ES2178651T3 - Compuestos carotenoides terapeuticos deispersables en agua. - Google Patents

Compuestos carotenoides terapeuticos deispersables en agua.

Info

Publication number
ES2178651T3
ES2178651T3 ES94911015T ES94911015T ES2178651T3 ES 2178651 T3 ES2178651 T3 ES 2178651T3 ES 94911015 T ES94911015 T ES 94911015T ES 94911015 T ES94911015 T ES 94911015T ES 2178651 T3 ES2178651 T3 ES 2178651T3
Authority
ES
Spain
Prior art keywords
pct
deispersable
therapeutic
water
carotenoid compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94911015T
Other languages
English (en)
Inventor
Lance Elliott Schlipalius
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cognis Australia Pty Ltd
Original Assignee
Cognis Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cognis Australia Pty Ltd filed Critical Cognis Australia Pty Ltd
Application granted granted Critical
Publication of ES2178651T3 publication Critical patent/ES2178651T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE PRESENTA UN AGENTE TERAPEUTICO PARA SU ADMINISTRACION MEDIANTE INYECCION O DE FORMA INTRAVENOSA QUE INCLUYE LA MECLA DE: A) UN COMPONENTE DISPERSIBLE O SOLUBLE EN AGUA; B) UN COMPONENTE EMULSIFICANTE; Y C) UN AGENTE TERAPEUTICO INSOLUBLE EN AGUA EN UN MEDIO PORTADOR ADECUADO.
ES94911015T 1993-03-22 1994-03-22 Compuestos carotenoides terapeuticos deispersables en agua. Expired - Lifetime ES2178651T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPL793593 1993-03-22

Publications (1)

Publication Number Publication Date
ES2178651T3 true ES2178651T3 (es) 2003-01-01

Family

ID=3776794

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94911015T Expired - Lifetime ES2178651T3 (es) 1993-03-22 1994-03-22 Compuestos carotenoides terapeuticos deispersables en agua.

Country Status (8)

Country Link
US (1) US5773026A (es)
EP (1) EP0689427B1 (es)
JP (1) JPH08510995A (es)
AT (1) ATE218855T1 (es)
AU (1) AU696956B2 (es)
DE (1) DE69430799T2 (es)
ES (1) ES2178651T3 (es)
WO (1) WO1994021232A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9106938A (pt) * 1990-10-01 1993-09-28 Brigham & Womens Hospital Terapia de beta-caroteno e vitamina e para inibicao de ocorrencias vasculares maiores
US6132790A (en) * 1991-09-06 2000-10-17 Betatene Limited Carotenoid composition
AUPM493194A0 (en) * 1994-04-08 1994-05-05 Buckmeier, Julie A. Therapeutic agent for inhibiting the conversion of epithelial cells to tumours
AU700249B2 (en) * 1994-04-08 1998-12-24 Cognis Australia Pty Ltd Carotenoid agent for inhibiting the conversion of epithelial cells to tumours
EP0760650B1 (en) * 1994-05-20 2002-07-31 Novavax, Inc. Antimicrobial oil-in-water emulsions
DE19609476A1 (de) * 1996-03-11 1997-09-18 Basf Ag Stabile zur parenteralen Verabreichung geeignete Carotinoid-Emulsionen
AU5806898A (en) * 1996-12-31 1998-07-31 Inhale Therapeutic Systems Processes and compositions for spray drying hydrophobic drugs in organic solventsuspensions of hydrophilic excipients
EP0984915A4 (en) 1997-04-04 2002-11-27 Henkel Corp LUTEINE ESTERS WITH HIGH BIOAVAILABILITY
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
ATE252889T1 (de) 1998-08-19 2003-11-15 Skyepharma Canada Inc Injizierbare wässerige propofoldispersionen
US6767342B1 (en) 2001-04-23 2004-07-27 Evelyna D. Cantwell Oxygen bandage system
US20050009788A1 (en) * 2002-07-29 2005-01-13 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling connexin 43 expression
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
JP4601549B2 (ja) * 2002-07-29 2010-12-22 カルダックス ファーマスーティカルズ インコーポレイテッド 病気の抑制と改善のための構造上のカロチノイド類似体
US7763649B2 (en) * 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US7723327B2 (en) * 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US8088363B2 (en) 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
CA2564066A1 (en) * 2004-04-14 2005-11-03 Hawaii Biotech, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US7351424B2 (en) * 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
US20070065487A1 (en) * 2005-09-21 2007-03-22 Bio Lut S.A. De C.V. Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof
GB0523431D0 (en) * 2005-11-17 2005-12-28 Inst For Akvakulturforskning A Method
EP2427050B1 (en) * 2009-05-07 2019-10-16 Huntsman Corporation Australia Pty Limited Dispersants in high-electrolyte solutions

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572915A (en) * 1984-05-01 1986-02-25 Bioglan Laboratories Clear micellized solutions of fat soluble essential nutrients
US4680314A (en) * 1985-08-30 1987-07-14 Microbio Resources, Inc. Process for producing a naturally-derived carotene/oil composition by direct extraction from algae
AU595824B2 (en) * 1985-08-30 1990-04-12 Betatene Limited Narurally-derived carotene/oil composition and the process for the production thereof by direct extraction of carotene from algae
EP0397774A1 (en) * 1988-02-04 1990-11-22 Board Of Regents, The University Of Texas System Formulation and use of retinoids in treatment of cancer and other diseases
JPH0225418A (ja) * 1988-07-14 1990-01-26 Kyorin Pharmaceut Co Ltd イブジラスト脂肪乳剤およびその製造方法
DE3903056A1 (de) * 1989-02-02 1990-08-09 Braun Melsungen Ag Fettemulsion zur intraperitonealen applikation, ihre herstellung und anwendung
GB8919172D0 (en) * 1989-08-23 1989-10-04 Univ Nottingham Useful composition
BR9106938A (pt) * 1990-10-01 1993-09-28 Brigham & Womens Hospital Terapia de beta-caroteno e vitamina e para inibicao de ocorrencias vasculares maiores
DE4031094A1 (de) * 1990-10-02 1992-04-09 Basf Ag Verfahren zur herstellung von stabilen injizierbaren (beta)-carotin-solubilisaten
PH31204A (en) * 1990-11-02 1998-05-05 Fujisawa Pharmaceutical Co Pharmaceutical composition.
US5298246A (en) * 1991-01-09 1994-03-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Stable pharmaceutical composition and method for its production
CH681152A5 (de) * 1991-06-04 1993-01-29 Marigen S.A. Neue biotenside und antitumorale ester und phosphatide mit vitamin-d- und vitamin-e-verbindungen, ihre herstellung und aufarbeitung zu spontan dispergierbaren konzentraten.
JP3302999B2 (ja) * 1991-09-06 2002-07-15 コグニス・オーストラリア・プロプライエタリ・リミテッド カロチノイド・コンポジション
AU3442093A (en) * 1992-01-16 1993-08-03 Argus Pharmaceuticals, Inc. Formulation and use of carotenoids in treatment of cancer
DE69327100T2 (de) * 1992-06-04 2000-04-13 Betatene Pty. Ltd., Cheltenham Gemisch mit hohem gehalt an cis beta-carotin

Also Published As

Publication number Publication date
WO1994021232A1 (en) 1994-09-29
AU6370594A (en) 1994-10-11
JPH08510995A (ja) 1996-11-19
EP0689427A1 (en) 1996-01-03
DE69430799D1 (de) 2002-07-18
ATE218855T1 (de) 2002-06-15
AU696956B2 (en) 1998-09-24
DE69430799T2 (de) 2003-02-13
US5773026A (en) 1998-06-30
EP0689427B1 (en) 2002-06-12
EP0689427A4 (en) 1998-04-15

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