JP2002526028A5 - - Google Patents

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Publication number
JP2002526028A5
JP2002526028A5 JP2000517077A JP2000517077A JP2002526028A5 JP 2002526028 A5 JP2002526028 A5 JP 2002526028A5 JP 2000517077 A JP2000517077 A JP 2000517077A JP 2000517077 A JP2000517077 A JP 2000517077A JP 2002526028 A5 JP2002526028 A5 JP 2002526028A5
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JP
Japan
Prior art keywords
polypeptide
amino acid
dna
seq
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000517077A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002526028A (ja
JP4319348B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/021141 external-priority patent/WO1999020756A2/en
Publication of JP2002526028A publication Critical patent/JP2002526028A/ja
Publication of JP2002526028A5 publication Critical patent/JP2002526028A5/ja
Application granted granted Critical
Publication of JP4319348B2 publication Critical patent/JP4319348B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2000517077A 1997-10-17 1998-10-07 ヒトトール相同体 Expired - Lifetime JP4319348B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US6225097P 1997-10-17 1997-10-17
US60/062,250 1997-10-17
US6531197P 1997-11-13 1997-11-13
US60/065,311 1997-11-13
US8332298P 1998-04-28 1998-04-28
US60/083,322 1998-04-28
US9086398P 1998-06-26 1998-06-26
US10541398A 1998-06-26 1998-06-26
US60/090,863 1998-06-26
US09/105,413 1998-06-26
PCT/US1998/021141 WO1999020756A2 (en) 1997-10-17 1998-10-07 Human toll homologues

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008328570A Division JP5027105B2 (ja) 1997-10-17 2008-12-24 ヒトトール相同体

Publications (3)

Publication Number Publication Date
JP2002526028A JP2002526028A (ja) 2002-08-20
JP2002526028A5 true JP2002526028A5 (https=) 2006-02-16
JP4319348B2 JP4319348B2 (ja) 2009-08-26

Family

ID=27535565

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000517077A Expired - Lifetime JP4319348B2 (ja) 1997-10-17 1998-10-07 ヒトトール相同体
JP2008328570A Expired - Lifetime JP5027105B2 (ja) 1997-10-17 2008-12-24 ヒトトール相同体
JP2012017737A Expired - Lifetime JP5425244B2 (ja) 1997-10-17 2012-01-31 ヒトトール相同体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2008328570A Expired - Lifetime JP5027105B2 (ja) 1997-10-17 2008-12-24 ヒトトール相同体
JP2012017737A Expired - Lifetime JP5425244B2 (ja) 1997-10-17 2012-01-31 ヒトトール相同体

Country Status (11)

Country Link
EP (3) EP1025227B1 (https=)
JP (3) JP4319348B2 (https=)
AT (3) ATE381574T1 (https=)
AU (1) AU1070399A (https=)
CA (1) CA2305385C (https=)
DE (3) DE69838888T2 (https=)
DK (3) DK1025227T3 (https=)
ES (2) ES2298905T3 (https=)
IL (4) IL135345A0 (https=)
PT (2) PT1887014E (https=)
WO (1) WO1999020756A2 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7696327B1 (en) 1997-10-17 2010-04-13 Genentech, Inc. Antibodies to human Toll homologues
US20030032090A1 (en) 1997-05-07 2003-02-13 Schering Corporation, A New Jersey Corporation Human receptor proteins; related reagents and methods
AU2001264889B2 (en) * 1997-05-07 2006-06-29 Schering Corporation Human receptor proteins; related reagents and methods
ES2331622T3 (es) * 1997-05-07 2010-01-11 Schering Corporation Proteinas receptoras humanas similares a toll, reactivos y metodos relacionados.
US6303321B1 (en) 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
NZ534666A (en) * 2000-05-25 2006-01-27 Schering Corp Mammalian DNAX Toll-like receptor protein, DTLR9, antibodies and medicaments made therefrom and use in treating immunological disorders
JP2005500806A (ja) 2000-09-15 2005-01-13 コーリー ファーマシューティカル ゲーエムベーハー ＣｐＧに基づく免疫アゴニスト／免疫アンタゴニストの高スループットスクリーニングのためのプロセス
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
US7304034B2 (en) 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
EP1293566A1 (en) * 2001-09-17 2003-03-19 Societe Des Produits Nestle S.A. A soluble toll-like receptor
US20060058288A1 (en) * 2002-04-08 2006-03-16 Masayuki Ii Severe sepsis preventive therapeutic agent
US8183350B2 (en) 2002-05-04 2012-05-22 Acorda Therapeutics, Inc. Compositions and methods for promoting neuronal outgrowth
CA2505843A1 (en) 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
EP1567863A4 (en) * 2002-11-22 2007-10-03 Nuvelo Inc THERAPY AND DIAGNOSTIC PROCEDURES
EP1631687A2 (en) * 2003-04-22 2006-03-08 Coley Pharmaceutical GmbH Methods and products for identification and assessment of tlr ligands
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
EP3211084B1 (en) * 2003-05-16 2019-03-27 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of cns
US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
WO2005001116A1 (ja) * 2003-06-17 2005-01-06 Meiji Dairies Corporation Toll様レセプター強制発現細胞の利用
JP4562123B2 (ja) * 2003-06-17 2010-10-13 明治乳業株式会社 Ｔｏｌｌ様レセプター強制発現細胞の利用
AU2004272607B2 (en) 2003-09-11 2008-11-06 Cornerstone Therapeutics Inc. Monoclonal antibodies against HMGB1
MXPA06013345A (es) 2004-05-18 2008-10-31 Acorda Therapeutics Inc Metodos para purificar condrointinasa y sus formulaciones estables.
DK1773872T3 (en) * 2004-05-21 2017-05-08 Uab Res Found VARIABLE Lymphocyte Receptors, Associated Polypeptides and Nucleic Acids, and Uses thereof
JP2008538007A (ja) 2005-04-15 2008-10-02 ベクトン，ディッキンソン アンド カンパニー 敗血症の診断
JP5189985B2 (ja) 2005-09-26 2013-04-24 アコーダ セラピューティクス、インク． コンドロイチナーゼａｂｃｉ変異体を用いた組成物およびその使用方法
EP1945820B1 (en) * 2005-10-27 2013-08-28 Janssen Biotech, Inc. Toll like receptor 3 modulators, methods and uses
CA2649387A1 (en) * 2006-04-19 2008-03-27 Genentech, Inc. Novel gene disruptions, compositions and methods relating thereto
CA3009034C (en) 2006-10-10 2020-08-18 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
US8669113B2 (en) 2008-04-03 2014-03-11 Becton, Dickinson And Company Advanced detection of sepsis
TWI481401B (zh) 2010-01-27 2015-04-21 Takeda Pharmaceutical 藥劑
CN117534753B (zh) * 2023-12-07 2024-05-10 北京博奥森生物技术有限公司 一种诱导高性能NF-κB多克隆抗体多肽及其应用

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
DE3850542T2 (de) 1987-09-23 1994-11-24 Bristol Myers Squibb Co Antikörper-Heterokonjugate zur Töting von HIV-infizierten Zellen.
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
ES2096590T3 (es) 1989-06-29 1997-03-16 Medarex Inc Reactivos biespecificos para la terapia del sida.
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
ATE158021T1 (de) 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
WO1992020373A1 (en) 1991-05-14 1992-11-26 Repligen Corporation Heteroconjugate antibodies for treatment of hiv infection
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
ES2331622T3 (es) * 1997-05-07 2010-01-11 Schering Corporation Proteinas receptoras humanas similares a toll, reactivos y metodos relacionados.
ES2263865T3 (es) * 1998-03-25 2006-12-16 Genentech, Inc. Homologo humano de neurotrimina.

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