DK163928C - Fremgangsmaade til fremstilling af n-l-alfa-aspartyl-l-phenylalanin-methylester (aspartam) - Google Patents
Fremgangsmaade til fremstilling af n-l-alfa-aspartyl-l-phenylalanin-methylester (aspartam)Info
- Publication number
- DK163928C DK163928C DK270084A DK270084A DK163928C DK 163928 C DK163928 C DK 163928C DK 270084 A DK270084 A DK 270084A DK 270084 A DK270084 A DK 270084A DK 163928 C DK163928 C DK 163928C
- Authority
- DK
- Denmark
- Prior art keywords
- aspartam
- aspartyl
- alfa
- preparing
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838314907A GB8314907D0 (en) | 1983-05-31 | 1983-05-31 | Aspartame synthesis |
| GB8314907 | 1983-05-31 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK270084D0 DK270084D0 (da) | 1984-05-30 |
| DK270084A DK270084A (da) | 1984-12-01 |
| DK163928B DK163928B (da) | 1992-04-21 |
| DK163928C true DK163928C (da) | 1992-09-14 |
Family
ID=10543585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK270084A DK163928C (da) | 1983-05-31 | 1984-05-30 | Fremgangsmaade til fremstilling af n-l-alfa-aspartyl-l-phenylalanin-methylester (aspartam) |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US4656304A (da) |
| JP (1) | JPS59227850A (da) |
| KR (1) | KR910002387B1 (da) |
| AT (1) | AT387024B (da) |
| AU (1) | AU561593B2 (da) |
| BE (1) | BE899783A (da) |
| CA (1) | CA1244008A (da) |
| CH (1) | CH659061A5 (da) |
| CS (1) | CS257778B2 (da) |
| DE (1) | DE3419921A1 (da) |
| DK (1) | DK163928C (da) |
| ES (1) | ES532916A0 (da) |
| FI (1) | FI80465C (da) |
| FR (1) | FR2547816B1 (da) |
| GB (1) | GB8314907D0 (da) |
| GR (1) | GR82034B (da) |
| HU (1) | HU191146B (da) |
| IE (2) | IE810577L (da) |
| IL (1) | IL71930A (da) |
| IT (1) | IT1212097B (da) |
| NL (1) | NL192112C (da) |
| NO (1) | NO163738C (da) |
| NZ (1) | NZ208279A (da) |
| PH (1) | PH21764A (da) |
| PT (1) | PT78657B (da) |
| SE (1) | SE459176B (da) |
| SU (1) | SU1342423A3 (da) |
| YU (1) | YU44456B (da) |
| ZA (1) | ZA844071B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0680075B2 (ja) * | 1985-12-24 | 1994-10-12 | 味の素株式会社 | Ｎ―ホルミル―α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの製造法 |
| JP2662287B2 (ja) * | 1988-03-14 | 1997-10-08 | 三井東圧化学株式会社 | α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの分離方法 |
| US5283357A (en) * | 1988-03-14 | 1994-02-01 | Mitsui Toatsu Chemicals, Incorporated | Separation method of α-l-aspartyl-l-phenylalanine methyl ester |
| US5017690A (en) * | 1989-08-11 | 1991-05-21 | W. R. Grace & Co.-Conn. | Deblocking N-formyl aspartame compounds |
| NL9201408A (nl) * | 1992-08-05 | 1994-03-01 | Holland Sweetener Co | Werkwijze voor het kristalliseren van aspartaam. |
| BE1010071A3 (nl) * | 1996-04-10 | 1997-12-02 | Holland Sweetener Co | Aspartaam op drager. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3492131A (en) * | 1966-04-18 | 1970-01-27 | Searle & Co | Peptide sweetening agents |
| JPS5140069B1 (da) * | 1971-07-09 | 1976-11-01 | ||
| US3833553A (en) * | 1970-01-31 | 1974-09-03 | Ajinomoto Kk | Method of producing alpha-l-aspartyl-l-phenylalanine alkyl esters |
| BE791544A (fr) * | 1971-11-19 | 1973-05-17 | Stamicarbon | Preparation d'esters alkyliques de dipeptide |
| JPS5113737A (en) * | 1974-07-23 | 1976-02-03 | Ajinomoto Kk | Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho |
| JPS5223001A (en) * | 1975-08-14 | 1977-02-21 | Ajinomoto Co Inc | Process for elimination of formyl group |
| US4173562A (en) * | 1976-12-27 | 1979-11-06 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester |
| JPS57131746A (en) * | 1981-02-10 | 1982-08-14 | Ajinomoto Co Inc | Removal of n-formyl group |
| JPS58185545A (ja) * | 1982-04-22 | 1983-10-29 | Ajinomoto Co Inc | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法 |
-
1981
- 1981-03-16 IE IE810577A patent/IE810577L/xx unknown
-
1983
- 1983-05-31 GB GB838314907A patent/GB8314907D0/en active Pending
-
1984
- 1984-05-15 FI FI841952A patent/FI80465C/fi not_active IP Right Cessation
- 1984-05-24 GR GR74819A patent/GR82034B/el unknown
- 1984-05-24 FR FR8408119A patent/FR2547816B1/fr not_active Expired
- 1984-05-24 AT AT0172384A patent/AT387024B/de not_active IP Right Cessation
- 1984-05-25 IE IE1312/84A patent/IE57662B1/en not_active IP Right Cessation
- 1984-05-25 NZ NZ208279A patent/NZ208279A/en unknown
- 1984-05-25 US US06/614,150 patent/US4656304A/en not_active Expired - Fee Related
- 1984-05-25 NL NL8401674A patent/NL192112C/nl not_active IP Right Cessation
- 1984-05-25 SU SU843743902A patent/SU1342423A3/ru active
- 1984-05-25 IL IL71930A patent/IL71930A/xx unknown
- 1984-05-25 CA CA000455169A patent/CA1244008A/en not_active Expired
- 1984-05-28 DE DE3419921A patent/DE3419921A1/de active Granted
- 1984-05-28 CS CS843998A patent/CS257778B2/cs unknown
- 1984-05-28 AU AU28767/84A patent/AU561593B2/en not_active Ceased
- 1984-05-28 PT PT78657A patent/PT78657B/pt not_active IP Right Cessation
- 1984-05-28 HU HU842057A patent/HU191146B/hu not_active IP Right Cessation
- 1984-05-29 BE BE0/213030A patent/BE899783A/fr not_active IP Right Cessation
- 1984-05-29 ZA ZA844071A patent/ZA844071B/xx unknown
- 1984-05-29 PH PH30733A patent/PH21764A/en unknown
- 1984-05-29 ES ES532916A patent/ES532916A0/es active Granted
- 1984-05-29 JP JP59107667A patent/JPS59227850A/ja active Granted
- 1984-05-29 IT IT8421147A patent/IT1212097B/it active
- 1984-05-29 NO NO842129A patent/NO163738C/no unknown
- 1984-05-29 CH CH2630/84A patent/CH659061A5/it not_active IP Right Cessation
- 1984-05-30 SE SE8402953A patent/SE459176B/sv not_active IP Right Cessation
- 1984-05-30 KR KR1019840002999A patent/KR910002387B1/ko not_active IP Right Cessation
- 1984-05-30 YU YU922/84A patent/YU44456B/xx unknown
- 1984-05-30 DK DK270084A patent/DK163928C/da not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |