IL98542A - History of benzoquinazole preparation and pharmaceutical preparations containing them - Google Patents
History of benzoquinazole preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL98542A IL98542A IL9854291A IL9854291A IL98542A IL 98542 A IL98542 A IL 98542A IL 9854291 A IL9854291 A IL 9854291A IL 9854291 A IL9854291 A IL 9854291A IL 98542 A IL98542 A IL 98542A
- Authority
- IL
- Israel
- Prior art keywords
- group
- methyl
- amino
- compound
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909013615A GB9013615D0 (en) | 1990-06-19 | 1990-06-19 | Pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IL98542A0 IL98542A0 (en) | 1992-07-15 |
IL98542A true IL98542A (en) | 1995-05-26 |
Family
ID=10677828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9854291A IL98542A (en) | 1990-06-19 | 1991-06-18 | History of benzoquinazole preparation and pharmaceutical preparations containing them |
Country Status (26)
Country | Link |
---|---|
US (4) | US6090941A (fr) |
EP (2) | EP1199307B1 (fr) |
JP (1) | JP2966929B2 (fr) |
KR (1) | KR0183042B1 (fr) |
CN (1) | CN1049215C (fr) |
AP (1) | AP218A (fr) |
AT (2) | ATE222243T1 (fr) |
AU (1) | AU639815B2 (fr) |
CA (1) | CA2085589C (fr) |
CS (1) | CS186391A3 (fr) |
DE (2) | DE69133371T2 (fr) |
DK (2) | DK0535034T3 (fr) |
ES (2) | ES2211851T3 (fr) |
FI (1) | FI925778A0 (fr) |
GB (1) | GB9013615D0 (fr) |
HU (2) | HUT62273A (fr) |
IE (1) | IE912073A1 (fr) |
IL (1) | IL98542A (fr) |
MC (1) | MC2290A1 (fr) |
MY (1) | MY107001A (fr) |
NO (1) | NO924929L (fr) |
NZ (1) | NZ238582A (fr) |
PL (1) | PL169927B1 (fr) |
PT (1) | PT98021B (fr) |
WO (1) | WO1991019700A1 (fr) |
ZA (1) | ZA914676B (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6762188B1 (en) | 1990-06-19 | 2004-07-13 | Smithkline Beecham Corporation | Pharmaceutically active benzoquinazoline compounds |
GB9013615D0 (en) | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
GB9223352D0 (en) * | 1992-11-06 | 1992-12-23 | Ici Plc | Tricyclic compounds |
GB9226842D0 (en) * | 1992-12-23 | 1993-02-17 | Wellcome Found | Pharmaceutical compounds |
GB9408936D0 (en) * | 1994-05-05 | 1994-06-22 | Cancer Res Inst | Anti-cancer compounds |
US6531454B1 (en) | 1999-03-16 | 2003-03-11 | The Regents Of The University Of California | Glycosylated polyamines and methods of use therefor |
WO2000055166A1 (fr) | 1999-03-16 | 2000-09-21 | Regents Of The University Of California | Polyamines glycosylees |
MXPA02012068A (es) * | 2000-06-09 | 2004-08-19 | Osi Pharm Inc | Formulaciones liposomales inhibidoras de la timidilato de benzoqunazolina sintasa. |
EP1432711A1 (fr) * | 2001-09-26 | 2004-06-30 | Bayer Corporation | Derives de 1,6-naphthyridine et leur utilisation dans le traitement du diabete et de troubles associes |
CN100434425C (zh) * | 2005-03-09 | 2008-11-19 | 首都师范大学 | 4-喹唑啉酮衍生物及其在抗肿瘤药物中的应用 |
EP1754484A1 (fr) | 2005-08-17 | 2007-02-21 | Dan Stoicescu | Dérives de pyrimidine condenses comme inhibiteurs d`enzymes dependant d`acid folique |
ATE432955T1 (de) | 2005-12-05 | 2009-06-15 | Nitto Denko Corp | Polyglutamat-aminosäure-konjugate und verfahren |
GB0525069D0 (en) * | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
KR101129868B1 (ko) | 2006-10-04 | 2012-04-12 | 화이자 프로덕츠 인코포레이티드 | 칼슘 수용체 길항제로서의 피리도[4,3-d]피리미딘-4(3H)-온 유도체 |
EP1958632A1 (fr) | 2007-02-14 | 2008-08-20 | Dan Stoicescu | Utilisation de dérivés de la pyrimidine condensés pour le traitement de maladies inflammatoires et autoimmunes |
EP2155254B1 (fr) * | 2007-05-09 | 2012-11-28 | Nitto Denko Corporation | Polymères conjugués avec des médicaments à base de platine |
CN101707869A (zh) * | 2007-05-09 | 2010-05-12 | 日东电工株式会社 | 具有多种药物的聚谷氨酸盐结合物和聚谷氨酸盐-氨基酸结合物 |
DK2155255T3 (da) | 2007-05-09 | 2013-09-02 | Nitto Denko Corp | Sammensætninger der omfatter en hydrofob forbindelse og et polyaminosyrekonjugat |
US8517760B2 (en) | 2007-08-20 | 2013-08-27 | Ford Global Technologies, Llc | Cord wrap and power plug receptacle arrangement for inflator |
US8146622B2 (en) | 2007-08-20 | 2012-04-03 | Ford Global Technologies, Llc | Switch and hose-valve connection arrangement for vehicle temporary mobility kit |
US8501242B2 (en) | 2009-05-29 | 2013-08-06 | University Of Florida Research Foundation | Methods and compositions for treating neoplasia |
CN101580501B (zh) * | 2009-06-01 | 2011-03-09 | 南京卡文迪许生物工程技术有限公司 | 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体 |
WO2011078226A1 (fr) * | 2009-12-22 | 2011-06-30 | 協和発酵キリン株式会社 | Composé tricyclique |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UST862021I4 (en) * | 1969-01-27 | 1969-05-27 | Defensive publication | |
ZA72442B (en) * | 1971-02-05 | 1972-10-25 | Apaw Sa | Automatic ice-cream machine |
EP0031237B1 (fr) * | 1979-12-19 | 1984-10-17 | National Research Development Corporation | Dérivés de la quinazoline, procédés pour leur préparation, compositions les contenant et leur utilisation comme agents anticancéreux |
US4814335A (en) * | 1982-12-30 | 1989-03-21 | Biomeasure, Incorporated | Antiviral compounds |
GB8513754D0 (en) * | 1985-05-31 | 1985-07-03 | Jones T R | Anti-cancer quinazoline derivatives |
US4603186A (en) | 1985-10-21 | 1986-07-29 | The Standard Oil Company | Tetrapolymers containing indene |
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
US4818819A (en) * | 1986-10-20 | 1989-04-04 | The Trustees Of Princeton University | Process for the preparation of fused pyridine compounds |
GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
US4857530A (en) * | 1987-11-03 | 1989-08-15 | Warner-Lambert Company | Substituted quinazolinones as anticancer agents |
US4902624A (en) * | 1987-11-23 | 1990-02-20 | Eastman Kodak Company | Temperature cycling cuvette |
GB8727737D0 (en) * | 1987-11-26 | 1987-12-31 | Ici Plc | Antitumour agents |
GB8829296D0 (en) * | 1988-12-15 | 1989-01-25 | Ici Plc | Anti-tumour compounds |
GB9013615D0 (en) * | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
US5405851A (en) * | 1990-06-19 | 1995-04-11 | Burroughs Wellcome Co. | Pharmaceutical compounds |
-
1990
- 1990-06-19 GB GB909013615A patent/GB9013615D0/en active Pending
-
1991
- 1991-06-18 DK DK91910823T patent/DK0535034T3/da active
- 1991-06-18 HU HU924011A patent/HUT62273A/hu unknown
- 1991-06-18 MC MC91@@D patent/MC2290A1/fr unknown
- 1991-06-18 EP EP02075192A patent/EP1199307B1/fr not_active Expired - Lifetime
- 1991-06-18 NZ NZ238582A patent/NZ238582A/en unknown
- 1991-06-18 CN CN91105021A patent/CN1049215C/zh not_active Expired - Fee Related
- 1991-06-18 DE DE69133371T patent/DE69133371T2/de not_active Expired - Fee Related
- 1991-06-18 DE DE69133088T patent/DE69133088T2/de not_active Expired - Fee Related
- 1991-06-18 CA CA002085589A patent/CA2085589C/fr not_active Expired - Lifetime
- 1991-06-18 CS CS911863A patent/CS186391A3/cs unknown
- 1991-06-18 ZA ZA914676A patent/ZA914676B/xx unknown
- 1991-06-18 AP APAP/P/1991/000283A patent/AP218A/en active
- 1991-06-18 MY MYPI91001094A patent/MY107001A/en unknown
- 1991-06-18 ES ES02075192T patent/ES2211851T3/es not_active Expired - Lifetime
- 1991-06-18 KR KR1019920703287A patent/KR0183042B1/ko not_active IP Right Cessation
- 1991-06-18 JP JP3510950A patent/JP2966929B2/ja not_active Expired - Fee Related
- 1991-06-18 EP EP91910823A patent/EP0535034B1/fr not_active Expired - Lifetime
- 1991-06-18 WO PCT/GB1991/000977 patent/WO1991019700A1/fr active IP Right Grant
- 1991-06-18 PL PL91297195A patent/PL169927B1/pl unknown
- 1991-06-18 IL IL9854291A patent/IL98542A/en not_active IP Right Cessation
- 1991-06-18 AT AT91910823T patent/ATE222243T1/de not_active IP Right Cessation
- 1991-06-18 AT AT02075192T patent/ATE260262T1/de not_active IP Right Cessation
- 1991-06-18 PT PT98021A patent/PT98021B/pt not_active IP Right Cessation
- 1991-06-18 DK DK02075192T patent/DK1199307T3/da active
- 1991-06-18 ES ES91910823T patent/ES2178632T3/es not_active Expired - Lifetime
- 1991-06-18 AU AU80943/91A patent/AU639815B2/en not_active Ceased
- 1991-06-18 IE IE207391A patent/IE912073A1/en unknown
-
1992
- 1992-12-18 FI FI925778A patent/FI925778A0/fi not_active Application Discontinuation
- 1992-12-18 NO NO92924929A patent/NO924929L/no unknown
-
1993
- 1993-01-13 US US07/956,018 patent/US6090941A/en not_active Expired - Fee Related
-
1995
- 1995-05-12 HU HU95P/P00133P patent/HU211265A9/hu unknown
- 1995-05-25 US US08/449,959 patent/US5663337A/en not_active Expired - Lifetime
- 1995-05-26 US US08/452,337 patent/US5661155A/en not_active Expired - Lifetime
-
2000
- 2000-06-06 US US09/588,790 patent/US6306865B1/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |