IS1586B - Aðferðir við framleiðslu á triazoleefni gegn sveppum og gerlum og myndun þeirra - Google Patents

Aðferðir við framleiðslu á triazoleefni gegn sveppum og gerlum og myndun þeirra

Info

Publication number
IS1586B
IS1586B IS3499A IS3499A IS1586B IS 1586 B IS1586 B IS 1586B IS 3499 A IS3499 A IS 3499A IS 3499 A IS3499 A IS 3499A IS 1586 B IS1586 B IS 1586B
Authority
IS
Iceland
Prior art keywords
germs
formation
production
methods
against fungi
Prior art date
Application number
IS3499A
Other languages
English (en)
Icelandic (is)
Other versions
IS3499A7 (is
Inventor
Roger Peter Dickinson Dr.
Kenneth Richardson Dr.
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10642109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS1586(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of IS3499A7 publication Critical patent/IS3499A7/is
Publication of IS1586B publication Critical patent/IS1586B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IS3499A 1988-08-13 1989-08-10 Aðferðir við framleiðslu á triazoleefni gegn sveppum og gerlum og myndun þeirra IS1586B (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819308A GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents

Publications (2)

Publication Number Publication Date
IS3499A7 IS3499A7 (is) 1990-02-14
IS1586B true IS1586B (is) 1996-03-01

Family

ID=10642109

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3499A IS1586B (is) 1988-08-13 1989-08-10 Aðferðir við framleiðslu á triazoleefni gegn sveppum og gerlum og myndun þeirra

Country Status (38)

Country Link
US (2) US5116844A (en, 2012)
EP (1) EP0357241B1 (en, 2012)
JP (2) JPH0786100B2 (en, 2012)
KR (1) KR930002729B1 (en, 2012)
CN (1) CN1029231C (en, 2012)
AP (1) AP104A (en, 2012)
AR (1) AR246963A1 (en, 2012)
AU (1) AU602638B2 (en, 2012)
BG (1) BG60865B1 (en, 2012)
CA (1) CA1341325C (en, 2012)
CY (1) CY1968A (en, 2012)
CZ (1) CZ284318B6 (en, 2012)
DD (1) DD284010A5 (en, 2012)
DE (1) DE68913105T2 (en, 2012)
DK (1) DK172471B1 (en, 2012)
ES (1) ES2062009T4 (en, 2012)
FI (1) FI96859C (en, 2012)
GB (1) GB8819308D0 (en, 2012)
HU (2) HU205348B (en, 2012)
IE (1) IE61412B1 (en, 2012)
IL (1) IL91231A (en, 2012)
IN (1) IN175438B (en, 2012)
IS (1) IS1586B (en, 2012)
LV (1) LV10714B (en, 2012)
MA (1) MA21610A1 (en, 2012)
MX (1) MX17169A (en, 2012)
MY (1) MY105092A (en, 2012)
NO (1) NO174101C (en, 2012)
NZ (1) NZ230283A (en, 2012)
OA (1) OA09126A (en, 2012)
PE (1) PE1591A1 (en, 2012)
PL (2) PL162953B1 (en, 2012)
PT (1) PT91440B (en, 2012)
RO (1) RO108453B1 (en, 2012)
RU (2) RU1836366C (en, 2012)
SK (1) SK280775B6 (en, 2012)
YU (1) YU47093B (en, 2012)
ZA (1) ZA896151B (en, 2012)

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RU2256655C1 (ru) * 2004-01-27 2005-07-20 Закрытое акционерное общество Фирма "Август" Способ получения 1-(4-хлорфенил)-3-(1,2,4-триазол-1-ил-метил)-4,4-диметилпентан-3-ола
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AR061889A1 (es) 2006-07-13 2008-10-01 Medichem Sa Proceso mejorado para la preparacion de voriconazol
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WO2009137611A2 (en) * 2008-05-06 2009-11-12 Board Of Regents, The University Of Texas System Treatment of pulmonary fungal infection with voriconazole via inhalation
EA019612B1 (ru) * 2009-07-08 2014-04-30 Байер Кропсайенс Аг Замещенные производные фенил(окси/тио)алканолов
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JP5921560B2 (ja) * 2010-10-28 2016-05-24 イノクリン ファーマシューティカルズ，インコーポレイテッド 金属酵素阻害化合物
RU2478106C2 (ru) * 2010-11-25 2013-03-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) СОЕДИНЕНИЯ НА ОСНОВЕ КОМПЛЕКСОВ ГИПЕРРАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ Boltorn H, ОБЛАДАЮЩИЕ АНТИКАНДИДОЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ
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KR20180095108A (ko) 2011-06-19 2018-08-24 비아멧 파마슈티컬즈(엔씨), 인코포레이티드 금속효소 억제제 화합물
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TWI658039B (zh) * 2011-07-08 2019-05-01 維愛美製藥公司 金屬酶抑制劑化合物
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物
KR20150028241A (ko) 2012-05-11 2015-03-13 시플라 리미티드 약학적 조성물
CN102796087B (zh) * 2012-09-04 2015-04-15 西南大学 香豆素三唑醇及其制备方法和用途
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JP6180533B2 (ja) * 2012-10-15 2017-08-16 ファイザー アイルランド ファーマシューティカルズ ボリコナゾールおよびその類似体の調製のための方法
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JPH0786100B2 (ja) 1995-09-20
KR930002729B1 (ko) 1993-04-09
IL91231A (en) 1994-08-26
FI893809L (fi) 1990-02-14
MA21610A1 (fr) 1990-04-01
SK476189A3 (en) 2000-07-11
US5364938A (en) 1994-11-15
HK1000320A1 (en) 1998-02-27
DK394589A (da) 1990-02-14
CA1341325C (en) 2001-12-11
FI893809A0 (fi) 1989-08-11
YU158789A (en) 1991-04-30
AU602638B2 (en) 1990-10-18
CN1029231C (zh) 1995-07-05
US5116844A (en) 1992-05-26
RU2095358C1 (ru) 1997-11-10
YU47093B (sh) 1994-12-28
NO174101C (no) 1994-03-16
JPH02104583A (ja) 1990-04-17
RU1836366C (ru) 1993-08-23
CZ284318B6 (cs) 1998-10-14
ZA896151B (en) 1991-03-27
DK394589D0 (da) 1989-08-11
IE61412B1 (en) 1994-11-02
EP0357241A1 (en) 1990-03-07
IE892582L (en) 1990-02-13
JPH07173154A (ja) 1995-07-11
LV10714A (lv) 1995-06-20
NZ230283A (en) 1991-02-26
AP104A (en) 1990-11-02
IN175438B (en, 2012) 1995-06-17
NO174101B (no) 1993-12-06
MY105092A (en) 1994-08-30
BG60865B1 (bg) 1996-05-31
DE68913105T2 (de) 1994-05-26
CY1968A (en) 1997-09-05
CZ476189A3 (cs) 1998-09-16
PT91440B (pt) 1995-05-04
ES2062009T4 (es) 2006-07-01
HU211511A9 (en) 1995-11-28
IS3499A7 (is) 1990-02-14
HU205348B (en) 1992-04-28
IL91231A0 (en) 1990-03-19
RO108453B1 (ro) 1994-05-31
PT91440A (pt) 1990-03-08
AP8900135A0 (en) 1989-10-31
NO893248D0 (no) 1989-08-11
CN1040795A (zh) 1990-03-28
NO893248L (no) 1990-02-14
DE68913105D1 (de) 1994-03-24
BG89519A (bg) 1993-12-24
PL162953B1 (pl) 1994-01-31
GB8819308D0 (en) 1988-09-14
AU3893089A (en) 1990-03-22
FI96859B (fi) 1996-05-31
MX17169A (es) 1993-08-01
OA09126A (fr) 1991-10-31
PL163756B1 (pl) 1994-04-29
DK172471B1 (da) 1998-09-07
FI96859C (fi) 1996-09-10
LV10714B (en) 1995-12-20
DD284010A5 (de) 1990-10-31
JP2713394B2 (ja) 1998-02-16
SK280775B6 (sk) 2000-07-11
AR246963A1 (es) 1994-10-31
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EP0357241B1 (en) 1994-02-16
KR900003157A (ko) 1990-03-23
HUT52089A (en) 1990-06-28
ES2062009T3 (es) 1994-12-16

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