JP5791602B2 - 試料中の１つ以上の不純物から標的タンパク質を精製するための方法 - Google Patents

試料中の１つ以上の不純物から標的タンパク質を精製するための方法 Download PDF

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JP5791602B2
JP5791602B2 JP2012523945A JP2012523945A JP5791602B2 JP 5791602 B2 JP5791602 B2 JP 5791602B2 JP 2012523945 A JP2012523945 A JP 2012523945A JP 2012523945 A JP2012523945 A JP 2012523945A JP 5791602 B2 JP5791602 B2 JP 5791602B2
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protein
buffer
region
cation exchange
target protein
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JP2013501721A (ja
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ソイス，ニール
ハバード，ダナ
ジヤン，ユイ
ハルムシク，ジエイムズ
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イー・エム・デイー・ミリポア・コーポレイシヨン
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
JP2012523945A 2009-08-07 2010-08-05 試料中の１つ以上の不純物から標的タンパク質を精製するための方法 Expired - Fee Related JP5791602B2 (ja)

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US27370909P 2009-08-07 2009-08-07
US61/273,709 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

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JP2015093970A Division JP6335838B2 (ja) 2009-08-07 2015-05-01 試料中の１つ以上の不純物から標的タンパク質を精製するための方法

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JP2013501721A JP2013501721A (ja) 2013-01-17
JP5791602B2 true JP5791602B2 (ja) 2015-10-07

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JP2015093970A Expired - Fee Related JP6335838B2 (ja) 2009-08-07 2015-05-01 試料中の１つ以上の不純物から標的タンパク質を精製するための方法

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US (1) US8536316B2 (enExample)
EP (1) EP2462157B1 (enExample)
JP (2) JP5791602B2 (enExample)
KR (1) KR101415660B1 (enExample)
CN (2) CN107188960A (enExample)
ES (1) ES2817802T3 (enExample)
IN (1) IN2012DN00338A (enExample)
SG (1) SG177577A1 (enExample)
WO (1) WO2011017514A1 (enExample)

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JP6612242B2 (ja) * 2014-02-14 2019-11-27 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 自動化された多段階精製システム及び多段階クロマトグラフィー精製方法
PL3116891T3 (pl) 2014-03-10 2020-07-27 Richter Gedeon Nyrt. Oczyszczanie immunoglobuliny z zastosowaniem etapów wstępnego oczyszczania
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JP7163187B2 (ja) * 2016-04-05 2022-10-31 ヘモネティクス・コーポレーション 血液からの免疫グロブリンの濃縮のための方法および装置
CN107964044B (zh) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 从乳样中纯化抗cd20单克隆抗体的方法
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Also Published As

Publication number Publication date
IN2012DN00338A (enExample) 2015-05-22
JP6335838B2 (ja) 2018-05-30
SG177577A1 (en) 2012-03-29
EP2462157A1 (en) 2012-06-13
KR101415660B1 (ko) 2014-07-16
CN102574911A (zh) 2012-07-11
CN102574911B (zh) 2017-06-06
WO2011017514A1 (en) 2011-02-10
US8536316B2 (en) 2013-09-17
CN107188960A (zh) 2017-09-22
ES2817802T3 (es) 2021-04-08
JP2015157846A (ja) 2015-09-03
US20110065901A1 (en) 2011-03-17
KR20120089432A (ko) 2012-08-10
EP2462157A4 (en) 2012-12-26
EP2462157B1 (en) 2020-06-17
JP2013501721A (ja) 2013-01-17

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