IS2289B - Úðagjöf á virkum efnum með mótstöðustýrðu flæði - Google Patents

Úðagjöf á virkum efnum með mótstöðustýrðu flæði

Info

Publication number
IS2289B
IS2289B IS5904A IS5904A IS2289B IS 2289 B IS2289 B IS 2289B IS 5904 A IS5904 A IS 5904A IS 5904 A IS5904 A IS 5904A IS 2289 B IS2289 B IS 2289B
Authority
IS
Iceland
Prior art keywords
spraying
resistance
active substances
controlled flow
controlled
Prior art date
Application number
IS5904A
Other languages
English (en)
Other versions
IS5904A (is
Inventor
Clark Andrew
Schuler Carlos
Paboojian Steve
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Publication of IS5904A publication Critical patent/IS5904A/is
Publication of IS2289B publication Critical patent/IS2289B/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • Illuminated Signs And Luminous Advertising (AREA)
  • Soft Magnetic Materials (AREA)
  • Paints Or Removers (AREA)
IS5904A 1998-10-09 2001-03-21 Úðagjöf á virkum efnum með mótstöðustýrðu flæði IS2289B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10370298P 1998-10-09 1998-10-09
PCT/US1999/023698 WO2000021594A2 (en) 1998-10-09 1999-10-07 Flow resistance modulated aerosolized active agent delivery

Publications (2)

Publication Number Publication Date
IS5904A IS5904A (is) 2001-03-21
IS2289B true IS2289B (is) 2007-10-15

Family

ID=22296604

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5904A IS2289B (is) 1998-10-09 2001-03-21 Úðagjöf á virkum efnum með mótstöðustýrðu flæði

Country Status (50)

Country Link
US (1) US8408200B2 (is)
EP (1) EP1119384B1 (is)
JP (2) JP4378057B2 (is)
KR (1) KR100652532B1 (is)
CN (2) CN101804230B (is)
AP (1) AP1646A (is)
AR (1) AR020760A1 (is)
AT (1) ATE297771T1 (is)
AU (1) AU754724B2 (is)
BG (1) BG105377A (is)
BR (1) BR9914384A (is)
CA (1) CA2346791C (is)
CO (1) CO5060481A1 (is)
CZ (1) CZ20011181A3 (is)
DE (1) DE69925849T2 (is)
DK (1) DK1119384T3 (is)
DZ (1) DZ2906A1 (is)
EA (1) EA003405B1 (is)
EE (1) EE04608B1 (is)
EG (1) EG22111A (is)
ES (1) ES2243094T3 (is)
GE (1) GEP20043259B (is)
GT (1) GT199900174A (is)
HK (1) HK1040645B (is)
HR (1) HRP20010253B1 (is)
HU (1) HU225057B1 (is)
ID (1) ID28354A (is)
IL (1) IL142215A (is)
IS (1) IS2289B (is)
LT (2) LT4902B (is)
LV (1) LV12685B (is)
MA (1) MA25865A1 (is)
MY (1) MY129112A (is)
NO (1) NO20011742L (is)
NZ (1) NZ510853A (is)
OA (1) OA11791A (is)
PA (1) PA8484001A1 (is)
PE (1) PE20001281A1 (is)
PL (1) PL193881B1 (is)
PT (1) PT1119384E (is)
RO (1) RO120532B1 (is)
RS (1) RS49848B (is)
SA (1) SA99200835B1 (is)
SK (1) SK287044B6 (is)
TN (1) TNSN99188A1 (is)
TR (1) TR200101033T2 (is)
UA (1) UA73924C2 (is)
UY (1) UY25731A1 (is)
WO (1) WO2000021594A2 (is)
ZA (1) ZA200102766B (is)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
WO2001085136A2 (en) 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
GB2380946A (en) * 2001-08-31 2003-04-23 Medic Aid Ltd Nebuliser arrangement
WO2003043585A2 (en) 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
JP2005514393A (ja) 2001-12-19 2005-05-19 ネクター セラピューティクス アミノグリコシドの肺への供給
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
JP4286498B2 (ja) * 2002-05-14 2009-07-01 アクティヴァエロ ゲーエムベーハー エアロゾルを管理するための装置
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
WO2004060966A2 (en) 2002-12-31 2004-07-22 Nektar Therapeutics Al, Corporation Maleamic acid polymer derivatives and their bioconjugates
US7790835B2 (en) 2003-12-03 2010-09-07 Nektar Therapeutics Method of preparing maleimide functionalized polymers
US9022027B2 (en) 2004-02-20 2015-05-05 Pneumoflex Systems, Llc Nebulizer with intra-oral vibrating mesh
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
US7832394B2 (en) * 2004-12-22 2010-11-16 Schechter Alan M Apparatus for dispensing pressurized contents
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
RU2311204C2 (ru) * 2005-10-04 2007-11-27 Евгений Александрович Оленев Способ введения аэрозольного препарата
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
TW200911311A (en) 2007-06-15 2009-03-16 Boehringer Ingelheim Int Inhaler
EP2082762A1 (en) 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhaler
GB0802028D0 (en) * 2008-02-05 2008-03-12 Dunne Stephen T Powder inhaler flow regulator
AU2009228074B2 (en) * 2008-03-27 2015-01-22 Mannkind Corporation A dry powder inhalation system
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
CA2822738C (en) 2010-12-22 2021-06-08 Exonoid Medical Devices Ltd. Method and system for drug delivery
US8671934B2 (en) 2011-01-20 2014-03-18 Pneumoflex Systems, Llc Nebulizer that is activated by negative inspiratory pressure
US20140207016A1 (en) 2011-01-20 2014-07-24 Pneumoflex Systems, Llc Pulsed nebulizer
US9452270B2 (en) 2011-01-20 2016-09-27 Pneumoflex Systems, Llc Nebulizer having replaceable nozzle assembly and suction line
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
AU2013352004B2 (en) * 2012-11-28 2019-02-14 Fontem Holdings 1 B.V. Methods and devices for compound delivery
US10034988B2 (en) 2012-11-28 2018-07-31 Fontem Holdings I B.V. Methods and devices for compound delivery
CA2898700C (en) 2013-03-14 2022-07-19 Novartis Ag Deamorphization of spray-dried formulations via spray-blending
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10194693B2 (en) 2013-09-20 2019-02-05 Fontem Holdings 1 B.V. Aerosol generating device
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
MX2017000057A (es) 2014-06-30 2017-06-30 Syqe Medical Ltd Procedimiento y dispositivo para vaporizacion e inhalacion de sustancias aisladas.
BR112016030829B1 (pt) 2014-06-30 2022-02-22 Syqe Medical Ltd Cartucho de dosagem para dispositivo inalador
WO2016001922A1 (en) 2014-06-30 2016-01-07 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
CA3215815A1 (en) * 2014-06-30 2016-01-07 Syqe Medical Ltd. Method and device for vaporization and inhalation of isolated substances
IL294075A (en) 2014-06-30 2022-08-01 Syqe Medical Ltd Flow regulating inhaler
EP3160565B1 (en) 2014-06-30 2021-08-18 Syqe Medical Ltd. Devices and systems for pulmonary delivery of active agents
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
US10245393B2 (en) * 2014-08-13 2019-04-02 Elwha Llc Methods, systems, and devices related to a supplemental inhaler
US10987048B2 (en) 2014-08-13 2021-04-27 Elwha Llc Systems, methods, and devices to incentivize inhaler use
US10765817B2 (en) 2014-08-13 2020-09-08 Elwha, Llc Methods, systems, and devices related to delivery of alcohol with an inhaler
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CA3009599A1 (en) 2016-01-06 2017-07-13 Syqe Medical Ltd. Low dose therapeutic treatment
AU2017267979B2 (en) 2016-05-19 2022-03-03 Mannkind Corporation Apparatus, system and method for detecting and monitoring inhalations
WO2018071443A1 (en) * 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
IL270685B (en) 2017-05-22 2022-09-01 Insmed Inc Cleavable derivatives of lipoglycopeptide and their uses

Family Cites Families (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US78212A (en) 1868-05-26 Improvement in machines for molding wood-screws
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US3221733A (en) * 1961-10-02 1965-12-07 Bennett Respiration Products I Pressure breathing therapy unit
US3788310A (en) * 1970-03-25 1974-01-29 Westinghouse Electric Corp Flow control apparatus
GB1392945A (en) * 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
SE408265B (sv) 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
US4086918A (en) * 1976-02-11 1978-05-02 Chesebrough-Pond's Inc. Inhalation device
US4170228A (en) * 1976-11-05 1979-10-09 C. R. Bard, Inc. Variable flow incentive spirometer
US4106503A (en) * 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
US4231375A (en) * 1977-10-20 1980-11-04 Boehringer John R Pulmonary exerciser
GB1598053A (en) 1978-01-31 1981-09-16 Fisons Ltd Pocket inhaler
US4227522A (en) * 1978-09-05 1980-10-14 Syntex Puerto Rico, Inc. Inhalation device
US4274404A (en) * 1979-04-13 1981-06-23 American Safety Flight Systems, Inc. Oxygen supply system controlled by user exhalation
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
US4284083A (en) * 1979-05-29 1981-08-18 Lester Victor E Inhalation incentive device
US4259951A (en) * 1979-07-30 1981-04-07 Chesebrough-Pond's Inc. Dual valve for respiratory device
DE3023648A1 (de) * 1980-06-24 1982-01-21 Jaeger, Erich, 8700 Würzburg Einrichtung zur untersuchung der atemwege auf reizstoff-ueberempfindlichkeit
US4391283A (en) * 1981-03-24 1983-07-05 Whitman Medical Corporation Incentive spirometer
US4484577A (en) 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4442856A (en) * 1981-08-18 1984-04-17 Puritan-Bennett Oxygen regulator and alarm system for an anesthesia machine
US4533137A (en) * 1982-01-19 1985-08-06 Healthscan Inc. Pulmonary training method
US4444202A (en) * 1982-03-31 1984-04-24 Howard Rubin Breathing exerciser
US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
ES286422Y (es) 1982-10-08 1986-09-16 Glaxo Group Limited Dispositivo para administrar medicamentos a pacientes
US4495944A (en) * 1983-02-07 1985-01-29 Trutek Research, Inc. Inhalation therapy apparatus
GB8328808D0 (en) * 1983-10-28 1983-11-30 Riker Laboratories Inc Inhalation responsive dispensers
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4592348A (en) * 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
PT83094B (pt) * 1985-07-30 1993-07-30 Glaxo Group Ltd Dispositivos proprios para a administracao de medicamentos a pacientes
SE453566B (sv) * 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4926852B1 (en) * 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
DE68914932T2 (de) * 1988-10-04 1994-08-11 Univ Johns Hopkins Inhalationsgerät für Aerosolen.
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
US5033655A (en) * 1989-02-15 1991-07-23 Liquid Molding Systems Inc. Dispensing package for fluid products and the like
US4991745A (en) * 1989-04-25 1991-02-12 Liquid Molding Systems, Inc. Dispensing valve with trampoline-like construction
DE69034007T2 (de) * 1989-04-28 2003-05-08 Riker Laboratories Inc., Northridge Inhalationsvorrichtung für Trockenpulver
US4955371A (en) * 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
DE4027391A1 (de) * 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
DE4029183A1 (de) * 1990-09-14 1992-03-19 Dieter Kuhn Durchflussregler
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5042472A (en) * 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
GB9024760D0 (en) * 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
GB9026191D0 (en) 1990-12-01 1991-01-16 Harris Pharma Ltd Breath actuated dispensing device
US5040527A (en) * 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
AU651882B2 (en) * 1991-05-14 1994-08-04 Visiomed Group Limited Aerosol inhalation device
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6055980A (en) * 1991-05-20 2000-05-02 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
DE69230613T2 (de) * 1991-07-02 2000-12-28 Inhale Inc Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
US5167506A (en) * 1991-10-24 1992-12-01 Minnesota Mining And Manufacturing Company Inhalation device training system
US5409144A (en) * 1991-12-06 1995-04-25 Liquid Molding Systems Inc. Dispensing valve for packaging
US5213236A (en) * 1991-12-06 1993-05-25 Liquid Molding Systems, Inc. Dispensing valve for packaging
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5320094A (en) * 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
EP0558879B1 (en) * 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5284133A (en) * 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5333106A (en) * 1992-10-09 1994-07-26 Circadian, Inc. Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers
ATE174804T1 (de) * 1992-10-19 1999-01-15 Dura Pharma Inc Trockenpulverinhalator
DE4239402A1 (de) * 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
EP0681491B1 (en) * 1993-01-29 2000-12-13 Aradigm Corporation Intrapulmonary delivery of hormones
US5364838A (en) 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5873358A (en) * 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US5672581A (en) 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US5558085A (en) * 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
FR2701399B1 (fr) 1993-02-16 1995-03-31 Valois Dispositif portatif de pulvérisation à actionnement déclenché par l'inhalation.
DE69413528T2 (de) 1993-04-06 1999-05-06 Minnesota Mining And Mfg. Co., Saint Paul, Minn. Vorrichtung zum deagglomerieren für trockenpulverinhalatoren
LT3388B (en) 1993-08-17 1995-08-25 Geceviciaus Imone Loro R An advertising stand
EP0714314B1 (en) 1993-08-18 1998-10-14 FISONS plc Inhalator with breath flow regulation
US5655520A (en) * 1993-08-23 1997-08-12 Howe; Harvey James Flexible valve for administering constant flow rates of medicine from a nebulizer
GB9326574D0 (en) 1993-12-31 1994-03-02 King S College London Dry power inhalers
US5479920A (en) * 1994-03-01 1996-01-02 Vortran Medical Technology, Inc. Breath actuated medicinal aerosol delivery apparatus
EP0748213B1 (en) 1994-03-07 2004-04-14 Nektar Therapeutics Methods and compositions for pulmonary delivery of insulin
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5653223A (en) * 1994-09-08 1997-08-05 Pruitt; Michael D. Accurately controlled portable nebulizer
JP3706136B2 (ja) * 1994-09-21 2005-10-12 ネクター セラピューティクス 乾燥粉末薬剤の分散装置及び方法
US5993421A (en) 1994-12-02 1999-11-30 Science Incorporated Medicament dispenser
SE9404439D0 (sv) 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5522380A (en) * 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
ES2145421T3 (es) 1995-01-23 2000-07-01 Direct Haler A S Inhalador.
US5568910A (en) 1995-03-02 1996-10-29 Delmarva Laboratories, Inc. Anesthesia machine
US5513630A (en) * 1995-03-08 1996-05-07 Century; Theodore J. Powder dispenser
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5666945A (en) * 1995-06-07 1997-09-16 Salter Labs Pneumatically-operated gas demand apparatus
US5826571A (en) 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
GB9513218D0 (en) 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5988163A (en) 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5823183A (en) 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5603315A (en) * 1995-08-14 1997-02-18 Reliable Engineering Multiple mode oxygen delivery system
US5865173A (en) * 1995-11-06 1999-02-02 Sunrise Medical Hhg Inc. Bilevel CPAP system with waveform control for both IPAP and EPAP
PT995457E (pt) * 1995-12-07 2004-07-30 Jago Res Ag Bocal para um inalador para a distribuicao reiterada doseadamente de um po farmacologicamente seco
CA2241880A1 (en) * 1996-01-03 1997-07-17 Glaxo Group Limited Inhalation device
US5699789A (en) 1996-03-11 1997-12-23 Hendricks; Mark R. Dry powder inhaler
DE19613185A1 (de) * 1996-04-02 1997-10-09 Pfeiffer Erich Gmbh & Co Kg Dosiereinrichtung für strömungsfähige Medien wie Pulver/Luft-Dispersionen
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
GB2312848B (en) * 1996-04-26 1999-11-17 Bespak Plc Controlled flow inhalers
ATE247948T1 (de) 1996-04-29 2003-09-15 Dura Pharma Inc Verfahren zum inhalieren trockener pulver
AUPN973596A0 (en) * 1996-05-08 1996-05-30 Resmed Limited Control of delivery pressure in cpap treatment or assisted respiration
US5813401A (en) * 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
SE9700422D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Single dose inhaler II
GB2323039B (en) * 1997-03-03 2001-03-14 Bespak Plc Improved inhalation apparatus
GB9705657D0 (en) * 1997-03-19 1997-05-07 Bacon Raymond J Dispenser
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6131571A (en) 1997-04-30 2000-10-17 University Of Florida Ventilation apparatus and anesthesia delivery system
EP0998318B1 (en) * 1997-07-25 2005-04-27 Minnesota Innovative Technologies & Instruments Corporation (MITI) Control device for supplying supplemental respiratory oxygen
DE19734022C2 (de) * 1997-08-06 2000-06-21 Pari Gmbh Inhalationstherapiegerät mit einem Ventil zur Begrenzung des Inspirationsflusses
CA2212430A1 (en) * 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US5855202A (en) * 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US6067984A (en) * 1997-10-14 2000-05-30 Piper; Samuel David Pulmonary modulator apparatus
US6032667A (en) * 1997-10-30 2000-03-07 Instrumentarium Corporation Variable orifice pulse valve
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6076523A (en) * 1998-01-15 2000-06-20 Nellcor Puritan Bennett Oxygen blending in a piston ventilator
RO121834B1 (ro) * 1998-03-16 2008-06-30 Inhale Therapeutic Systems, Inc. Dispozitiv pentru administrarea unui agent activ
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device

Also Published As

Publication number Publication date
CZ20011181A3 (cs) 2001-08-15
IL142215A (en) 2007-07-24
HUP0103805A2 (hu) 2002-02-28
ATE297771T1 (de) 2005-07-15
WO2000021594A2 (en) 2000-04-20
ID28354A (id) 2001-05-17
EP1119384B1 (en) 2005-06-15
HUP0103805A3 (en) 2002-08-28
LT2001057A (en) 2002-02-25
TNSN99188A1 (fr) 2005-11-10
KR100652532B1 (ko) 2006-12-01
EP1119384A2 (en) 2001-08-01
WO2000021594A3 (en) 2000-08-31
UY25731A1 (es) 1999-11-17
LT4902B (lt) 2002-03-25
GT199900174A (es) 2001-03-31
HU225057B1 (en) 2006-05-29
AR020760A1 (es) 2002-05-29
AU1202800A (en) 2000-05-01
LT2001051A (en) 2002-01-25
LV12685B (lv) 2001-10-20
EG22111A (en) 2002-07-31
SK287044B6 (sk) 2009-10-07
EA200100338A1 (ru) 2001-10-22
OA11791A (en) 2005-08-10
LT4907B (lt) 2002-04-25
HK1040645B (en) 2005-12-30
TR200101033T2 (tr) 2001-11-21
IS5904A (is) 2001-03-21
BG105377A (bg) 2001-12-31
DE69925849D1 (de) 2005-07-21
PL193881B1 (pl) 2007-03-30
RO120532B1 (ro) 2006-03-30
HK1040645A1 (en) 2002-06-21
UA73924C2 (en) 2005-10-17
MY129112A (en) 2007-03-30
NZ510853A (en) 2003-08-29
DE69925849T2 (de) 2006-05-18
AP1646A (en) 2006-07-31
MA25865A1 (fr) 2003-10-01
CN101804230B (zh) 2012-10-17
GEP20043259B (en) 2004-06-25
SA99200835B1 (ar) 2006-12-17
CO5060481A1 (es) 2001-07-30
BR9914384A (pt) 2001-06-26
DK1119384T3 (da) 2005-09-19
JP4378057B2 (ja) 2009-12-02
ES2243094T3 (es) 2005-11-16
EE200100212A (et) 2002-06-17
JP2002527151A (ja) 2002-08-27
CA2346791A1 (en) 2000-04-20
AP2001002116A0 (en) 2001-06-30
LV12685A (en) 2001-07-20
PA8484001A1 (es) 2000-09-29
JP2009136688A (ja) 2009-06-25
SK4772001A3 (en) 2001-10-08
NO20011742L (no) 2001-06-06
PL347906A1 (en) 2002-04-22
KR20010075568A (ko) 2001-08-09
US8408200B2 (en) 2013-04-02
YU26101A (sh) 2003-02-28
US20020168322A1 (en) 2002-11-14
EE04608B1 (et) 2006-04-17
HRP20010253A2 (en) 2002-06-30
CA2346791C (en) 2007-12-11
CN1447704A (zh) 2003-10-08
DZ2906A1 (fr) 2004-12-28
PE20001281A1 (es) 2000-11-08
NO20011742D0 (no) 2001-04-06
RS49848B (sr) 2008-08-07
PT1119384E (pt) 2005-09-30
AU754724B2 (en) 2002-11-21
HRP20010253B1 (en) 2006-12-31
ZA200102766B (en) 2001-10-05
CN101804230A (zh) 2010-08-18
EA003405B1 (ru) 2003-04-24

Similar Documents

Publication Publication Date Title
IS5904A (is) Úðagjöf á virkum efnum með mótstöðustýrðu flæði
IS5595A (is) Úðagjöf á virkum efnum
DE69909056D1 (de) Flüssigkeitszerstäuber und düseneinsatz
DE69941495D1 (de) Abgabe von Flüssigkeiten
DE69942754D1 (de) Spritzvorrichtung
DE69927264D1 (de) Aktive fluidfördervorrichtungen mit mikrokanälen
DE69920878D1 (de) Flüssigkeitsbehandlungssystem mit wirbelkammer
DE69929334D1 (de) Flüssigkeitspumpe
ATE308240T1 (de) Flüssige pestizidzusammensetzung
DE69908262D1 (de) Sprühbehälter
ID22421A (id) Nozel aliran laminer
DE69838907D1 (de) Mehrfachstrahldusche mit luftzumischung
DE69821977D1 (de) Flüssige, insektizide aufgiessformulierung
DE69929274D1 (de) Durchflussbegrenzer
DE69915783D1 (de) Spender
DE59810554D1 (de) Flüssigkeitsringpumpe
NO995130D0 (no) Flytende gjödsel
DE69805524D1 (de) Flüssigkeitverteilendes leistungsventil
ATE264616T1 (de) Flüssigformulierung
ITMI20011995A0 (it) Sostanze ad attivita' antinfiammatoria
DE59903934D1 (de) Sprühdose
IT1288418B1 (it) Valvola dosatrice di semplice assemblaggio
IT1314614B1 (it) Flussimetro
NO20005942D0 (no) Flytende konstruksjon
ES1039544Y (es) Pulverizador para liquidos.