IN2012DN01983A - - Google Patents
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- Publication number
- IN2012DN01983A IN2012DN01983A IN1983DEN2012A IN2012DN01983A IN 2012DN01983 A IN2012DN01983 A IN 2012DN01983A IN 1983DEN2012 A IN1983DEN2012 A IN 1983DEN2012A IN 2012DN01983 A IN2012DN01983 A IN 2012DN01983A
- Authority
- IN
- India
- Prior art keywords
- pdgfrp
- csf1r
- epha2
- vegfr2
- kit
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23627409P | 2009-08-24 | 2009-08-24 | |
PCT/CN2010/076199 WO2011023081A1 (en) | 2009-08-24 | 2010-08-20 | 5,6-bicyclic heteroaryl-containing urea compounds as kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01983A true IN2012DN01983A (ja) | 2015-07-24 |
Family
ID=43627250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1983DEN2012 IN2012DN01983A (ja) | 2009-08-24 | 2010-08-20 |
Country Status (19)
Country | Link |
---|---|
US (1) | US8648086B2 (ja) |
EP (1) | EP2470533A4 (ja) |
JP (1) | JP2013502444A (ja) |
KR (1) | KR20120089459A (ja) |
CN (1) | CN102066372B (ja) |
AU (1) | AU2010289143A1 (ja) |
BR (1) | BR112012003462A2 (ja) |
CA (1) | CA2769151A1 (ja) |
CO (1) | CO6491087A2 (ja) |
EA (1) | EA201290073A1 (ja) |
EC (1) | ECSP12011691A (ja) |
IL (1) | IL218114A0 (ja) |
IN (1) | IN2012DN01983A (ja) |
MA (1) | MA33559B1 (ja) |
MX (1) | MX2012002317A (ja) |
SG (1) | SG178092A1 (ja) |
TN (1) | TN2012000042A1 (ja) |
WO (1) | WO2011023081A1 (ja) |
ZA (1) | ZA201200890B (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2011119478A (ru) | 2008-10-14 | 2012-11-27 | Нин Си | Соединения и способы применения |
KR20110133048A (ko) | 2009-03-21 | 2011-12-09 | 닝 시 | 아미노 에스테르 유도체, 그의 염 및 이용 방법 |
CN103080109A (zh) * | 2010-09-01 | 2013-05-01 | 苏州爱斯鹏药物研发有限责任公司 | 氘代杂环化合物激酶抑制剂 |
CN103391939B (zh) | 2010-12-03 | 2016-03-09 | Epizyme股份有限公司 | 作为表观遗传酶调节剂的经取代的嘌呤和7-氮杂嘌呤化合物 |
CN102408426B (zh) * | 2011-09-14 | 2013-07-10 | 湖南有色凯铂生物药业有限公司 | 取代的芳香脲类化合物及其作为抗癌药物的应用 |
FR2985257B1 (fr) * | 2011-12-28 | 2014-02-14 | Sanofi Sa | Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique |
CN103420895A (zh) * | 2012-05-18 | 2013-12-04 | 苏州爱斯鹏药物研发有限责任公司 | 一种4-氨基吲哚的制备方法 |
EP2882750A4 (en) | 2012-08-10 | 2016-08-17 | Epizyme Inc | INHIBITORS OF THE PROTEIN METHYLTRANSFERASE DOT1L AND METHOD OF USE THEREOF |
US9597348B2 (en) | 2012-09-06 | 2017-03-21 | Epizyme, Inc. | Method of treating leukemia |
WO2014152566A2 (en) | 2013-03-15 | 2014-09-25 | Epizyme, Inc. | Methods of synthesizing substituted purine compounds |
CN103613580B (zh) * | 2013-09-03 | 2016-02-10 | 遵义医学院 | 用于抗肿瘤药物的3-羟基吲哚-2-酮类化合物或其药学上能够接受的盐 |
CN106279154A (zh) * | 2016-08-02 | 2017-01-04 | 叶芳 | 一种7‑氮杂吲哚‑3‑甲醛的制备方法 |
CN108191874B (zh) * | 2018-01-16 | 2019-11-29 | 成都施贝康生物医药科技有限公司 | 一种C-Kit抑制剂及其应用 |
WO2019228252A1 (zh) * | 2018-06-01 | 2019-12-05 | 杭州阿诺生物医药科技有限公司 | 一种高活性csf1r抑制剂化合物 |
US20210317461A1 (en) | 2018-08-09 | 2021-10-14 | Verseau Therapeutics, Inc. | Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof |
TW202237564A (zh) * | 2020-12-11 | 2022-10-01 | 南韓商日東製藥股份有限公司 | 類鴉片受體的偏置激動劑 |
EP4334298A1 (en) | 2021-06-14 | 2024-03-13 | Scorpion Therapeutics, Inc. | Urea derivatives which can be used to treat cancer |
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DE3928177A1 (de) | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
GB9412719D0 (en) | 1994-06-24 | 1994-08-17 | Erba Carlo Spa | Substituted azaindolylidene compounds and process for their preparation |
GB9604361D0 (en) | 1996-02-29 | 1996-05-01 | Pharmacia Spa | 4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors |
TR199901710T2 (xx) | 1997-01-23 | 1999-09-21 | Smithkline Beecham Corporation | IL-8 resept�r antagonistleri. |
EP1161423B1 (de) * | 1999-03-08 | 2004-11-10 | Bayer HealthCare AG | Thiazolylharnstoff-derivate und ihre verwendung als antivirale mittel |
CO5190696A1 (es) | 1999-06-16 | 2002-08-29 | Smithkline Beecham Corp | Antagonistas de los receptores il-8 |
US6525067B1 (en) * | 1999-11-23 | 2003-02-25 | Pfizer Inc | Substituted heterocyclic derivatives |
US20030158188A1 (en) | 2002-02-20 | 2003-08-21 | Chih-Hung Lee | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US7074805B2 (en) | 2002-02-20 | 2006-07-11 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
JP2005538152A (ja) * | 2002-09-05 | 2005-12-15 | ニューロサーチ、アクティーゼルスカブ | ジアリール誘導体及びこれをクロライドチャネル遮断剤として使用する方法 |
GB0226724D0 (en) | 2002-11-15 | 2002-12-24 | Merck Sharp & Dohme | Therapeutic agents |
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MXPA06011328A (es) | 2004-04-02 | 2006-12-15 | Vertex Pharma | Azaindoles utiles como inhibidotes de roca y otras proteinas cinasas. |
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AR054416A1 (es) | 2004-12-22 | 2007-06-27 | Incyte Corp | Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas. |
RU2402544C2 (ru) | 2005-01-14 | 2010-10-27 | Си Джи Ай ФАРМАСЬЮТИКАЛЗ, ИНК. | 1,3-диарилзамещенные мочевины как модуляторы киназной активности |
JP2008531542A (ja) | 2005-02-24 | 2008-08-14 | ファイザー・プロダクツ・インク | 抗癌剤として有用な二環式複素芳香族誘導体 |
US7777040B2 (en) * | 2005-05-03 | 2010-08-17 | Cgi Pharmaceuticals, Inc. | Certain substituted ureas, as modulators of kinase activity |
BRPI0610066A2 (pt) | 2005-05-17 | 2010-05-25 | Plexxikon Inc | compostos que modulam atividade de c-kit e c-fms e usos para estes |
HUE027370T2 (en) | 2005-06-22 | 2016-10-28 | Plexxikon Inc | Pyrrolo [2,3-b] pyridine derivatives as protein kinase inhibitors |
FR2889526B1 (fr) | 2005-08-04 | 2012-02-17 | Aventis Pharma Sa | 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
JP5072595B2 (ja) * | 2005-08-05 | 2012-11-14 | 中外製薬株式会社 | マルチキナーゼ阻害剤 |
JP2007099642A (ja) * | 2005-09-30 | 2007-04-19 | Tsumura & Co | 含窒素複素環化合物、その製造方法およびそれを用いた医薬組成物 |
KR20080067361A (ko) | 2005-10-28 | 2008-07-18 | 아보트 러보러터리즈 | Trpv1 수용체를 억제하는 인다졸 유도체 |
PT1940844E (pt) * | 2005-10-28 | 2010-01-06 | Scripps Research Inst | Compostos e composições como inibidores de proteína-quinase |
CA2634787C (en) | 2005-12-23 | 2014-10-21 | Smithkline Beecham Corporation | Azaindole inhibitors of aurora kinases |
US20090018156A1 (en) | 2006-02-01 | 2009-01-15 | Jun Tang | Pyrrolo [2,3,B] Pyridine Derivatives Useful As RAF Kinase Inhibitors |
CN101058561B (zh) * | 2006-04-19 | 2011-01-26 | 苏州爱斯鹏药物研发有限责任公司 | 用于抑制蛋白激酶的二苯脲衍生物及其组合物和用途 |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
PE20081581A1 (es) | 2006-12-21 | 2008-11-12 | Plexxikon Inc | COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA |
WO2008079909A1 (en) | 2006-12-21 | 2008-07-03 | Plexxikon, Inc. | Pyrrolo [2,3-b] pyridines as kinase modulators |
WO2008125014A1 (fr) * | 2007-04-13 | 2008-10-23 | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. | Composés d'urée, leurs procédés de préparation et leurs utilisations pharmaceutiques |
-
2010
- 2010-08-20 BR BR112012003462A patent/BR112012003462A2/pt not_active Application Discontinuation
- 2010-08-20 EA EA201290073A patent/EA201290073A1/ru unknown
- 2010-08-20 CA CA2769151A patent/CA2769151A1/en not_active Abandoned
- 2010-08-20 SG SG2012004917A patent/SG178092A1/en unknown
- 2010-08-20 IN IN1983DEN2012 patent/IN2012DN01983A/en unknown
- 2010-08-20 EP EP10811241A patent/EP2470533A4/en not_active Withdrawn
- 2010-08-20 CN CN201080001560.9A patent/CN102066372B/zh not_active Expired - Fee Related
- 2010-08-20 AU AU2010289143A patent/AU2010289143A1/en not_active Abandoned
- 2010-08-20 KR KR1020127006772A patent/KR20120089459A/ko not_active Application Discontinuation
- 2010-08-20 WO PCT/CN2010/076199 patent/WO2011023081A1/en active Application Filing
- 2010-08-20 JP JP2012525875A patent/JP2013502444A/ja active Pending
- 2010-08-20 MX MX2012002317A patent/MX2012002317A/es not_active Application Discontinuation
- 2010-08-20 US US12/922,527 patent/US8648086B2/en not_active Expired - Fee Related
-
2012
- 2012-01-26 CO CO12012075A patent/CO6491087A2/es not_active Application Discontinuation
- 2012-01-26 TN TNP2012000042A patent/TN2012000042A1/en unknown
- 2012-02-06 ZA ZA2012/00890A patent/ZA201200890B/en unknown
- 2012-02-14 IL IL218114A patent/IL218114A0/en unknown
- 2012-02-22 MA MA34647A patent/MA33559B1/fr unknown
- 2012-02-23 EC ECSP12011691 patent/ECSP12011691A/es unknown
Also Published As
Publication number | Publication date |
---|---|
CO6491087A2 (es) | 2012-07-31 |
MA33559B1 (fr) | 2012-09-01 |
ECSP12011691A (es) | 2012-04-30 |
EA201290073A1 (ru) | 2013-01-30 |
TN2012000042A1 (en) | 2013-09-19 |
MX2012002317A (es) | 2012-06-25 |
CN102066372B (zh) | 2014-09-17 |
CN102066372A (zh) | 2011-05-18 |
EP2470533A1 (en) | 2012-07-04 |
IL218114A0 (en) | 2012-04-30 |
BR112012003462A2 (pt) | 2016-02-23 |
KR20120089459A (ko) | 2012-08-10 |
CA2769151A1 (en) | 2011-03-03 |
WO2011023081A1 (en) | 2011-03-03 |
ZA201200890B (en) | 2012-10-31 |
SG178092A1 (en) | 2012-03-29 |
AU2010289143A1 (en) | 2012-02-16 |
US8648086B2 (en) | 2014-02-11 |
US20120122895A1 (en) | 2012-05-17 |
JP2013502444A (ja) | 2013-01-24 |
EP2470533A4 (en) | 2013-01-23 |
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