ATE267808T1 - Verfahren zur herstellung von 2,5- disubstituierten pyridinen - Google Patents
Verfahren zur herstellung von 2,5- disubstituierten pyridinenInfo
- Publication number
- ATE267808T1 ATE267808T1 AT98114969T AT98114969T ATE267808T1 AT E267808 T1 ATE267808 T1 AT E267808T1 AT 98114969 T AT98114969 T AT 98114969T AT 98114969 T AT98114969 T AT 98114969T AT E267808 T1 ATE267808 T1 AT E267808T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- compound
- chem
- signifies
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 2,5-disubstituted pyridine Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/08—Preparation by ring-closure
- C07D213/09—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles
- C07D213/10—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles from acetaldehyde or cyclic polymers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97114269 | 1997-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE267808T1 true ATE267808T1 (de) | 2004-06-15 |
Family
ID=8227241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98114969T ATE267808T1 (de) | 1997-08-19 | 1998-08-10 | Verfahren zur herstellung von 2,5- disubstituierten pyridinen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6080866A (de) |
| EP (1) | EP0897914B1 (de) |
| JP (1) | JP3025239B2 (de) |
| KR (1) | KR100275663B1 (de) |
| CN (1) | CN1103335C (de) |
| AT (1) | ATE267808T1 (de) |
| CA (1) | CA2245169C (de) |
| DE (1) | DE69824090T2 (de) |
| DK (1) | DK0897914T3 (de) |
| ES (1) | ES2221696T3 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743783B1 (en) * | 1993-12-01 | 2004-06-01 | Marine Polymer Technologies, Inc. | Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine |
| US6417360B1 (en) | 1999-03-03 | 2002-07-09 | Hoffmann-La Roche Inc. | Heterocyclic sulfonamides |
| ZA200002318B (en) * | 1999-05-22 | 2000-11-16 | Actelion Pharmaceuticals Ltd | Aqueous pharmaceutical composition. |
| NZ599605A (en) * | 2007-02-19 | 2013-11-29 | Marinepolymer Tech Inc | Hemostatic compositions and therapeutic regimens |
| CN103108638B (zh) | 2010-04-15 | 2016-11-09 | 海洋聚合物技术公司 | 聚-n-乙酰葡萄糖胺纳米纤维的抗菌应用 |
| EP3501284A1 (de) | 2011-04-15 | 2019-06-26 | Marine Polymer Technologies, Inc. | Behandlung von haut-krankheiten mit poly-n-acetylglucosamin-nanofasern |
| JP2023548185A (ja) | 2020-11-05 | 2023-11-15 | イドーシア ファーマシューティカルズ リミテッド | クラゾセンタン二ナトリウム塩の安定な結晶性水和物 |
| KR20240121242A (ko) | 2021-12-17 | 2024-08-08 | 넥세라 파마 씨오., 엘티디. | 클라조센탄 디소듐 염, 이의 제조 및 이를 포함하는 약학 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU571683B2 (en) * | 1984-05-23 | 1988-04-21 | Zeneca Ag Products Inc. | 2-substituted-5-methylpyridines from methylcyclobutane- carbonitrile, valeronitrile and pentenonitrile intermediates |
| DE4223013A1 (de) * | 1992-07-13 | 1994-01-20 | Bayer Ag | Verfahren zur Herstellung von 2,5-disubstituierten Pyridinen |
| CA2162630C (en) * | 1994-11-25 | 2007-05-01 | Volker Breu | Sulfonamides |
| US5837708A (en) * | 1994-11-25 | 1998-11-17 | Hoffmann-La Roche Inc. | Sulphonamides |
| TW313568B (de) * | 1994-12-20 | 1997-08-21 | Hoffmann La Roche |
-
1998
- 1998-08-10 DE DE69824090T patent/DE69824090T2/de not_active Expired - Lifetime
- 1998-08-10 EP EP98114969A patent/EP0897914B1/de not_active Expired - Lifetime
- 1998-08-10 ES ES98114969T patent/ES2221696T3/es not_active Expired - Lifetime
- 1998-08-10 AT AT98114969T patent/ATE267808T1/de active
- 1998-08-10 DK DK98114969T patent/DK0897914T3/da active
- 1998-08-17 CN CN98118370A patent/CN1103335C/zh not_active Expired - Lifetime
- 1998-08-18 JP JP10231239A patent/JP3025239B2/ja not_active Expired - Lifetime
- 1998-08-18 CA CA002245169A patent/CA2245169C/en not_active Expired - Lifetime
- 1998-08-18 KR KR1019980033472A patent/KR100275663B1/ko not_active Expired - Lifetime
- 1998-08-18 US US09/136,118 patent/US6080866A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK0897914T3 (da) | 2004-09-27 |
| CA2245169A1 (en) | 1999-02-19 |
| EP0897914B1 (de) | 2004-05-26 |
| CN1103335C (zh) | 2003-03-19 |
| JP3025239B2 (ja) | 2000-03-27 |
| KR19990023680A (ko) | 1999-03-25 |
| CN1210105A (zh) | 1999-03-10 |
| EP0897914A1 (de) | 1999-02-24 |
| KR100275663B1 (ko) | 2000-12-15 |
| DE69824090D1 (de) | 2004-07-01 |
| CA2245169C (en) | 2004-08-10 |
| ES2221696T3 (es) | 2005-01-01 |
| US6080866A (en) | 2000-06-27 |
| JPH11116554A (ja) | 1999-04-27 |
| DE69824090T2 (de) | 2005-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE223900T1 (de) | Verfahren zur herstellung von 4- trifluormethylnicotinsäure | |
| ATE145891T1 (de) | Verfahren zur herstellung von alkoxyiminoacetamid-derivaten und ein zwischenproduckt dafür | |
| DE69534029D1 (de) | Herstellung von Camptothecinderivaten durch intramolekulare Cyclisierung | |
| ATE117672T1 (de) | Verfahren zur herstellung von nitrilen. | |
| DE59502882D1 (de) | Verfahren zur Herstellung von Benzyl-piperidylmethylindanonen | |
| ATE267808T1 (de) | Verfahren zur herstellung von 2,5- disubstituierten pyridinen | |
| DK539589D0 (da) | Fremgangsmaade til fremstilling af 3-oxo-4-azasteroider | |
| ATE138376T1 (de) | Verfahren zur herstellung von benzylphthalazinonderivaten und von deren salzen | |
| ATE115567T1 (de) | Verfahren zur herstellung von halogensulfonyl- substituierten pyridinen. | |
| TW357056B (en) | Herbicides | |
| DK1124805T3 (da) | Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler | |
| EP1010684A4 (de) | Verfahren zur herstellung von 3,4-dihydroxy-3cyclobuten-1,2-dion | |
| ATE189453T1 (de) | Verfahren zur herstellung von 2-cyanobiphenyl- verbindungen | |
| ATE135693T1 (de) | Halogeno-4-methylpyrazole und verfahren zu ihrer herstellung | |
| DK0412529T3 (da) | Hidtil ukendte imidazolderivater, fremgangsmåde til fremstilling deraf og midler mod mavesår indeholdende disse | |
| ATE299498T1 (de) | Verfahren zur herstellung von imidazolderivaten | |
| DE69706504D1 (de) | Verfahren zur herstellung von 3,4-dihydroxy-3-cyclobuten-1,2-dion | |
| ATE223377T1 (de) | Verfahren zur herstellung von difluoracetophenon- derivaten | |
| ATE180769T1 (de) | Verfahren zur herstellung von n-alkylacetamiden | |
| ATE256113T1 (de) | Verfahren zur herstellung von arylamiden heteroaromatischer carbonsäuren | |
| ATE59375T1 (de) | Verfahren zur herstellung von polyenaldehyden. | |
| ATE206109T1 (de) | Verfahren zur herstellung von carbamoylmethylharnstoff-derivaten | |
| DE69834853D1 (de) | 1H-pyrrolo i1,2-böi1,2,4ötriazolederivate, Zwischenprodukte und Verfahren zur Herstellung von 1H-1,2,4,-triazol-5-yl Essigsäureesterderivate | |
| ATE244701T1 (de) | Verfahren zur herstellung von arylsulfenylhalogeniden |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0897914 Country of ref document: EP |