JP2001527068A5 - - Google Patents

Download PDF

Info

Publication number
JP2001527068A5
JP2001527068A5 JP2000526490A JP2000526490A JP2001527068A5 JP 2001527068 A5 JP2001527068 A5 JP 2001527068A5 JP 2000526490 A JP2000526490 A JP 2000526490A JP 2000526490 A JP2000526490 A JP 2000526490A JP 2001527068 A5 JP2001527068 A5 JP 2001527068A5
Authority
JP
Japan
Prior art keywords
alkyl
group
butyl
phenyl
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000526490A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001527068A (ja
JP4754068B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/027350 external-priority patent/WO1999033806A1/en
Publication of JP2001527068A publication Critical patent/JP2001527068A/ja
Publication of JP2001527068A5 publication Critical patent/JP2001527068A5/ja
Application granted granted Critical
Publication of JP4754068B2 publication Critical patent/JP4754068B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2000526490A 1997-12-24 1998-12-23 δ−オピオイドレセプターに結合する４−［アリール（ピペリジン−４−イル）］アミノベンズアミド類 Expired - Lifetime JP4754068B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6879497P 1997-12-24 1997-12-24
US60/068,794 1997-12-24
PCT/US1998/027350 WO1999033806A1 (en) 1997-12-24 1998-12-23 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor

Publications (3)

Publication Number Publication Date
JP2001527068A JP2001527068A (ja) 2001-12-25
JP2001527068A5 true JP2001527068A5 (enExample) 2006-01-12
JP4754068B2 JP4754068B2 (ja) 2011-08-24

Family

ID=22084747

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000526490A Expired - Lifetime JP4754068B2 (ja) 1997-12-24 1998-12-23 δ−オピオイドレセプターに結合する４−［アリール（ピペリジン−４−イル）］アミノベンズアミド類

Country Status (11)

Country Link
EP (1) EP1049676B1 (enExample)
JP (1) JP4754068B2 (enExample)
AT (1) ATE306472T1 (enExample)
AU (1) AU2009799A (enExample)
CA (1) CA2316341A1 (enExample)
DE (1) DE69831876T2 (enExample)
DK (1) DK1049676T3 (enExample)
ES (1) ES2251121T3 (enExample)
TW (1) TW476755B (enExample)
WO (1) WO1999033806A1 (enExample)
ZA (1) ZA9811842B (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
TW548271B (en) 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
CA2683097A1 (en) * 1998-03-10 1999-09-16 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
WO2000071518A2 (en) * 1999-05-25 2000-11-30 Sepracor, Inc. Heterocyclic analgesic compounds and their use
US7361666B2 (en) 1999-05-25 2008-04-22 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
US6635661B2 (en) 2000-05-25 2003-10-21 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
US6306876B1 (en) 1999-12-22 2001-10-23 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(8-azabicyclo[3.2.1]octan-3-yl)]aminobenzoic acid derivatives
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001208D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
WO2001092226A1 (en) 2000-05-25 2001-12-06 Sepracor, Inc. Heterocyclic analgesic compounds and method of use thereof
WO2002048122A2 (en) * 2000-12-14 2002-06-20 Ortho-Mcneil Pharmaceutical, Inc. Benzamidine derivatives
NZ525982A (en) 2000-12-15 2005-09-30 Astrazeneca Ab New process for the preparation of diaryl-4-amino-piperidinyl compounds
US6699890B2 (en) * 2000-12-22 2004-03-02 Memory Pharmaceuticals Corp. Phosphodiesterase 4 inhibitors
US7153871B2 (en) 2001-01-22 2006-12-26 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs
US7205320B2 (en) 2001-01-22 2007-04-17 Memory Pharmaceuticals Corp. Phosphodiesterase 4 inhibitors
MXPA03007261A (es) * 2001-02-14 2006-03-09 Abbott Lab Moduladores del receptor de glucocorticoides.
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
EP1395567B1 (en) 2001-05-18 2009-01-14 AstraZeneca AB 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
SE0101765D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101768D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101766D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0103313D0 (sv) 2001-10-03 2001-10-03 Astrazeneca Ab Novel compounds
HRP20050083A2 (en) 2002-07-19 2005-08-31 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs
ES2323688T3 (es) 2002-07-19 2009-07-23 Memory Pharmaceuticals Corporation Compuestos de 4-aminobenzofurano como inhibidores de fosfodiesterasa 4.
WO2004035541A1 (en) * 2002-10-15 2004-04-29 Janssen Pharmaceutica, N.V. Benzyl substituted (piperidin-4-yl) aminobenzamido derivatives as delta-opiod receptor modulators
ATE387443T1 (de) * 2002-10-15 2008-03-15 Janssen Pharmaceutica Nv Substituierte aminochinuclidin verbindungen und deren verwendung als delta-opioid rezeptor liganden
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
EP1569908B1 (en) 2002-11-19 2010-09-15 Memory Pharmaceuticals Corporation Pyridine n-oxide compounds as phosphodiesterase 4 inhibitors
ATE377589T1 (de) 2003-03-07 2007-11-15 Lilly Co Eli 6-substituierte nikotinamidderivate als opioidrezeptorantagonisten
JP4810423B2 (ja) 2003-06-27 2011-11-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 三環式デルタオピオイド調節剤
CA2549009A1 (en) * 2003-12-12 2005-07-07 Eli Lilly And Company Opioid receptor antagonists
CA2557794A1 (en) * 2004-03-15 2005-10-06 Eli Lilly And Company Opioid receptor antagonists
HRP20120343T1 (hr) 2004-08-02 2012-05-31 Astrazeneca Ab Derivati diarilmetil piperazina, njihovi pripravci i njihova uporaba
WO2007030089A1 (en) 2004-08-05 2007-03-15 Janssen Pharmaceutica N.V. Tricyclic delta- opioid modulators
SE0402485D0 (sv) 2004-10-13 2004-10-13 Astrazeneca Ab Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt
BRPI0518563A2 (pt) 2004-12-22 2008-11-25 Janssen Pharmaceutica Nv moduladores de delta-opiàide tricÍclicos
WO2006069277A1 (en) 2004-12-22 2006-06-29 Janssen Pharmaceutica N.V. TRICYCLIC δ-OPIOID MODULATORS
JP2008526878A (ja) * 2005-01-06 2008-07-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 三環式δ−オピオイド調節剤
CN101243079A (zh) 2005-06-16 2008-08-13 詹森药业有限公司 三环阿片调节剂
JP2007099761A (ja) * 2005-09-08 2007-04-19 Mitsui Chemicals Inc アミド誘導体ならびにその殺虫剤としての使用方法
MY148880A (en) 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
WO2011053706A1 (en) * 2009-10-30 2011-05-05 Janssen Pharmaceutica Nv 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators
CN113979997A (zh) * 2021-11-12 2022-01-28 中国科学院昆明植物研究所 N,n-(4-哌啶基、芳基)-3-氨基苯酚类衍生物及其药物组合物和其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019583A (en) * 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
IT1275433B (it) * 1995-05-19 1997-08-07 Smithkline Beecham Farma Derivati di diarildiammine
IT1277597B1 (it) * 1995-09-15 1997-11-11 Smithkline Beecham Spa Derivati di diarilalchenilammina
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds

Similar Documents

Publication Publication Date Title
JP2001527068A5 (enExample)
JP2018517746A5 (enExample)
RU2309953C2 (ru) Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
JP2012505836A5 (enExample)
JP2004525179A5 (enExample)
CN114026067A (zh) 用于治疗冠状病毒和小核糖核酸病毒感染的肽模拟物
RU97106776A (ru) Новые ингибиторы простагландинсинтазы
JP2003511384A5 (enExample)
JP2005534623A5 (enExample)
JP2003516404A5 (enExample)
JP2009542702A5 (enExample)
JP2005519908A5 (enExample)
JP2011525898A5 (enExample)
UY28496A1 (es) Compuestos de bencimidazolona que tienen actividad agonista del receptor 5-ht4
BR0015908A (pt) Emprego de compostos org nicos no tratamento de doenças
JP2015522547A5 (enExample)
CN101784532A (zh) 新的hiv逆转录酶抑制剂
JP2005511698A5 (enExample)
JP2024028337A5 (enExample)
JP2008505857A5 (enExample)
JP2019520344A5 (enExample)
JP2009514802A5 (enExample)
JP2020505354A5 (enExample)
CN114401962A (zh) 作为crbn蛋白调节剂的双并环类化合物
JP2002527414A5 (enExample)