IL88999A - Carbocyclic history of 2D (3-deoxy- (2T) (3D) -Didhydro furin nucleoside and pharmaceutical preparations containing them - Google Patents

Carbocyclic history of 2D (3-deoxy- (2T) (3D) -Didhydro furin nucleoside and pharmaceutical preparations containing them

Info

Publication number
IL88999A
IL88999A IL8899989A IL8899989A IL88999A IL 88999 A IL88999 A IL 88999A IL 8899989 A IL8899989 A IL 8899989A IL 8899989 A IL8899989 A IL 8899989A IL 88999 A IL88999 A IL 88999A
Authority
IL
Israel
Prior art keywords
compound
formula
purin
pharmaceutically acceptable
compounds
Prior art date
Application number
IL8899989A
Other languages
English (en)
Hebrew (he)
Other versions
IL88999A0 (en
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/146,252 external-priority patent/US4916224A/en
Priority claimed from GB888821011A external-priority patent/GB8821011D0/en
Priority claimed from US07/278,652 external-priority patent/US4931559A/en
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of IL88999A0 publication Critical patent/IL88999A0/xx
Publication of IL88999A publication Critical patent/IL88999A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL8899989A 1988-01-20 1989-01-19 Carbocyclic history of 2D (3-deoxy- (2T) (3D) -Didhydro furin nucleoside and pharmaceutical preparations containing them IL88999A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/146,252 US4916224A (en) 1988-01-20 1988-01-20 Dideoxycarbocyclic nucleosides
GB888821011A GB8821011D0 (en) 1988-09-07 1988-09-07 Chemical compounds
US07/278,652 US4931559A (en) 1988-01-20 1988-12-05 Optically-active isomers of dideoxycarbocyclic nucleosides

Publications (2)

Publication Number Publication Date
IL88999A0 IL88999A0 (en) 1989-08-15
IL88999A true IL88999A (en) 1994-12-29

Family

ID=27264063

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8899989A IL88999A (en) 1988-01-20 1989-01-19 Carbocyclic history of 2D (3-deoxy- (2T) (3D) -Didhydro furin nucleoside and pharmaceutical preparations containing them

Country Status (29)

Country Link
JP (1) JP2793825B2 (es)
KR (1) KR0127137B1 (es)
AT (1) AT397801B (es)
AU (2) AU626278B2 (es)
BE (1) BE1003815A4 (es)
CA (1) CA1339896C (es)
CH (1) CH679152A5 (es)
DE (1) DE3901502C2 (es)
DK (1) DK175131B1 (es)
ES (1) ES2010091A6 (es)
FI (1) FI93546C (es)
FR (1) FR2626002B1 (es)
GB (1) GB2217320B (es)
GR (1) GR890100033A (es)
HU (1) HU203755B (es)
IE (1) IE62275B1 (es)
IL (1) IL88999A (es)
IT (1) IT1229531B (es)
LU (1) LU87437A1 (es)
MY (1) MY103801A (es)
NL (1) NL8900122A (es)
NO (1) NO169123C (es)
NZ (1) NZ227663A (es)
OA (1) OA09031A (es)
PL (1) PL163814B1 (es)
PT (1) PT89482B (es)
RU (1) RU2114846C1 (es)
SE (1) SE505213C2 (es)
YU (1) YU47791B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1215339B (it) * 1987-01-14 1990-02-08 Co Pharma Corp Srl Procedimento per la preparazione di 9-(idrossialchil)-ipoxantine
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US4939252A (en) * 1989-04-20 1990-07-03 Hoffmann-La Roche Inc. Novel intermediates for the preparation of Carbovir
JP3164361B2 (ja) * 1989-06-27 2001-05-08 ザ ウエルカム ファウンデーション リミテッド 治療用ヌクレオシド
GB8916480D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916479D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916477D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
GB8916478D0 (en) * 1989-07-19 1989-09-06 Glaxo Group Ltd Chemical process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5144034A (en) * 1990-04-06 1992-09-01 Glaxo Inc. Process for the synthesis of cyclopentene derivatives of purines
US5241069A (en) * 1990-04-06 1993-08-31 Glaxo Inc. Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
US5057630A (en) * 1990-04-06 1991-10-15 Glaxo Inc. Synthesis of cyclopentene derivatives
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes
WO1995013277A1 (en) * 1993-11-12 1995-05-18 Merrell Pharmaceuticals Inc. 6-oxo-nucleosides useful as immunosuppressants
GB9721780D0 (en) * 1997-10-14 1997-12-10 Glaxo Group Ltd Process for the synthesis of chloropurine intermediates
DK1124805T3 (da) * 1998-10-30 2003-09-15 Lonza Ag Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler
KR100606625B1 (ko) 1998-10-30 2006-07-28 론자 아게 4-[(2',5'-디아미노-6'-할로피리미딘-4'-일)아미노]-시클로펜트-2-에닐메탄올의 제조 방법
TWI229674B (en) * 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
AR039540A1 (es) 2002-05-13 2005-02-23 Tibotec Pharm Ltd Compuestos microbicidas con contenido de pirimidina o triazina
CN112512529B (zh) 2018-07-27 2024-06-18 富士胶片株式会社 环戊烯嘌呤衍生物或其盐
US20230147129A1 (en) 2020-03-27 2023-05-11 Som Innovation Biotech, S.A. Compounds for use in the treatment of synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) * 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (ja) * 1986-01-30 1987-08-04 Mitsubishi Heavy Ind Ltd 遠心紡糸によるカ−ボン繊維の製造装置
IN164556B (es) * 1986-03-06 1989-04-08 Takeda Chemical Industries Ltd
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.

Also Published As

Publication number Publication date
IT8947546A0 (it) 1989-01-19
AU626278B2 (en) 1992-07-30
ATA10689A (de) 1993-11-15
HUT48887A (en) 1989-07-28
DK175131B1 (da) 2004-06-14
JP2793825B2 (ja) 1998-09-03
AT397801B (de) 1994-07-25
FR2626002B1 (fr) 1994-01-28
GB8901187D0 (en) 1989-03-15
IE62275B1 (en) 1995-01-25
KR890011902A (ko) 1989-08-23
GB2217320B (en) 1992-04-08
YU12389A (en) 1991-10-31
RU2114846C1 (ru) 1998-07-10
DK23489D0 (da) 1989-01-19
CA1339896C (en) 1998-06-02
GR890100033A (el) 1994-03-31
SE8900192D0 (sv) 1989-01-19
FI890286A0 (fi) 1989-01-19
OA09031A (en) 1991-03-31
AU2867189A (en) 1989-07-20
SE505213C2 (sv) 1997-07-14
PL277261A1 (en) 1989-09-18
FI93546C (fi) 1995-04-25
IE890153L (en) 1989-07-20
NL8900122A (nl) 1989-08-16
CH679152A5 (es) 1991-12-31
DE3901502C2 (de) 2002-06-13
IL88999A0 (en) 1989-08-15
PL163814B1 (en) 1994-05-31
LU87437A1 (fr) 1989-08-30
KR0127137B1 (ko) 1997-12-29
DK23489A (da) 1989-07-21
GB2217320A (en) 1989-10-25
NO169123C (no) 1992-05-13
AU1018092A (en) 1992-03-12
YU47791B (sr) 1996-01-09
SE8900192L (sv) 1989-07-21
BE1003815A4 (fr) 1992-06-23
FI93546B (fi) 1995-01-13
HU203755B (en) 1991-09-30
NO890253L (no) 1989-07-21
ES2010091A6 (es) 1989-10-16
DE3901502A1 (de) 1989-07-27
IT1229531B (it) 1991-09-04
PT89482A (pt) 1989-10-04
FI890286A (fi) 1989-07-21
JPH02196788A (ja) 1990-08-03
NZ227663A (en) 1990-09-26
PT89482B (pt) 1994-02-28
FR2626002A1 (fr) 1989-07-21
AU637015B2 (en) 1993-05-13
MY103801A (en) 1993-09-30
NO169123B (no) 1992-02-03
NO890253D0 (no) 1989-01-19

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