CZ20011486A3 - Způsob výroby 4-[(2`,5`-diamino-6`-halogenpyrimidin-4`-yl)amino]-cyklopent-2-enylmethanolu - Google Patents

Způsob výroby 4-[(2`,5`-diamino-6`-halogenpyrimidin-4`-yl)amino]-cyklopent-2-enylmethanolu

Info

Publication number
CZ20011486A3
CZ20011486A3 CZ20011486A CZ20011486A CZ20011486A3 CZ 20011486 A3 CZ20011486 A3 CZ 20011486A3 CZ 20011486 A CZ20011486 A CZ 20011486A CZ 20011486 A CZ20011486 A CZ 20011486A CZ 20011486 A3 CZ20011486 A3 CZ 20011486A3
Authority
CZ
Czechia
Prior art keywords
diamino
enylmethanol
cyclopent
amino
halopyrimidin
Prior art date
Application number
CZ20011486A
Other languages
English (en)
Other versions
CZ300155B6 (cs
Inventor
Walter Brieden
Elie Saikali
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of CZ20011486A3 publication Critical patent/CZ20011486A3/cs
Publication of CZ300155B6 publication Critical patent/CZ300155B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CZ20011486A 1998-10-30 1999-10-29 Zpusob výroby 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyklopent-2-enylmethanolu CZ300155B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98120529 1998-10-30
US14610599P 1999-07-29 1999-07-29

Publications (2)

Publication Number Publication Date
CZ20011486A3 true CZ20011486A3 (cs) 2001-10-17
CZ300155B6 CZ300155B6 (cs) 2009-02-25

Family

ID=56289961

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20011486A CZ300155B6 (cs) 1998-10-30 1999-10-29 Zpusob výroby 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyklopent-2-enylmethanolu

Country Status (14)

Country Link
EP (1) EP1124805B1 (cs)
JP (1) JP4457496B2 (cs)
CN (1) CN1115338C (cs)
AT (1) ATE240945T1 (cs)
AU (1) AU1158000A (cs)
CA (1) CA2348374C (cs)
CZ (1) CZ300155B6 (cs)
DK (1) DK1124805T3 (cs)
ES (1) ES2200594T3 (cs)
HU (1) HU227559B1 (cs)
IL (1) IL142760A (cs)
PL (1) PL198180B1 (cs)
SK (1) SK285271B6 (cs)
WO (1) WO2000026193A1 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6433170B1 (en) 1998-10-30 2002-08-13 Lonza Group Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-yl)amino]- cyclopent-2-enylmethanols
EA016079B1 (ru) 2007-01-10 2012-01-30 Институто Ди Ричерке Ди Биолоджиа Молеколаре П. Анджелетти Спа Амидзамещенные индазолы в качестве ингибиторов поли(adp-рибоза)полимеразы (parp)
NZ586675A (en) 2008-01-08 2012-04-27 Merck Sharp & Dohme Pharmaceutically acceptable salts of 2-{ 4-[(3s)-piperidin-3- yl]phenyl} -2h-indazole-7-carboxamide
CN103626745B (zh) * 2013-12-04 2016-02-24 青岛黄海制药有限责任公司 一种替卡格雷中间体的制备方法
CN113330007A (zh) 2018-10-03 2021-08-31 特沙诺有限公司 尼拉帕利游离碱的晶体形式

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA09031A (en) * 1988-01-20 1991-03-31 Univ Minnesota Dideoxydidehydrocarbocyclic nucleosides
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
CA2145928C (en) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide, and a process for its preparation
HU226141B1 (en) * 1996-05-30 2008-05-28 Lonza Ag Process for the preparation of amino alcohols and derivatives thereof

Also Published As

Publication number Publication date
DK1124805T3 (da) 2003-09-15
IL142760A (en) 2005-12-18
ES2200594T3 (es) 2004-03-01
IL142760A0 (en) 2002-03-10
SK5692001A3 (en) 2001-12-03
CZ300155B6 (cs) 2009-02-25
EP1124805B1 (de) 2003-05-21
PL347503A1 (en) 2002-04-08
HU227559B1 (en) 2011-08-29
AU1158000A (en) 2000-05-22
EP1124805A1 (de) 2001-08-22
CN1325386A (zh) 2001-12-05
HUP0104045A2 (hu) 2002-05-29
ATE240945T1 (de) 2003-06-15
CN1115338C (zh) 2003-07-23
PL198180B1 (pl) 2008-06-30
HUP0104045A3 (en) 2002-07-29
JP2003500333A (ja) 2003-01-07
WO2000026193A1 (de) 2000-05-11
CA2348374A1 (en) 2000-05-11
CA2348374C (en) 2009-04-07
JP4457496B2 (ja) 2010-04-28
SK285271B6 (sk) 2006-10-05

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of fee

Effective date: 20131029