BR9814152A - "processo para preparar compostos de ar(alqu)iluracila, intermediários para esse propósito e processos para sua preparação" - Google Patents

"processo para preparar compostos de ar(alqu)iluracila, intermediários para esse propósito e processos para sua preparação"

Info

Publication number
BR9814152A
BR9814152A BR9814152-0A BR9814152A BR9814152A BR 9814152 A BR9814152 A BR 9814152A BR 9814152 A BR9814152 A BR 9814152A BR 9814152 A BR9814152 A BR 9814152A
Authority
BR
Brazil
Prior art keywords
alkyl
processes
preparation
intermediates
iluracil
Prior art date
Application number
BR9814152-0A
Other languages
English (en)
Inventor
Bernd Gallenkamp
Reinhard Lantzsch
Lothar Rohe
Lubbertus Mulder
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BR9814152A publication Critical patent/BR9814152A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/16—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO PARA PREPARAR COMPOSTOS DE AR(ALQU)ILURACILA, INTERMEDIáRIOS PARA ESSE PROPóSITO E PROCESSOS PARA SUA PREPARAçãO"<D>. A invenção refere-se a um processo para preparar compostos de ar(alqu)iluracila da fórmula geral (I), na qual A representa uma ligação simples ou representa alcanodiila, Ar representa arila substituída opcionalmente, R¹ representa alquila substituída opcionalmente e R² representa hidrogênio, halogênio ou alquila, e a intermediários novos para esse propósito e a processos para sua preparação.
BR9814152-0A 1997-11-13 1998-11-03 "processo para preparar compostos de ar(alqu)iluracila, intermediários para esse propósito e processos para sua preparação" BR9814152A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19750195A DE19750195A1 (de) 1997-11-13 1997-11-13 Verfahren zur Herstellung von Ar(alk)yluracilen, neue Zwischenprodukte hierfür und Verfahren zu deren Herstellung
PCT/EP1998/006959 WO1999025698A1 (de) 1997-11-13 1998-11-03 Verfahren zur herstellung von ar(alk)yluracilen, neue zwischenprodukte hierfür und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BR9814152A true BR9814152A (pt) 2000-10-03

Family

ID=7848539

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814152-0A BR9814152A (pt) 1997-11-13 1998-11-03 "processo para preparar compostos de ar(alqu)iluracila, intermediários para esse propósito e processos para sua preparação"

Country Status (8)

Country Link
US (2) US6225470B1 (pt)
EP (1) EP1030846B1 (pt)
JP (1) JP2001523669A (pt)
AT (1) ATE245146T1 (pt)
AU (1) AU1559099A (pt)
BR (1) BR9814152A (pt)
DE (2) DE19750195A1 (pt)
WO (1) WO1999025698A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140270A (en) * 1998-09-14 2000-10-31 American Cyanamid Company Process for the preparation of 6-(perfluoroalkyl) uracil compounds from 2-(N,N-disubstituted) amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds
WO2000049002A1 (en) * 1999-02-16 2000-08-24 American Cyanamid Company Processes and intermediates for the preparation of 1,3-oxazin-6-ones and uracils

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3690863A (en) * 1968-04-19 1972-09-12 Du Pont Esters of 3-(carboxyamino)-and 3-(thiocarboxyamino)-2-substituted crotonamides andtheir use as herbicides
US5681794A (en) 1993-08-18 1997-10-28 Bayer Aktiengesellschaft N-cyanoaryl-nitrogen heterocycles
EP0648749B1 (de) 1993-08-18 1997-12-10 Bayer Ag N-Cyanoaryl-Stickstoffheterocyclen
WO1995032952A1 (en) * 1994-05-27 1995-12-07 Ciba-Geigy Ag Process for the preparation of 3-aryluracils
DE19604582A1 (de) * 1996-02-08 1997-08-14 Bayer Ag Verfahren zur Herstellung von substituierten Cyanophenyluracilen, neue substituierte Aminoalkensäure-cyanophenylamide als Zwischenprodukte hierfür und Verfahren zu deren Herstellung
DE19612032A1 (de) * 1996-03-27 1997-10-09 Basf Ag Substituierte 1-Methyl-3-benzyluracile

Also Published As

Publication number Publication date
DE19750195A1 (de) 1999-05-20
ATE245146T1 (de) 2003-08-15
WO1999025698A1 (de) 1999-05-27
EP1030846A1 (de) 2000-08-30
US6225470B1 (en) 2001-05-01
US20020022727A1 (en) 2002-02-21
JP2001523669A (ja) 2001-11-27
EP1030846B1 (de) 2003-07-16
DE59809031D1 (de) 2003-08-21
US6476224B2 (en) 2002-11-05
AU1559099A (en) 1999-06-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A,8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007.