MX363201B - Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico. - Google Patents

Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico.

Info

Publication number
MX363201B
MX363201B MX2013010127A MX2013010127A MX363201B MX 363201 B MX363201 B MX 363201B MX 2013010127 A MX2013010127 A MX 2013010127A MX 2013010127 A MX2013010127 A MX 2013010127A MX 363201 B MX363201 B MX 363201B
Authority
MX
Mexico
Prior art keywords
determining
pancreatic cancer
array
individual
test sample
Prior art date
Application number
MX2013010127A
Other languages
English (en)
Other versions
MX2013010127A (es
Inventor
Carl Arne Krister Borrebaeck
Lars Bertil Christer Wingren
Original Assignee
Immunovia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunovia Ab filed Critical Immunovia Ab
Publication of MX2013010127A publication Critical patent/MX2013010127A/es
Publication of MX363201B publication Critical patent/MX363201B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5406—IL-4
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5412—IL-6
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5437—IL-13

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a un procedimiento para determinar la presencia de cáncer pancreático en un individuo, que comprende o consiste en las etapas de: (a) proporcionar una muestra a ensayar del individuo y (b) determinar una firma biomarcadora de la muestra de ensayo midiendo la expresión en la muestra de ensayo de uno o más biomarcadores seleccionados del grupo definido en la Tabla III, en el que la expresión en la muestra de ensayo de uno o más biomarcadores seleccionados del grupo definido en la Tabla III es indicativa del cáncer pancreático que padece el individuo. La invención también comprende matrices y kits de partes para su uso en el procedimiento de la invención.
MX2013010127A 2011-03-04 2012-03-05 Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico. MX363201B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1103726.4A GB201103726D0 (en) 2011-03-04 2011-03-04 Method, array and use thereof
PCT/GB2012/050483 WO2012120288A2 (en) 2011-03-04 2012-03-05 Method, array and use thereof

Publications (2)

Publication Number Publication Date
MX2013010127A MX2013010127A (es) 2014-10-15
MX363201B true MX363201B (es) 2019-03-14

Family

ID=43923218

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010127A MX363201B (es) 2011-03-04 2012-03-05 Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico.

Country Status (9)

Country Link
US (4) US9863960B2 (es)
EP (1) EP2681563A2 (es)
JP (1) JP6161542B2 (es)
KR (2) KR20190101489A (es)
CN (2) CN107064518A (es)
CA (1) CA2828338A1 (es)
GB (1) GB201103726D0 (es)
MX (1) MX363201B (es)
WO (1) WO2012120288A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101680896A (zh) 2007-03-27 2010-03-24 伊缪诺维亚公司 检测腺癌的蛋白标志/标记
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
GB201319878D0 (en) * 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof
KR101658164B1 (ko) * 2014-04-28 2016-09-21 서강대학교산학협력단 브롬 동위원소 신호를 이용한 자유 라디칼-개시 펩타이드 시퀀싱 질량분석
KR20150129932A (ko) 2014-05-12 2015-11-23 연세대학교 산학협력단 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트
CN105572276B (zh) * 2014-11-07 2018-12-18 上海市第六人民医院 胰腺癌诊断标记物组合、应用及其测定方法
CN104698170A (zh) * 2015-03-17 2015-06-10 任传利 Il-11作为生物标记物在胰腺癌诊断和预后评价的方法
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
JP5852759B1 (ja) * 2015-04-01 2016-02-03 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
GB201516801D0 (en) 2015-09-22 2015-11-04 Immunovia Ab Method, array and use thereof
JP5970123B1 (ja) * 2015-12-04 2016-08-17 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
JP6392201B2 (ja) * 2015-12-04 2018-09-19 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
KR101594287B1 (ko) 2016-01-13 2016-02-15 연세대학교 산학협력단 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트
DK3411715T3 (da) * 2016-02-05 2020-02-24 Dana Genetic As Fremgangsmåde til diagnostisering og behandling af cancer under anvendelse af antistoffer der binder til c1 inaktivator, c-reaktivt protein og/eller komplement komponent c4
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
DE202017007364U1 (de) 2016-12-16 2021-02-11 The Brigham And Women's Hospital Inc. Anordnung markierter Sensorelemente zum Erfassen unterschiedlicher Proteine, die unterschiedliche Sensorelemente binden
GB201701572D0 (en) 2017-01-31 2017-03-15 Immunovia Ab Methods, arrays and uses thereof
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
KR102594366B1 (ko) 2018-11-07 2023-10-27 시어 인코퍼레이티드 단백질 코로나 분석을 위한 조성물, 방법 및 시스템 및 그것들의 용도
EP3903105A1 (en) * 2019-02-18 2021-11-03 The University Of Liverpool Method of diagnosis
EP4010456A4 (en) 2019-08-05 2023-09-13 Seer, Inc. SYSTEMS AND METHODS FOR SAMPLE PREPARATION, DATA GENERATION AND ANALYSIS OF CORONA PROTEIN
GB202010970D0 (en) * 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
CN113655144A (zh) * 2021-08-09 2021-11-16 大连医科大学附属第一医院 一种基于丙酮酸激酶和α-2-HS-糖蛋白的早期预警重症急性胰腺炎的预测模型

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0039578B1 (en) 1980-05-02 1985-04-10 Edward P. Davis Leg aid device
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5856090A (en) 1994-09-09 1999-01-05 The Scripps Research Institute DNA-methylase linking reaction
GB9703369D0 (en) 1997-02-18 1997-04-09 Lindqvist Bjorn H Process
JP4194080B2 (ja) 2003-02-19 2008-12-10 茂 森村 膵癌検出用マーカー
US20050277137A1 (en) 2003-08-15 2005-12-15 University Of Pittsburgh Diagnostic multimarker serological profiling
US20060106119A1 (en) 2004-01-12 2006-05-18 Chang-Jie Guo Novel integration for CO and H2 recovery in gas to liquid processes
WO2006039671A2 (en) * 2004-09-29 2006-04-13 Central Institute For Experimental Animals Gene markers of tumor metastasis
US8383357B2 (en) 2005-03-16 2013-02-26 OSI Pharmaceuticals, LLC Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors
WO2006110599A2 (en) 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Cacna1e in cancer diagnosis, detection and treatment
JP2008535853A (ja) 2005-04-07 2008-09-04 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド 癌関連遺伝子
JP2007051880A (ja) 2005-08-15 2007-03-01 Tokyo Univ Of Science 膵臓癌の検出方法、膵臓癌の診断キット
WO2007107774A2 (en) * 2006-03-22 2007-09-27 Cartela R & D Ab Integrin alpha-10 subunit as therapeutic target and diagnostic/prognostic marker for cancer
KR100819122B1 (ko) * 2006-09-30 2008-04-04 남명진 췌장암 진단용 키트
RU2473555C2 (ru) 2006-12-19 2013-01-27 ДжинГоу, Инк. Новые способы функционального анализа большого количества экспериментальных данных и групп генов, идентифицированных из указанных данных
CN101680896A (zh) 2007-03-27 2010-03-24 伊缪诺维亚公司 检测腺癌的蛋白标志/标记
GB0723179D0 (en) * 2007-11-27 2008-01-02 Immunovia Ab Diagnostic methods and arrays for use in the same
EP2326734B1 (en) * 2008-09-03 2016-11-09 The Johns Hopkins University Pathways underlying pancreatic tumorigenesis and an hereditary pancreatic cancer gene
WO2010102195A2 (en) 2009-03-06 2010-09-10 The Johns Hopkins University Annexin a11 and associated genes as biomarkers for cancer
CN101880707A (zh) 2009-05-05 2010-11-10 中国人民解放军第二军医大学 microRNA-21在鉴别胰腺癌中的应用
CN101613748A (zh) 2009-06-09 2009-12-30 中国人民解放军第二军医大学 一种检测胰腺癌血清标志物的方法
SG168431A1 (en) 2009-07-23 2011-02-28 Univ Singapore Cancer biomarker and the use thereof
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
GB201319878D0 (en) 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof

Also Published As

Publication number Publication date
EP2681563A2 (en) 2014-01-08
JP2014508298A (ja) 2014-04-03
GB201103726D0 (en) 2011-04-20
US20200088742A1 (en) 2020-03-19
CN103534594A (zh) 2014-01-22
MX2013010127A (es) 2014-10-15
CN107064518A (zh) 2017-08-18
KR20140040118A (ko) 2014-04-02
US20140038844A1 (en) 2014-02-06
JP6161542B2 (ja) 2017-07-12
CA2828338A1 (en) 2012-09-13
WO2012120288A3 (en) 2013-01-10
US20180136231A1 (en) 2018-05-17
KR102014890B1 (ko) 2019-08-27
US20210356478A1 (en) 2021-11-18
WO2012120288A2 (en) 2012-09-13
KR20190101489A (ko) 2019-08-30
US9863960B2 (en) 2018-01-09

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