JP2002505679A - 乳房投射撮影用静脈内造影剤の使用および装置 - Google Patents
乳房投射撮影用静脈内造影剤の使用および装置Info
- Publication number
- JP2002505679A JP2002505679A JP50374199A JP50374199A JP2002505679A JP 2002505679 A JP2002505679 A JP 2002505679A JP 50374199 A JP50374199 A JP 50374199A JP 50374199 A JP50374199 A JP 50374199A JP 2002505679 A JP2002505679 A JP 2002505679A
- Authority
- JP
- Japan
- Prior art keywords
- contrast agent
- intravenous
- mammography
- contrast
- iodine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002872 contrast media Substances 0.000 title claims abstract description 75
- 238000009607 mammography Methods 0.000 title claims abstract description 33
- 238000001990 intravenous administration Methods 0.000 title claims abstract description 29
- 239000000032 diagnostic agent Substances 0.000 claims abstract description 3
- 229940039227 diagnostic agent Drugs 0.000 claims abstract description 3
- 238000004519 manufacturing process Methods 0.000 claims abstract description 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 24
- 229910052740 iodine Inorganic materials 0.000 claims description 24
- 239000011630 iodine Substances 0.000 claims description 24
- 230000037396 body weight Effects 0.000 claims description 13
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 12
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 12
- 229910052794 bromium Inorganic materials 0.000 claims description 12
- 150000001875 compounds Chemical class 0.000 claims description 11
- 239000013522 chelant Substances 0.000 claims description 3
- 239000012615 aggregate Substances 0.000 claims description 2
- 238000010276 construction Methods 0.000 claims description 2
- 239000002502 liposome Substances 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 239000011859 microparticle Substances 0.000 claims description 2
- 239000002105 nanoparticle Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 208000025865 Ulcer Diseases 0.000 claims 1
- 230000036269 ulceration Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 19
- 230000003902 lesion Effects 0.000 abstract description 9
- 230000035945 sensitivity Effects 0.000 abstract description 8
- 238000003325 tomography Methods 0.000 abstract description 4
- 230000000153 supplemental effect Effects 0.000 abstract description 2
- 238000012795 verification Methods 0.000 abstract description 2
- 238000003384 imaging method Methods 0.000 description 17
- 230000005855 radiation Effects 0.000 description 13
- 210000000481 breast Anatomy 0.000 description 12
- 229920001817 Agar Polymers 0.000 description 8
- 208000026310 Breast neoplasm Diseases 0.000 description 7
- 239000008272 agar Substances 0.000 description 7
- 238000002347 injection Methods 0.000 description 7
- 239000007924 injection Substances 0.000 description 7
- 206010028980 Neoplasm Diseases 0.000 description 6
- 238000001514 detection method Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 210000000038 chest Anatomy 0.000 description 4
- 238000010253 intravenous injection Methods 0.000 description 4
- 238000002601 radiography Methods 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 238000002583 angiography Methods 0.000 description 3
- 229910052797 bismuth Inorganic materials 0.000 description 3
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 3
- DGAIEPBNLOQYER-UHFFFAOYSA-N iopromide Chemical compound COCC(=O)NC1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)N(C)CC(O)CO)=C1I DGAIEPBNLOQYER-UHFFFAOYSA-N 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 206010006187 Breast cancer Diseases 0.000 description 2
- XUHXFSYUBXNTHU-UHFFFAOYSA-N Iotrolan Chemical compound IC=1C(C(=O)NC(CO)C(O)CO)=C(I)C(C(=O)NC(CO)C(O)CO)=C(I)C=1N(C)C(=O)CC(=O)N(C)C1=C(I)C(C(=O)NC(CO)C(O)CO)=C(I)C(C(=O)NC(CO)C(O)CO)=C1I XUHXFSYUBXNTHU-UHFFFAOYSA-N 0.000 description 2
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 229940039231 contrast media Drugs 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000004807 localization Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000002485 urinary effect Effects 0.000 description 2
- 238000007487 urography Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- VPMMJSPGZSFEAH-UHFFFAOYSA-N 2,4-diaminophenol;hydrochloride Chemical compound [Cl-].NC1=CC=C(O)C([NH3+])=C1 VPMMJSPGZSFEAH-UHFFFAOYSA-N 0.000 description 1
- VEQHDYOJOHHDAK-UHFFFAOYSA-N 2-[2-[2-(ethylamino)ethylamino]ethylamino]acetic acid Chemical compound CCNCCNCCNCC(O)=O VEQHDYOJOHHDAK-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 208000004434 Calcinosis Diseases 0.000 description 1
- 241000238366 Cephalopoda Species 0.000 description 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- 241000766026 Coregonus nasus Species 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- 241001490312 Lithops pseudotruncatella Species 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 238000002083 X-ray spectrum Methods 0.000 description 1
- 238000000862 absorption spectrum Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000008139 complexing agent Substances 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- IZOOGPBRAOKZFK-UHFFFAOYSA-K gadopentetate Chemical compound [Gd+3].OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O IZOOGPBRAOKZFK-UHFFFAOYSA-K 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229960003182 iotrolan Drugs 0.000 description 1
- UUMLTINZBQPNGF-UHFFFAOYSA-N ioxilan Chemical compound OCC(O)CN(C(=O)C)C1=C(I)C(C(=O)NCCO)=C(I)C(C(=O)NCC(O)CO)=C1I UUMLTINZBQPNGF-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229960003194 meglumine Drugs 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000001613 neoplastic effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000011410 subtraction method Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000002303 tibia Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0457—Semi-solid forms, ointments, gels, hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.乳房投射撮影用診断剤製造のための静脈内造影剤の使用。 2.静脈内造影剤が造影元素としてヨードを含有することを特徴とする請求項1 記載の造影剤の使用。 3.静脈内造影剤が造影元素として臭素を含有することを特徴とする請求項1記 載の造影剤の使用。 4.静脈内造影剤が、原子番号34、42、44〜52、54〜60、62〜7 9、82または83の元素の化合物を含有することを特徴とする請求項1記載の 造影剤の使用。 5.静脈内造影剤が、原子番号56〜60、62〜79、82または83の元素 の金属キレートを含有することを特徴とする請求項1記載の造影剤の使用。 6.静脈内造影剤が10000〜80000Dの分子量を有することを特徴とす る請求項1記載の造影剤の使用。 7.静脈内造影剤が高分子構造で存在することを特徴とする請求項1記載の造影 剤の使用。 8.静脈内造影剤が会合体、リポソーム、ナノ粒子またはミクロ粒子の形で存在 することを特徴とする請求項7記載の造影剤の使用。 9.ヨード100mg/ml〜ヨード500mg/mlに相当するX線潰度で存 在することを特徴とする 請求項1記載の静脈内造影剤の使用。 10.ヨード100mg/ml〜ヨード500mg/mlの濃度で存在すること を特徴とする請求項2記載の静脈内造影剤の使用。 11.体重1kg当たりヨード150mgから体重1kg当たりヨード1500 mgに相当する用量で投与されることを特徴とする請求項2記載の静脈内造影剤 の使用。 12.臭素100mg/ml〜500mg/mlno濃度で存在することを特徴 とする請求項3記載の静脈内造影剤の使用。 13.体重1kg当たり臭素100mgから体重1kg当たり1500mgに相 当する用量で投与されることを特徴とする請求項3記載の静脈内造影剤の使用。 14.10mモル〜2モル/lの濃度で存在することを特徴とする静脈内造影剤 の使用。 15.体重1kg当たり0.1〜2mモルの用量で適用されることを特徴とする 請求項4記載の静脈内造影剤の使用。 16.10mモル/1〜2モル/lの濃度で存在することを特徴とする請求項5 記載の静脈内造影剤の使用。 17.体重1kg当たり0.1〜2mモルの用量で適用されることを特徴とする 請求項5記載の静脈内造 影剤の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97250190.2 | 1997-06-20 | ||
EP97250190A EP0885616A1 (de) | 1997-06-20 | 1997-06-20 | Verwendung von intravenösen Kontrastmitteln sowie Vorrichtungen für die Projektionsmammographie |
PCT/EP1998/003658 WO1998058679A1 (de) | 1997-06-20 | 1998-06-19 | Verwendung von intravenösen kontrastmitteln für die projektionsmammographie |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010223769A Division JP2011012074A (ja) | 1997-06-20 | 2010-10-01 | 乳房投射撮影用静脈内造影剤の使用および装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2002505679A true JP2002505679A (ja) | 2002-02-19 |
JP4664449B2 JP4664449B2 (ja) | 2011-04-06 |
Family
ID=8229158
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50374199A Expired - Fee Related JP4664449B2 (ja) | 1997-06-20 | 1998-06-19 | 乳房投射撮影用静脈内造影剤の使用および装置 |
JP50374299A Pending JP2002504843A (ja) | 1997-06-20 | 1998-06-19 | 乳房投射撮影装置 |
JP2010223769A Pending JP2011012074A (ja) | 1997-06-20 | 2010-10-01 | 乳房投射撮影用静脈内造影剤の使用および装置 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50374299A Pending JP2002504843A (ja) | 1997-06-20 | 1998-06-19 | 乳房投射撮影装置 |
JP2010223769A Pending JP2011012074A (ja) | 1997-06-20 | 2010-10-01 | 乳房投射撮影用静脈内造影剤の使用および装置 |
Country Status (28)
Country | Link |
---|---|
US (2) | US20020031475A1 (ja) |
EP (3) | EP0885616A1 (ja) |
JP (3) | JP4664449B2 (ja) |
KR (2) | KR20010013980A (ja) |
CN (2) | CN1263449A (ja) |
AT (1) | ATE229820T1 (ja) |
AU (2) | AU747033B2 (ja) |
BG (2) | BG64895B1 (ja) |
BR (2) | BR9810205A (ja) |
CA (2) | CA2294187A1 (ja) |
CZ (1) | CZ298462B6 (ja) |
DE (1) | DE59806743D1 (ja) |
DK (1) | DK0994729T3 (ja) |
HK (1) | HK1029759A1 (ja) |
HU (2) | HU225522B1 (ja) |
IL (2) | IL133574A (ja) |
NO (2) | NO315638B1 (ja) |
NZ (2) | NZ501603A (ja) |
PL (2) | PL337286A1 (ja) |
RS (1) | RS49734B (ja) |
RU (1) | RU2194533C2 (ja) |
SI (2) | SI20152A (ja) |
SK (2) | SK181199A3 (ja) |
TR (2) | TR199903144T2 (ja) |
UA (1) | UA71895C2 (ja) |
WO (2) | WO1998058679A1 (ja) |
YU (1) | YU66299A (ja) |
ZA (1) | ZA985395B (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10118792B4 (de) * | 2001-04-05 | 2005-12-22 | Schering Ag | Anordnung zur Aufnahme von Projektionsmammogrammen und Verwendung der Anordnung für die Projektionsmammographie |
FR2823969B1 (fr) * | 2001-04-30 | 2003-12-26 | Ge Med Sys Global Tech Co Llc | Procede de prelevement d'un tissu au cours d'un examen par rayons x et dispositif de mise en oeuvre |
DE102005033235A1 (de) * | 2005-07-15 | 2007-01-18 | Siemens Ag | Verfahren zur Visualisierung eines vaskulären Einsatzstücks |
US20080167552A1 (en) * | 2007-01-04 | 2008-07-10 | General Electric Company | System and method of generating an image of a contrast agent injected into an imaged subject |
FR2927719B1 (fr) | 2008-02-19 | 2010-03-26 | Gen Electric | Procede de traitement d'images obtenues par tomosynthese et dispositif associe |
US8315449B2 (en) * | 2008-06-24 | 2012-11-20 | Medrad, Inc. | Identification of regions of interest and extraction of time value curves in imaging procedures |
JP2012055549A (ja) * | 2010-09-10 | 2012-03-22 | Fujifilm Corp | バイオプシ用ファントム |
FR2967888B1 (fr) * | 2010-11-26 | 2012-12-21 | Gen Electric | Procede de galactographie et mammographe pour l'execution dudit procede |
US9651138B2 (en) | 2011-09-30 | 2017-05-16 | Mtd Products Inc. | Speed control assembly for a self-propelled walk-behind lawn mower |
DE102012217301B4 (de) | 2012-09-25 | 2021-10-14 | Bayer Pharma Aktiengesellschaft | Kombination aus Kontrastmittel und Mammographie-CT-System mit vorgegebenem Energiebereich und Verfahren zur Erzeugung tomographischer Mammographie-CT-Aufnahmen durch diese Kombination |
EA036245B1 (ru) * | 2017-10-26 | 2020-10-16 | Казахский научно-исследовательский институт онкологии и радиологии | Способ диагностики рака молочной железы |
EP3498306A1 (de) * | 2017-12-16 | 2019-06-19 | Bionorica SE | Extrakte aus vitex agnus castus zur behandlung und diagnose von brustkrebs |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5756066A (en) * | 1995-06-07 | 1998-05-26 | Schering Aktiengesellschaft | Iodine-containing peptides |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4192859A (en) * | 1978-09-29 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Contrast media containing liposomes as carriers |
FR2541272A1 (fr) * | 1983-02-23 | 1984-08-24 | Guerbet Sa | Composes bromes et produits opacifiants en contenant |
WO1987002893A1 (en) * | 1985-11-18 | 1987-05-21 | Board Of Regents, The University Of Texas System | Polychelating agents for image and spectral enhancement (and spectral shift) |
US5260050A (en) * | 1988-09-29 | 1993-11-09 | Ranney David F | Methods and compositions for magnetic resonance imaging comprising superparamagnetic ferromagnetically coupled chromium complexes |
GB8906130D0 (en) * | 1989-03-17 | 1989-05-04 | Nycomed As | Compositions |
DE3938992A1 (de) * | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
US5844965A (en) * | 1989-11-24 | 1998-12-01 | Thomas Jefferson University | Method and apparatus for using film density measurements of a radiograph to monitor the reproducibility of X-ray exposure parameters of a mammography unit |
DE4232925A1 (de) * | 1992-09-28 | 1994-03-31 | Diagnostikforschung Inst | 3-,8-substituierte Deuteroporphyrinderivate, diese enthaltende pharmazeutische Mittel und Verfahren zu ihrer Herstellung |
US5411730A (en) * | 1993-07-20 | 1995-05-02 | Research Corporation Technologies, Inc. | Magnetic microparticles |
DE4417628C1 (de) * | 1994-05-19 | 1995-09-28 | Siemens Ag | Verfahren zur adaptiven Rauschverminderung für digitale Bildsequenzen |
AU4173896A (en) * | 1994-11-30 | 1996-06-19 | Schering Aktiengesellschaft | Use of chelate compounds as diagnostic agents in the x-ray examination of liver and bile ducts |
US5804164A (en) * | 1996-03-13 | 1998-09-08 | Research Corporation Technologies, Inc. | Water-soluble lipophilic contrast agents |
US6009342A (en) * | 1997-02-28 | 1999-12-28 | The Regents Of The University Of California | Imaging method for the grading of tumors |
-
1997
- 1997-06-20 EP EP97250190A patent/EP0885616A1/de not_active Withdrawn
-
1998
- 1998-06-19 KR KR19997012006A patent/KR20010013980A/ko not_active Application Discontinuation
- 1998-06-19 SK SK1811-99A patent/SK181199A3/sk unknown
- 1998-06-19 RS YUP-661/99A patent/RS49734B/sr unknown
- 1998-06-19 PL PL98337286A patent/PL337286A1/xx unknown
- 1998-06-19 YU YU66299A patent/YU66299A/sh unknown
- 1998-06-19 CN CN98807066A patent/CN1263449A/zh active Pending
- 1998-06-19 US US09/446,328 patent/US20020031475A1/en not_active Abandoned
- 1998-06-19 CA CA002294187A patent/CA2294187A1/en not_active Abandoned
- 1998-06-19 NZ NZ501603A patent/NZ501603A/en unknown
- 1998-06-19 TR TR1999/03144T patent/TR199903144T2/xx unknown
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US5756066A (en) * | 1995-06-07 | 1998-05-26 | Schering Aktiengesellschaft | Iodine-containing peptides |
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