JO2523B1 - طريقة محسنة لتحضير مستخلصات جنغو ذي محتوى قليل من 4-او ميثيل بايردكسين و/أو بفلافونات - Google Patents

طريقة محسنة لتحضير مستخلصات جنغو ذي محتوى قليل من 4-او ميثيل بايردكسين و/أو بفلافونات

Info

Publication number
JO2523B1
JO2523B1 JO200689A JOP20060089A JO2523B1 JO 2523 B1 JO2523 B1 JO 2523B1 JO 200689 A JO200689 A JO 200689A JO P20060089 A JOP20060089 A JO P20060089A JO 2523 B1 JO2523 B1 JO 2523B1
Authority
JO
Jordan
Prior art keywords
biflavones
improved method
low content
methyl pyridoxine
ginkgo extracts
Prior art date
Application number
JO200689A
Other languages
English (en)
Inventor
ارديلمير كليمينس
هاير هيرمن
كوتش ايجون
لانج فريدريش
Original Assignee
بوبلنتا ارزنيميتل جي ام بي اتش
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by بوبلنتا ارزنيميتل جي ام بي اتش filed Critical بوبلنتا ارزنيميتل جي ام بي اتش
Application granted granted Critical
Publication of JO2523B1 publication Critical patent/JO2523B1/ar

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

يتعلق الاختراع الحالي بطريقة مطورة متعددة الخطوات لتحضير خلاصة من الجنكه ثنائية الفص ذات المحتوى المنخفض من مركب 4- O- ميثيل بريودوكسين و/ او مركبات الفلافون الثنائية، حيث يتم اجراء الاستنفاد عن طريق الترشيح فوق راتنج مادة الامتزاز و / او مبادل ايوني ويتم احتجاز المواد المراد ازالتها على الراتنج، علاوة على ذلك يتعلق الاختراع بخلاصة من الجنكه ثنائية الفص ذات المحتوى المنخفض 4"-O ميثيل بريودوكسين و / او مركبات الفلافون الثنائية، والتي يمكن الحصول عليها باستخدام طريقة الاختراع الحالي كما يتعلق ايضا باستخدامها.
JO200689A 2005-05-03 2006-04-02 طريقة محسنة لتحضير مستخلصات جنغو ذي محتوى قليل من 4-او ميثيل بايردكسين و/أو بفلافونات JO2523B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005020685 2005-05-03
DE102005061948A DE102005061948A1 (de) 2005-05-03 2005-12-23 Verbessertes Verfahren zur Herstellung von 4'-O-Methylpyridoxin- und/oder Biflavon-armen Ginkgoextrakten

Publications (1)

Publication Number Publication Date
JO2523B1 true JO2523B1 (ar) 2010-03-17

Family

ID=36693938

Family Applications (1)

Application Number Title Priority Date Filing Date
JO200689A JO2523B1 (ar) 2005-05-03 2006-04-02 طريقة محسنة لتحضير مستخلصات جنغو ذي محتوى قليل من 4-او ميثيل بايردكسين و/أو بفلافونات

Country Status (26)

Country Link
US (2) US20060251746A1 (ar)
EP (1) EP1868625B1 (ar)
JP (2) JP4304230B2 (ar)
KR (1) KR100933721B1 (ar)
CN (2) CN101175505A (ar)
AR (1) AR054270A1 (ar)
AT (1) ATE401903T1 (ar)
AU (1) AU2006243378B2 (ar)
BR (1) BRPI0611093B1 (ar)
CA (1) CA2606843C (ar)
DE (2) DE102005061948A1 (ar)
DK (1) DK1868625T3 (ar)
DO (1) DOP2006000091A (ar)
ES (1) ES2310408T3 (ar)
JO (1) JO2523B1 (ar)
MX (1) MX2007013398A (ar)
MY (1) MY143650A (ar)
NZ (1) NZ563818A (ar)
PE (1) PE20061296A1 (ar)
PL (1) PL1868625T3 (ar)
PT (1) PT1868625E (ar)
RU (1) RU2367459C2 (ar)
SI (1) SI1868625T1 (ar)
TW (1) TWI376230B (ar)
UA (1) UA84519C2 (ar)
WO (1) WO2006117169A1 (ar)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE041715T2 (hu) 2007-12-21 2019-05-28 Dr Willmar Schwabe Gmbh & Co Kg Ginkgo biloba levél-kivonat alkalmazása
EP2494979B1 (de) 2011-03-04 2019-03-27 Dr. Willmar Schwabe GmbH & Co. KG Verwendung von Extrakten aus Blättern von Ginkgo biloba zur Prävention und Therapie von Komplikationen nach operativer Arteriosklerose-Behandlung sowie von Folgeerscheinungen der Arteriosklerose
MX341428B (es) 2011-04-27 2016-08-18 Dr Willmar Schwabe Gmbh & Co Kg Tableta de liberacion controlada de extracto de ginkgo biloba y procedimiento para su obtencion.
DE102014202318B4 (de) * 2014-02-10 2016-10-06 Dr. Willmar Schwabe Gmbh & Co. Kg Verbessertes Verfahren zur Herstellung von Ginkgoextrakten
CN103919768B (zh) * 2014-03-30 2016-03-16 吴静 一种含有异银杏双黄酮和白果内酯的药物组合物及其制剂
CN107509997B (zh) * 2017-09-08 2021-02-26 南京林业大学 一种基于内源糖苷酶酶解结合树脂吸附脱除白果致毒成分的方法及其制备的产品和应用
CN107647407A (zh) * 2017-11-14 2018-02-02 宜昌东方昌绿茶业有限公司 一种从银杏茶中提取黄酮素的方法
CN113491721B (zh) * 2020-03-19 2022-05-31 江苏得乐康生物科技有限公司 一种脱除银杏叶提取物中银杏毒素的方法
CN115894424B (zh) * 2023-01-06 2023-05-12 中日友好医院(中日友好临床医学研究所) 新型双黄酮类化合物及其制备方法、药物组合物和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2627387B1 (fr) 1988-02-24 1992-06-05 Fabre Sa Pierre Procede d'obtention d'un extrait de feuilles de ginkgo biloba
GB8822004D0 (en) * 1988-09-20 1988-10-19 Indena Spa New extracts of ginkgo biloba & their methods of preparation
DE3940091A1 (de) * 1989-12-04 1991-06-06 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel
JP3518882B2 (ja) 1993-11-12 2004-04-12 ダイセル化学工業株式会社 イチョウエキス及びその製造法
DE19756848C2 (de) * 1997-12-19 2003-01-16 Schwabe Willmar Gmbh & Co Extrakte aus Blättern von Ginkgo biloba mit vermindertem Gehalt an 4'-O-Methylpyridoxin und Biflavonen
US20040076691A1 (en) * 2002-01-16 2004-04-22 David Haines Anti-inflammatory formulations
CN1251675C (zh) * 2004-02-10 2006-04-19 张正生 一种注射用银杏达莫粉针剂及其制备方法
CN100451013C (zh) * 2004-04-21 2009-01-14 徐州技源天然保健品有限公司 一种从卷柏中提取穗花杉双黄酮提取物的生产工艺

Also Published As

Publication number Publication date
ATE401903T1 (de) 2008-08-15
US8642099B2 (en) 2014-02-04
BRPI0611093B1 (pt) 2018-01-16
RU2367459C2 (ru) 2009-09-20
UA84519C2 (ru) 2008-10-27
JP4304230B2 (ja) 2009-07-29
PE20061296A1 (es) 2007-01-06
US20080286391A1 (en) 2008-11-20
CN101175505A (zh) 2008-05-07
JP2009173663A (ja) 2009-08-06
DOP2006000091A (es) 2007-01-31
CA2606843C (en) 2010-05-25
TWI376230B (en) 2012-11-11
TW200716149A (en) 2007-05-01
MX2007013398A (es) 2007-12-07
PT1868625E (pt) 2008-09-22
JP2008540354A (ja) 2008-11-20
EP1868625A1 (en) 2007-12-26
EP1868625B1 (en) 2008-07-23
KR20070112271A (ko) 2007-11-22
DK1868625T3 (da) 2008-11-10
PL1868625T3 (pl) 2009-01-30
NZ563818A (en) 2009-11-27
ES2310408T3 (es) 2009-01-01
WO2006117169A1 (en) 2006-11-09
US20060251746A1 (en) 2006-11-09
CN104189025A (zh) 2014-12-10
KR100933721B1 (ko) 2009-12-24
MY143650A (en) 2011-06-30
AR054270A1 (es) 2007-06-13
AU2006243378A1 (en) 2006-11-09
DE602006001949D1 (de) 2008-09-04
BRPI0611093A2 (pt) 2010-08-10
RU2007143632A (ru) 2009-06-10
SI1868625T1 (sl) 2008-12-31
AU2006243378B2 (en) 2008-03-20
CA2606843A1 (en) 2006-11-09
DE102005061948A1 (de) 2006-11-16

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