IL95423A - Pulse system for delivery of minocycline once daily - Google Patents

Pulse system for delivery of minocycline once daily

Info

Publication number
IL95423A
IL95423A IL9542390A IL9542390A IL95423A IL 95423 A IL95423 A IL 95423A IL 9542390 A IL9542390 A IL 9542390A IL 9542390 A IL9542390 A IL 9542390A IL 95423 A IL95423 A IL 95423A
Authority
IL
Israel
Prior art keywords
minocycline
medium
coated
deoxy
acid addition
Prior art date
Application number
IL9542390A
Other languages
English (en)
Hebrew (he)
Other versions
IL95423A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL95423A0 publication Critical patent/IL95423A0/xx
Publication of IL95423A publication Critical patent/IL95423A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL9542390A 1989-09-21 1990-08-20 Pulse system for delivery of minocycline once daily IL95423A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41070889A 1989-09-21 1989-09-21

Publications (2)

Publication Number Publication Date
IL95423A0 IL95423A0 (en) 1991-06-30
IL95423A true IL95423A (en) 1994-11-11

Family

ID=23625892

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9542390A IL95423A (en) 1989-09-21 1990-08-20 Pulse system for delivery of minocycline once daily

Country Status (26)

Country Link
US (2) US5300304A (ko)
EP (1) EP0418565B1 (ko)
JP (1) JP3140764B2 (ko)
KR (1) KR100187950B1 (ko)
CN (1) CN1035039C (ko)
AR (1) AR244547A1 (ko)
AT (1) ATE114472T1 (ko)
AU (1) AU624998B2 (ko)
CA (1) CA2025703C (ko)
CZ (1) CZ283048B6 (ko)
DD (1) DD297558A5 (ko)
DE (1) DE69014513T2 (ko)
DK (1) DK0418565T3 (ko)
ES (1) ES2064564T3 (ko)
FI (1) FI96170C (ko)
HK (1) HK1000315A1 (ko)
HU (1) HU221804B1 (ko)
IE (1) IE66389B1 (ko)
IL (1) IL95423A (ko)
NO (1) NO177038C (ko)
NZ (1) NZ235319A (ko)
PH (1) PH30777A (ko)
PL (1) PL164770B1 (ko)
PT (1) PT95353B (ko)
SK (1) SK279358B6 (ko)
ZA (1) ZA907546B (ko)

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DE69014513T2 (de) * 1989-09-21 1995-05-24 American Cyanamid Co System des Typs "einmal täglich" zur gepulsten Minocyclinabgabe.
TW212139B (ko) * 1991-04-15 1993-09-01 Yamanouchi Pharma Co Ltd
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
AU742231B2 (en) * 1994-03-23 2001-12-20 Ortho-Mcneil Pharmaceutical, Inc. Multilayered controlled release pharmaceutical dosage form
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WO2005023184A2 (en) 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CN1332937C (zh) * 2003-12-31 2007-08-22 赤峰东陵药业有限责任公司 新四环霉素类衍生物
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Also Published As

Publication number Publication date
ZA907546B (en) 1991-07-31
PH30777A (en) 1997-10-17
IL95423A0 (en) 1991-06-30
US5300304A (en) 1994-04-05
PT95353A (pt) 1991-08-14
DE69014513D1 (de) 1995-01-12
ES2064564T3 (es) 1995-02-01
CN1035039C (zh) 1997-06-04
EP0418565A2 (en) 1991-03-27
NO904099L (no) 1991-03-22
HU221804B1 (hu) 2003-01-28
JPH03112930A (ja) 1991-05-14
PL286971A1 (en) 1992-01-27
DK0418565T3 (da) 1995-01-23
IE66389B1 (en) 1995-12-27
FI96170C (fi) 1996-05-27
NO177038C (no) 1995-07-12
AR244547A1 (es) 1993-11-30
AU624998B2 (en) 1992-06-25
KR100187950B1 (ko) 1999-06-01
CA2025703C (en) 2002-08-27
FI904634A0 (fi) 1990-09-20
NO904099D0 (no) 1990-09-20
HUT59314A (en) 1992-05-28
CN1050320A (zh) 1991-04-03
KR910005875A (ko) 1991-04-27
PT95353B (pt) 1998-05-29
NZ235319A (en) 1993-03-26
SK455990A3 (en) 1998-10-07
EP0418565B1 (en) 1994-11-30
SK279358B6 (sk) 1998-10-07
EP0418565A3 (en) 1991-09-25
AU6303190A (en) 1991-03-28
FI96170B (fi) 1996-02-15
HK1000315A1 (en) 1998-02-27
DD297558A5 (de) 1992-01-16
IE903398A1 (en) 1991-04-10
CZ455990A3 (en) 1997-08-13
PL164770B1 (pl) 1994-10-31
CZ283048B6 (cs) 1997-12-17
US5413777A (en) 1995-05-09
CA2025703A1 (en) 1991-03-22
JP3140764B2 (ja) 2001-03-05
DE69014513T2 (de) 1995-05-24
ATE114472T1 (de) 1994-12-15
HU906006D0 (en) 1991-03-28
NO177038B (no) 1995-04-03

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