IN2015DN01855A - - Google Patents

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Publication number
IN2015DN01855A
IN2015DN01855A IN1855DEN2015A IN2015DN01855A IN 2015DN01855 A IN2015DN01855 A IN 2015DN01855A IN 1855DEN2015 A IN1855DEN2015 A IN 1855DEN2015A IN 2015DN01855 A IN2015DN01855 A IN 2015DN01855A
Authority
IN
India
Prior art keywords
subject
micrornas
colorectal
suffering
expression pattern
Prior art date
Application number
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English (en)
Inventor
I Cos Meritxell Gironella
Salvatella Juan Jose Lozano
I Garangou Antoni Castells
Maria Dolores Giraldez
Original Assignee
Hospital Clinic Barcelona
Ct De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas
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Application filed by Hospital Clinic Barcelona, Ct De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas filed Critical Hospital Clinic Barcelona
Publication of IN2015DN01855A publication Critical patent/IN2015DN01855A/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IN1855DEN2015 2011-10-21 2012-10-20 IN2015DN01855A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161550148P 2011-10-21 2011-10-21
PCT/IB2012/003035 WO2013093635A2 (en) 2011-10-21 2012-10-20 Plasma micrornas for the detection of early colorectal cancer

Publications (1)

Publication Number Publication Date
IN2015DN01855A true IN2015DN01855A (es) 2015-07-10

Family

ID=48136439

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1855DEN2015 IN2015DN01855A (es) 2011-10-21 2012-10-20

Country Status (18)

Country Link
US (6) US20130102487A1 (es)
EP (2) EP2768986B1 (es)
JP (2) JP6159727B2 (es)
KR (2) KR101912731B1 (es)
CN (2) CN104145024A (es)
AU (1) AU2012356317B2 (es)
BR (2) BR122015004941B1 (es)
CA (1) CA2852850C (es)
DK (2) DK2944700T3 (es)
ES (2) ES2688693T3 (es)
HU (2) HUE039522T2 (es)
IN (1) IN2015DN01855A (es)
MX (2) MX357119B (es)
NO (1) NO3051026T3 (es)
PL (2) PL2944700T3 (es)
PT (2) PT2768986T (es)
RU (2) RU2611189C2 (es)
WO (1) WO2013093635A2 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120244530A1 (en) 2011-01-26 2012-09-27 Cepheid Methods of detecting lung cancer
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US11913065B2 (en) 2012-09-04 2024-02-27 Guardent Health, Inc. Systems and methods to detect rare mutations and copy number variation
IL305303A (en) 2012-09-04 2023-10-01 Guardant Health Inc Systems and methods for detecting rare mutations and changes in number of copies
US10876152B2 (en) 2012-09-04 2020-12-29 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
CN106062214B (zh) 2013-12-28 2020-06-09 夸登特健康公司 用于检测遗传变异的方法和系统
EP3108012A4 (en) 2014-02-18 2017-10-11 Baylor Research Institute Mir-320e and colorectal cancer
KR102633955B1 (ko) 2014-06-13 2024-02-06 도레이 카부시키가이샤 대장암의 검출 키트 또는 디바이스 및 검출 방법
WO2016034715A2 (fr) * 2014-09-05 2016-03-10 Prestizia Methode de prediction de l'evolution clinique du cancer colorectal
CN104313142B (zh) * 2014-10-16 2016-02-03 上海交通大学医学院附属仁济医院 miRNA-30a作为标记分子在制备诊断试剂中的用途
CN104388541B (zh) * 2014-10-21 2017-07-04 复旦大学附属肿瘤医院 miR‑1914*和miR‑1915的用途
CN104372004B (zh) * 2014-12-04 2018-04-27 广东医学院 一个与心肌梗死易感相关的miR-27a基因单核苷酸多态位点的检测方法及其应用
EP3147370A1 (en) * 2015-09-28 2017-03-29 Rheinische Friedrich-Wilhelms-Universität Bonn Exosomal microrna in serum as an indicator for the activation of brown and beige fat tissue (bat)
CN108603228B (zh) 2015-12-17 2023-09-01 夸登特健康公司 通过分析无细胞dna确定肿瘤基因拷贝数的方法
AU2017313455A1 (en) * 2016-08-18 2019-12-12 Samantha KHOURY Biomarkers of oral, pharyngeal and laryngeal cancers
EP3327135A1 (en) * 2016-11-28 2018-05-30 Advanced Marker Discovery, S.L. In vitro method for identifying colorectal adenomas or colorectal cancer
CN106950370A (zh) * 2017-01-25 2017-07-14 上海市第十人民医院 血液微小核酸大肠癌诊断分子组合
CN107254522A (zh) * 2017-06-09 2017-10-17 中山大学附属第三医院 miR‑664a‑5p的检测试剂在制备肝癌诊断试剂/试剂盒中的应用
CN107236799B (zh) * 2017-06-15 2020-06-09 昆明医科大学第六附属医院 一种肾纤维化miRNA标记物
CN107326092B (zh) * 2017-08-25 2021-07-20 深圳市恩普电子技术有限公司 大肠癌相关的miRNA作为生物标志物的应用及大肠癌检测试剂盒
CN107746886B (zh) * 2017-09-11 2019-10-01 朱伟 一种与结直肠癌辅助诊断相关的血浆miRNA标志物及其应用
WO2019144183A1 (en) * 2018-01-23 2019-08-01 La Trobe University Biomarkers of colorectal cancer
AU2019222462A1 (en) 2018-02-14 2020-09-03 Dermtech, Inc. Novel gene classifiers and uses thereof in non-melanoma skin cancers
CN110205367B (zh) * 2018-02-28 2022-06-21 伽蓝(集团)股份有限公司 一种筛选保护皮肤细胞端粒的活性物的方法
AU2019266226A1 (en) * 2018-05-09 2020-12-03 Dermtech, Inc. Novel gene classifiers and uses thereof in autoimmune diseases
CN114438214B (zh) * 2018-06-27 2023-12-22 深圳华大生命科学研究院 结直肠癌肿瘤标志物及其检测方法与装置
CN109557311B (zh) * 2018-12-13 2022-02-15 中南大学湘雅医院 结直肠癌诊断标志物及结直肠癌的检测产品及其应用
KR102275465B1 (ko) * 2019-01-18 2021-07-09 사회복지법인 삼성생명공익재단 전이성 대장암 치료물질 스크리닝 방법
CN112041463A (zh) * 2019-03-11 2020-12-04 香港中文大学 结肠直肠癌的miRNA标志物
CN110438227A (zh) * 2019-07-29 2019-11-12 广州中昱医学生物科技有限公司 miR-17-92在结直肠癌诊断中的用途
CN112080568A (zh) * 2020-09-27 2020-12-15 扬州大学 一种与湖羊肌肉细胞增殖相关的miRNA标志物及其检测引物和应用
JPWO2023032452A1 (es) * 2021-08-31 2023-03-09
US20230083456A1 (en) * 2021-09-08 2023-03-16 GeneGenieDx Corporation Compositions and methods for diagnosing colorectal cancer
CN113981096A (zh) * 2021-11-30 2022-01-28 无锡市疾病预防控制中心 一种用于诊断结直肠癌的血浆miRNA标志物及其应用
WO2023222927A2 (en) 2022-05-20 2023-11-23 Novigenix Sa Biomarkers for colorectal neoplasia

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB0415277D0 (en) * 2004-07-07 2004-08-11 Colonix Ltd Apparatus and method for sampling mucosal surfaces
US7939255B2 (en) 2006-07-03 2011-05-10 Catholic University Industry Academy Cooperation Foundation Diagnostic methods for colorectal cancer
WO2008055158A2 (en) * 2006-10-30 2008-05-08 University Of South Alabama Microrna as biomarker in cancer
US8252538B2 (en) 2006-11-01 2012-08-28 The Ohio State University MicroRNA expression signature for predicting survival and metastases in hepatocellular carcinoma
MX2010004917A (es) * 2007-10-30 2010-05-20 Veridex Llc Proceso para monitorear el cancer colorrectal.
CN101424640B (zh) * 2007-11-02 2012-07-25 江苏命码生物科技有限公司 血清中微小核糖核酸的检测方法和用于检测的试剂盒、生物芯片及其制作和应用方法
US20090233297A1 (en) * 2008-03-06 2009-09-17 Elizabeth Mambo Microrna markers for recurrence of colorectal cancer
WO2009140670A2 (en) * 2008-05-16 2009-11-19 Veridex, Llc Methods for assessing colorectal cancer and compositions for use therein
WO2010004562A2 (en) 2008-07-09 2010-01-14 Rosetta Genomics Ltd. Methods and compositions for detecting colorectal cancer
EP3181705A1 (en) * 2008-11-12 2017-06-21 Caris Life Sciences Switzerland Holdings GmbH Methods and systems of using exosomes for determining phenotypes
CN102439169B (zh) * 2008-11-13 2014-11-19 复旦大学 用于结肠直肠癌的微rna表达谱分析的组合物和方法
WO2010126355A1 (en) * 2009-04-29 2010-11-04 Academisch Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for counteracting, preventing and/or determining heart failure, or a risk of heart failure
EP2336353A1 (en) * 2009-12-17 2011-06-22 febit holding GmbH miRNA fingerprints in the diagnosis of diseases
US20100317533A1 (en) 2009-06-05 2010-12-16 British Columbia Cancer Agency Branch Biomarkers of cancer metastasis
WO2011012136A1 (en) 2009-07-28 2011-02-03 Exiqon A/S A method for classifying a human cell sample as cancerous
CN101988060A (zh) * 2009-07-30 2011-03-23 江苏命码生物科技有限公司 结直肠癌检测标记物及其检测方法、试剂盒和生物芯片
AR078584A1 (es) * 2009-10-09 2011-11-16 Baylor Res Inst Identificacion de microarn (miarn) en muestras fecales como biomarcador de canceres gastroenterologicos
WO2011076142A1 (en) * 2009-12-24 2011-06-30 Fudan University Compositions and methods for microrna expession profiling in plasma of colorectal cancer
WO2011076147A1 (en) 2009-12-24 2011-06-30 Fudan University Plasma-based micro-rna biomarkers and methods for early detection of colorectal cancer
AU2011205230A1 (en) 2010-01-13 2012-08-02 Caris Life Sciences Switzerland Holdings Gmbh Detection of gastrointestinal disorders
CN102985563A (zh) * 2010-06-23 2013-03-20 香港中文大学 结肠直肠癌的微rna标志物

Also Published As

Publication number Publication date
EP2944700B1 (en) 2017-10-18
BR112014009643A2 (pt) 2017-12-12
CN104651521A (zh) 2015-05-27
CA2852850A1 (en) 2013-06-27
US20150176082A1 (en) 2015-06-25
RU2014120427A (ru) 2015-11-27
AU2012356317B2 (en) 2016-04-07
EP2944700A1 (en) 2015-11-18
HUE035614T2 (en) 2018-05-28
PL2768986T3 (pl) 2018-12-31
ES2662401T3 (es) 2018-04-06
US20130102487A1 (en) 2013-04-25
NO3051026T3 (es) 2018-07-28
PT2944700T (pt) 2018-01-24
US20180355439A1 (en) 2018-12-13
WO2013093635A3 (en) 2013-09-06
WO2013093635A2 (en) 2013-06-27
BR122015004941B1 (pt) 2021-09-28
EP2768986B1 (en) 2018-06-27
JP6159727B2 (ja) 2017-07-05
RU2611189C2 (ru) 2017-02-21
JP2015128442A (ja) 2015-07-16
KR20140097195A (ko) 2014-08-06
JP2014530619A (ja) 2014-11-20
DK2768986T3 (en) 2018-09-10
BR122015004941A2 (pt) 2019-08-20
CN104145024A (zh) 2014-11-12
MX357550B (es) 2018-07-13
PT2768986T (pt) 2018-10-23
JP6203209B2 (ja) 2017-09-27
RU2662975C1 (ru) 2018-07-31
CA2852850C (en) 2020-07-28
PL2944700T3 (pl) 2018-05-30
ES2688693T3 (es) 2018-11-06
KR101912731B1 (ko) 2018-10-29
KR20150036804A (ko) 2015-04-07
US20150087525A1 (en) 2015-03-26
MX2014004810A (es) 2014-11-25
MX357119B (es) 2018-06-27
AU2012356317A1 (en) 2014-05-15
HUE039522T2 (hu) 2019-01-28
KR101900872B1 (ko) 2018-09-20
DK2944700T3 (en) 2018-01-22
US20160289771A1 (en) 2016-10-06
CN104651521B (zh) 2021-08-27
EP2768986A2 (en) 2014-08-27
BR112014009643B1 (pt) 2020-12-15
US20180346996A1 (en) 2018-12-06

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