AU752468B2 - Lutein esters having high bioavailability - Google Patents
Lutein esters having high bioavailability Download PDFInfo
- Publication number
- AU752468B2 AU752468B2 AU70990/98A AU7099098A AU752468B2 AU 752468 B2 AU752468 B2 AU 752468B2 AU 70990/98 A AU70990/98 A AU 70990/98A AU 7099098 A AU7099098 A AU 7099098A AU 752468 B2 AU752468 B2 AU 752468B2
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- Prior art keywords
- lutein
- weight
- composition
- consists essentially
- composition consists
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- 239000000203 mixture Substances 0.000 claims description 57
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- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4269797P | 1997-04-04 | 1997-04-04 | |
| US60/042697 | 1997-04-04 | ||
| US5434698A | 1998-04-02 | 1998-04-02 | |
| US09/054346 | 1998-04-02 | ||
| PCT/US1998/006278 WO1998045241A2 (en) | 1997-04-04 | 1998-04-03 | Lutein esters having high bioavailability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7099098A AU7099098A (en) | 1998-10-30 |
| AU752468B2 true AU752468B2 (en) | 2002-09-19 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU70990/98A Ceased AU752468B2 (en) | 1997-04-04 | 1998-04-03 | Lutein esters having high bioavailability |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6313169B1 (https=) |
| EP (1) | EP0984915A4 (https=) |
| JP (1) | JP2002513411A (https=) |
| AU (1) | AU752468B2 (https=) |
| WO (1) | WO1998045241A2 (https=) |
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| US6191293B1 (en) | 1998-04-20 | 2001-02-20 | Inexa, Industria Extractora C.A. | Trans-xanthophyll ester concentrates of enhanced purity and methods of making same |
| NL1010351C2 (nl) * | 1998-10-19 | 2001-01-08 | Werklust & Beheer B V | Esters van caroteno´den voor gebruik in de preventie en behandeling van oogaandoeningen. |
| US7078040B2 (en) | 2000-03-27 | 2006-07-18 | Fuji Chemical Industry Co., Ltd. | Method of inhibiting the expression of inflammatory cytokines and chemokines |
| SE0001071D0 (sv) * | 2000-03-27 | 2000-03-27 | Astacarotene Ab | Method of inhibiting the expression of inflammatory cytokines and chemokines |
| BR0207405B1 (pt) * | 2001-02-23 | 2012-09-18 | novos ésteres carotenóides. | |
| US6784351B2 (en) * | 2001-06-29 | 2004-08-31 | Ball Horticultural Company | Targetes erecta marigolds with altered carotenoid compositions and ratios |
| US6811801B2 (en) | 2001-12-12 | 2004-11-02 | Abbott Laboratories | Methods and compositions for brightening the color of thermally processed nutritionals |
| JP2003201497A (ja) * | 2002-01-08 | 2003-07-18 | Riken Vitamin Co Ltd | ルテイン脂肪酸エステル濃縮物の製造方法 |
| US6737535B2 (en) | 2002-06-05 | 2004-05-18 | Kancor Flavours And Extracts Limited | Trans-lutein enriched xanthophyll ester concentrate and a process for its preparation |
| US7345091B2 (en) | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| EP2392562B1 (en) * | 2002-07-29 | 2018-03-07 | Cardax Pharma, Inc. | Structural carotenoid analogs for the inhibition and amelioration of disease |
| US7375133B2 (en) * | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
| US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
| US7763649B2 (en) | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
| US7723327B2 (en) | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
| US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
| US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
| US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
| US7320997B2 (en) | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
| US6743953B2 (en) | 2002-08-26 | 2004-06-01 | Kancor Flavours & Extracts Ltd. | Process for the preparation of xanthophyll crystals |
| WO2005025586A1 (en) | 2003-09-12 | 2005-03-24 | Access Business Group International Llc | Cytokine modulators and related method of use |
| PE20050398A1 (es) * | 2003-09-22 | 2005-06-03 | Rosales Jose Antonio Socla | Proceso y purificacion de las xantofilas de marigold |
| US7446101B1 (en) | 2003-12-12 | 2008-11-04 | Bioactives, Llc | Bioavailable carotenoid-cyclodextrin formulations for soft-gels and other encapsulation systems |
| EP1750723A1 (en) * | 2004-04-14 | 2007-02-14 | Hawaii Biotech, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| US20060018842A1 (en) * | 2004-06-25 | 2006-01-26 | Gary Blumenthal | Composition and method for delivery of phytochemicals |
| US7351424B2 (en) | 2004-07-22 | 2008-04-01 | Bio Lut S.A. De C.V. | Enhanced purity trans-lutein-ester compositions and methods of making same |
| US20060024247A1 (en) * | 2004-07-28 | 2006-02-02 | Bioactives, Llc | Oral care formulations comprising highly bioavailable Coenzyme Q-10 cyclodextrin complex |
| US20070065487A1 (en) * | 2005-09-21 | 2007-03-22 | Bio Lut S.A. De C.V. | Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof |
| US20070166354A1 (en) | 2005-10-26 | 2007-07-19 | Bridget Barrett-Reis | Method of reducing the risk of retinopathy of prematurity in preterm infants |
| US7829126B2 (en) * | 2005-10-26 | 2010-11-09 | Abbott Laboratories | Infant formulas containing docosahexaenoic acid and lutein |
| AT503329A1 (de) | 2006-03-02 | 2007-09-15 | Omnica Gmbh | Verfahren zur herstellung einer zusammensetzung, welche zumindest ein xantophyll enthält |
| WO2008023283A2 (en) * | 2006-08-25 | 2008-02-28 | Omnica Gmbh | Stabilized esters of lutein |
| EP2123263A1 (en) * | 2007-02-14 | 2009-11-25 | Tohoku University | Composition and method for suppressing lipid peroxidation in erythrocytes |
| DE102017009186A1 (de) | 2017-09-25 | 2019-03-28 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Lutein und -derivate enthaltende Zusammensetzung sowie Verfahren zur Herstellung |
| US11089954B2 (en) | 2018-09-21 | 2021-08-17 | MacuLogix, Inc. | Method and apparatus for guiding a test subject through an ophthalmic test |
| CN112402593A (zh) * | 2020-10-22 | 2021-02-26 | 宁波君瑞生物科技有限公司 | 一种缓解运动膝关节不适的凝胶制剂 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2527602A (en) | 1947-07-29 | 1950-10-31 | Monroe E Wall | Process of separating carotene fractions and tocopherol-sterol fractions from green plant materials |
| CH420822A (de) | 1960-10-17 | 1966-09-15 | Hoffmann La Roche | Wasserdispergierbare Carotinoidzubereitung |
| US3523138A (en) | 1965-03-01 | 1970-08-04 | Eastman Kodak Co | Treatment of marigold petal meal to obtain a xanthophyll product |
| US3558712A (en) | 1967-02-23 | 1971-01-26 | Hoffmann La Roche | Method for the synthesis of zeaxanthins,xanthophylis,and 3-oxo-beta carotene |
| US3661997A (en) | 1967-02-23 | 1972-05-09 | Hoffmann La Roche | Mono-oxo carotenes |
| US3989757A (en) | 1973-08-29 | 1976-11-02 | Hoffmann-La Roche Inc. | Isomerizing cis-carotenoids to all-trans-carotenoids |
| US3997679A (en) | 1974-08-12 | 1976-12-14 | Cpc International Inc. | Stabilization of xanthophylls |
| US4048203A (en) | 1976-12-06 | 1977-09-13 | Thomas Philip | Purification of lutein-fatty acid esters from plant materials |
| US4851339A (en) | 1986-04-01 | 1989-07-25 | Hills Christopher B | Extraction of anti-mutagenic pigments from algae and vegetables |
| IL88961A (en) | 1988-01-29 | 1992-07-15 | Basf Ag | Stable mixtures containing oxidation-sensitive compounds |
| US5019668A (en) | 1988-06-14 | 1991-05-28 | Palm Oil Research & Development Board | Recovery of carotenoids |
| US5180747A (en) | 1989-02-28 | 1993-01-19 | Nisshin Flour Milling Co., Ltd. | Stabilized fat-soluble vitamin compositions |
| US5290605A (en) | 1989-06-29 | 1994-03-01 | Niva Shapira | Sun-exposure nutritional supporting composition |
| US5157132A (en) | 1990-05-18 | 1992-10-20 | Carotech Associates | Integrated process for recovery of carotenoids and tocotrienols from oil |
| MC2309A1 (fr) | 1990-10-01 | 1993-09-27 | Brigham & Womens Hospital | Traitement a base de beta-carotene et de vitamines pour inhiber les accidents vasculaires majeurs |
| DE69232376T2 (de) | 1991-09-06 | 2002-09-26 | Cognis Australien Pty.Ltd., Victoria | Carotinoide zusammensetzung |
| GB9219524D0 (en) | 1992-09-15 | 1992-10-28 | Smithkline Beecham Plc | Novel composition |
| DE19609538A1 (de) | 1996-03-11 | 1997-09-18 | Basf Ag | Feinverteilte Carotinoid- und Retinoidsuspensionen und Verfahren zu ihrer Herstellung |
| EP0689427B1 (en) | 1993-03-22 | 2002-06-12 | Cognis Australia Pty Ltd | Water dispersible therapeutic carotenoid compounds |
| DE69424537T2 (de) | 1993-03-22 | 2001-11-15 | Cognis Australien Pty.Ltd., Victoria | Therapeutischer wirkstoff zur behandlung von melanomen |
| IL110139A0 (en) * | 1993-06-28 | 1994-10-07 | Howard Foundation | Pharmaceutically-active antioxidants |
| US5382714A (en) | 1994-03-17 | 1995-01-17 | The Catholic University Of America | Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof |
| AUPM493194A0 (en) | 1994-04-08 | 1994-05-05 | Buckmeier, Julie A. | Therapeutic agent for inhibiting the conversion of epithelial cells to tumours |
| US5523494A (en) | 1994-07-20 | 1996-06-04 | Industrial Organica, S.A. De C.V. | Process for the isomerization of lutein |
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| US5643623A (en) | 1995-06-07 | 1997-07-01 | Mars Incorporated | Health food product and its uses |
| US5602286A (en) | 1995-06-07 | 1997-02-11 | Cargill, Incorporated | Process for recovering xanthophylls from corn gluten |
| FR2735364B1 (fr) | 1995-06-16 | 1997-08-01 | Oreal | Composition cosmetique ou dermatologique a liberation controlee d'actif contenant un carotenoide photoconvertible |
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| DE19649062A1 (de) | 1996-11-27 | 1998-05-28 | Basf Ag | Flüssige, mit Öl mischbare Carotinoid-Zubereitungen |
| US5804168A (en) | 1997-01-29 | 1998-09-08 | Murad; Howard | Pharmaceutical compositions and methods for protecting and treating sun damaged skin |
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| WO2014073127A1 (ja) | 2012-11-09 | 2014-05-15 | パナソニック株式会社 | 半導体装置及びその製造方法 |
-
1998
- 1998-04-03 JP JP54285098A patent/JP2002513411A/ja not_active Ceased
- 1998-04-03 WO PCT/US1998/006278 patent/WO1998045241A2/en not_active Ceased
- 1998-04-03 AU AU70990/98A patent/AU752468B2/en not_active Ceased
- 1998-04-03 EP EP98917966A patent/EP0984915A4/en not_active Withdrawn
-
2000
- 2000-03-16 US US09/526,902 patent/US6313169B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998045241A3 (en) | 1998-12-23 |
| EP0984915A4 (en) | 2002-11-27 |
| AU7099098A (en) | 1998-10-30 |
| EP0984915A2 (en) | 2000-03-15 |
| US6313169B1 (en) | 2001-11-06 |
| WO1998045241A2 (en) | 1998-10-15 |
| JP2002513411A (ja) | 2002-05-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TC | Change of applicant's name (sec. 104) |
Owner name: COGNIS CORPORATION Free format text: FORMER NAME: HENKEL CORPORATION |
|
| TC | Change of applicant's name (sec. 104) |
Owner name: COGNIS CORPORATION, PHYLLIS E. BOWEN Free format text: FORMER NAME: COGNIS CORPORATION |
|
| TH | Corrigenda |
Free format text: IN VOL 16, NO 31, PAGE(S) 7403 UNDER THE HEADING CHANGE OF NAME(S) OF APPLICANT(S), SECTION 104 IN THE NAME OF HENKEL CORPORATION, PLEASE AMEND THE APPLICANTS TO READ COGNIS CORPORATION, PHYLLIS E. BOWEN |
|
| SREP | Specification republished | ||
| FGA | Letters patent sealed or granted (standard patent) |