JP2003534013A5 - - Google Patents
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- Publication number
- JP2003534013A5 JP2003534013A5 JP2001587152A JP2001587152A JP2003534013A5 JP 2003534013 A5 JP2003534013 A5 JP 2003534013A5 JP 2001587152 A JP2001587152 A JP 2001587152A JP 2001587152 A JP2001587152 A JP 2001587152A JP 2003534013 A5 JP2003534013 A5 JP 2003534013A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- dcrs9
- seq
- recombinant
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 description 27
- 229920001184 polypeptide Polymers 0.000 description 26
- 102000004196 processed proteins & peptides Human genes 0.000 description 26
- 102000039446 nucleic acids Human genes 0.000 description 14
- 108020004707 nucleic acids Proteins 0.000 description 14
- 150000007523 nucleic acids Chemical class 0.000 description 14
- 150000001875 compounds Chemical class 0.000 description 11
- 210000004027 cell Anatomy 0.000 description 9
- 238000000034 method Methods 0.000 description 7
- 150000001413 amino acids Chemical class 0.000 description 6
- 239000000427 antigen Substances 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 4
- 108091007433 antigens Proteins 0.000 description 4
- 241000288906 Primates Species 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 239000005557 antagonist Substances 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000007911 parenteral administration Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 238000011200 topical administration Methods 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 description 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 description 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 description 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 102000003675 cytokine receptors Human genes 0.000 description 1
- 108010057085 cytokine receptors Proteins 0.000 description 1
- 210000003527 eukaryotic cell Anatomy 0.000 description 1
- 239000013604 expression vector Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 210000004962 mammalian cell Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 210000001236 prokaryotic cell Anatomy 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20686200P | 2000-05-24 | 2000-05-24 | |
| US60/206,862 | 2000-05-24 | ||
| PCT/US2001/016767 WO2001090358A2 (en) | 2000-05-24 | 2001-05-23 | Mammalian receptor proteins; related reagents and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003534013A JP2003534013A (ja) | 2003-11-18 |
| JP2003534013A5 true JP2003534013A5 (https=) | 2008-07-10 |
Family
ID=22768279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001587152A Pending JP2003534013A (ja) | 2000-05-24 | 2001-05-23 | 哺乳動物レセプタータンパク質；関連試薬および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20030092881A1 (https=) |
| EP (1) | EP1303604A2 (https=) |
| JP (1) | JP2003534013A (https=) |
| CN (1) | CN1444652A (https=) |
| AU (1) | AU2001274920A1 (https=) |
| CA (1) | CA2410083A1 (https=) |
| MX (1) | MXPA02011617A (https=) |
| WO (1) | WO2001090358A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU740405B2 (en) | 1998-05-15 | 2001-11-01 | Genentech Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
| DK1897945T3 (da) * | 1999-12-23 | 2012-05-07 | Genentech Inc | IL-17 homologe polypeptider og terapeutiske anvendelser deraf. |
| US20040043397A1 (en) | 2000-01-11 | 2004-03-04 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| EP1266002A2 (en) * | 2000-03-16 | 2002-12-18 | Amgen Inc., | Il-17 receptor like molecules and uses thereof |
| US7094566B2 (en) | 2000-03-16 | 2006-08-22 | Amgen Inc., | IL-17 receptor like molecules and uses thereof |
| US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
| US20040197306A1 (en) * | 2000-05-24 | 2004-10-07 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
| US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| AU2001271860A1 (en) * | 2000-07-06 | 2002-01-21 | Zymogenetics Inc. | Murine cytokine receptor |
| EP1529843A3 (en) * | 2000-08-11 | 2005-06-08 | Eli Lilly & Company | Novel secreted proteins and their uses |
| WO2002038764A2 (en) * | 2000-11-10 | 2002-05-16 | The Regents Of The University Of California | Il-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage |
| WO2004004649A2 (en) * | 2002-07-08 | 2004-01-15 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US20060281146A1 (en) * | 2002-09-11 | 2006-12-14 | Genetech, Inc. | Novel compositions and methods for the treatment of immune related diseases |
| EP2784084B2 (en) | 2003-07-08 | 2023-10-04 | Novartis Pharma AG | Antagonist antibodies to IL-17A/F heterologous polypeptides |
| US7910540B2 (en) * | 2004-06-10 | 2011-03-22 | Zymogenetics, Inc. | Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation |
| AU2005295421A1 (en) * | 2004-10-18 | 2006-04-27 | Zymogenetics, Inc. | Soluble Zcytor21, anti-Zcytor21 antibodies and binding partners and methods of using in inflammation |
| US20060147945A1 (en) * | 2005-01-06 | 2006-07-06 | Edmonds Brian T | Novel secreted proteins and their uses |
| US20070249533A1 (en) * | 2005-09-28 | 2007-10-25 | Levin Steven D | Il-17a and il-17f antagonists and methods of using the same |
| JP2009510093A (ja) * | 2005-09-28 | 2009-03-12 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−１７ａおよびｉｌ−１７ｆアンタゴニストならびにその使用方法 |
| WO2008039553A1 (en) * | 2006-02-10 | 2008-04-03 | Zymogenetics, Inc. | Soluble il-17rcx4 and methods of using in inflammation |
| US7790676B2 (en) | 2007-03-28 | 2010-09-07 | Zymogenetics, Inc. | Soluble IL-17RA/RC fusion proteins |
| RU2474588C2 (ru) | 2008-05-05 | 2013-02-10 | Новиммун Са | Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения |
| CN102458437B (zh) | 2009-05-05 | 2015-06-10 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
| US9611295B2 (en) * | 2011-10-27 | 2017-04-04 | The Cleveland Clinic Foundation | Treatment of IL-17 mediated disease by blocking SEFIR-SEFIR interactions |
| CA2901231C (en) * | 2013-02-15 | 2020-06-23 | Thomas Jefferson University | Kit comprising lyophilized compositions for tumor imaging |
| CN106794194A (zh) * | 2014-06-30 | 2017-05-31 | 中央研究院 | 用于癌症治疗的介白素‑17受体b（il‑17rb）及其配体il‑17b之拮抗剂 |
| KR20230046316A (ko) * | 2020-08-07 | 2023-04-05 | 아토스 테라퓨틱스, 인크. | 후보 치료제를 스크리닝하기 위한 멀티-오믹 시그니처를 평가하기 위한 생체외 위장관 생검 플랫폼 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ306653A (en) * | 1995-03-23 | 1999-03-29 | Immunex Corp | Isolated dna il-17 receptors |
| ES2333385T3 (es) * | 1997-09-17 | 2010-02-19 | Human Genome Sciences, Inc. | Proteina del tipo de interleuquina-17. |
| WO1999055865A1 (en) * | 1998-04-29 | 1999-11-04 | Genesis Research And Development Corporation Limited | Polynucleotides isolated from skin cells and methods for their use |
| US6150502A (en) * | 1998-04-29 | 2000-11-21 | Genesis Research & Development Corporation Limited | Polypeptides expressed in skin cells |
| ES2380812T3 (es) * | 1999-12-23 | 2012-05-18 | Genentech, Inc. | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
| EP1266002A2 (en) * | 2000-03-16 | 2002-12-18 | Amgen Inc., | Il-17 receptor like molecules and uses thereof |
| US20040197306A1 (en) * | 2000-05-24 | 2004-10-07 | Gorman Daniel M. | Mammalian receptor proteins; related reagents and methods |
-
2001
- 2001-05-23 US US09/863,818 patent/US20030092881A1/en not_active Abandoned
- 2001-05-23 EP EP01941579A patent/EP1303604A2/en not_active Withdrawn
- 2001-05-23 WO PCT/US2001/016767 patent/WO2001090358A2/en not_active Ceased
- 2001-05-23 CA CA002410083A patent/CA2410083A1/en not_active Abandoned
- 2001-05-23 JP JP2001587152A patent/JP2003534013A/ja active Pending
- 2001-05-23 AU AU2001274920A patent/AU2001274920A1/en not_active Abandoned
- 2001-05-23 CN CN01813327A patent/CN1444652A/zh active Pending
- 2001-05-23 MX MXPA02011617A patent/MXPA02011617A/es not_active Application Discontinuation
-
2004
- 2004-08-23 US US10/924,667 patent/US20050009145A1/en not_active Abandoned
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