IN188411B - - Google Patents

Info

Publication number
IN188411B
IN188411B IN724DE1998A IN188411B IN 188411 B IN188411 B IN 188411B IN 724DE1998 A IN724DE1998 A IN 724DE1998A IN 188411 B IN188411 B IN 188411B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Wook Lee-Korea Jong
Young Lee-Korea Bong
Seop Kim-Korea Chang
Kyu Lee-Korea Seung
Seog Song-Korea Keun
Jin Lee-Korea Song
Jeon Shim-Korea Woo
Soon Hwang-Korea Man
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of IN188411B publication Critical patent/IN188411B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN724DE1998 1997-03-27 1998-03-23 IN188411B (ref)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19970010862 1997-03-27
KR19970010863 1997-03-27

Publications (1)

Publication Number Publication Date
IN188411B true IN188411B (ref) 2002-09-21

Family

ID=26632616

Family Applications (1)

Application Number Title Priority Date Filing Date
IN724DE1998 IN188411B (ref) 1997-03-27 1998-03-23

Country Status (21)

Country Link
US (1) US6352993B1 (ref)
EP (1) EP1015444B1 (ref)
JP (1) JP3176379B2 (ref)
KR (1) KR100278857B1 (ref)
CN (1) CN1118464C (ref)
AR (1) AR012181A1 (ref)
AT (1) ATE241613T1 (ref)
AU (1) AU720385B2 (ref)
BR (1) BR9808070A (ref)
CA (1) CA2284795C (ref)
DE (1) DE69815126T2 (ref)
DK (1) DK1015444T3 (ref)
ES (1) ES2200324T3 (ref)
HU (1) HUP0000851A3 (ref)
IN (1) IN188411B (ref)
PT (1) PT1015444E (ref)
RU (1) RU2203894C2 (ref)
TR (1) TR199902383T2 (ref)
TW (1) TW542831B (ref)
UY (1) UY24938A1 (ref)
WO (1) WO1998043968A1 (ref)

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KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
TW200302728A (en) 2002-02-01 2003-08-16 Novartis Ag Substituted amines as IgE inhibitors
WO2004012659A2 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
AU2004259346A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
JP4800216B2 (ja) * 2003-10-24 2011-10-26 エグゼリクシス， インコーポレイテッド ｐ７０Ｓ６キナーゼモジュレーターおよび使用方法
EP1682133A1 (en) 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
KR101122376B1 (ko) * 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
WO2007042571A1 (en) * 2005-10-14 2007-04-19 Neurosearch A/S Novel pyrimidine-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
JP4946482B2 (ja) 2007-02-08 2012-06-06 船井電機株式会社 緩衝用梱包材及びｔｖ受像機の緩衝用梱包材
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
NZ590688A (en) 2008-08-05 2012-09-28 Daiichi Sankyo Co Ltd imidazo[4,5-b]pyridin-2-one derivatives
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
JP2013542243A (ja) 2010-11-15 2013-11-21 カトリーケ ウニヴェルシテイト ルーヴェン 新規な抗ウイルス性化合物
PL2678332T3 (pl) * 2011-02-25 2016-12-30 Pochodne diaminopirymidyny i sposoby ich wytwarzania
ES2655177T3 (es) * 2012-02-17 2018-02-19 Abbvie Inc. Diaminopirimidinas útiles como inhibidores del virus respiratorio sincitial (VRS) humano
JP6316282B2 (ja) 2012-05-29 2018-04-25 モメンティブ パフォーマンス マテリアルズ ゲーエムベーハー イソシアナートシランの作製
KR20220143164A (ko) 2012-11-21 2022-10-24 피티씨 테라퓨틱스, 인크. 치환된 리버스 피리미딘 ｂｍｉ-1 저해제
WO2014139326A1 (en) 2013-03-13 2014-09-18 Genentech, Inc. Pyrazolo compounds and uses thereof
AR093580A1 (es) * 2013-08-30 2015-06-10 Ptc Therapeutics Inc Inhibidores bmi-1 de pirimidina sustituidos
EP3055301B1 (en) * 2013-10-07 2019-11-20 Kadmon Corporation, LLC (2-(5-isoindolin-2-yl)pyrimidin-4-yl)-amine derivatives as rho kinase inhibitors for treating autoimmune diseases
WO2015076800A1 (en) 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors
EP3209299A4 (en) * 2014-10-22 2018-04-04 The Board of Regents of The University of Texas System Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof
CN105669642B (zh) * 2014-11-19 2020-06-09 江苏天士力帝益药业有限公司 一种盐酸洛氟普啶的制备方法
JP6933322B2 (ja) * 2016-01-04 2021-09-08 メルク セローノ エス．エー． ヒドロキシプロピルチアゾリジンカルボキサミド誘導体のｌ−バリネート及びその塩形態、結晶多形
WO2018184978A1 (de) * 2017-04-05 2018-10-11 Bayer Cropscience Aktiengesellschaft 2-amino-5-oxyalkyl-pyrimidinderivate und deren verwendung zur bekämpfung unerwünschten pflanzenwachstums
CN113164479A (zh) 2018-08-17 2021-07-23 Ptc医疗公司 用于治疗胰腺癌的方法
CN114685369B (zh) * 2022-05-17 2024-02-02 河南省科学院高新技术研究中心 一种利用离子液体制备1-甲基-1,2,3,4-四氢异喹啉的方法

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US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
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US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
DE3901448A1 (de) 1989-01-19 1990-07-26 Basf Ag Emulsionscopolymerisate
EP0388838B1 (de) 1989-03-22 1996-01-10 Ciba-Geigy Ag Schädlingsbekämpfungsmittel
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
CA2015981A1 (en) * 1989-05-10 1990-11-10 Thomas H. Brown Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
CZ400992A3 (en) 1990-11-06 1993-12-15 Pfizer Quinazoline derivatives for enhancing anti-tumor activity
FI934565A7 (fi) 1991-04-17 1993-10-15 Pfizer Pyrimidiinijohdannaisia kasvaimenvastaisen vaikutuksen lisäämiseksi
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
WO1995005363A1 (en) * 1993-08-12 1995-02-23 Astra Aktiebolag Amidine derivatives with nitric oxide synthetase activities
EP0640599B1 (en) 1993-08-26 1998-03-04 Ono Pharmaceutical Co., Ltd. 4-Aminopyrimidine derivatives
RU2153494C2 (ru) 1993-10-12 2000-07-27 Дзе Дюпон Мерк Фармасьютикал Компани 1-n-алкил-n-арилпиримидинамины, способ лечения заболеваний, фармацевтическая композиция
JP2896532B2 (ja) * 1994-08-13 1999-05-31 ユーハン コーポレーション 新規なピリミジン誘導体およびその製造方法
US5990311A (en) * 1996-05-04 1999-11-23 Uhan Corporation Process for preparation of pyrimidine derivatives

Also Published As

Publication number Publication date
TW542831B (en) 2003-07-21
CA2284795C (en) 2004-01-20
RU2203894C2 (ru) 2003-05-10
HUP0000851A1 (hu) 2001-04-28
AU720385B2 (en) 2000-06-01
KR100278857B1 (ko) 2001-01-15
ATE241613T1 (de) 2003-06-15
TR199902383T2 (xx) 2000-06-21
PT1015444E (pt) 2003-10-31
JP2000513014A (ja) 2000-10-03
ES2200324T3 (es) 2004-03-01
EP1015444B1 (en) 2003-05-28
DE69815126D1 (de) 2003-07-03
AU6523998A (en) 1998-10-22
HUP0000851A3 (en) 2002-04-29
HK1026418A1 (en) 2000-12-15
US6352993B1 (en) 2002-03-05
CN1118464C (zh) 2003-08-20
UY24938A1 (es) 2001-01-31
CN1251586A (zh) 2000-04-26
EP1015444A1 (en) 2000-07-05
BR9808070A (pt) 2000-03-08
CA2284795A1 (en) 1998-10-08
DE69815126T2 (de) 2004-04-08
AR012181A1 (es) 2000-09-27
JP3176379B2 (ja) 2001-06-18
WO1998043968A1 (en) 1998-10-08
KR19980080789A (ko) 1998-11-25
DK1015444T3 (da) 2003-08-18

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