IN2015DN01737A - - Google Patents

Download PDF

Info

Publication number
IN2015DN01737A
IN2015DN01737A IN1737DEN2015A IN2015DN01737A IN 2015DN01737 A IN2015DN01737 A IN 2015DN01737A IN 1737DEN2015 A IN1737DEN2015 A IN 1737DEN2015A IN 2015DN01737 A IN2015DN01737 A IN 2015DN01737A
Authority
IN
India
Prior art keywords
stem cells
mesenchymal stem
culturing
concentration
viability
Prior art date
Application number
Other languages
English (en)
Inventor
Yoon Sun Yang
Won Il Oh
Sun Jae Kwon
Mi Yeon Lee
Hong Bae Jeon
Original Assignee
Medipost Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medipost Co Ltd filed Critical Medipost Co Ltd
Publication of IN2015DN01737A publication Critical patent/IN2015DN01737A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14Calcium; Ca chelators; Calcitonin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/16Magnesium; Mg chelators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/80Undefined extracts from animals
    • C12N2500/84Undefined extracts from animals from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IN1737DEN2015 2012-09-03 2013-09-02 IN2015DN01737A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020120097193A KR101532556B1 (ko) 2012-09-03 2012-09-03 간엽줄기세포의 배양 방법
PCT/KR2013/007891 WO2014035215A1 (fr) 2012-09-03 2013-09-02 Méthode de culture de cellules souches mésenchymateuses

Publications (1)

Publication Number Publication Date
IN2015DN01737A true IN2015DN01737A (fr) 2015-05-29

Family

ID=50183937

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1737DEN2015 IN2015DN01737A (fr) 2012-09-03 2013-09-02

Country Status (13)

Country Link
US (3) US9580687B2 (fr)
EP (1) EP2893001B1 (fr)
JP (1) JP6478243B2 (fr)
KR (1) KR101532556B1 (fr)
CN (1) CN104781394B (fr)
AU (1) AU2013309642B2 (fr)
CA (1) CA2884000C (fr)
DK (1) DK2893001T3 (fr)
ES (1) ES2755802T3 (fr)
IN (1) IN2015DN01737A (fr)
PL (1) PL2893001T3 (fr)
PT (1) PT2893001T (fr)
WO (1) WO2014035215A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3140417B1 (fr) * 2014-05-09 2021-04-21 Reelabs Private Limited Polymix foetal de cellules souches mésenchymateuses placé dans des conditions hypoxiques en vue du traitement d'affections cliniques
JP6519727B2 (ja) * 2014-09-17 2019-05-29 国立大学法人山口大学 間葉系幹細胞の培養方法、および肝機能障害用治療剤の製造方法
US11000694B2 (en) 2014-10-24 2021-05-11 The Board Of Trustees Of The University Of Illinois Use of lasers for treating and reversing fibrosis
US10287551B2 (en) * 2014-10-29 2019-05-14 R Bio Co., Ltd. Medium composition for culturing stem cells
TWI740812B (zh) * 2015-01-05 2021-10-01 國立陽明大學 用於治療肝臟疾病的間葉幹細胞
JP2018512061A (ja) * 2015-02-20 2018-05-10 ナショナル ヤン−ミン ユニバーシティ 骨関節炎処置のための間葉幹細胞の使用
US20180200301A1 (en) * 2015-05-21 2018-07-19 Shanghai Institutes For Biological Sciences Chinese Academy Of Sciences Low-Oxygen-Treated Mesenchymal Stem Cell and Use Thereof
KR102293012B1 (ko) * 2016-03-31 2021-08-27 샌바이오, 인크. 줄기 세포 배양 및 치료를 위한 배지, 방법, 세포 및 분비 인자
US11753623B2 (en) * 2017-06-05 2023-09-12 The Regents Of The University Of California Compositions for treating retinal diseases and methods for making and using them
CN107384858A (zh) * 2017-08-17 2017-11-24 成都康景生物科技有限公司 一种缺氧耐受型间充质干细胞的制备方法及其应用
CN109666631A (zh) * 2017-10-17 2019-04-23 澳门大学 增强干细胞活性的培养方法、应用以及用于治疗中枢神经疾病的制剂、制备方法及治疗方法
CN109706115B (zh) * 2017-10-26 2023-05-30 中国医科大学 一种小鼠骨髓间充质干细胞细胞系的构建方法
CN108359637B (zh) * 2018-02-14 2021-09-28 浙江生创精准医疗科技有限公司 一种宫血干细胞快速扩增的方法
CN109517786B (zh) * 2018-10-18 2022-06-17 广州元帅生物科技有限公司 一种具有修复功能的多能干细胞制剂及其应用
CA3149572A1 (fr) * 2019-08-30 2021-03-04 Ashlee WATTS Compositions de cellules souches mesenchymateuses exemptes de xenogene et methodes d'utilisation
WO2022004938A1 (fr) * 2020-06-30 2022-01-06 주식회사 미래셀바이오 Procédé de préparation de cellules souches de type mésenchymateuses
CN112147340B (zh) * 2020-09-30 2024-03-08 北京银丰鼎诚生物工程技术有限公司 一种神经干细胞免疫调节功能的检测方法
CN112375733B (zh) * 2020-11-03 2022-09-02 中国人民解放军陆军军医大学第一附属医院 可增进间充质干细胞干细胞性的植物血凝素及其在间充质干细胞扩增培养中的应用
CN113502261B (zh) * 2021-07-16 2023-08-29 上海东方星际干细胞科技有限公司 一种能高效分化成脂的规模化3d低氧间充质干细胞培养体系
CN116218770B (zh) * 2022-12-30 2023-11-24 苏州科为康生物医药科技有限公司 一种间充质干细胞的制备方法和应用
CN117660325B (zh) * 2024-01-31 2024-04-19 苏州科为康生物医药科技有限公司 一种制备脐带血msc的培养基及其方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100494265B1 (ko) 2001-08-14 2005-06-13 메디포스트(주) 관절연골손상 치료용 조성물
WO2003032735A1 (fr) * 2001-10-18 2003-04-24 Lifecell Corporation Remodelage de tissus et d'organes
ES2287447T3 (es) 2002-02-19 2007-12-16 Medipost, Co., Ltd. Metodos de aislamiento y expansion del cultivo de celulas troncales/madre mesenquimatosas a partir de sangre del cordon umbilical, y metodo de diferenciacion de celulas troncales/madre mesenquimatosas derivadas de sangre del cordon umbilical en diversos tejidos mesenquimatosos.
WO2004012503A2 (fr) * 2002-07-30 2004-02-12 Tigenix N.V. Compositions comprenant des cellules precurseurs du muscle et leurs utilisations
WO2005028678A2 (fr) * 2003-06-06 2005-03-31 Wyeth Procedes et materiaux permettant d'identifier des agents modulant le remodelage osseux, et agents ainsi identifies
JP2006055106A (ja) 2004-08-23 2006-03-02 National Institute Of Advanced Industrial & Technology ヒト血清培地を用いるヒト骨髄由来間葉系幹細胞培養法
NZ595786A (en) * 2005-12-29 2013-05-31 Anthrogenesis Corp Placental stem cell populations
US20070178073A1 (en) * 2006-02-01 2007-08-02 Samsung Life Public Welfare Foundation Composition Comprising Separated or Proliferated Cells from Umbilical Cord Blood for Treating Developmental and/or Chronic Lung Disease
EP2630959A1 (fr) * 2007-02-12 2013-08-28 Anthrogenesis Corporation Traitement de maladies inflammatoires au moyen de cellules souches placentaires
US8114668B2 (en) * 2007-05-14 2012-02-14 Cardiac Pacemakers, Inc. Composition for cold storage of stem cells
KR101022032B1 (ko) * 2007-07-20 2011-03-16 동국대학교 산학협력단 중간엽 줄기세포를 이용하여 모유두 조직을 제조하는 방법
GB0715648D0 (en) * 2007-08-10 2007-09-19 Cambridge Silicon Radio Ltd Channel decoding using similarity matching
EP2039758B1 (fr) * 2007-09-21 2010-09-01 Universität Leipzig Support de culture de cellule et procédé de culture de cellules souches et cellules de progéniteur
US20100330047A1 (en) * 2009-06-26 2010-12-30 Life & Light Ltd. Mesenchymal Stem Cells Grown Under Hypoxic Conditions: Compositions, Methods and Uses Therefor
KR101243276B1 (ko) * 2009-10-08 2013-03-13 서울대학교병원 인간 지방 줄기세포의 고활성을 유도하는 방법 및 배지
WO2012018040A1 (fr) * 2010-08-03 2012-02-09 北海道公立大学法人札幌医科大学 Système de culture de cellules de moelle osseuse contenant de l'autosérum, procédé de culture de cellules de moelle osseuse contenant de l'autosérum et procédé de production d'une composition médicinale comprenant des cellules de moelle osseuse de culture, contenant de l'autosérum, en tant que principe actif
US20120052577A1 (en) 2010-08-31 2012-03-01 The Regents Of The University Of California Culture system for stem cell propagation and neural and oligodendrocyte specification

Also Published As

Publication number Publication date
KR101532556B1 (ko) 2015-06-30
US10294456B2 (en) 2019-05-21
EP2893001B1 (fr) 2019-10-30
PL2893001T3 (pl) 2020-03-31
DK2893001T3 (da) 2019-12-02
ES2755802T3 (es) 2020-04-23
KR20140030703A (ko) 2014-03-12
CN104781394B (zh) 2017-12-12
AU2013309642A1 (en) 2015-03-26
US20150284686A1 (en) 2015-10-08
JP2015532596A (ja) 2015-11-12
CA2884000C (fr) 2021-08-24
US11332715B2 (en) 2022-05-17
CN104781394A (zh) 2015-07-15
US20170191036A1 (en) 2017-07-06
WO2014035215A1 (fr) 2014-03-06
AU2013309642B2 (en) 2018-10-25
PT2893001T (pt) 2019-12-09
CA2884000A1 (fr) 2014-03-06
US9580687B2 (en) 2017-02-28
EP2893001A1 (fr) 2015-07-15
JP6478243B2 (ja) 2019-03-06
US20190218517A1 (en) 2019-07-18
EP2893001A4 (fr) 2016-03-09

Similar Documents

Publication Publication Date Title
IN2015DN01737A (fr)
GB201105226D0 (en) Methods
BR112015022770A8 (pt) meio e sistema de cultivo da célula livre de xenógeno, livre de albumina, forma concentrada, métodos de diferenciação de células-tronco pluripotentes humanas, para a produção de mesenquimoangioblastos e sistema definido de cultivo da célula para diferenciação hematoendotelial das células- tronco pluripotentes humanas
JP2018526992A5 (fr)
JP2015507921A5 (fr)
MY160164A (en) Isolating method for umbilical cord blood-derived pluripotent stem cells expressing znf281
NZ627091A (en) Host cells with artificial endosymbionts
WO2012021845A3 (fr) Traitement amélioré utilisant des cellules hématopoïétiques souches et progénitrices
BR112013002811A2 (pt) meios básicos simplificados para cultura celular pluripotente de humano
MX364742B (es) Metodo de cultivo para obtener y mantener una poblacion pura o enriquecida de celulas no diferenciadas neurales y/o celulas progenitoras neurales de mamifero que con propensas a diferenciarse en celulas del linaje oligodendrocitico in vitro.
ZA201206635B (en) Cell culture medium for the growth and differentiation of cells of the hematopoietic lineage
HK1222198A1 (zh) 用於提高幹細胞再生能力的培養基組合物及使用它的幹細胞培養方法
MX366111B (es) Sistema y sustancias para la crioconservacion de celulas viables.
GB2453074A (en) Differentiation of primate pluripotent cells to hepatocyte-lineage cells
MX2013005140A (es) Medios de cultivo de celulas granulados en seco.
WO2011099783A3 (fr) Procédé de production de facteurs de croissance cellulaire à partir de cellules souches dérivées d'adipocytes et de monocytes et applications correspondantes
PH12016502330A1 (en) Method for preparing induced pluripotency stem cells from mesenchymal stem cells by using phlorotannin fraction
WO2012074265A3 (fr) Composition pour la promotion de la stabilité des cellules souches
MX2020014123A (es) Control de niveles de dióxido de carbono y ph en reactores de pequeños volúmenes.
WO2012075462A3 (fr) Méthodes et compositions utilisables en vue du traitement de la dystrophie musculaire progressive
JP2014522668A5 (fr)
WO2012124978A3 (fr) Composition pharmaceutique pour traiter les maladies ischémiques, contenant un milieu conditionné obtenu par culture tridimensionnelle de cellules à titre de principe actif
WO2011112601A3 (fr) Bioréacteur à écoulement continu pour la culture de tissu en trois dimensions stabilisée magnétiquement
WO2014072720A3 (fr) Différenciation cellulaire
WO2012118349A3 (fr) Procédé de différenciation et de prolifération de cellules tueuses naturelles provenant de monocytes cd14 positifs