ZA911260B - 2,4,8-trisubstituted-3h,6h-1,4,5a,8a-tetraazaacenaphthylene-3,5-(4h)-diones - Google Patents

2,4,8-trisubstituted-3h,6h-1,4,5a,8a-tetraazaacenaphthylene-3,5-(4h)-diones

Info

Publication number
ZA911260B
ZA911260B ZA911260A ZA911260A ZA911260B ZA 911260 B ZA911260 B ZA 911260B ZA 911260 A ZA911260 A ZA 911260A ZA 911260 A ZA911260 A ZA 911260A ZA 911260 B ZA911260 B ZA 911260B
Authority
ZA
South Africa
Prior art keywords
alkyl
hydrogen
chem
tetraazaacenaphthylene
diones
Prior art date
Application number
ZA911260A
Other languages
English (en)
Inventor
Shin Shyong Tseng
Shyong Tseng Shin
Joseph William Epstein
William Epstein Joseph
Jeremy Ian Levin
Ian Levin Jeremy
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ZA911260B publication Critical patent/ZA911260B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA911260A 1990-02-21 1991-02-20 2,4,8-trisubstituted-3h,6h-1,4,5a,8a-tetraazaacenaphthylene-3,5-(4h)-diones ZA911260B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/482,568 US5013737A (en) 1988-02-22 1990-02-21 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones

Publications (1)

Publication Number Publication Date
ZA911260B true ZA911260B (en) 1992-10-28

Family

ID=23916572

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA911260A ZA911260B (en) 1990-02-21 1991-02-20 2,4,8-trisubstituted-3h,6h-1,4,5a,8a-tetraazaacenaphthylene-3,5-(4h)-diones

Country Status (24)

Country Link
US (1) US5013737A (hu)
EP (1) EP0443312B1 (hu)
JP (1) JP3046851B2 (hu)
KR (1) KR0183395B1 (hu)
AT (1) ATE152723T1 (hu)
AU (1) AU640202B2 (hu)
CA (1) CA2036589A1 (hu)
CZ (1) CZ285584B6 (hu)
DE (1) DE69125962T2 (hu)
DK (1) DK0443312T3 (hu)
ES (1) ES2102371T3 (hu)
FI (1) FI93963C (hu)
GR (1) GR3024063T3 (hu)
HU (1) HUT60500A (hu)
IE (1) IE910575A1 (hu)
IL (1) IL97289A (hu)
NO (1) NO177749C (hu)
NZ (1) NZ237123A (hu)
PH (1) PH27464A (hu)
PL (1) PL166100B1 (hu)
PT (1) PT96805B (hu)
SG (1) SG47638A1 (hu)
SK (1) SK279997B6 (hu)
ZA (1) ZA911260B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1129096E (pt) * 1998-11-12 2003-09-30 Neurocrine Biosciences Inc Antagonistas de receptor de crf e metodos de tratamento relacionados com os mesmos
JP2002529465A (ja) * 1998-11-12 2002-09-10 ニューロクライン バイオサイエンシーズ， インコーポレイテッド Ｃｒｆレセプターアンタゴニストおよびｃｒｆレセプターアンタゴニストに関する方法
US20070219183A1 (en) * 2006-03-17 2007-09-20 Wyeth Dihydropyrazolo[1,5-A]pyrimidine and dihydroimidazo[1,5-A]pyrimidine derivatives and methods of use thereof
EP1996594A2 (en) * 2006-03-17 2008-12-03 Wyeth a Corporation of the State of Delaware Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof
KR200480580Y1 (ko) * 2015-09-30 2016-06-13 김영직 어린이용 우산

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4614732A (en) * 1984-10-26 1986-09-30 Warner-Lambert Company N6 -acenaphthyl adenosines and analogs thereof
DE68911951T2 (de) * 1988-02-22 1994-06-01 American Cyanamid Co 5-(Substituierte Amino)-8-(phenyl oder substituierte phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one.

Also Published As

Publication number Publication date
US5013737A (en) 1991-05-07
PT96805B (pt) 1998-07-31
AU7122591A (en) 1991-08-22
FI93963B (fi) 1995-03-15
JPH04211086A (ja) 1992-08-03
PL166100B1 (pl) 1995-03-31
PT96805A (pt) 1991-10-31
HUT60500A (en) 1992-09-28
NO177749B (no) 1995-08-07
IL97289A (en) 1995-06-29
DE69125962T2 (de) 1997-10-16
ES2102371T3 (es) 1997-08-01
NZ237123A (en) 1994-07-26
JP3046851B2 (ja) 2000-05-29
HU910584D0 (en) 1991-09-30
IL97289A0 (en) 1992-05-25
NO910686D0 (no) 1991-02-20
EP0443312A3 (en) 1992-02-19
SK279997B6 (sk) 1999-06-11
GR3024063T3 (en) 1997-10-31
CA2036589A1 (en) 1991-08-22
EP0443312A2 (en) 1991-08-28
CS41991A3 (en) 1991-09-15
IE910575A1 (en) 1991-08-28
DK0443312T3 (da) 1997-11-17
DE69125962D1 (de) 1997-06-12
NO177749C (no) 1995-11-15
AU640202B2 (en) 1993-08-19
FI93963C (fi) 1995-06-26
PH27464A (en) 1993-07-09
KR0183395B1 (ko) 1999-05-01
PL289157A1 (en) 1992-06-26
ATE152723T1 (de) 1997-05-15
FI910816A0 (fi) 1991-02-20
NO910686L (no) 1991-08-22
SG47638A1 (en) 1998-04-17
FI910816A (fi) 1991-08-22
CZ285584B6 (cs) 1999-09-15
EP0443312B1 (en) 1997-05-07

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