IL97289A - History 8) Hetero (Aryl-H3, H6, 1, 4 a5, 8 - Tetraazacinaphthiline - H) 5 43 (- Discussion, pharmaceutical preparations containing them, and processes for their preparation - Google Patents

History 8) Hetero (Aryl-H3, H6, 1, 4 a5, 8 - Tetraazacinaphthiline - H) 5 43 (- Discussion, pharmaceutical preparations containing them, and processes for their preparation

Info

Publication number
IL97289A
IL97289A IL9728991A IL9728991A IL97289A IL 97289 A IL97289 A IL 97289A IL 9728991 A IL9728991 A IL 9728991A IL 9728991 A IL9728991 A IL 9728991A IL 97289 A IL97289 A IL 97289A
Authority
IL
Israel
Prior art keywords
alkyl
compound
hydrogen
carbon atoms
formula
Prior art date
Application number
IL9728991A
Other languages
English (en)
Hebrew (he)
Other versions
IL97289A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL97289A0 publication Critical patent/IL97289A0/xx
Publication of IL97289A publication Critical patent/IL97289A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
IL9728991A 1990-02-21 1991-02-20 History 8) Hetero (Aryl-H3, H6, 1, 4 a5, 8 - Tetraazacinaphthiline - H) 5 43 (- Discussion, pharmaceutical preparations containing them, and processes for their preparation IL97289A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/482,568 US5013737A (en) 1988-02-22 1990-02-21 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones

Publications (2)

Publication Number Publication Date
IL97289A0 IL97289A0 (en) 1992-05-25
IL97289A true IL97289A (en) 1995-06-29

Family

ID=23916572

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9728991A IL97289A (en) 1990-02-21 1991-02-20 History 8) Hetero (Aryl-H3, H6, 1, 4 a5, 8 - Tetraazacinaphthiline - H) 5 43 (- Discussion, pharmaceutical preparations containing them, and processes for their preparation

Country Status (24)

Country Link
US (1) US5013737A (hu)
EP (1) EP0443312B1 (hu)
JP (1) JP3046851B2 (hu)
KR (1) KR0183395B1 (hu)
AT (1) ATE152723T1 (hu)
AU (1) AU640202B2 (hu)
CA (1) CA2036589A1 (hu)
CZ (1) CZ285584B6 (hu)
DE (1) DE69125962T2 (hu)
DK (1) DK0443312T3 (hu)
ES (1) ES2102371T3 (hu)
FI (1) FI93963C (hu)
GR (1) GR3024063T3 (hu)
HU (1) HUT60500A (hu)
IE (1) IE910575A1 (hu)
IL (1) IL97289A (hu)
NO (1) NO177749C (hu)
NZ (1) NZ237123A (hu)
PH (1) PH27464A (hu)
PL (1) PL166100B1 (hu)
PT (1) PT96805B (hu)
SG (1) SG47638A1 (hu)
SK (1) SK279997B6 (hu)
ZA (1) ZA911260B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1129091B1 (en) * 1998-11-12 2002-10-02 Neurocrine Biosciences, Inc. Crf receptor antagonists and methods relating thereto
DK1129096T3 (da) * 1998-11-12 2003-09-15 Neurocrine Biosciences Inc CRF-receptorantagonister og fremgangsmåder, der er relateret dertil
BRPI0708813A2 (pt) * 2006-03-17 2011-05-24 Wyeth Corp composto; composição; método de tratamento, inibição do crescimento ou erradicaçõ de neoplasias em um mamìfero necessitado; método de tratamento dse cáncer em um mamìfero necessitado; e mistura
US20070219183A1 (en) * 2006-03-17 2007-09-20 Wyeth Dihydropyrazolo[1,5-A]pyrimidine and dihydroimidazo[1,5-A]pyrimidine derivatives and methods of use thereof
KR200480580Y1 (ko) * 2015-09-30 2016-06-13 김영직 어린이용 우산

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4614732A (en) * 1984-10-26 1986-09-30 Warner-Lambert Company N6 -acenaphthyl adenosines and analogs thereof
DE68911951T2 (de) * 1988-02-22 1994-06-01 American Cyanamid Co 5-(Substituierte Amino)-8-(phenyl oder substituierte phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one.

Also Published As

Publication number Publication date
ES2102371T3 (es) 1997-08-01
NO177749C (no) 1995-11-15
CS41991A3 (en) 1991-09-15
NO910686D0 (no) 1991-02-20
NZ237123A (en) 1994-07-26
ZA911260B (en) 1992-10-28
HU910584D0 (en) 1991-09-30
EP0443312A3 (en) 1992-02-19
ATE152723T1 (de) 1997-05-15
HUT60500A (en) 1992-09-28
IE910575A1 (en) 1991-08-28
JP3046851B2 (ja) 2000-05-29
FI93963C (fi) 1995-06-26
US5013737A (en) 1991-05-07
PH27464A (en) 1993-07-09
PL166100B1 (pl) 1995-03-31
IL97289A0 (en) 1992-05-25
EP0443312A2 (en) 1991-08-28
CA2036589A1 (en) 1991-08-22
AU7122591A (en) 1991-08-22
PL289157A1 (en) 1992-06-26
PT96805A (pt) 1991-10-31
FI93963B (fi) 1995-03-15
KR0183395B1 (ko) 1999-05-01
DE69125962D1 (de) 1997-06-12
SG47638A1 (en) 1998-04-17
PT96805B (pt) 1998-07-31
CZ285584B6 (cs) 1999-09-15
DE69125962T2 (de) 1997-10-16
AU640202B2 (en) 1993-08-19
SK279997B6 (sk) 1999-06-11
GR3024063T3 (en) 1997-10-31
JPH04211086A (ja) 1992-08-03
DK0443312T3 (da) 1997-11-17
FI910816A0 (fi) 1991-02-20
NO177749B (no) 1995-08-07
FI910816A (fi) 1991-08-22
NO910686L (no) 1991-08-22
EP0443312B1 (en) 1997-05-07

Similar Documents

Publication Publication Date Title
KR100353014B1 (ko) 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
KR19990028756A (ko) 피롤로피리미딘 및 그들의 제조 방법
AU2009276420A1 (en) Piperidine derivatives as JAK3 inhibitors
US5169850A (en) N-(dialkylamino)methylene)-substituted pyrazolo(1,5-a)-pyrimidine-3-carboxamides and N-(dialkylamino)methylene-substituted-4,5-dihydropyrazolo-(1,5-a)-pyrimidine-3-carboxamides
US5840895A (en) Triazole intermediates for tricyclic benzazepine and benzothiazepine derivatives
WO2011150356A1 (en) Heterocyclic compounds as janus kinase inhibitors
JPS63183584A (ja) ４，５−ジヒドロおよび４，５，６，７−テトラヒドロピラゾロ〔１，５−ａ〕ピリミジン類
US5565463A (en) 9-subtituted-8-unsubstituted-9-deazaguanines
US4904658A (en) Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones
EP0264773A1 (en) 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines
US5013737A (en) 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
US4497814A (en) 2-(Pyridinyl)-1,2,4-triazolo[1,5-a]pyrimidines and derivatives useful in increasing cardiac contractility
US4916137A (en) 5-(Substituted-amino)-8-(phenyl or substituted-phenyl)-3H,6H-1,4,5A,8A-tetraazaacenaphthylen-3-ones and treatment of neural behavior disorders
EP0997463A1 (en) Naphthyridine derivatives
EP0329940B1 (en) 5-(substituted)amino)-8- (phenyl or substituted phenyl)-3H,6H-1,2,5,a,8 a-tetraazaacenaphthylen-3-ones
US5059691A (en) N-((dialkylamino)methylene)-substituted pyrazolo (1,5-A)-pyrimidine-3-carboxamides and N-((dialkylamino)methylene)-substituted-4,5-dihydropyrazolo-(1,5-A)-pyrimidine-3-carboxamides
JPS61227584A (ja) ポリアザ複素環誘導体
US4888345A (en) 4,8-disubstituted-1,2-dihydro and 1,2,3,4-tetrahydroimidazo-[1,5-a] pyrimidines
FR2640975A1 (hu)

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees