DK1124805T3 - Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler - Google Patents

Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler

Info

Publication number
DK1124805T3
DK1124805T3 DK99971416T DK99971416T DK1124805T3 DK 1124805 T3 DK1124805 T3 DK 1124805T3 DK 99971416 T DK99971416 T DK 99971416T DK 99971416 T DK99971416 T DK 99971416T DK 1124805 T3 DK1124805 T3 DK 1124805T3
Authority
DK
Denmark
Prior art keywords
diamino
enylmethanols
cyclopent
amino
pyrimidin
Prior art date
Application number
DK99971416T
Other languages
English (en)
Inventor
Walter Brieden
Elie Saikali
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK1124805T3 publication Critical patent/DK1124805T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK99971416T 1998-10-30 1999-10-29 Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler DK1124805T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98120529 1998-10-30
US14610599P 1999-07-29 1999-07-29
PCT/EP1999/008270 WO2000026193A1 (de) 1998-10-30 1999-10-29 Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen

Publications (1)

Publication Number Publication Date
DK1124805T3 true DK1124805T3 (da) 2003-09-15

Family

ID=56289961

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99971416T DK1124805T3 (da) 1998-10-30 1999-10-29 Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler

Country Status (14)

Country Link
EP (1) EP1124805B1 (da)
JP (1) JP4457496B2 (da)
CN (1) CN1115338C (da)
AT (1) ATE240945T1 (da)
AU (1) AU1158000A (da)
CA (1) CA2348374C (da)
CZ (1) CZ300155B6 (da)
DK (1) DK1124805T3 (da)
ES (1) ES2200594T3 (da)
HU (1) HU227559B1 (da)
IL (1) IL142760A (da)
PL (1) PL198180B1 (da)
SK (1) SK285271B6 (da)
WO (1) WO2000026193A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100606625B1 (ko) 1998-10-30 2006-07-28 론자 아게 4-[(2',5'-디아미노-6'-할로피리미딘-4'-일)아미노]-시클로펜트-2-에닐메탄올의 제조 방법
KR101591656B1 (ko) 2007-01-10 2016-02-19 엠에스디 이탈리아 에스.알.엘. 폴리(ａｄｐ-리보오스) 폴리머라아제(ｐａｒｐ) 억제제로서의 아미드 치환된 인다졸
MX337421B (es) 2008-01-08 2016-03-04 Merck Sharp & Dohme Sales farmaceuticamente aceptables de 2-{4-[(3s)-piperidin-3-il]fe nil}-2h-indazol-7-carboxamida.
CN103626745B (zh) * 2013-12-04 2016-02-24 青岛黄海制药有限责任公司 一种替卡格雷中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1003815A4 (fr) * 1988-01-20 1992-06-23 Univ Minnesota Nucleosides dideoxydidehydrocarbocyliques et composition pharmaceutique les contenant.
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
CN1224697C (zh) * 1996-05-30 2005-10-26 隆萨股份公司 氨基醇及其衍生物的制备方法

Also Published As

Publication number Publication date
EP1124805B1 (de) 2003-05-21
PL347503A1 (en) 2002-04-08
WO2000026193A1 (de) 2000-05-11
CN1115338C (zh) 2003-07-23
CA2348374A1 (en) 2000-05-11
ES2200594T3 (es) 2004-03-01
JP4457496B2 (ja) 2010-04-28
ATE240945T1 (de) 2003-06-15
SK5692001A3 (en) 2001-12-03
JP2003500333A (ja) 2003-01-07
HUP0104045A2 (hu) 2002-05-29
IL142760A (en) 2005-12-18
IL142760A0 (en) 2002-03-10
CA2348374C (en) 2009-04-07
SK285271B6 (sk) 2006-10-05
AU1158000A (en) 2000-05-22
CZ300155B6 (cs) 2009-02-25
HUP0104045A3 (en) 2002-07-29
EP1124805A1 (de) 2001-08-22
HU227559B1 (en) 2011-08-29
CZ20011486A3 (cs) 2001-10-17
CN1325386A (zh) 2001-12-05
PL198180B1 (pl) 2008-06-30

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