active IP Right Cessation
- 2001-07-16 ZA ZA200105823A patent/ZA200105823B/en unknown
- 2001-09-06 US US09/947,757 patent/US20020019425A1/en not_active Abandoned
-
2003
- 2003-01-24 US US10/350,560 patent/US6982277B2/en not_active Expired - Lifetime
- 2003-01-28 US US10/352,597 patent/US7008956B2/en not_active Expired - Lifetime
-
2005
- 2005-05-24 US US11/136,231 patent/US20050222224A1/en not_active Abandoned
-
2008
- 2008-01-30 US US12/022,317 patent/US20080161426A1/en not_active Abandoned
- 2008-12-04 IL IL195723A patent/IL195723A/en not_active IP Right Cessation
-
2010
- 2010-08-23 JP JP2010185868A patent/JP2010265321A/ja active Pending
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008072655A1 (ja) * | 2006-12-14 | 2008-06-19 | Daiichi Sankyo Company, Limited | イミダゾチアゾール誘導体 |
| JP2021024852A (ja) * | 2019-08-01 | 2021-02-22 | 東京都公立大学法人 | 機能不全ミトコンドリアを消去するための複合体、および細胞老化を抑制するための複合体 |
| JP7429035B2 (ja) | 2019-08-01 | 2024-02-07 | 東京都公立大学法人 | 機能不全ミトコンドリアを消去するための複合体、および細胞老化を抑制するための複合体 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20030144331A1 (en) | 2003-07-31 |
| US6593353B1 (en) | 2003-07-15 |
| NZ513487A (en) | 2003-02-28 |
| JP2010265321A (ja) | 2010-11-25 |
| EP1143943A2 (en) | 2001-10-17 |
| IL144294A (en) | 2010-04-15 |
| EP1143943A3 (en) | 2002-09-11 |
| WO2000044364A2 (en) | 2000-08-03 |
| DE60037394T2 (de) | 2009-01-02 |
| US7012087B2 (en) | 2006-03-14 |
| AU3584200A (en) | 2000-08-18 |
| US20020006941A1 (en) | 2002-01-17 |
| US7008956B2 (en) | 2006-03-07 |
| IL144294A0 (en) | 2002-05-23 |
| ATE380548T1 (de) | 2007-12-15 |
| CA2360671A1 (en) | 2000-08-03 |
| US20080161426A1 (en) | 2008-07-03 |
| EP1143943B1 (en) | 2007-12-12 |
| US20030176318A1 (en) | 2003-09-18 |
| ZA200105823B (en) | 2002-05-07 |
| US20050222224A1 (en) | 2005-10-06 |
| WO2000044364A3 (en) | 2001-08-23 |
| IL195723A (en) | 2010-12-30 |
| US20020019425A1 (en) | 2002-02-14 |
| DE60037394D1 (de) | 2008-01-24 |
| US6982277B2 (en) | 2006-01-03 |
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