JP2002513411A - 高いバイオアベイラビリティを有するルテインエステル - Google Patents

高いバイオアベイラビリティを有するルテインエステル

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Publication number
JP2002513411A
JP2002513411A JP54285098A JP54285098A JP2002513411A JP 2002513411 A JP2002513411 A JP 2002513411A JP 54285098 A JP54285098 A JP 54285098A JP 54285098 A JP54285098 A JP 54285098A JP 2002513411 A JP2002513411 A JP 2002513411A
Authority
JP
Japan
Prior art keywords
composition
weight
lutein
lutein ester
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP54285098A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002513411A5 (https=
Inventor
ボーウェン，フィリス，イー．
クラーク，ジェイムス，ピー．
Original Assignee
ヘンケル コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ヘンケル コーポレーション filed Critical ヘンケル コーポレーション
Publication of JP2002513411A publication Critical patent/JP2002513411A/ja
Publication of JP2002513411A5 publication Critical patent/JP2002513411A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP54285098A 1997-04-04 1998-04-03 高いバイオアベイラビリティを有するルテインエステル Ceased JP2002513411A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4269797P 1997-04-04 1997-04-04
US60/042,697 1997-04-04
US5434698A 1998-04-02 1998-04-02
US09/054,346 1998-04-02
PCT/US1998/006278 WO1998045241A2 (en) 1997-04-04 1998-04-03 Lutein esters having high bioavailability

Publications (2)

Publication Number Publication Date
JP2002513411A true JP2002513411A (ja) 2002-05-08
JP2002513411A5 JP2002513411A5 (https=) 2005-11-24

Family

ID=26719527

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54285098A Ceased JP2002513411A (ja) 1997-04-04 1998-04-03 高いバイオアベイラビリティを有するルテインエステル

Country Status (5)

Country Link
US (1) US6313169B1 (https=)
EP (1) EP0984915A4 (https=)
JP (1) JP2002513411A (https=)
AU (1) AU752468B2 (https=)
WO (1) WO1998045241A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517197A (ja) * 2002-07-29 2006-07-20 ハワイ バイオテック， インコーポレイテッド 病気の抑制と改善のための構造上のカロチノイド類似体
WO2008099469A1 (ja) * 2007-02-14 2008-08-21 Tohoku University 赤血球の脂質過酸化を抑制するための組成物および方法
JP2009513641A (ja) * 2005-10-26 2009-04-02 アボット・ラボラトリーズ ドコサヘキサエン酸およびルテインを含有する乳児用製剤
US8263147B2 (en) 2005-10-26 2012-09-11 Abbott Laboratories Infant formulas containing docosahexaenoic acid and lutein

Families Citing this family (34)

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US6191293B1 (en) 1998-04-20 2001-02-20 Inexa, Industria Extractora C.A. Trans-xanthophyll ester concentrates of enhanced purity and methods of making same
NL1010351C2 (nl) * 1998-10-19 2001-01-08 Werklust & Beheer B V Esters van caroteno´den voor gebruik in de preventie en behandeling van oogaandoeningen.
US7078040B2 (en) 2000-03-27 2006-07-18 Fuji Chemical Industry Co., Ltd. Method of inhibiting the expression of inflammatory cytokines and chemokines
SE0001071D0 (sv) * 2000-03-27 2000-03-27 Astacarotene Ab Method of inhibiting the expression of inflammatory cytokines and chemokines
BR0207405B1 (pt) * 2001-02-23 2012-09-18 novos ésteres carotenóides.
US6784351B2 (en) * 2001-06-29 2004-08-31 Ball Horticultural Company Targetes erecta marigolds with altered carotenoid compositions and ratios
US6811801B2 (en) 2001-12-12 2004-11-02 Abbott Laboratories Methods and compositions for brightening the color of thermally processed nutritionals
JP2003201497A (ja) * 2002-01-08 2003-07-18 Riken Vitamin Co Ltd ルテイン脂肪酸エステル濃縮物の製造方法
US6737535B2 (en) 2002-06-05 2004-05-18 Kancor Flavours And Extracts Limited Trans-lutein enriched xanthophyll ester concentrate and a process for its preparation
US7345091B2 (en) 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US20050059635A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling C-reactive protein levels
US7763649B2 (en) 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US7723327B2 (en) 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US7320997B2 (en) 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US6743953B2 (en) 2002-08-26 2004-06-01 Kancor Flavours & Extracts Ltd. Process for the preparation of xanthophyll crystals
WO2005025586A1 (en) 2003-09-12 2005-03-24 Access Business Group International Llc Cytokine modulators and related method of use
PE20050398A1 (es) * 2003-09-22 2005-06-03 Rosales Jose Antonio Socla Proceso y purificacion de las xantofilas de marigold
US7446101B1 (en) 2003-12-12 2008-11-04 Bioactives, Llc Bioavailable carotenoid-cyclodextrin formulations for soft-gels and other encapsulation systems
EP1750723A1 (en) * 2004-04-14 2007-02-14 Hawaii Biotech, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US20060018842A1 (en) * 2004-06-25 2006-01-26 Gary Blumenthal Composition and method for delivery of phytochemicals
US7351424B2 (en) 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
US20060024247A1 (en) * 2004-07-28 2006-02-02 Bioactives, Llc Oral care formulations comprising highly bioavailable Coenzyme Q-10 cyclodextrin complex
US20070065487A1 (en) * 2005-09-21 2007-03-22 Bio Lut S.A. De C.V. Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof
AT503329A1 (de) 2006-03-02 2007-09-15 Omnica Gmbh Verfahren zur herstellung einer zusammensetzung, welche zumindest ein xantophyll enthält
WO2008023283A2 (en) * 2006-08-25 2008-02-28 Omnica Gmbh Stabilized esters of lutein
DE102017009186A1 (de) 2017-09-25 2019-03-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Lutein und -derivate enthaltende Zusammensetzung sowie Verfahren zur Herstellung
US11089954B2 (en) 2018-09-21 2021-08-17 MacuLogix, Inc. Method and apparatus for guiding a test subject through an ophthalmic test
CN112402593A (zh) * 2020-10-22 2021-02-26 宁波君瑞生物科技有限公司 一种缓解运动膝关节不适的凝胶制剂

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US2527602A (en) 1947-07-29 1950-10-31 Monroe E Wall Process of separating carotene fractions and tocopherol-sterol fractions from green plant materials
CH420822A (de) 1960-10-17 1966-09-15 Hoffmann La Roche Wasserdispergierbare Carotinoidzubereitung
US3523138A (en) 1965-03-01 1970-08-04 Eastman Kodak Co Treatment of marigold petal meal to obtain a xanthophyll product
US3558712A (en) 1967-02-23 1971-01-26 Hoffmann La Roche Method for the synthesis of zeaxanthins,xanthophylis,and 3-oxo-beta carotene
US3661997A (en) 1967-02-23 1972-05-09 Hoffmann La Roche Mono-oxo carotenes
US3989757A (en) 1973-08-29 1976-11-02 Hoffmann-La Roche Inc. Isomerizing cis-carotenoids to all-trans-carotenoids
US3997679A (en) 1974-08-12 1976-12-14 Cpc International Inc. Stabilization of xanthophylls
US4048203A (en) 1976-12-06 1977-09-13 Thomas Philip Purification of lutein-fatty acid esters from plant materials
US4851339A (en) 1986-04-01 1989-07-25 Hills Christopher B Extraction of anti-mutagenic pigments from algae and vegetables
IL88961A (en) 1988-01-29 1992-07-15 Basf Ag Stable mixtures containing oxidation-sensitive compounds
US5019668A (en) 1988-06-14 1991-05-28 Palm Oil Research & Development Board Recovery of carotenoids
US5180747A (en) 1989-02-28 1993-01-19 Nisshin Flour Milling Co., Ltd. Stabilized fat-soluble vitamin compositions
US5290605A (en) 1989-06-29 1994-03-01 Niva Shapira Sun-exposure nutritional supporting composition
US5157132A (en) 1990-05-18 1992-10-20 Carotech Associates Integrated process for recovery of carotenoids and tocotrienols from oil
MC2309A1 (fr) 1990-10-01 1993-09-27 Brigham & Womens Hospital Traitement a base de beta-carotene et de vitamines pour inhiber les accidents vasculaires majeurs
DE69232376T2 (de) 1991-09-06 2002-09-26 Cognis Australien Pty.Ltd., Victoria Carotinoide zusammensetzung
GB9219524D0 (en) 1992-09-15 1992-10-28 Smithkline Beecham Plc Novel composition
DE19609538A1 (de) 1996-03-11 1997-09-18 Basf Ag Feinverteilte Carotinoid- und Retinoidsuspensionen und Verfahren zu ihrer Herstellung
EP0689427B1 (en) 1993-03-22 2002-06-12 Cognis Australia Pty Ltd Water dispersible therapeutic carotenoid compounds
DE69424537T2 (de) 1993-03-22 2001-11-15 Cognis Australien Pty.Ltd., Victoria Therapeutischer wirkstoff zur behandlung von melanomen
IL110139A0 (en) * 1993-06-28 1994-10-07 Howard Foundation Pharmaceutically-active antioxidants
US5382714A (en) 1994-03-17 1995-01-17 The Catholic University Of America Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof
AUPM493194A0 (en) 1994-04-08 1994-05-05 Buckmeier, Julie A. Therapeutic agent for inhibiting the conversion of epithelial cells to tumours
US5523494A (en) 1994-07-20 1996-06-04 Industrial Organica, S.A. De C.V. Process for the isomerization of lutein
WO1996023489A2 (de) 1995-02-03 1996-08-08 Basf Aktiengesellschaft Verwendung von carotinoiden zur herstellung von arzneimitteln zur behandlung von dermatosen
US5643623A (en) 1995-06-07 1997-07-01 Mars Incorporated Health food product and its uses
US5602286A (en) 1995-06-07 1997-02-11 Cargill, Incorporated Process for recovering xanthophylls from corn gluten
FR2735364B1 (fr) 1995-06-16 1997-08-01 Oreal Composition cosmetique ou dermatologique a liberation controlee d'actif contenant un carotenoide photoconvertible
US5648564A (en) 1995-12-21 1997-07-15 Kemin Industries, Inc. Process for the formation, isolation and purification of comestible xanthophyll crystals from plants
DE19609477A1 (de) 1996-03-11 1997-09-18 Basf Ag Stabile wäßrige Solubilisate von Carotinoiden und Vitamine
US5895652A (en) 1996-07-29 1999-04-20 Longevity Institute International Method of metabolic adjuvanation and cellular repair
CN1082507C (zh) 1996-10-04 2002-04-10 霍夫曼-拉罗奇有限公司 叶黄素的转化方法
DE19649062A1 (de) 1996-11-27 1998-05-28 Basf Ag Flüssige, mit Öl mischbare Carotinoid-Zubereitungen
US5804168A (en) 1997-01-29 1998-09-08 Murad; Howard Pharmaceutical compositions and methods for protecting and treating sun damaged skin
US5876782A (en) 1997-05-14 1999-03-02 Kemin Industries, Inc. Method for the conversion of xanthophylls in plant material
WO2014073127A1 (ja) 2012-11-09 2014-05-15 パナソニック株式会社 半導体装置及びその製造方法

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517197A (ja) * 2002-07-29 2006-07-20 ハワイ バイオテック， インコーポレイテッド 病気の抑制と改善のための構造上のカロチノイド類似体
JP2010248243A (ja) * 2002-07-29 2010-11-04 Cardax Pharmaceuticals Inc 病気の抑制と改善のための構造上のカロチノイド類似体
JP2009513641A (ja) * 2005-10-26 2009-04-02 アボット・ラボラトリーズ ドコサヘキサエン酸およびルテインを含有する乳児用製剤
JP2012131802A (ja) * 2005-10-26 2012-07-12 Abbott Lab ドコサヘキサエン酸およびルテインを含有する乳児用製剤
US8263147B2 (en) 2005-10-26 2012-09-11 Abbott Laboratories Infant formulas containing docosahexaenoic acid and lutein
US10342244B2 (en) 2005-10-26 2019-07-09 Abbott Laboratories Infant formulas containing docosahexaenoic acid and lutein
WO2008099469A1 (ja) * 2007-02-14 2008-08-21 Tohoku University 赤血球の脂質過酸化を抑制するための組成物および方法
JPWO2008099469A1 (ja) * 2007-02-14 2010-05-27 株式会社プロジェクト・エム 赤血球の脂質過酸化を抑制するための組成物および方法

Also Published As

Publication number Publication date
WO1998045241A3 (en) 1998-12-23
EP0984915A4 (en) 2002-11-27
AU7099098A (en) 1998-10-30
EP0984915A2 (en) 2000-03-15
AU752468B2 (en) 2002-09-19
US6313169B1 (en) 2001-11-06
WO1998045241A2 (en) 1998-10-15

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