ES2102371T3 - 3h,6h-1,4,5a,8a-tetraazaacenaftilen-3,5(4h)-dionas. - Google Patents

3h,6h-1,4,5a,8a-tetraazaacenaftilen-3,5(4h)-dionas.

Info

Publication number
ES2102371T3
ES2102371T3 ES91100189T ES91100189T ES2102371T3 ES 2102371 T3 ES2102371 T3 ES 2102371T3 ES 91100189 T ES91100189 T ES 91100189T ES 91100189 T ES91100189 T ES 91100189T ES 2102371 T3 ES2102371 T3 ES 2102371T3
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
chem
tetraazaacenaftilen
dionas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91100189T
Other languages
English (en)
Inventor
Shin Shyong Tseng
Joseph William Epstein
Jeremy Ian Levin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2102371T3 publication Critical patent/ES2102371T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBEN NUEVAS 2, 4, 8-TRISUSTITUIDAS5A, 8A-TETRAAZAACENAFTILENO-3, 5(4H)-DIONAS QUE SON UTILES COMO AGENTES CONTRA LA HIPERTENSION Y AUXIOLITICOS.
ES91100189T 1990-02-21 1991-01-08 3h,6h-1,4,5a,8a-tetraazaacenaftilen-3,5(4h)-dionas. Expired - Lifetime ES2102371T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/482,568 US5013737A (en) 1988-02-22 1990-02-21 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones

Publications (1)

Publication Number Publication Date
ES2102371T3 true ES2102371T3 (es) 1997-08-01

Family

ID=23916572

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91100189T Expired - Lifetime ES2102371T3 (es) 1990-02-21 1991-01-08 3h,6h-1,4,5a,8a-tetraazaacenaftilen-3,5(4h)-dionas.

Country Status (24)

Country Link
US (1) US5013737A (es)
EP (1) EP0443312B1 (es)
JP (1) JP3046851B2 (es)
KR (1) KR0183395B1 (es)
AT (1) ATE152723T1 (es)
AU (1) AU640202B2 (es)
CA (1) CA2036589A1 (es)
CZ (1) CZ285584B6 (es)
DE (1) DE69125962T2 (es)
DK (1) DK0443312T3 (es)
ES (1) ES2102371T3 (es)
FI (1) FI93963C (es)
GR (1) GR3024063T3 (es)
HU (1) HUT60500A (es)
IE (1) IE910575A1 (es)
IL (1) IL97289A (es)
NO (1) NO177749C (es)
NZ (1) NZ237123A (es)
PH (1) PH27464A (es)
PL (1) PL166100B1 (es)
PT (1) PT96805B (es)
SG (1) SG47638A1 (es)
SK (1) SK279997B6 (es)
ZA (1) ZA911260B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1129096E (pt) * 1998-11-12 2003-09-30 Neurocrine Biosciences Inc Antagonistas de receptor de crf e metodos de tratamento relacionados com os mesmos
WO2000027846A2 (en) * 1998-11-12 2000-05-18 Neurocrine Biosciences, Inc. Crf receptor antagonists and methods relating thereto
US20070219183A1 (en) * 2006-03-17 2007-09-20 Wyeth Dihydropyrazolo[1,5-A]pyrimidine and dihydroimidazo[1,5-A]pyrimidine derivatives and methods of use thereof
CA2643968A1 (en) * 2006-03-17 2007-09-27 Wyeth Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof
KR200480580Y1 (ko) * 2015-09-30 2016-06-13 김영직 어린이용 우산

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4614732A (en) * 1984-10-26 1986-09-30 Warner-Lambert Company N6 -acenaphthyl adenosines and analogs thereof
EP0329940B1 (en) * 1988-02-22 1994-01-05 American Cyanamid Company 5-(substituted)amino)-8- (phenyl or substituted phenyl)-3H,6H-1,2,5,a,8 a-tetraazaacenaphthylen-3-ones

Also Published As

Publication number Publication date
AU640202B2 (en) 1993-08-19
NO177749B (no) 1995-08-07
CS41991A3 (en) 1991-09-15
SG47638A1 (en) 1998-04-17
SK279997B6 (sk) 1999-06-11
NO177749C (no) 1995-11-15
AU7122591A (en) 1991-08-22
DE69125962D1 (de) 1997-06-12
PH27464A (en) 1993-07-09
NO910686D0 (no) 1991-02-20
EP0443312A2 (en) 1991-08-28
DE69125962T2 (de) 1997-10-16
DK0443312T3 (da) 1997-11-17
JP3046851B2 (ja) 2000-05-29
CA2036589A1 (en) 1991-08-22
ATE152723T1 (de) 1997-05-15
NZ237123A (en) 1994-07-26
PT96805B (pt) 1998-07-31
PT96805A (pt) 1991-10-31
FI910816A (fi) 1991-08-22
FI910816A0 (fi) 1991-02-20
KR0183395B1 (ko) 1999-05-01
IL97289A (en) 1995-06-29
FI93963C (fi) 1995-06-26
FI93963B (fi) 1995-03-15
NO910686L (no) 1991-08-22
IE910575A1 (en) 1991-08-28
HUT60500A (en) 1992-09-28
GR3024063T3 (en) 1997-10-31
IL97289A0 (en) 1992-05-25
HU910584D0 (en) 1991-09-30
CZ285584B6 (cs) 1999-09-15
PL289157A1 (en) 1992-06-26
JPH04211086A (ja) 1992-08-03
ZA911260B (en) 1992-10-28
EP0443312B1 (en) 1997-05-07
US5013737A (en) 1991-05-07
EP0443312A3 (en) 1992-02-19
PL166100B1 (pl) 1995-03-31

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