DK1199307T3 - Farmaceutisk aktive benzoquinazolinforbindelser - Google Patents

Farmaceutisk aktive benzoquinazolinforbindelser

Info

Publication number
DK1199307T3
DK1199307T3 DK02075192T DK02075192T DK1199307T3 DK 1199307 T3 DK1199307 T3 DK 1199307T3 DK 02075192 T DK02075192 T DK 02075192T DK 02075192 T DK02075192 T DK 02075192T DK 1199307 T3 DK1199307 T3 DK 1199307T3
Authority
DK
Denmark
Prior art keywords
pharmaceutically active
benzoquinazoline
compounds
benzoquinazoline compounds
pharmaceutically
Prior art date
Application number
DK02075192T
Other languages
English (en)
Inventor
Scott Howard Dickerson
Robert Ferone
William Pendergast
Julius Vass Johnson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of DK1199307T3 publication Critical patent/DK1199307T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
DK02075192T 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser DK1199307T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909013615A GB9013615D0 (en) 1990-06-19 1990-06-19 Pharmaceutical compounds
EP91910823A EP0535034B1 (en) 1990-06-19 1991-06-18 Pharmaceutically active benzoquinazoline compounds

Publications (1)

Publication Number Publication Date
DK1199307T3 true DK1199307T3 (da) 2004-06-14

Family

ID=10677828

Family Applications (2)

Application Number Title Priority Date Filing Date
DK91910823T DK0535034T3 (da) 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser
DK02075192T DK1199307T3 (da) 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK91910823T DK0535034T3 (da) 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser

Country Status (26)

Country Link
US (4) US6090941A (da)
EP (2) EP1199307B1 (da)
JP (1) JP2966929B2 (da)
KR (1) KR0183042B1 (da)
CN (1) CN1049215C (da)
AP (1) AP218A (da)
AT (2) ATE260262T1 (da)
AU (1) AU639815B2 (da)
CA (1) CA2085589C (da)
CS (1) CS186391A3 (da)
DE (2) DE69133371T2 (da)
DK (2) DK0535034T3 (da)
ES (2) ES2211851T3 (da)
FI (1) FI925778A0 (da)
GB (1) GB9013615D0 (da)
HU (2) HUT62273A (da)
IE (1) IE912073A1 (da)
IL (1) IL98542A (da)
MC (1) MC2290A1 (da)
MY (1) MY107001A (da)
NO (1) NO924929D0 (da)
NZ (1) NZ238582A (da)
PL (1) PL169927B1 (da)
PT (1) PT98021B (da)
WO (1) WO1991019700A1 (da)
ZA (1) ZA914676B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US6762188B1 (en) 1990-06-19 2004-07-13 Smithkline Beecham Corporation Pharmaceutically active benzoquinazoline compounds
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9226842D0 (en) * 1992-12-23 1993-02-17 Wellcome Found Pharmaceutical compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
US6531454B1 (en) 1999-03-16 2003-03-11 The Regents Of The University Of California Glycosylated polyamines and methods of use therefor
WO2000055166A1 (en) 1999-03-16 2000-09-21 Regents Of The University Of California Glycosylated polyamines
PL360470A1 (en) * 2000-06-09 2004-09-06 Osi Pharmaceuticals, Inc. Liposomal benzoquinazoline thymidylate synthase inhibitor formulations
CA2463039A1 (en) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation 1,6-naphthyridine derivatives as antidiabetics
CN100434425C (zh) * 2005-03-09 2008-11-19 首都师范大学 4-喹唑啉酮衍生物及其在抗肿瘤药物中的应用
EP1754484A1 (en) 2005-08-17 2007-02-21 Dan Stoicescu Condensed pyrimidine derivatives as inhibitors of foic acid-dependent enzymes
RU2472812C2 (ru) 2005-12-05 2013-01-20 НИТТО ДЕНКО КОРПОРЭЙШН (Джэпэн/Джэпэн) Конъюгаты полиглутамат-аминокислота и способы
GB0525069D0 (en) * 2005-12-08 2006-01-18 Novartis Ag Organic compounds
KR101129868B1 (ko) 2006-10-04 2012-04-12 화이자 프로덕츠 인코포레이티드 칼슘 수용체 길항제로서의 피리도［4,3-ｄ］피리미딘-4(3Ｈ)-온 유도체
EP1958632A1 (en) 2007-02-14 2008-08-20 Dan Stoicescu Use of condensed pyrimidine derivatives for the treatment of autoimmune and inflammatory diseases
JP2010526917A (ja) * 2007-05-09 2010-08-05 日東電工株式会社 複数種の薬物を有するポリグルタミン酸塩複合体及びポリグルタミン酸塩−アミノ酸複合体
WO2008141107A2 (en) 2007-05-09 2008-11-20 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
JP2010528122A (ja) * 2007-05-09 2010-08-19 日東電工株式会社 白金薬剤と結合されたポリマー
US8146622B2 (en) 2007-08-20 2012-04-03 Ford Global Technologies, Llc Switch and hose-valve connection arrangement for vehicle temporary mobility kit
US8517760B2 (en) 2007-08-20 2013-08-27 Ford Global Technologies, Llc Cord wrap and power plug receptacle arrangement for inflator
WO2010138955A2 (en) 2009-05-29 2010-12-02 University Of Florida Research Foundation, Inc. Methods and compositions for treating neoplasia
CN101580501B (zh) 2009-06-01 2011-03-09 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体
WO2011078226A1 (ja) * 2009-12-22 2011-06-30 協和発酵キリン株式会社 三環系化合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UST862021I4 (en) * 1969-01-27 1969-05-27 Defensive publication
ZA72442B (en) * 1971-02-05 1972-10-25 Apaw Sa Automatic ice-cream machine
GB2065653B (en) * 1979-12-19 1983-03-09 Nat Res Dev Anti-cancer quinazoline derivatives
US4814335A (en) * 1982-12-30 1989-03-21 Biomeasure, Incorporated Antiviral compounds
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US4603186A (en) 1985-10-21 1986-07-29 The Standard Oil Company Tetrapolymers containing indene
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
US4902624A (en) * 1987-11-23 1990-02-20 Eastman Kodak Company Temperature cycling cuvette
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US5405851A (en) * 1990-06-19 1995-04-11 Burroughs Wellcome Co. Pharmaceutical compounds

Also Published As

Publication number Publication date
PL169927B1 (pl) 1996-09-30
CN1049215C (zh) 2000-02-09
ATE222243T1 (de) 2002-08-15
EP0535034A1 (en) 1993-04-07
HU211265A9 (en) 1995-11-28
EP0535034B1 (en) 2002-08-14
GB9013615D0 (en) 1990-08-08
CS186391A3 (en) 1992-04-15
DE69133088D1 (de) 2002-09-19
US5661155A (en) 1997-08-26
AP218A (en) 1992-09-27
FI925778A (fi) 1992-12-18
IL98542A (en) 1995-05-26
NO924929L (no) 1992-12-18
KR0183042B1 (ko) 1999-05-01
KR930701415A (ko) 1993-06-11
MC2290A1 (fr) 1993-07-14
DE69133371T2 (de) 2005-01-27
JP2966929B2 (ja) 1999-10-25
US6306865B1 (en) 2001-10-23
HUT62273A (en) 1993-04-28
AU8094391A (en) 1992-01-07
DE69133371D1 (de) 2004-04-01
PT98021B (pt) 1998-11-30
EP1199307B1 (en) 2004-02-25
AU639815B2 (en) 1993-08-05
US5663337A (en) 1997-09-02
US6090941A (en) 2000-07-18
CA2085589C (en) 2001-12-18
CA2085589A1 (en) 1991-12-20
ES2211851T3 (es) 2004-07-16
PT98021A (pt) 1992-04-30
NZ238582A (en) 1993-12-23
JPH05507704A (ja) 1993-11-04
HU9204011D0 (en) 1993-03-29
CN1058208A (zh) 1992-01-29
FI925778A0 (fi) 1992-12-18
DE69133088T2 (de) 2003-03-20
IL98542A0 (en) 1992-07-15
EP1199307A1 (en) 2002-04-24
NO924929D0 (no) 1992-12-18
AP9100283A0 (en) 1991-07-31
ATE260262T1 (de) 2004-03-15
IE912073A1 (en) 1992-01-01
DK0535034T3 (da) 2002-12-09
ES2178632T3 (es) 2003-01-01
WO1991019700A1 (en) 1991-12-26
MY107001A (en) 1995-08-30
ZA914676B (en) 1993-02-24

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