ES8703142A1 - Proceso para preparar un derivado del bencimidazol. - Google Patents

Proceso para preparar un derivado del bencimidazol.

Info

Publication number
ES8703142A1
ES8703142A1 ES546445A ES546445A ES8703142A1 ES 8703142 A1 ES8703142 A1 ES 8703142A1 ES 546445 A ES546445 A ES 546445A ES 546445 A ES546445 A ES 546445A ES 8703142 A1 ES8703142 A1 ES 8703142A1
Authority
ES
Spain
Prior art keywords
benzimidazole derivatives
alkyl
hydrogen
alkoxycarbonyl
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546445A
Other languages
English (en)
Other versions
ES546445A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59182400A external-priority patent/JPS6160660A/ja
Priority claimed from JP60061194A external-priority patent/JPH068283B2/ja
Priority claimed from JP60061195A external-priority patent/JPH0764826B2/ja
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Publication of ES546445A0 publication Critical patent/ES546445A0/es
Publication of ES8703142A1 publication Critical patent/ES8703142A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE BENCIMIDAZOL. SE HACE REACCIONAR UN 2-MERCAPTOBENCIMIDAZOL DE FORMULA (II) CON UN COMPUESTO DE 2-AMINOBENCILO DE FORMULA (II) PARA DAR UN COMPUESTO QUE POR OXIDACION PROPORCIONA UN DERIVADO DE BENCIMIDAZOL DE FORMULA (I). ESTOS DERIVADOS SON APLICABLES PARA LA SUPRESION DE LA SECRECION DE ACIDO GASTRICO.
ES546445A 1984-08-31 1985-08-27 Proceso para preparar un derivado del bencimidazol. Expired ES8703142A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP59182400A JPS6160660A (ja) 1984-08-31 1984-08-31 ベンズイミダゾ−ル誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JP60061194A JPH068283B2 (ja) 1985-03-26 1985-03-26 ベンズイミダゾ−ル誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JP60061195A JPH0764826B2 (ja) 1985-03-26 1985-03-26 ベンズイミダゾール誘導体

Publications (2)

Publication Number Publication Date
ES546445A0 ES546445A0 (es) 1986-11-16
ES8703142A1 true ES8703142A1 (es) 1986-11-16

Family

ID=27297422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546445A Expired ES8703142A1 (es) 1984-08-31 1985-08-27 Proceso para preparar un derivado del bencimidazol.

Country Status (14)

Country Link
KR (1) KR920004936B1 (es)
AR (1) AR242195A1 (es)
AU (3) AU4640985A (es)
BE (1) BE903128A (es)
BR (1) BR8504252A (es)
CH (1) CH665417A5 (es)
DE (1) DE3531487C2 (es)
ES (1) ES8703142A1 (es)
FR (1) FR2569691B1 (es)
GB (1) GB2163747B (es)
IT (1) IT1189601B (es)
MX (1) MX159807A (es)
NL (1) NL8502384A (es)
SE (1) SE500669C2 (es)

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US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
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IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
JP2614756B2 (ja) * 1988-08-10 1997-05-28 日本ケミファ株式会社 イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
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SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5708017A (en) * 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
PT859612E (pt) * 1995-09-21 2003-10-31 Pharma Pass Ii Llc Composicao farmaceutica contendo um omeprazol acid-labil e um processo para a sua preparacao
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
US6599927B2 (en) 1996-10-11 2003-07-29 Astrazeneca Ab Use of an H+, K+-ATPase inhibitor in the treatment of Widal's Syndrome
ATE281178T1 (de) 1997-07-25 2004-11-15 Altana Pharma Ag Protonenpumpenhemmer als kombinationstherapeutika mit antibakterielle wirkenden substanzen
SE9704870D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
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DE69930648T2 (de) 1998-08-12 2006-12-21 Altana Pharma Ag Orale darreichungsform für pyridin-2-ylmethylsulfinyl-1h-benzimidazole
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SE9903831D0 (sv) 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
WO2003084517A2 (fr) 2002-04-09 2003-10-16 Flamel Technologies Suspension orale de microcapsules d’amoxicilline
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
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CA1341314C (en) * 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole

Also Published As

Publication number Publication date
GB8521493D0 (en) 1985-10-02
AU4640985A (en) 1986-03-06
AU647978B2 (en) 1994-03-31
GB2163747B (en) 1989-02-08
BR8504252A (pt) 1986-06-17
SE8504048L (sv) 1986-03-01
KR860001793A (ko) 1986-03-22
ES546445A0 (es) 1986-11-16
NL8502384A (nl) 1986-03-17
KR920004936B1 (ko) 1992-06-22
IT8567743A0 (it) 1985-08-30
SE500669C2 (sv) 1994-08-08
SE8504048D0 (sv) 1985-08-30
FR2569691B1 (fr) 1989-08-04
DE3531487C2 (de) 1995-08-17
AR242195A1 (es) 1993-03-31
IT1189601B (it) 1988-02-04
AU2975092A (en) 1993-01-28
BE903128A (fr) 1985-12-16
GB2163747A (en) 1986-03-05
DE3531487A1 (de) 1986-03-13
CH665417A5 (fr) 1988-05-13
AU4127189A (en) 1989-12-21
MX159807A (es) 1989-08-31
FR2569691A1 (fr) 1986-03-07

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