BR8504252A - Derivado de benzimidazol,processo para a preparacao de um derivado de benzimidazol e um agente anti ulceroso - Google Patents

Derivado de benzimidazol,processo para a preparacao de um derivado de benzimidazol e um agente anti ulceroso

Info

Publication number
BR8504252A
BR8504252A BR8504252A BR8504252A BR8504252A BR 8504252 A BR8504252 A BR 8504252A BR 8504252 A BR8504252 A BR 8504252A BR 8504252 A BR8504252 A BR 8504252A BR 8504252 A BR8504252 A BR 8504252A
Authority
BR
Brazil
Prior art keywords
benzimidazol
derivative
ulcerosal
agent
preparation
Prior art date
Application number
BR8504252A
Other languages
English (en)
Inventor
Susumu Okabe
Masaru Satoh
Tomio Yamakawa
Yutaka Nomura
Masatoshi Hayashi
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59182400A external-priority patent/JPS6160660A/ja
Priority claimed from JP60061194A external-priority patent/JPH068283B2/ja
Priority claimed from JP60061195A external-priority patent/JPH0764826B2/ja
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of BR8504252A publication Critical patent/BR8504252A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR8504252A 1984-08-31 1985-08-30 Derivado de benzimidazol,processo para a preparacao de um derivado de benzimidazol e um agente anti ulceroso BR8504252A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP59182400A JPS6160660A (ja) 1984-08-31 1984-08-31 ベンズイミダゾ−ル誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JP60061194A JPH068283B2 (ja) 1985-03-26 1985-03-26 ベンズイミダゾ−ル誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JP60061195A JPH0764826B2 (ja) 1985-03-26 1985-03-26 ベンズイミダゾール誘導体

Publications (1)

Publication Number Publication Date
BR8504252A true BR8504252A (pt) 1986-06-17

Family

ID=27297422

Family Applications (1)

Application Number Title Priority Date Filing Date
BR8504252A BR8504252A (pt) 1984-08-31 1985-08-30 Derivado de benzimidazol,processo para a preparacao de um derivado de benzimidazol e um agente anti ulceroso

Country Status (14)

Country Link
KR (1) KR920004936B1 (pt)
AR (1) AR242195A1 (pt)
AU (3) AU4640985A (pt)
BE (1) BE903128A (pt)
BR (1) BR8504252A (pt)
CH (1) CH665417A5 (pt)
DE (1) DE3531487C2 (pt)
ES (1) ES8703142A1 (pt)
FR (1) FR2569691B1 (pt)
GB (1) GB2163747B (pt)
IT (1) IT1189601B (pt)
MX (1) MX159807A (pt)
NL (1) NL8502384A (pt)
SE (1) SE500669C2 (pt)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
CA1341314C (en) 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
EP0204215B1 (en) * 1985-05-24 1993-08-11 G.D. Searle & Co. 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-benzenamines
US4824856A (en) * 1985-08-14 1989-04-25 Nippon Chemiphar Co., Ltd. Method of protecting gastrointestinal tract
WO1987001114A2 (en) * 1985-08-21 1987-02-26 Byk Gulden Lomberg Chemische Fabrik Gmbh New amines, process for their manufacture, their use and medicines containing them
AR243167A1 (es) 1985-08-24 1993-07-30 Hoechst Ag Procedimiento para la preparacion de toluidinas sustituidas.
AU619444B2 (en) * 1986-06-02 1992-01-30 Nippon Chemiphar Co. Ltd. 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives
EP0251536A1 (en) * 1986-06-24 1988-01-07 FISONS plc Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
JP2614756B2 (ja) * 1988-08-10 1997-05-28 日本ケミファ株式会社 イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JPH06298611A (ja) * 1993-04-16 1994-10-25 Nippon Chemiphar Co Ltd 抗菌剤
SE9301489D0 (sv) 1993-04-30 1993-04-30 Ab Astra Veterinary composition
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5708017A (en) * 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
PL186605B1 (pl) * 1995-09-21 2004-01-30 Pharma Pass Llc Tabletka lub mikrotabletka zawierająca rdzeń posiadający jako kwasolabilny składnik aktywny omeprazol oraz sposób wytwarzania tabletek lub mikrotabletek zawierających rdzeń posiadający jako kwasolabilny składnik aktywny omeprazol
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
US6380222B2 (en) 1996-10-11 2002-04-30 Astrazeneca Ab Use of an H+, K+-atpase inhibitor in the treatment of nasal polyps
EP1003554B1 (en) 1997-07-25 2004-11-03 ALTANA Pharma AG Proton pump inhibitor in therapeutic combination with antibacterial substances
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
SE9704870D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
SI1105105T1 (sl) 1998-08-12 2006-08-31 Altana Pharma Ag Oralna dajalna oblika za piridin-2-ilmetilsulfinil-1J-benzimidazole
AU1054899A (en) * 1998-11-06 2000-05-29 Dong-A Pharmaceutical Co., Ltd. Method of preparing sulfide derivatives
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
ATE300285T1 (de) 1999-06-07 2005-08-15 Altana Pharma Ag Neue zubereitung und darreichungsform enthaltend einen säurelabilen protonenpumpeninhibitor
SE9903831D0 (sv) 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
CA2480824A1 (fr) 2002-04-09 2003-10-16 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
MXPA06003450A (es) 2003-09-26 2006-08-31 Johnson & Johnson Recubrimiento de farmaco que proporciona alta carga del farmaco y metodos para proporcionar el mismo.
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
WO2007112581A1 (en) 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
EP2046334B1 (en) 2006-07-25 2014-05-21 Vecta Ltd. Compositions and meth0ds for inhibiting gastric acide secretion using derivatives of small dicarboxylic acids in combination with ppi
SI2124884T1 (sl) 2006-12-22 2019-09-30 Ironwood Pharmaceuticals, Inc. Pripravki, ki obsegajo sekvestrante žolčnih kislin, za zdravljenje motenj požiralnika
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080501A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
EP2601947A1 (en) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Fixed-dose combination for treatment of helicobacter pylori associated diseases
CA2860231A1 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
WO2014113377A1 (en) 2013-01-15 2014-07-24 Ironwood Pharmaceuticals, Inc. Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant
EP2801565B1 (en) * 2013-05-06 2015-07-22 King Saud University Compounds for use as anti-ulcer agent and/or anti-Helicobacter pylori agent and pharmaceutical compositions thereof
WO2016126625A1 (en) 2015-02-03 2016-08-11 Ironwood Pharmaceuticals, Inc. Methods of treating upper gastrointestinal disorders in ppi refractory gerd

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CA1341314C (en) * 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole

Also Published As

Publication number Publication date
FR2569691A1 (fr) 1986-03-07
CH665417A5 (fr) 1988-05-13
GB8521493D0 (en) 1985-10-02
IT8567743A0 (it) 1985-08-30
GB2163747A (en) 1986-03-05
SE500669C2 (sv) 1994-08-08
KR920004936B1 (ko) 1992-06-22
SE8504048L (sv) 1986-03-01
AU647978B2 (en) 1994-03-31
NL8502384A (nl) 1986-03-17
GB2163747B (en) 1989-02-08
BE903128A (fr) 1985-12-16
ES546445A0 (es) 1986-11-16
ES8703142A1 (es) 1986-11-16
AU4127189A (en) 1989-12-21
MX159807A (es) 1989-08-31
DE3531487C2 (de) 1995-08-17
AU2975092A (en) 1993-01-28
DE3531487A1 (de) 1986-03-13
IT1189601B (it) 1988-02-04
AU4640985A (en) 1986-03-06
FR2569691B1 (fr) 1989-08-04
AR242195A1 (es) 1993-03-31
KR860001793A (ko) 1986-03-22
SE8504048D0 (sv) 1985-08-30

Similar Documents

Publication Publication Date Title
BR8504252A (pt) Derivado de benzimidazol,processo para a preparacao de um derivado de benzimidazol e um agente anti ulceroso
BR9004522A (pt) Processo para a preparacao de um agente aromatizante
PT80859B (pt) Processo para a preparacao de derivados de glutarimida que sao agentes ansioliticos e anti-hipertensores
BR8505734A (pt) Processo para a preparacao de acidos alquil-1-ciclopropil-1,4-dihidro-4-oxo-3-quinolinocarboxilicos,e aplicacao
BR8801797A (pt) Agente de revestimento aquoso,processo para sua preparacao e aplicacao
BR8206567A (pt) Processo para preparacao de 4,4'-diisocianatodifenilmetano
BR8200741A (pt) Composto,emprego e processo de preparacao de compostos
BR8205890A (pt) Processo para a preparacao de composicoes termofixas e composicao termofixa
BR8706915A (pt) Processo para a preparacao de derivados metoxibenzofenona,metoxibenzofenonas e composto
PT89204A (pt) Processo para a preparacao de um agente edulcorante
BR8201857A (pt) Processo para preparacao de dissulfetos de ditiazolila
PT80919B (pt) Processo para a preparacao de 3-arilcarbonil e 3-cicloalquilcarbonil-1-minoalquil_1h-indois
BR8207708A (pt) Lingoteira e processo para formacao da mesma
BR8505941A (pt) Processo para a preparacao de poliisocianatos organicos modificados,poliisocianatos e aplicacao
BR8400690A (pt) Processo para a preparacao de eter-sulfonatos,eter-sulfonatos de tributilfenol,e aplicacao dos ultimos
BR8800392A (pt) 2-imino-1,3-ditietanos,processo para a preparacao de compostos,aplicacao e composicoes praguicidas
BR8104544A (pt) Processo para a preparacao de fanilureiras ,composicoes praguicidas e emprego
BR9002830A (pt) Agente formicida para o combate de termitas,processo para o combate de termitas,uso e processo para a preparacao de agentes formicidas para o combate de termitas
BR8602376A (pt) Processo para a preparacao de derivados de diclorociclopropilalquil-hidroxialquil-azol,composicoes fungicidas,processos para combater fungos e para a preparacao de composicoes e processo para a preparacao de derivados de azolilcetona
BR8804788A (pt) Composicao,aplicacao e processo para a preparacao de compostos
BR8606248A (pt) Processo para a preparacao de derivados de 1-azolil-3,3-dimetil-butano-2-ona e-2-ol 1,4-dissubstituidos,composicoes fungicidas,metodo de combate de fungos e para a preparacao de composicoes
BR8905815A (pt) Processo para preparacao de cetoximossilanos
PT81157B (pt) Processo para a preparacao de aromatico-1,4-oxazepinonas e tionas
BR8504156A (pt) Processo para a preparacao de derivados de sulfonilguani-dinotriazina,composicoes herbicidas,aplicacao,processo para a preparacao de composicoes e processo para a preparacao de derivados de sulfonilisou-reidotriazina
BR8303200A (pt) Processo para a preparacao de um derivado de benzilureia, e composicoes fungicidas