DE69121734D1 - Spiroisoindole Verbindungen - Google Patents

Spiroisoindole Verbindungen

Info

Publication number
DE69121734D1
DE69121734D1 DE69121734T DE69121734T DE69121734D1 DE 69121734 D1 DE69121734 D1 DE 69121734D1 DE 69121734 T DE69121734 T DE 69121734T DE 69121734 T DE69121734 T DE 69121734T DE 69121734 D1 DE69121734 D1 DE 69121734D1
Authority
DE
Germany
Prior art keywords
spiroisoindole
compounds
spiroisoindole compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69121734T
Other languages
English (en)
Inventor
Thomas Michael Bare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Zeneca Inc
Original Assignee
Zeneca Ltd
Zeneca Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Zeneca Inc filed Critical Zeneca Ltd
Application granted granted Critical
Publication of DE69121734D1 publication Critical patent/DE69121734D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
DE69121734T 1990-02-08 1991-02-05 Spiroisoindole Verbindungen Expired - Lifetime DE69121734D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909002834A GB9002834D0 (en) 1990-02-08 1990-02-08 Compounds

Publications (1)

Publication Number Publication Date
DE69121734D1 true DE69121734D1 (de) 1996-10-10

Family

ID=10670634

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69121734T Expired - Lifetime DE69121734D1 (de) 1990-02-08 1991-02-05 Spiroisoindole Verbindungen

Country Status (6)

Country Link
US (1) US5098925A (de)
EP (1) EP0441598B1 (de)
JP (1) JP2956788B2 (de)
CA (1) CA2035966A1 (de)
DE (1) DE69121734D1 (de)
GB (1) GB9002834D0 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5862883A (en) * 1995-03-10 1999-01-26 Jennifer Carriere Tree stand
CN109020994A (zh) * 2017-06-12 2018-12-18 华东师范大学 一种苯并噻吩螺氧化吲哚衍生物及其合成方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3308134A (en) * 1965-10-22 1967-03-07 Mcneilab Inc Spiro(indan-2, 3'-indoline)-1, 2'-diones
DE2834607A1 (de) * 1978-08-07 1980-02-28 Basf Ag Verfahren zur herstellung von indoleninen
NZ225634A (en) * 1987-08-10 1991-03-26 Merck & Co Inc 10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine derivatives and pharmaceutical compositions
GB8719199D0 (en) * 1987-08-13 1987-09-23 Merck Sharp & Dohme Chemical compounds
GB8727989D0 (en) * 1987-11-30 1988-01-06 Merck Sharp & Dohme Therapeutic agents
WO1990015060A1 (en) * 1989-06-01 1990-12-13 Pfizer Inc. 4,5,6,11-TETRAHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES AND 6,11-DIHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES

Also Published As

Publication number Publication date
JPH0517441A (ja) 1993-01-26
JP2956788B2 (ja) 1999-10-04
EP0441598A2 (de) 1991-08-14
EP0441598A3 (en) 1992-03-11
CA2035966A1 (en) 1991-08-09
US5098925A (en) 1992-03-24
EP0441598B1 (de) 1996-09-04
GB9002834D0 (en) 1990-04-04

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Legal Events

Date Code Title Description
8332 No legal effect for de