IT8567743A0 - Derivati di benzimidazolo procedimento per la loro preparazione e agenti antiulcera che li contengono - Google Patents
Derivati di benzimidazolo procedimento per la loro preparazione e agenti antiulcera che li contengonoInfo
- Publication number
- IT8567743A0 IT8567743A0 IT8567743A IT6774385A IT8567743A0 IT 8567743 A0 IT8567743 A0 IT 8567743A0 IT 8567743 A IT8567743 A IT 8567743A IT 6774385 A IT6774385 A IT 6774385A IT 8567743 A0 IT8567743 A0 IT 8567743A0
- Authority
- IT
- Italy
- Prior art keywords
- antiulcera
- agents
- contain
- preparation
- benzimidazole derivatives
- Prior art date
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 150000001556 benzimidazoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59182400A JPS6160660A (ja) | 1984-08-31 | 1984-08-31 | ベンズイミダゾ−ル誘導体およびその製造法ならびにこれを含有する抗潰瘍剤 |
JP60061195A JPH0764826B2 (ja) | 1985-03-26 | 1985-03-26 | ベンズイミダゾール誘導体 |
JP60061194A JPH068283B2 (ja) | 1985-03-26 | 1985-03-26 | ベンズイミダゾ−ル誘導体およびその製造法ならびにこれを含有する抗潰瘍剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8567743A0 true IT8567743A0 (it) | 1985-08-30 |
IT1189601B IT1189601B (it) | 1988-02-04 |
Family
ID=27297422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT67743/85A IT1189601B (it) | 1984-08-31 | 1985-08-30 | Derivati di benzimidazolo procedimento per la loro preparazione e agenti antiulcera che li contengono |
Country Status (14)
Country | Link |
---|---|
KR (1) | KR920004936B1 (it) |
AR (1) | AR242195A1 (it) |
AU (3) | AU4640985A (it) |
BE (1) | BE903128A (it) |
BR (1) | BR8504252A (it) |
CH (1) | CH665417A5 (it) |
DE (1) | DE3531487C2 (it) |
ES (1) | ES8703142A1 (it) |
FR (1) | FR2569691B1 (it) |
GB (1) | GB2163747B (it) |
IT (1) | IT1189601B (it) |
MX (1) | MX159807A (it) |
NL (1) | NL8502384A (it) |
SE (1) | SE500669C2 (it) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8417194D0 (en) * | 1984-07-05 | 1984-08-08 | Boots Co Plc | Therapeutic agents |
GB2161160B (en) * | 1984-07-06 | 1989-05-24 | Fisons Plc | Heterocyclic sulphinyl compounds |
DE3585252D1 (de) | 1984-07-06 | 1992-03-05 | Fisons Plc | Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen. |
AU5768886A (en) * | 1985-05-24 | 1986-11-27 | G.D. Searle & Co. | 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines |
US5869513A (en) * | 1985-05-24 | 1999-02-09 | G. D. Searle & Co. | 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines |
US4824856A (en) * | 1985-08-14 | 1989-04-25 | Nippon Chemiphar Co., Ltd. | Method of protecting gastrointestinal tract |
WO1987001114A2 (en) * | 1985-08-21 | 1987-02-26 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New amines, process for their manufacture, their use and medicines containing them |
AR243167A1 (es) | 1985-08-24 | 1993-07-30 | Hoechst Ag | Procedimiento para la preparacion de toluidinas sustituidas. |
AU619444B2 (en) * | 1986-06-02 | 1992-01-30 | Nippon Chemiphar Co. Ltd. | 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives |
EP0251536A1 (en) * | 1986-06-24 | 1988-01-07 | FISONS plc | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors |
US4687775A (en) * | 1986-07-17 | 1987-08-18 | G. D. Searle & Co. | 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles |
US4772619A (en) * | 1986-07-17 | 1988-09-20 | G. D. Searle & Co. | [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines |
US4721718A (en) * | 1986-08-18 | 1988-01-26 | G. D. Searle & Co. | 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers |
DE3639926A1 (de) * | 1986-11-22 | 1988-06-01 | Hoechst Ag | Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
IT1222412B (it) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono |
JP2614756B2 (ja) * | 1988-08-10 | 1997-05-28 | 日本ケミファ株式会社 | イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤 |
JPH06298611A (ja) * | 1993-04-16 | 1994-10-25 | Nippon Chemiphar Co Ltd | 抗菌剤 |
SE9301489D0 (sv) | 1993-04-30 | 1993-04-30 | Ab Astra | Veterinary composition |
SE9402431D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
DE69631981T2 (de) * | 1995-09-21 | 2005-04-14 | Pharma Pass Ii Llc, Irvine | Lansoprazolhaltige Arzneizusammensetzung und Herstellungsverfahren |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
US6599927B2 (en) | 1996-10-11 | 2003-07-29 | Astrazeneca Ab | Use of an H+, K+-ATPase inhibitor in the treatment of Widal's Syndrome |
DE69827392T2 (de) | 1997-07-25 | 2005-10-27 | Altana Pharma Ag | Protonenpumpenhemmer als kombinationstherapeutika mit antibakteriell wirkenden substanzen |
SE9704870D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
SE9704869D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
ATE321538T1 (de) | 1998-08-12 | 2006-04-15 | Altana Pharma Ag | Orale darreichungsform für pyridin-2- ylmethylsulfinyl-1h-benzimidazole |
AU1054899A (en) * | 1998-11-06 | 2000-05-29 | Dong-A Pharmaceutical Co., Ltd. | Method of preparing sulfide derivatives |
TWI243672B (en) | 1999-06-01 | 2005-11-21 | Astrazeneca Ab | New use of compounds as antibacterial agents |
PT1187601E (pt) | 1999-06-07 | 2005-11-30 | Altana Pharma Ag | Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido |
SE9903831D0 (sv) * | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
SE0000774D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
SE0102993D0 (sv) | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
DE60325709D1 (de) | 2002-04-09 | 2009-02-26 | Flamel Tech Sa | Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen |
CA2480824A1 (fr) | 2002-04-09 | 2003-10-16 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
KR20060092255A (ko) | 2003-09-26 | 2006-08-22 | 알자 코포레이션 | 고도의 약물적재를 제공하는 약물코팅제 및 그의 제조방법 |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US20060024362A1 (en) | 2004-07-29 | 2006-02-02 | Pawan Seth | Composition comprising a benzimidazole and process for its manufacture |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
CN101453993A (zh) | 2006-04-03 | 2009-06-10 | 伊萨·奥迪迪 | 含有机溶胶涂层的受控释放递送物件 |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
PL2046334T3 (pl) | 2006-07-25 | 2015-02-27 | Vecta Ltd | Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI |
US9205094B2 (en) | 2006-12-22 | 2015-12-08 | Ironwood Pharmaceuticals, Inc. | Compositions comprising bile acid sequestrants for treating esophageal disorders |
AU2009290712A1 (en) | 2008-09-09 | 2010-03-18 | Astrazeneca Ab | Method for delivering a pharmaceutical composition to patient in need thereof |
WO2010151216A1 (en) | 2009-06-25 | 2010-12-29 | Astrazeneca Ab | Method for treating a patient at risk for developing an nsaid-associated ulcer |
WO2011080502A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
EP2519229A2 (en) | 2009-12-29 | 2012-11-07 | Novartis AG | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
WO2011080500A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
EP2601947A1 (en) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
CA2860231A1 (en) | 2011-12-28 | 2013-07-04 | Pozen Inc. | Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid |
EP2945614B1 (en) | 2013-01-15 | 2021-11-24 | Ironwood Pharmaceuticals, Inc. | Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant |
EP2801565B1 (en) * | 2013-05-06 | 2015-07-22 | King Saud University | Compounds for use as anti-ulcer agent and/or anti-Helicobacter pylori agent and pharmaceutical compositions thereof |
WO2016126625A1 (en) | 2015-02-03 | 2016-08-11 | Ironwood Pharmaceuticals, Inc. | Methods of treating upper gastrointestinal disorders in ppi refractory gerd |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
DE3585252D1 (de) * | 1984-07-06 | 1992-03-05 | Fisons Plc | Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen. |
-
1985
- 1985-08-19 AU AU46409/85A patent/AU4640985A/en not_active Abandoned
- 1985-08-27 ES ES546445A patent/ES8703142A1/es not_active Expired
- 1985-08-27 BE BE0/215506A patent/BE903128A/fr not_active IP Right Cessation
- 1985-08-29 GB GB08521493A patent/GB2163747B/en not_active Expired
- 1985-08-29 CH CH3709/85A patent/CH665417A5/fr not_active IP Right Cessation
- 1985-08-30 FR FR858512961A patent/FR2569691B1/fr not_active Expired
- 1985-08-30 KR KR1019850006307A patent/KR920004936B1/ko not_active IP Right Cessation
- 1985-08-30 SE SE8504048A patent/SE500669C2/sv unknown
- 1985-08-30 AR AR85301474A patent/AR242195A1/es active
- 1985-08-30 MX MX206462A patent/MX159807A/es unknown
- 1985-08-30 NL NL8502384A patent/NL8502384A/nl not_active Application Discontinuation
- 1985-08-30 BR BR8504252A patent/BR8504252A/pt unknown
- 1985-08-30 DE DE3531487A patent/DE3531487C2/de not_active Expired - Fee Related
- 1985-08-30 IT IT67743/85A patent/IT1189601B/it active
-
1989
- 1989-09-11 AU AU41271/89A patent/AU4127189A/en not_active Abandoned
-
1992
- 1992-11-27 AU AU29750/92A patent/AU647978B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU2975092A (en) | 1993-01-28 |
ES546445A0 (es) | 1986-11-16 |
FR2569691B1 (fr) | 1989-08-04 |
NL8502384A (nl) | 1986-03-17 |
DE3531487C2 (de) | 1995-08-17 |
KR920004936B1 (ko) | 1992-06-22 |
GB2163747A (en) | 1986-03-05 |
AR242195A1 (es) | 1993-03-31 |
MX159807A (es) | 1989-08-31 |
SE8504048D0 (sv) | 1985-08-30 |
BR8504252A (pt) | 1986-06-17 |
AU647978B2 (en) | 1994-03-31 |
GB8521493D0 (en) | 1985-10-02 |
FR2569691A1 (fr) | 1986-03-07 |
IT1189601B (it) | 1988-02-04 |
SE500669C2 (sv) | 1994-08-08 |
AU4640985A (en) | 1986-03-06 |
SE8504048L (sv) | 1986-03-01 |
DE3531487A1 (de) | 1986-03-13 |
KR860001793A (ko) | 1986-03-22 |
AU4127189A (en) | 1989-12-21 |
BE903128A (fr) | 1985-12-16 |
CH665417A5 (fr) | 1988-05-13 |
GB2163747B (en) | 1989-02-08 |
ES8703142A1 (es) | 1986-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19990331 |