DE69133371D1 - Pharmazeutische wirksame Benzochinazolin Verbindungen - Google Patents
Pharmazeutische wirksame Benzochinazolin VerbindungenInfo
- Publication number
- DE69133371D1 DE69133371D1 DE69133371T DE69133371T DE69133371D1 DE 69133371 D1 DE69133371 D1 DE 69133371D1 DE 69133371 T DE69133371 T DE 69133371T DE 69133371 T DE69133371 T DE 69133371T DE 69133371 D1 DE69133371 D1 DE 69133371D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical active
- benzoquinazoline
- compounds
- benzoquinazoline compounds
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9013615 | 1990-06-19 | ||
GB909013615A GB9013615D0 (en) | 1990-06-19 | 1990-06-19 | Pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69133371D1 true DE69133371D1 (de) | 2004-04-01 |
DE69133371T2 DE69133371T2 (de) | 2005-01-27 |
Family
ID=10677828
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69133371T Expired - Fee Related DE69133371T2 (de) | 1990-06-19 | 1991-06-18 | Pharmazeutische wirksame Benzochinazolin Verbindungen |
DE69133088T Expired - Fee Related DE69133088T2 (de) | 1990-06-19 | 1991-06-18 | Pharmazeutisch wirksame benzochinazolin verbindungen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69133088T Expired - Fee Related DE69133088T2 (de) | 1990-06-19 | 1991-06-18 | Pharmazeutisch wirksame benzochinazolin verbindungen |
Country Status (26)
Country | Link |
---|---|
US (4) | US6090941A (de) |
EP (2) | EP0535034B1 (de) |
JP (1) | JP2966929B2 (de) |
KR (1) | KR0183042B1 (de) |
CN (1) | CN1049215C (de) |
AP (1) | AP218A (de) |
AT (2) | ATE260262T1 (de) |
AU (1) | AU639815B2 (de) |
CA (1) | CA2085589C (de) |
CS (1) | CS186391A3 (de) |
DE (2) | DE69133371T2 (de) |
DK (2) | DK1199307T3 (de) |
ES (2) | ES2211851T3 (de) |
FI (1) | FI925778A0 (de) |
GB (1) | GB9013615D0 (de) |
HU (2) | HUT62273A (de) |
IE (1) | IE912073A1 (de) |
IL (1) | IL98542A (de) |
MC (1) | MC2290A1 (de) |
MY (1) | MY107001A (de) |
NO (1) | NO924929D0 (de) |
NZ (1) | NZ238582A (de) |
PL (1) | PL169927B1 (de) |
PT (1) | PT98021B (de) |
WO (1) | WO1991019700A1 (de) |
ZA (1) | ZA914676B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9013615D0 (en) * | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
US6762188B1 (en) | 1990-06-19 | 2004-07-13 | Smithkline Beecham Corporation | Pharmaceutically active benzoquinazoline compounds |
GB9223352D0 (en) * | 1992-11-06 | 1992-12-23 | Ici Plc | Tricyclic compounds |
GB9226842D0 (en) * | 1992-12-23 | 1993-02-17 | Wellcome Found | Pharmaceutical compounds |
GB9408936D0 (en) * | 1994-05-05 | 1994-06-22 | Cancer Res Inst | Anti-cancer compounds |
US6420344B1 (en) | 1999-03-16 | 2002-07-16 | The Regents Of The University Of California | Glycosylated polyamines |
US6531454B1 (en) | 1999-03-16 | 2003-03-11 | The Regents Of The University Of California | Glycosylated polyamines and methods of use therefor |
CA2412165A1 (en) * | 2000-06-09 | 2001-12-20 | Claudine S. Ashvar | Liposomal benzoquinazoline thymidylate synthase inhibitor formulations |
MXPA04002035A (es) * | 2001-09-26 | 2004-06-07 | Bayer Pharmaceuticals Corp | Derivados de 1, 8-naftiridina y su uso para el tratamiento de la diabetes y trastornos relacionados. |
CN100434425C (zh) * | 2005-03-09 | 2008-11-19 | 首都师范大学 | 4-喹唑啉酮衍生物及其在抗肿瘤药物中的应用 |
EP1754484A1 (de) * | 2005-08-17 | 2007-02-21 | Dan Stoicescu | Kondensierte Pyrimidinderivative als Inhibitoren der Folsäure-abhängiger Enzyme |
EP2206736B1 (de) | 2005-12-05 | 2012-02-08 | Nitto Denko Corporation | Polyglutamat-Aminosäure-Konjugate und Verfahren |
GB0525069D0 (en) * | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
JP2010505811A (ja) | 2006-10-04 | 2010-02-25 | ファイザー・プロダクツ・インク | カルシウム受容体アンタゴニストとしてのピリド[4,3−d]ピリミジン−4(3H)−オン誘導体 |
EP1958632A1 (de) | 2007-02-14 | 2008-08-20 | Dan Stoicescu | Kondensierte Pyrimidinderivaten zur Behandlung von Entzündungserkrankungen und Autoimmunerkrankungen |
CN101730549B (zh) * | 2007-05-09 | 2015-12-09 | 日东电工株式会社 | 与铂类药物结合的聚合物 |
JP2010526917A (ja) * | 2007-05-09 | 2010-08-05 | 日東電工株式会社 | 複数種の薬物を有するポリグルタミン酸塩複合体及びポリグルタミン酸塩−アミノ酸複合体 |
EP2155255B1 (de) | 2007-05-09 | 2013-08-14 | Nitto Denko Corporation | Zusammensetzungen, die eine hydrophobe Verbindung und ein Polyaminosäurekonjugat beinhalten |
US8146622B2 (en) | 2007-08-20 | 2012-04-03 | Ford Global Technologies, Llc | Switch and hose-valve connection arrangement for vehicle temporary mobility kit |
US8517760B2 (en) | 2007-08-20 | 2013-08-27 | Ford Global Technologies, Llc | Cord wrap and power plug receptacle arrangement for inflator |
US8501242B2 (en) | 2009-05-29 | 2013-08-06 | University Of Florida Research Foundation | Methods and compositions for treating neoplasia |
CN101580501B (zh) * | 2009-06-01 | 2011-03-09 | 南京卡文迪许生物工程技术有限公司 | 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体 |
WO2011078226A1 (ja) * | 2009-12-22 | 2011-06-30 | 協和発酵キリン株式会社 | 三環系化合物 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UST862021I4 (en) * | 1969-01-27 | 1969-05-27 | Defensive publication | |
DE2202847A1 (de) * | 1971-02-05 | 1972-08-17 | Apaw Sa | Speiseeismaschine,insbesondere fuer Familiengebrauch,Kleinbetriebe od.dgl. |
EP0031237B1 (de) * | 1979-12-19 | 1984-10-17 | National Research Development Corporation | Chinazolinderivate, Verfahren zu ihrer Herstellung, sie enthaltende Zusammensetzungen und ihre Verwendung als Anti-Krebs-Mittel |
US4814335A (en) * | 1982-12-30 | 1989-03-21 | Biomeasure, Incorporated | Antiviral compounds |
GB8513754D0 (en) * | 1985-05-31 | 1985-07-03 | Jones T R | Anti-cancer quinazoline derivatives |
US4603186A (en) | 1985-10-21 | 1986-07-29 | The Standard Oil Company | Tetrapolymers containing indene |
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
US4818819A (en) * | 1986-10-20 | 1989-04-04 | The Trustees Of Princeton University | Process for the preparation of fused pyridine compounds |
GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
US4857530A (en) * | 1987-11-03 | 1989-08-15 | Warner-Lambert Company | Substituted quinazolinones as anticancer agents |
US4902624A (en) * | 1987-11-23 | 1990-02-20 | Eastman Kodak Company | Temperature cycling cuvette |
GB8727737D0 (en) * | 1987-11-26 | 1987-12-31 | Ici Plc | Antitumour agents |
GB8829296D0 (en) * | 1988-12-15 | 1989-01-25 | Ici Plc | Anti-tumour compounds |
GB9013615D0 (en) * | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
US5405851A (en) * | 1990-06-19 | 1995-04-11 | Burroughs Wellcome Co. | Pharmaceutical compounds |
-
1990
- 1990-06-19 GB GB909013615A patent/GB9013615D0/en active Pending
-
1991
- 1991-06-18 PL PL91297195A patent/PL169927B1/pl unknown
- 1991-06-18 KR KR1019920703287A patent/KR0183042B1/ko not_active IP Right Cessation
- 1991-06-18 MC MC91@@D patent/MC2290A1/xx unknown
- 1991-06-18 JP JP3510950A patent/JP2966929B2/ja not_active Expired - Fee Related
- 1991-06-18 EP EP91910823A patent/EP0535034B1/de not_active Expired - Lifetime
- 1991-06-18 AT AT02075192T patent/ATE260262T1/de not_active IP Right Cessation
- 1991-06-18 CS CS911863A patent/CS186391A3/cs unknown
- 1991-06-18 IE IE207391A patent/IE912073A1/en unknown
- 1991-06-18 EP EP02075192A patent/EP1199307B1/de not_active Expired - Lifetime
- 1991-06-18 DK DK02075192T patent/DK1199307T3/da active
- 1991-06-18 IL IL9854291A patent/IL98542A/en not_active IP Right Cessation
- 1991-06-18 AU AU80943/91A patent/AU639815B2/en not_active Ceased
- 1991-06-18 HU HU924011A patent/HUT62273A/hu unknown
- 1991-06-18 PT PT98021A patent/PT98021B/pt not_active IP Right Cessation
- 1991-06-18 ZA ZA914676A patent/ZA914676B/xx unknown
- 1991-06-18 NZ NZ238582A patent/NZ238582A/en unknown
- 1991-06-18 ES ES02075192T patent/ES2211851T3/es not_active Expired - Lifetime
- 1991-06-18 DK DK91910823T patent/DK0535034T3/da active
- 1991-06-18 DE DE69133371T patent/DE69133371T2/de not_active Expired - Fee Related
- 1991-06-18 ES ES91910823T patent/ES2178632T3/es not_active Expired - Lifetime
- 1991-06-18 DE DE69133088T patent/DE69133088T2/de not_active Expired - Fee Related
- 1991-06-18 CA CA002085589A patent/CA2085589C/en not_active Expired - Lifetime
- 1991-06-18 MY MYPI91001094A patent/MY107001A/en unknown
- 1991-06-18 CN CN91105021A patent/CN1049215C/zh not_active Expired - Fee Related
- 1991-06-18 AT AT91910823T patent/ATE222243T1/de not_active IP Right Cessation
- 1991-06-18 AP APAP/P/1991/000283A patent/AP218A/en active
- 1991-06-18 WO PCT/GB1991/000977 patent/WO1991019700A1/en active IP Right Grant
-
1992
- 1992-12-18 NO NO924929A patent/NO924929D0/no unknown
- 1992-12-18 FI FI925778A patent/FI925778A0/fi not_active Application Discontinuation
-
1993
- 1993-01-13 US US07/956,018 patent/US6090941A/en not_active Expired - Fee Related
-
1995
- 1995-05-12 HU HU95P/P00133P patent/HU211265A9/hu unknown
- 1995-05-25 US US08/449,959 patent/US5663337A/en not_active Expired - Lifetime
- 1995-05-26 US US08/452,337 patent/US5661155A/en not_active Expired - Lifetime
-
2000
- 2000-06-06 US US09/588,790 patent/US6306865B1/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |