IN2012DN00338A - - Google Patents

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Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Other languages
English (en)
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (enExample) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (enExample) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (enExample)
EP (1) EP2462157B1 (enExample)
JP (2) JP5791602B2 (enExample)
KR (1) KR101415660B1 (enExample)
CN (2) CN102574911B (enExample)
ES (1) ES2817802T3 (enExample)
IN (1) IN2012DN00338A (enExample)
SG (1) SG177577A1 (enExample)
WO (1) WO2011017514A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3237179B2 (ja) 1992-03-18 2001-12-10 栗田工業株式会社 排超純水中の過酸化水素の除去方法
EP2695889A1 (en) * 2009-12-29 2014-02-12 Dr. Reddy's Laboratories Limited Protein purification by ion exchange
EP2575847B2 (en) 2010-05-25 2022-04-27 F. Hoffmann-La Roche AG Methods of purifying polypeptides
KR101847405B1 (ko) 2010-07-30 2018-04-10 이엠디 밀리포어 코포레이션 크로마토그래피 매질 및 방법
JP6055615B2 (ja) 2011-05-27 2016-12-27 アッヴィ バイオテクノロジー リミテッド Ｄａｃｈｙｐ組成物および方法
BR112013031906A2 (pt) 2011-06-16 2016-12-13 Dsm Ip Assets Bv unidade única de cromatografia de purificação de anticorpo
AU2012282960A1 (en) * 2011-07-08 2014-01-16 Merck Sharp & Dohme Corp. Method for purifying Fc-fusion protein
AU2012283858C1 (en) * 2011-07-20 2020-01-23 Zepteon, Incorporated Polypeptide separation methods
CN103917555A (zh) * 2011-08-01 2014-07-09 艾瓦夏生物制剂公司 人tnf特异性的牛科动物多克隆抗体
WO2013028330A2 (en) * 2011-08-19 2013-02-28 Emd Millipore Corporation Methods of reducing level of one of more impurities in a sample during protein purification
AU2012301751A1 (en) * 2011-09-01 2014-03-13 Human Genome Sciences, Inc. Viral clearance methods
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
CA2854330A1 (en) * 2011-11-02 2013-05-10 Genentech, Inc. Overload and elute chromatography
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN102492040B (zh) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 一种抗her2或/和抗her3抗体蛋白的纯化方法
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
JP6253584B2 (ja) * 2012-08-27 2017-12-27 旭化成メディカル株式会社 温度応答性クロマトグラフィーによる抗体の精製方法
HUE036524T2 (hu) 2012-09-11 2018-07-30 Coherus Biosciences Inc Nagy tisztaságú és kiváló kitermelésû helyesen hajtogatott etanercept
CA2885263C (en) 2012-09-17 2021-11-16 W. R. Grace & Co.-Conn. Chromatography media and devices
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
MX346385B (es) 2013-02-14 2017-03-16 Nanopareil Llc Fieltros hibridos de nanofibras electrohiladas.
KR102272851B1 (ko) * 2013-05-06 2021-07-02 사노피 항체를 정제하기 위한 연속 다단계 공정
CN105848746B (zh) * 2013-09-05 2019-07-09 豪夫迈·罗氏有限公司 用于层析重复利用的方法
SG11201602061YA (en) 2013-09-17 2016-04-28 Kaneka Corp Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom
US9951101B2 (en) 2013-12-12 2018-04-24 Emd Millipore Corporation Protein separations using an acrylamide containing filter
EP3105580B1 (en) * 2014-02-14 2023-10-04 Cytiva Sweden AB Automated multi-step purification system
CN106103465B (zh) * 2014-03-10 2021-01-08 吉瑞工厂 使用预清洗步骤的免疫球蛋白纯化
CN104826617B (zh) * 2014-03-25 2017-06-13 西北大学 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法
CN107847907A (zh) 2014-05-02 2018-03-27 格雷斯公司 官能化载体材料以及制备和使用官能化载体材料的方法
US20170183376A1 (en) * 2014-06-24 2017-06-29 Insight Biopharmaceuticals Ltd. Methods of purifying antibodies
DE102014010353B4 (de) 2014-07-10 2024-09-12 Sartorius Stedim Biotech Gmbh Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien
CN107001410A (zh) * 2014-12-08 2017-08-01 Emd密理博公司 混合床离子交换吸附剂
BR112017026193B1 (pt) 2015-06-05 2021-09-14 W.R. Grace & Co-Conn Adsorventes, método de produção dos adsorventes e uso dos adsorventes
CN109071598A (zh) * 2016-04-05 2018-12-21 美国血液技术公司 从血液中富集免疫球蛋白的方法和装置
CN107964044B (zh) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 从乳样中纯化抗cd20单克隆抗体的方法
CN111902720B (zh) 2018-03-21 2025-02-07 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法
EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
CN113166200B (zh) * 2018-12-21 2024-03-01 上海药明生物技术有限公司 一种提高蛋白a层析法去除聚集体的方法
FR3099066B1 (fr) * 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
TW202128264A (zh) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
CA3156649A1 (en) * 2019-10-04 2021-04-08 Merck Patent Gmbh PROTEIN PURIFICATION AND VIRAL INACTIVATION
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法
CN113845562A (zh) * 2020-06-28 2021-12-28 佛山汉腾生物科技有限公司 目的蛋白纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4490937A (en) * 1981-12-07 1985-01-01 Amcor Ltd. Insect electrocution device
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5256694A (en) * 1984-09-22 1993-10-26 Basf Aktiengesellschaft Diarylacetylenes, their preparation and their use
US5091178A (en) * 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US6054051A (en) * 1996-01-17 2000-04-25 Genentech, Inc. Tangential-flow filtration system
EP1501369B1 (en) * 2002-04-26 2015-06-24 Genentech, Inc. Non-affinity purification of proteins
DK1561756T3 (en) * 2002-09-11 2016-02-15 Chugai Pharmaceutical Co Ltd PROCEDURE FOR CLEANING PROTEIN.
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
CA2581208A1 (en) * 2004-08-30 2006-03-09 Lonza Biologics Plc. Affinity- plus ion exchange- chromatography for purifying antibodies
US20100234577A1 (en) * 2006-06-14 2010-09-16 Smithkline Beecham Corporation Methods for purifying antibodies using ceramic hydroxyapatite
WO2008025748A1 (en) * 2006-08-28 2008-03-06 Ares Trading S.A. Process for the purification of fc-containing proteins
KR20090058532A (ko) 2006-08-28 2009-06-09 아레스 트레이딩 에스.에이. Ｆｃ­융합 단백질을 정제하는 방법
US8168185B2 (en) * 2007-01-17 2012-05-01 Merck Serono Sa Process for the purification of anti CD-25 antibodies
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
WO2009045897A1 (en) * 2007-10-03 2009-04-09 Dyax Corp. Systems and methods for purifying proteins
CN103396480A (zh) * 2008-05-15 2013-11-20 诺沃—诺迪斯克有限公司 抗体纯化方法
NZ592097A (en) * 2008-10-20 2013-01-25 Abbott Lab Viral inactivation during purification of il-12 and il-18 antibodies

Also Published As

Publication number Publication date
KR20120089432A (ko) 2012-08-10
JP5791602B2 (ja) 2015-10-07
CN107188960A (zh) 2017-09-22
US8536316B2 (en) 2013-09-17
JP2015157846A (ja) 2015-09-03
CN102574911A (zh) 2012-07-11
WO2011017514A1 (en) 2011-02-10
JP2013501721A (ja) 2013-01-17
JP6335838B2 (ja) 2018-05-30
EP2462157A1 (en) 2012-06-13
CN102574911B (zh) 2017-06-06
EP2462157A4 (en) 2012-12-26
US20110065901A1 (en) 2011-03-17
SG177577A1 (en) 2012-03-29
EP2462157B1 (en) 2020-06-17
ES2817802T3 (es) 2021-04-08
KR101415660B1 (ko) 2014-07-16

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