IT1212097B - Sintesi dell'aspartame. - Google Patents

Sintesi dell'aspartame.

Info

Publication number
IT1212097B
IT1212097B IT8421147A IT2114784A IT1212097B IT 1212097 B IT1212097 B IT 1212097B IT 8421147 A IT8421147 A IT 8421147A IT 2114784 A IT2114784 A IT 2114784A IT 1212097 B IT1212097 B IT 1212097B
Authority
IT
Italy
Prior art keywords
aspartame
Prior art date
Application number
IT8421147A
Other languages
English (en)
Other versions
IT8421147A0 (it
Inventor
Pietro Giardino
Ernesto Oppici
Franco Dallatomasina
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of IT8421147A0 publication Critical patent/IT8421147A0/it
Application granted granted Critical
Publication of IT1212097B publication Critical patent/IT1212097B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT8421147A 1983-05-31 1984-05-29 Sintesi dell'aspartame. IT1212097B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838314907A GB8314907D0 (en) 1983-05-31 1983-05-31 Aspartame synthesis

Publications (2)

Publication Number Publication Date
IT8421147A0 IT8421147A0 (it) 1984-05-29
IT1212097B true IT1212097B (it) 1989-11-08

Family

ID=10543585

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8421147A IT1212097B (it) 1983-05-31 1984-05-29 Sintesi dell'aspartame.

Country Status (29)

Country Link
US (1) US4656304A (it)
JP (1) JPS59227850A (it)
KR (1) KR910002387B1 (it)
AT (1) AT387024B (it)
AU (1) AU561593B2 (it)
BE (1) BE899783A (it)
CA (1) CA1244008A (it)
CH (1) CH659061A5 (it)
CS (1) CS257778B2 (it)
DE (1) DE3419921A1 (it)
DK (1) DK163928C (it)
ES (1) ES532916A0 (it)
FI (1) FI80465C (it)
FR (1) FR2547816B1 (it)
GB (1) GB8314907D0 (it)
GR (1) GR82034B (it)
HU (1) HU191146B (it)
IE (2) IE810577L (it)
IL (1) IL71930A (it)
IT (1) IT1212097B (it)
NL (1) NL192112C (it)
NO (1) NO163738C (it)
NZ (1) NZ208279A (it)
PH (1) PH21764A (it)
PT (1) PT78657B (it)
SE (1) SE459176B (it)
SU (1) SU1342423A3 (it)
YU (1) YU44456B (it)
ZA (1) ZA844071B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0680075B2 (ja) * 1985-12-24 1994-10-12 味の素株式会社 Ｎ―ホルミル―α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの製造法
JP2662287B2 (ja) * 1988-03-14 1997-10-08 三井東圧化学株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの分離方法
US5283357A (en) * 1988-03-14 1994-02-01 Mitsui Toatsu Chemicals, Incorporated Separation method of α-l-aspartyl-l-phenylalanine methyl ester
US5017690A (en) * 1989-08-11 1991-05-21 W. R. Grace & Co.-Conn. Deblocking N-formyl aspartame compounds
NL9201408A (nl) * 1992-08-05 1994-03-01 Holland Sweetener Co Werkwijze voor het kristalliseren van aspartaam.
BE1010071A3 (nl) * 1996-04-10 1997-12-02 Holland Sweetener Co Aspartaam op drager.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3833553A (en) * 1970-01-31 1974-09-03 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine alkyl esters
JPS5140069B1 (it) * 1971-07-09 1976-11-01
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
JPS5113737A (en) * 1974-07-23 1976-02-03 Ajinomoto Kk Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
JPS57131746A (en) * 1981-02-10 1982-08-14 Ajinomoto Co Inc Removal of n-formyl group
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法

Also Published As

Publication number Publication date
ZA844071B (en) 1984-12-24
GB8314907D0 (en) 1983-07-06
JPS59227850A (ja) 1984-12-21
KR850000030A (ko) 1985-02-25
HUT34434A (en) 1985-03-28
FR2547816A1 (fr) 1984-12-28
NL192112B (nl) 1996-10-01
AU561593B2 (en) 1987-05-14
YU92284A (en) 1986-10-31
JPH0570638B2 (it) 1993-10-05
FI80465B (fi) 1990-02-28
PT78657A (en) 1984-06-01
SE8402953D0 (sv) 1984-05-30
YU44456B (en) 1990-08-31
ES8506598A1 (es) 1985-08-01
AU2876784A (en) 1984-12-06
ES532916A0 (es) 1985-08-01
PH21764A (en) 1988-02-18
DK163928B (da) 1992-04-21
US4656304A (en) 1987-04-07
FR2547816B1 (fr) 1987-10-30
SE8402953L (sv) 1984-12-01
KR910002387B1 (ko) 1991-04-20
CS257778B2 (en) 1988-06-15
DE3419921C2 (it) 1989-04-20
NO163738B (no) 1990-04-02
GR82034B (it) 1984-12-12
IE841312L (en) 1984-11-30
SE459176B (sv) 1989-06-12
HU191146B (en) 1987-01-28
FI80465C (fi) 1990-06-11
DK270084D0 (da) 1984-05-30
IL71930A (en) 1986-12-31
IT8421147A0 (it) 1984-05-29
NL192112C (nl) 1997-02-04
IL71930A0 (en) 1984-09-30
DK163928C (da) 1992-09-14
BE899783A (fr) 1984-09-17
ATA172384A (de) 1988-04-15
DK270084A (da) 1984-12-01
IE57662B1 (en) 1993-02-24
FI841952A0 (fi) 1984-05-15
CS399884A2 (en) 1987-11-12
CA1244008A (en) 1988-11-01
NO842129L (no) 1984-12-03
FI841952A (fi) 1984-12-01
CH659061A5 (it) 1986-12-31
DE3419921A1 (de) 1984-12-13
SU1342423A3 (ru) 1987-09-30
AT387024B (de) 1988-11-25
IE810577L (en) 1982-09-16
PT78657B (en) 1986-09-08
NO163738C (no) 1990-07-11
NZ208279A (en) 1987-04-30
NL8401674A (nl) 1984-12-17

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960527